• 대한세포병리학회지
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• 제18권2호
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• pp.112-118
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• 2007

Fine needle aspiration cytology (FNAC) has become a highly preferred, minimally invasive diagnostic tool of choice in the diagnosis of a palpable breast mass owing to its sensitivity, specificity, cost-effectiveness, and expediency. Although breast needle biopsies have been widely employed recently due to the increased detection rate of non-palpable early lesions, the importance of the use of FNAC cannot be underestimated. It comprises part of the diagnostic triad for the breast along with a physical examination and mammography, which together contribute to an increasing diagnostic accuracy. The differential diagnosis of a benign and malignant lesion is of the utmost importance in the diagnosis of breast lesions, and therefore the understanding of the possible diagnostic pitfalls is of great importance.

• 한국조명전기설비학회:학술대회논문집
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• 한국조명전기설비학회 1999년도 학술대회논문집-국제 전기방전 및 플라즈마 심포지엄 Proceedings of 1999 KIIEE Annual Conference-International Symposium of Electrical Discharge and Plasma
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• pp.127-131
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• 1999

In this paper, using a wide-band AE sensor with the frequency range from 100[kHz], the frequency spectra of AE signals generated from the corona discharges of the needle-plane electrode was analyzed to determine the proper ultrasonic sensor. We also examined the relationship between the magnitude of corona discharge and the magnitude of AE signals in peak-to-peak value under the application of 60[Hz] AC high-voltage in oil. From these results, the main frequency spectra of AE signals emitted from the corona discharges of the needle-plane gap were found to be 130[kHz] by the fast fourier transform. The magnitude of AE signals was proportional to the magnitude of corona discharge and discharge current pulse with increasing the applied voltages. Also the detection of corona discharge point location by AE signals was found to be possible by using two sensors.

• 센서학회지
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• 제29권6호
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• pp.427-432
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• 2020

The most lethal foreign body in meat is a needle, and X-ray images are used to detect it. However, because the difference in thickness and fat content is severe depending on the type of meat and the part of the meat, the shade difference and contrast appear severe. This problem causes difficulty in automatic classification. In this paper, we propose a method for generating training patterns by efficient pre-processing and classifying needles in meat using a convolution neural network. Approximately 24000 training patterns and 4000 test patterns were used to verify the proposed method, and an accuracy of 99.8% was achieved.

• Asian Pacific Journal of Cancer Prevention
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• 제15권7호
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• pp.3087-3091
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• 2014

Purpose: To determine the utility of digital rectal examination (DRE), serum total prostate specific antigen (tPSA) estimation, and transrectal ultrasound (TRUS) for the detection of prostate cancer (PCa) in men with lower urinary tract symptoms (LUTS). Materials and Methods: All patients with abnormal DRE, TRUS, or serum tPSA >4ng/ml, in any combination, underwent TRUS-guided needle biopsy. Eight cores of prostatic tissue were obtained from different areas of the peripheral prostate and examined histopathologically for the nature of the pathology. Results: PCa was detected in 151 (50.3%) patients, remaining 149 (49.7%) showed benign changes with or without active prostatitis. PCa was detected in 13 (56.5%), 9 (19.1%), 26 (28.3%), and 103 (74.6%) of patients with tPSA <4 ng/ml, 4-10 ng/ml, 10-20 ng/ml and >20 ng/ml respectively. Only 13 patients with PCa had abnormal DRE and TRUS with serum PSA <4 ng/ml. The detection rate was highest in patients with tPSA >20 ng/ml. The association between tPSA level and cancer detection was statistically significant (p<0.01). Among 209 patients with abnormal DRE and raised serum PSA, PCa was detected in 128 (61.2%). Conclusions: The incidence of PCa increases with increasing serum level of tPSA. The overall screening and detection rate can be further improved by using DRE, TRUS and TRUS-guided prostate needle biopsies.

• 한국전기전자재료학회논문지
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• 제25권9호
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• pp.727-731
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• 2012

This paper dealt with the measurement and analysis of electromagnetic waves radiated from a partial discharge (PD) source in insulation oil to apply condition monitoring of oil-immersed transformers. Two types of narrow-band monopole antennas with the resonant frequency of a 500 MHz and a 1 GHz were designed and fabricated. Also, a needle-plane electrode system was manufactured to simulate PDs and the curvature radius of the needle is 10 ${\mu}m$ and the diameter of the plane is 60 mm. Electromagnetic wave was measured by the PD measurement system with the monopole antennas. Detection sensitivity of the fabricated antenna was compared for the same PD magnitude; 620 $mV_{peak}$ for the 500 MHz antenna and 960 $mV_{peak}$ for the 1 GHz antenna to the PD magnitude of 74 pC. Consequently, the 1 GHz monopole antenna is more effective to detect PDs in oil-immersed transformers.

• 대한세포병리학회지
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• 제10권1호
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• pp.43-53
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• 1999

We retrospectively reviewed the results of 1,850 fine needle aspiration cytology(FNAC) of thyroid nodules performed from 1990 to 1991 in the Department of Pathology, Seoul National University Hospital. Among 1,528 cases and 322 cases aspirated by clinicians and a pathologist, 465 cases(30.4%) and 13 cases(4.0%) of the aspirates were inadequate, respectively. In 227 cases, correlation of the FNAC diagnosis and histologic diagnosis was done. Excluding the inadequate cases, the sensitivity nor the detection of neoplasm(malignancy together with follicular adenoma) was 86.4% and the specificity was 70.7%. The overall diagnostic accuracy was 79.0%. There were 16 false-positive cases(7.0%), and 19 false-negative cases(8.4%). The predictive value of each cytologic diagnosis was 92% in papillary carcinoma, and 100%, in Hashimoto's thyroiditis. The expectancy of malignancy was 52.8% in "suspicious malignancy" and 26.7% in "atypical lesion".

• 한국항해항만학회지
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• 제47권6호
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• pp.410-418
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• 2023

최근 자율운항선박 관련 연구개발과 상용화가 급속하게 진행됨과 동시에 자율운항선박의 감항성 확보를 위하여 선박에 설치된 각종 장비 상태를 원격지에서 검사할 수 있는 방법 역시 연구되고 있다. 특히, 각종 장비에 부착된 아날로그 게이지의 값을 영상처리를 통해 획득할 수 있는 방법이 주요 이슈로 부각되고 있는데, 그 이유는 영상처리 기법을 이용하면 이미 설치되었거나 또는 설치 예정인 다수의 장비를 변형 또는 변경하지 않고 비접촉식으로 게이지의 값을 검출할 수 있어서 장비의 변형 또는 변경에 따른 선급의 형식승인 등이 필요하지 않은 장점이 있기 때문이다. 본 연구의 목적은 잡음이 포함된 아날로그 게이지의 영상 중에서 동적으로 변하는 지시바늘의 객체를 식별하는데 있다. 지시바늘 객체의 위치는 정확한 게이지 값의 판독에 영향을 미치는데, 게이지 값을 정확하게 판독하기 위해서는 우선하여 지시바늘 객체의 식별이 중요하다. 지시바늘 객체의 식별 작업을 위한 영상은 비상소화펌프 모형에 부착한 수압 측정용 아날로그 게이지를 이용하여 획득하였다. 획득한 영상은 가우시안 필터와 임계처리 그리고 모폴로지 연산 등을 통해서 사전처리한 후, 허프 변환을 통해서 지시바늘의 객체를 식별하였다. 실험결과, 잡음이 포함된 아날로그 게이지의 영상에서 지시바늘의 중심과 객체가 식별됨을 확인하였고, 그 결과 본 연구에 적용한 영상처리 방법이 선박에 장착된 아날로그 게이지의 객체 식별에 적용될 수 있음을 알았다. 본 연구는 자율운항선박의 원격검사를 위한 하나의 영상처리 방법으로 적용될 것으로 기대된다.

• Journal of Nutrition and Health
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• 제24권3호
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• pp.199-205
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• 1991

비타민 A의 활성 대사물인 비타민 A arid(retinoir acid, Rh)를 사람의 간 조직내에서 처음으로 검출하고, 측정하는 방법을 고안하였다. Reverse phase HPLC에 gradient elution을 사용하는 이 방법은 Multiwavelength 검출법을 이용하여 RA, 비타민 A, 비타민 E 및 카로티노이드를 모두 약 30mg정도의 시료로부터 검출할 수 있었다. HPLC 분석에 소요되는 시간은 시료당 20분으로 상당히 신속하며 또 예민하다. 간 조직내의 총비타민 A량에 대한 Rh의 비율은 비타민 A의 축적량에 관계없이 일정한 편으로 약 $2.4\pm0.2%로$ 나타났다. RA의 간 조직내의 검출은 RA가 비타민 A의 체내 대사산물임을 다시 한번 확인시켰으며, 그 함량에 대한 정보는 총비타민 A량과 함께 비타민 A 영양 상태 판정에 보다 좋은 지표가 될 것이다. 특히 간 조직의 needle biopsy가 필요한 질병 상태의 경우, 비타민 A의 기능적 영양 상태판정을 가능하게 하여 질병의 진단 및 처치에 도움이 되리라 사료된다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.10039-10043
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• 2014

Background: In Pakistan thyroid cancer is responsible for 1.2% cases of all malignant tumors. Ultrasonography (US) is helpful in detecting cancerous thyroid nodules on basis of different features like echogenicity, margins, microcalcifications, size, shape and abnormal neck lymph nodes. We therefore aimed to calculate diagnostic accuracy of ultrasound in detection of carcinoma in thyroid nodules taking fine needle aspiration cytology as the reference standard. Materials and Methods: A cross-sectional analytical study was designed to prospectively collect data from December 2010 till December 2012 from the Department of Radiology in Aga Khan University Hospital, Karachi, Pakistan. A total of 100 patients of both genders were enrolled after informed consent via applying non-probability consecutive sampling technique. Patients referred to Radiology department of Aga Khan University to perform thyroid ultrasound followed by fine-needle aspiration cytology of thyroid nodules were included. They were excluded if proven for thyroid malignancy or if their US or FNAC was conducted outside our institution. Results: The subjects comprised 76 (76%) females and 24 males. Mean age was $41.8{\pm}SD$ 12.3 years. Sensitivity and specificity with 95%CI of ultrasound in differentiating malignant thyroid nodule from benign thyroid nodule calculated to be 91.7% (95%CI, 0.72-0.98) and 78.94% (0.68-0.87) respectively. Reported positive predictive value and negative PV were 57.9% (0.41-0.73) and 96.8% (0.88-0.99) and overall accuracy was 82%. Likelihood ratio (LR) positive was computed to be 4.3 and LR negative was 0.1. Conclusions: Ultrasonography has a high diagnostic accuracy in detecting malignancy in thyroid nodules on the basis of features like echogenicity, margins, micro calcifications and shape.

• Journal of Yeungnam Medical Science
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• 제36권2호
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• pp.109-114
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• 2019

Background: Transforaminal epidural block (TFEB) is an effective treatment option for radicular pain. To reduce complications from intravascular injection during TFEB, use of imaging modalities such as real-time fluoroscopy (RTF) or digital subtraction angiography (DSA) has been recommended. In this study, we investigated whether DSA improved the detection of intravascular injection during TFEB at the whole spine level compared to RTF. Methods: We prospectively examined 316 patients who underwent TFEB. After confirmation of final needle position using biplanar fluoroscopy, 2 mL of nonionic contrast medium was injected at a rate of 0.5 mL/s under RTF; 30 s later, 2 mL of nonionic contrast medium was injected at a rate of 0.5 mL/s under DSA. Results: Thirty-six intravascular injections were detected for an overall rate of 11.4% using RTF, with 45 detected for a rate of 14.2% using DSA. The detection rate using DSA was statistically different from that using RTF (p=0.004). DSA detected a significantly higher proportion of intravascular injections at the cervical level than at the thoracic (p=0.009) and lumbar (p=0.011) levels. Conclusion: During TFEB at the whole spine level, DSA was better than RTF for the detection of intravascular injection. Special attention is advised for cervical TFEB, because of a significantly higher intravascular injection rate at this level than at other levels.