• The Korean Journal of Cytopathology
• /
• v.8 no.2
• /
• pp.194-198
• /
• 1997

Extraskeletal mesenchymal chondrosarcoma is a relatively rare tumor and its cytologic findings have rarely been reported. We experienced a case of mesenchymal chondrosarcoma of soft tissue of the right lateral neck diagnosed by fine needle aspiration biopsy in a 59 year-old man. Cytologic findings showed two cell components. One was an undifferentiated, small cell component with moderate amount of cytoplasm and spindle nuclei. The second population was a chondroid component. These cytologic findings were diagnostic to mesenchymal chondrosarcoma.

• Journal of Korean Neurosurgical Society
• /
• v.48 no.3
• /
• pp.294-297
• /
• 2010

Abnormalities of the posterior arch, including congenitally absent cervical pedicle and cervical spondylolysis, are rare entities that are usually found incidentally on neck radiographs. It is important to recognize these characteristic radiological features because their radiographic appearance may cause them to be confused with more serious entities such as fractures, locked facets, and tumor-induced bony erosions. Also, it is important to distinguish these abnormalities from similar pathologies to prevent the use of inappropriate treatment We report the relevant clinical and radiological findings seen in three cases of posterior arch defect after trauma with review of pertinent literature.

• Imaging Science in Dentistry
• /
• v.36 no.4
• /
• pp.227-231
• /
• 2006

Leiomyosarcoma of the oral cavity is a very rare tumor that is associated with aggressive clinical behavior and low survival. In this paper, we report a case of leiomyosarcoma presenting with a gingival exophytic mass that rapidly grew, causing facial asymmetry within 16 days, in a 9-year-old boy. After an excisional biopsy, microscopy revealed a spindle cell neoplasm that, on immunohistochemistry analysis, demonstrated reactivity for SMA. This established the diagnosis of leiomyosarcoma; subsequently, a marginal mandibulectomy and supraomohyoid neck dissection were performed.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.34 no.1
• /
• pp.76-80
• /
• 2012

Adenoid cystic carcinoma is a distinctive neoplasm of the salivary gland and is the most common malignant tumor of submandibular gland. Although adenoid cystic carcinoma grows slowly, it shows aggressive tendencies with the ability to invade peripheral nerves. This ability enables an adenoid cystic carcinoma to extend along the nerves and spread long distances, resulting in high incidence of distant metastasis and recurrence. Therefore, radical resection is the treatment of choice for this carcinoma. We performed partial mandibulectomy, neck dissection and immediate reconstruction using a radial forearm free flap on a 54 year-old man with adenoid cystic carcinoma on the right submandibular gland. And as an adjunctive therapy, chemotherapy with cisplatin and 5-fluorouracil was used. We report our case along with a literature review.

• Journal of Chest Surgery
• /
• v.28 no.12
• /
• pp.1155-1159
• /
• 1995

Differentiated thyroid carcinoma is a slow growing tumor with relative good prognosis. But locally advanced thyroid cancer with T4 or N1b is difficult to manage. Between June 1988 and April 1995, we resected 8 advanced thyroid cancers trans-sternally. All patients had direct mediastinal extension [T4 or mediastinal lymph node metastasis [N1b with airway obstruction or dysphagia. We operated all the patients by partial or total sternotomy for mediastinal dissection along with thyroidectomy and radical neck dissection. There were some acceptable morbidities but no operative mortality. Postoperative radioactive iodine therapy was followed without side effects. Follow-up survival period was between 11 months to 81 months with 2 late mortalities [17 month, 30 month . Although definite benefit for routine mediastinal dissection in thyroid cancer has not been established, in locally advanced cases impending airway obstruction or dysphagia who have questionable effect by radioactive iodine therapy alone, aggressive mediastinal mass dissection including lymph node metastasis has the significant role to prevent the patients from suffocation & dysphagia, and to enhance the effect of followed radioactive iodine tharapy.

• Imaging Science in Dentistry
• /
• v.38 no.4
• /
• pp.225-228
• /
• 2008

Rhabdomyosarcoma (RMS) is an aggressive and fast-growing malignant tumor. RMS predominantly arises in the head and neck of infancy and children. Metastasis is usually via the blood vessel. We report a case of a recurred RMS of the tongue base with the metastasis to multiple lymph nodes in a 37-year-old female. On the follow-up examination using advanced imaging modalities after surgical treatment of RMS, the lymph nodes should be carefully evaluated like in other malignancies, such as a carcinoma, showing frequent lymph node metastasis. (Korean J Oral Maxillofac Radiol 2008; 38 : 225-8)

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• v.46 no.4
• /
• pp.288-291
• /
• 2020

Angiosarcoma is a rare malignant mesenchymal tumor of vascular or lymphatic origin and represents less than 1% of all malignant tumors. Radiation therapy is a standard treatment in many head and neck cancer cases, but ionizing radiation is associated with radiation carcinogenesis including radiation-induced angiosarcoma. In this article, we report a rare case of radiation-induced angiosarcoma found in a 58-year-old female patient who was previously diagnosed with an odontogenic keratocyst and mucoepidermoid carcinoma.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.13 no.3
• /
• pp.332-337
• /
• 1991

Kimura's disease is a chronic inflammatory condition producing subcutaneous tumor-like nodules mainly head and neck regions. Elevated serum Ig E levels and peripheral blood eosinophilia are common. Kimura's disease represents and aberrant immune reaction to an as yet unknown stimulus. This case presented is 27 year old female whose chief complaint were painful swelling on Rt cheek and temporal area and diagnosed as Kimura's disease. We preformed surgical excision of the mass on Rt. cheek and temporal area and reconstructed with temporal flap and about 100 cc of free fat graft on the defect of Rt. cheek.

• Investigative Magnetic Resonance Imaging
• /
• v.23 no.4
• /
• pp.385-389
• /
• 2019

Schwannoma or neurilemmoma is a benign peripheral nerve sheath tumor that arises from Schwann cells. Approximately 25-45% of all schwannomas occur in the head and neck regions, and the intraoral presentation of these is only 1%. We report a rare case of a patient presenting tongue base schwannoma with characteristic imaging features on computed tomography and magnetic resonance imaging.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.12
• /
• pp.5243-5245
• /
• 2016

Background and Objective : Bone morphogenic protein-2 (BMP-2) plays an essential role in mesenchymal cell differentiation into osteoblasts، through many intracellular pathways which may also be active in tumors. Invasive oral squamous cell carcinomas account for more than 90% of head and neck malignancies in many cancer registries. They are classified into three types according to epithelial cell differentiation. The present study aimed to identify any relation between BMP-2 expression and tumor histology. Materials and methods: BMP-2 expression was compared immunohistochemically among 30 cases (19 male and 11 female, mean age 48 years) of oral squamous cell carcinoma, Division was into 3 groups (each containing 10 cases) according to the histological grade. Results: No significant correlation between BMP-2 expression and histological grade was observed. Changes in localization and cytoplasmic staining were also not apparent. Conclusion: From the results of this study BMP-2 does not appear to have any application as a prognostic marker for oral squamous cell carcinomas.