• Title/Summary/Keyword: Natural substances

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Antioxidant Activity and Anti-inflammatory Effects of Salix Koreensis Andersson Branches Extracts (버드나무(Salix Koreensis Andersson) 가지 추출물의 항산화 및 항염증 효과)

  • Kim, Mi-Hye
    • Journal of the Korean Society of Food Culture
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    • v.33 no.2
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    • pp.104-111
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    • 2018
  • This study aims to compare and analyze a willow tree (Salix Koreensis andersson) extract's antioxidant and anti-inflammatory activity by investigating its: total polyphenol, flavonoid content, SOD-like activity, DPPH vitality. the willow tree was induced with LPS to determine its active anti-inflammatory effects. as a result, the willow methanol extract showed a higher total polyphenol and flavonoid content than those of willow distilled water extract, but the willow distilled water extract showed a higher SOD than that of willow methanol extract. in its DPPH scavenging ability, the willow methanol extract's antioxidant activity was higher than that of the willow distilled water extract. the willow extract's measurements such as the production of NO, inflammatory cytokine ($TNF-{\alpha}$, IL-6 measurement) were significantly reduced as its concentration level went down. according to the research outcomes, when induced, he will extract's macrophage produces mediator-like substances such as NO and inflammatory cytokine that can be used to alleviate the inflammatory response. therefore, the willow tree proved to be a useful raw plant material for the products designed to combat inflammatory activities due to its natural antioxidant and anti-inflammatory response substances such as NO and cytokine.

A Study on the Long-term Operating plan of Ventilation System of Apartment House in terms of Energy Performance (공동주택 강제 환기 시스템의 건물에너지 측면에서의 장기적 운영 방안에 관한 연구)

  • Kim, Seung-Chul;Yoon, Jong-Ho;Baek, Nam-Choon;Shin, U-Cheul
    • 한국태양에너지학회:학술대회논문집
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    • 2011.11a
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    • pp.115-123
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    • 2011
  • Because buildings recently built have been highly insulated and highly airtight, it is impossible to emit toxic substances from interior finishing materials only by natural ventilation. Therefore, they cause indoor air pollution and it may threaten the user"s health such as atopic dermatitis, bronchial asthma and (allergic) rhinitis. Domestically, users spend indoors 80 percent of their time of a day. With the increased interest in indoor air quality, the introduction of forced ventilation system for new-built apartment buildings has been legislated. However, toxic substances from indoor are mostly below there commended standard approximately 23 months later. Thus, this study has assumed the status of the apartment buildings 23 months later through a simulation, regarded $CO_2$ as an exclusive indoor air pollution source. In the process of effectively eliminating the $CO_2$, this study has also been conducted on an operating plan that can provide superior performance from the energy side.

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A Study on the Spatial Characteristics of the Pharmacy and Worker's Satisfaction about Interior Design (약국의 공간 특성과 근무자 만족도 연구)

  • Ju, Su-Eun;Shin, Kyung-Joo
    • Korean Institute of Interior Design Journal
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    • v.15 no.2 s.55
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    • pp.37-47
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    • 2006
  • The purpose of this study was to provide basic data for better design of Pharmacy after introducing the new system of separation of dispensing from prescribing medicine. To analyze characteristics of interior design in pharmacy and to measure worker satisfaction, a survey was conducted with 255 workers who serve at any Pharmacies located in Busan, Korea. For data analysis, descriptive statistics, t-test, One-way ANOV A were performed with the SPSS Win program(Ver. 10.0). The major findings were as follows: 1) As a result of analyzing the role and functions of the pharmacist is to be classified into many items such as entrance, a waiting room, a dispensary, a medication & consultation area, a drug storage and a worker's room. 2) Natural substances should be used more widely instead of using chemical substances for the pharmacy interior design as finishing materials 3) Pharmacy worker's satisfaction with dispensary is specially low among the total satisfaction which is :slightly higher than the average. 4) The degree of satisfaction between pharmacy workers from different groups varied depending on work hours, and especially long time(over 10hrs) workers showed dissatisfaction. Pharmacy managers need to consider the option of expanding convenience facilities. 5) According to the satisfaction analysis for each pharmacy conditions, the group who worked in 30-pyeong spaces were most satisfied. Since the 30-pyeong space is most standardized space research should be conducted.

Comparison of TLC and GC-MS Method in the Analysis of Dye Extracted from Madder Plant (꼭두서니 추출염료에 대한 TLC와 GC-MS 분석법의 비교 연구)

  • ;S. Kay Obendorf
    • The Research Journal of the Costume Culture
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    • v.12 no.4
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    • pp.579-590
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    • 2004
  • This research was aimed to investigate and compare the effectiveness of TLC and GC-MS methods in the analysis of chromophoric substances extracted from madder plant. Alizarin and purpurin 0.3% solution were used as comparative standards; madder extraction was prepared by heating the solution of powdered madder at 80℃, pH 1.5, for 90 min. Best elution solvent for TLC in silica gel plate was toluene:ethyl acetate=9:1, which resulted in red and yellow spots from madder extraction each of which showed R/sub f/ values 0.32-0.43 and 0.07-0.11. Although the red spot in particular exhibited similar characteristics as standard purpurin in color, shape, and R/sub f/ values, the result was inconsistent throughout different TLC trials. GC-MS analysis showed only small amount of alizarin and no purpurin in the madder extraction. Other chromophoric substance such as 2-furancarboxaldehyde, 5-(hydroxymethyl)-, anthralin, and danthron were also detected in small amounts. The result indicated that TLC was less sensitive to detecting and identifying the natural dyestuff which is generally constituted with a number of similar but chemically different chromophoric substances.

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Prevention from Microbial Post-harvest Injury of Fruits and Vegetables by Using Grapefruit Seed Extract, a Natural Antimicrobial Agent -Isolation of antimicrobial substance from grapefruit seed extract- (천연항균제처리에 의한 과채류의 선도유지 및 병해방지에 관한 연구 -Grapefruit 종자추출물로 부터 활성물질의 분리를 중심으로-)

  • Jo, Seong-Hwan;Kim, Gi-Ok;Lee, Geun-Hoe
    • Food Science and Preservation
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    • v.1 no.1
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    • pp.1-7
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    • 1994
  • To investigate the effect of several bactericides and fungicides against fruit & vegetable decay grapefruit seed extract(GFSE) was tested in a dilution solution. GFSE was shown to be effective against decay and rind breakdown and to extend the shelf-life of fruits and vegetables during storage and tiansport. Antimicrobial efficiency of GFSE on a wide spectra of gram + & - bacteria, moulds and yeasts was demonstrated by the measurement of minimal inhibitory concentrations performed (Bacteria 10-500ppm, Fungi:250-1,000ppm, Yeasts:100-250ppm). GFSE was separated and extracted into water-soluble fraction, water-insoluble and non-dialyzed fraction to isolate the antimicrobial substances. The water-soluble fraction showed the most active antimicrobial effect. The antimicrobial substances were isolated by gas chromatography. As the result of the isolation using GC, Peak-D was found to be the antimicrobial compound in GFSE. The identification of the most antimicrobial substance was carried out by using GC-MS.

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The Need for Research on the Comparison of Sensory Characteristics between Cultured Meat Produced Using Scaffolds and Meat

  • Sol-Hee Lee;Jungseok Choi
    • Food Science of Animal Resources
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    • v.44 no.2
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    • pp.269-283
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    • 2024
  • Cultured meat is one of the research areas currently in the spotlight in the agricultural and livestock industry, and refers to cells obtained from livestock that are proliferated and differentiated and processed into edible meat. These cell-cultured meats are mainly studied at the lab-scale by culturing them in flasks, and for commercial use, they are produced using scaffolds that mimic cell supports. Scaffolds are broadly divided into fiber scaffolds, hydrogels, and micro-carrier beads, and these are classified according to processing methods and materials. In particular, a scaffold is essential for mass production, which allows it to have appearance, texture, and flavor characteristics similar to meat. Because cultured meat is cultured in a state where oxygen is blocked, it may be lighter in color or produce less flavor substances than edible meat, but these can be compensated for by adding natural substances to the scaffolds or improving fat adhesion. In addition, it has the advantage of being able to express the texture characteristics of the scaffolds that make up the meat in various ways depending on the materials and manufacturing methods of the scaffolds. As a result, to increase consumers' preference for cultured meat and its similarity to edible meat, it is believed that manufacturing scaffolds taking into account the characteristics of edible meat will serve as an important factor. Therefore, continued research and interest in scaffolds is believed to be necessary.

Study on the reduction of heterocyclic amines by marinated natural materials in pork belly

  • Hea Jin, Kang;Seung Yun, Lee;Da Young, Lee;Ji Hyeop, Kang;Jae Hyeon, Kim;Hyun Woo, Kim;Jae Won, Jeong;Dong Hoon, Oh;Sun Jin, Hur
    • Journal of Animal Science and Technology
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    • v.64 no.6
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    • pp.1245-1258
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    • 2022
  • This study was conducted to determine the effect of natural ingredient seasoning on the reduction of heterocyclic amine (HCA) production that may occur when pork belly is cooked at a very high temperature for a long time. Pork belly seasoned with natural ingredients, such as natural spices, blackcurrant, and gochujang, was cooked using the most common cooking methods, such as boiling, pan fry, and barbecue. HCAs in pork belly were extracted through solid-phase extraction and analyzed via high-performance liquid chromatography. For short-term toxicity, a mouse model was used to analyze weight, feed intake, organ weight, and length; hematology and serology analysis were also performed. Results revealed that HCAs formed only when heating was performed at a very high temperature for a long time, not under general cooking conditions. Although the toxicity levels were not dangerous, the method showing the relatively highest toxicity among various cooking methods was barbecue, and the natural material with the highest toxicity reduction effect was blackcurrant. Furthermore, seasoning pork belly with natural materials containing a large amount of antioxidants, such as vitamin C, can reduce the production of toxic substances, such as HCAs, even if pork belly is heated to high temperatures.

On the utrophication in the Lake Changja (장자못의 부영양화에 관하여)

  • Lee, Kyung;Uhm, Kyu-Baek;Kwon, Young-Myung
    • Journal of Plant Biology
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    • v.18 no.3
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    • pp.135-138
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    • 1975
  • The process of eutrophication was studied in the lake Changja from November in 1974 to May in 1975. The stratification of water temperature was going to be formed in April and the content of dissolved oxygen varied a little but it was almost zero from January. Total phosphorus was increased very rapidly in February but total nitrogen and carbohydrate-like substances were increased a little during the experimental period. The amount of chlorophyll-$\alpha$ varied from 127mg/$m^2$ to 717 mg/$m^2$ with maximum value occuring in January. This phenomenon was an evidence that chlorophyll-$m^2$ and total phosphorus were correlated each other. The numbers of colony of the coliform bacteria in point A was 10 times more than in point B. In conclcesions, the lake Changja is a very eutrophic and the ecological equilibrium of the lake can not be recovered as far as origin of pollution is erased out.

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Effects of Indomethacin on Development and Hatching of Mouse Embryo (Indomethacin이 생쥐 착상전 배아의 발생 및 부화에 미치는 영향)

  • Cheon, Yong-Pil;Gye, Myung-Chan;Kim, Chung-Hoon;Kim, Moon-Kyoo
    • Clinical and Experimental Reproductive Medicine
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    • v.24 no.1
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    • pp.35-42
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    • 1997
  • The present study was designed to define the role of prostaglandin in the development and hatching of mouse embryo. The effects of indomethacin, an inhibitor of prostaglandin synthesis, on the development and hatching of morula and blastocyst were examined. In early morula stage, embryos were degenerated significantly at 100 ${\mu}M$ and 200 ${\mu}M$ indomethacin. However, the viability of embryos was not influenced by concentration in any other embryonic stages. In all embryonic stages, the hatching was suppressed with concentration dependent manner, but expansion was not suppressed. Particularly, in 84h embryos post hCG injection, the hatching was suppressed significantly compared with post hCG 72h or 96h embryos. When embryos were treated with 100 ${\mu}M$ indomethacin for a specific time (12h) in according to the development stage, the hatching was suppressed all groups. These suppressional effect was decreased as embryonic development stage was progressed. However, the expansion was not affected in all treatment group. This study suggests that hatching-related metabolic substances are synthesized from morula stage and intraembryonic signaling mediated prostaglandin was important for development and hatching of mouse embryo.

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Solvolysis Reaction Kinetics, Rates and Mechanism for Phenyl N-Phenyl Phosphoramidochloridate

  • Choi, Hojune;Yang, Kiyull;Koh, Han Joong;Koo, In Sun
    • Bulletin of the Korean Chemical Society
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    • v.35 no.8
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    • pp.2465-2470
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    • 2014
  • The rate constants of solvolysis of phenyl N-phenyl phosphoramidochloridate (PhNHPO(Cl)OPh, Target Compound-TC1) have been determined by a conductivity method. The solvolysis rate constants of TC1 are well correlated with the extended Grunwald-Winstein equation, using the $N_T$ solvent nucleophilicity scale and YCl solvent ionizing scale, and sensitivity values of $0.85{\pm}0.14$ and $0.53{\pm}0.04$ for l and m, respectively. These l and m values were similar to those obtained previously for the complex chemical substances dimethyl thiophosphorochloridate; N,N,N',N'-tetramethyldiamidophosphorochloridate; 2-phenyl-2-ketoethyl tosylate; diphenyl thiophosphinyl chloride; and 9-fluorenyl chloroformate. As with the five previously studied solvolyses, an $S_N2$ pathway is proposed for the solvolyses of TC1. For four representative solvents, the rate constants were measured at several temperatures, and activation parameters (${\Delta}H^{\neq}$ and ${\Delta}S^{\neq}$) were estimated. These activation parameters are also in line with the values expected for an $S_N2$ reaction.