• 대한예방한의학회지
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• 제17권2호
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• pp.179-187
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• 2013

Objectives : In many cases, patient's symptoms have been recorded on EMR in natural language instead of medical terminologies. It is possible to build a database by analyzing the symptoms of Korean Medicine(KM) that indicates patient's symptoms in natural language. Using the database, when doctors record patient's symptoms on EMR in natural language, conversely it'll be also possible to extract the symptoms of KM from those natural language. The database will enhance the value of EMR as a medical data. Methods : In this study, we aimed to make data structure of the terminologies that represent the symptoms of KM. The data structure is combinations of smallest unit in natural language. We made the database by analyzing morpheme of the natural language to express the symptoms of KM. Results & Conclusions : By classifying the natural language in 15 features, we made the structure of concept and the data available for morphological analysis.

• Molecules and Cells
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• 제45권7호
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• pp.495-501
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• 2022

Leucine dehydrogenase (LDH, EC 1.4.1.9) catalyzes the reversible deamination of branched-chain L-amino acids to their corresponding keto acids using NAD⁺ as a cofactor. LDH generally adopts an octameric structure with D4 symmetry, generating a molecular mass of approximately 400 kDa. Here, the crystal structure of the LDH from Pseudomonas aeruginosa (Pa-LDH) was determined at 2.5 Å resolution. Interestingly, the crystal structure shows that the enzyme exists as a dimer with C2 symmetry in a crystal lattice. The dimeric structure was also observed in solution using multiangle light scattering coupled with size-exclusion chromatography. The enzyme assay revealed that the specific activity was maximal at 60℃ and pH 8.5. The kinetic parameters for three different amino acid and the cofactor (NAD⁺) were determined. The crystal structure represents that the subunit has more compact structure than homologs' structure. In addition, the crystal structure along with sequence alignments indicates a set of non-conserved arginine residues which are important in stability. Subsequent mutation analysis for those residues revealed that the enzyme activity reduced to one third of the wild type. These results provide structural and biochemical insights for its future studies on its application for industrial purposes.

• 대한기계학회논문집B
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• 제27권2호
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• pp.251-258
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• 2003

Natural gas hydrates typically contain 85 wt.% water and 15 wt.% natural gas, and commonly belongs to cubic structure I and II. When referred to standard conditions, 1㎥ solid hydrates contain up to 172N㎥ of methane gas, depending on the pressure and temperature of production. Such large volumes make natural gas hydrates can be used to store and transport natural gas. So, the tests were performed on the formation of natural gas hydrate is governed by the pressure, temperature, gas composition etc. The results show that the formation pressure of structure II is lower about 65% and the solubility is higher about 3 times than that of structure I.

• 한국지진공학회:학술대회논문집
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• 한국지진공학회 1999년도 추계 학술발표회 논문집 Proceedings of EESK Conference-Fall
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• pp.170-177
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• 1999

The natural period calculation equations specified in the current building code are empirical formulas that depend on height and material type of the structure. Building with the upper wall and lower frame type is a unique structure which composed of two different structural system This type of structure needs either the deep transfer girder or the thick transfer plate that brings the sudden change of stiffness and mass. Therefore the natural period equations recommended by the current code can not be applied directly. In this study the natural period of building with typical plan obtained by dynamci analysis is compared with that of various codes. Ad approximate estimation equation for the natural period of building with the upper wall and lower frame type obtained by regression analysis is recommended. by the current code can not be applied directly. In this study the natural period of building with typical plan obtained by dynamic analysis is compared with that of various codes, And approximate estimation equation for the natural period of building with the upper wall and lower frame type obtained by regression analysis is recommended.

• Natural Product Sciences
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• 제24권2호
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• pp.115-118
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• 2018

Herein, we reported the phytochemical investigation of whole thallus Sumatran lichen, Stereocaulon graminosum Schaer, and isolated a mono aromatic compound, ethyl haematommate (1). The structure of compound 1 have been established based on spectroscopic data and confirmed by single crystal X-ray structure analysis.

• 한국공간구조학회논문집
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• 제15권2호
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• pp.113-120
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• 2015

This study investigate the dynamic response changes of rib dome structure according to property changes of Substructure. Eigenvalue analysis is conducted in first natural frequency of rib dome versus substructure and searched in the dominant mode of horizontal and vertical direction. Resonance frequency by each first natural frequency of the rib dome structure, substructure and total structure is applied for a seismic wave. That is analyzed about maximum displacement response ratio and maximum acceleration response ratio.

• Computational Structural Engineering : An International Journal
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• 제2권1호
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• pp.25-32
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• 2002

Natural draught cooling towers often develop visible crack structures as consequences of progressive damage processes over their life-time. The aim of this paper is a numerical demonstration of the progressive damage process of cooling towers, representatively for the reinforced concrete structures, in order to improve the durability and extend the life-time of structures subjected to such damage processes. For the analyses, the applied material model for reinforced concrete will be briefly introduced. An existing natural draught cooling tower with a pronounced crack structure, in which this crack structure indicates the typical damage pattern of large cooling towers will be numerically simulated. The change of dynamical behavior of the structure with regard to natural frequencies, reflecting the global damage process due to the degrading stiffness of the structure in dependence of the load type and intensity, will be presented and discussed.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회B
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• pp.3497-3500
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• 2007

The internal structure is subjected to dynamic analysis due to the structural integrity. The internal structure shall be installed in the vertical hole call IR1 of reactor core. In order to verify the deflection of the internal structure, the mode and response spectrum analysis of the internal structure was performed. The natural frequency of the internal structure is 11.6 Hz(mode 1 and 2) and deflections of the internal structure are less than values of allowable design (3.2 mm).

• Bulletin of the Korean Chemical Society
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• 제29권5호
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• pp.1003-1006
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• 2008

Highly efficient syntheses of cylindol A (1) and the proposed structure of cylindol B (2) have been accomplished using common synthetic transformations from symmetrical starting materials 7 and 11, respectively. The latter synthesis revealed that the proposed structure of the natural cylindol B was assigned incorrectly. Isomers of 2 such as 15 and 16 were synthesized as a possible candidate of the natural cylindol B. However, their spectral data also did not match that of the natural cylindol B. Therefore, the structure of the natural cylindol B is yet to be resolved.

• 한국공간구조학회논문집
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• 제9권1호
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• pp.79-85
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• 2009

최근의 대공간구조물은 장스팬화 됨은 물론이고 경량화되면서 면외 방향의 강성이 매우 작아지고 있다. 이로 인하여 공력불안정 진동의 발생 여부는 물론이고 연성구조물의 판단시에도 고유진동수의 정확한 산정이 필요하다. 그러나 국내외 대공간구조물의 고유진동수 제안식에 대한 연구는 매우 미흡한 실정이다. 따라서 국내 7개 공간구조물의 고유치해석에서 얻은 근사식을 일본건축학회 고유치해석에 근거한 2가지 제안식과 일본의 28개 공간구조물의 계측치에서 얻은 고유진동수 근사식을 비교하였다. 지붕의 고유진동수는 스팬이 증가함에 따라서 작아지는 경향을 확인하였다. 국내의 고유진동수 값은 전반적으로 일본의 공간구조물의 해석과 계측에 근거한 고유진동수보다 동일한 스팬에서 작은 경향을 보임을 알 수 있었다. 따라서 국내 공간구조물의 지붕은 일본의 경우보다 비교적 연성구조물인 것을 확인할 수 있다.