• Title/Summary/Keyword: Natural product

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Phytochemical Constituents of Artemisia sylvatica Max (그늘쑥의 식물화학적 성분)

  • Moon, Hyung-In;Kwon, Hak-Cheol;Zee, Ok-Pyo;Lee, Kang-Ro
    • Korean Journal of Pharmacognosy
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    • v.30 no.1
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    • pp.87-91
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    • 1999
  • Two carotenoids and four flavonoids were isolated from the whole plant of Artemisia sylvatica Max. Their structures were identified as ${\beta}-carotene$, lutein, luteolin, rutin, $pectolinarigenin-7-O-{\beta}-glucopyranoside$ and luteolin-7-O-neohesperidoside on the basis of spectroscopic means.

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Flavonoids with anticomplement activity from Persicaria lapathifolia

  • Park, Si-Hyung;Oh, Sei-Ryang;Kim, Young-Soo;Lee, Hyeong-Kyu
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1998.11a
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    • pp.186-186
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    • 1998
  • Persicaria lapathifolia Gray (Polygonaceae) is a common weed in Korea. This plant and other Persicaria species including P. orientale and P. pubescens have been used as an analgesic and stomachic as well as for the treatment of rheumatoid arthritis and malaria. During the screening program of plant extracts, MeOH extract of P. scabrum showed anticomplement activity and the MeOH extract was partitioned with hexane, chloroform, ethyl acetate, and buthanol. EtOAc fraction showed strong activity and activity guided separation yielded eight flavonoids. Two known galloylated and a novel ferulloylated flavonoid glycosides showed strong anticomplement activity. Other flavonoid glycosides, kaempferol 3-O-${\alpha}$-$\sub$L/-arabinopyranoside, kaempferol 3-O-${\beta}$-$\sub$D/-glucopyranoside, kaempferol 3-O-${\beta}$-$\sub$D/-galactopyranoside, quercetin 3-O-${\alpha}$-$\sub$L/-arabinopyranoside, quercetin 3-O-${\beta}$-$\sub$D/-glucopyranoside, quercetin O-${\beta}$-$\sub$D/-galactopyranoside did not showed anicomplement activity.

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Phytochemical Constituents of Sagittaria trifolia (벗풀의 식물화학적 성분)

  • Kim, Ki-Tack;Moon, Hyung-In;Lee, Kang-Ro;Zee, Ok-Pyo
    • YAKHAK HOEJI
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    • v.42 no.2
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    • pp.140-143
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    • 1998
  • From the methanol extract of the whole part of Sagittaria trifolia ergosterol peroxide, icariside D2. Thalictoside and 4-nitrophenyl $\{beta}$-D-glucopyranoside wer e isolated and their structures were identified by the physico-chemical and spectral data. This is the first report of these compounds from S. trifolia.

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Phytochemical and therapeutic potentials of Morinda tinctoria Roxb. (Indian mulberry)

  • Sahoo, Atish K;Narayanan, Nisha;Kumar, N Satheesh;Rajan, S;Mukherjee, Pulok K
    • Advances in Traditional Medicine
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    • v.9 no.2
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    • pp.101-105
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    • 2009
  • Morinda tinctoria Roxb. (Family: Rubiaceae) is commonly known as Indian mulberry or Aal in India. This plant is very well known for its therapeutic benefit in Indian systems of medicine including Ayurveda and Siddha and in other forms of traditional Medicine worldwide for the treatment of several ailments. Almost all parts of this plant have been explored for its medicinal uses. Several reports on the phytochemical and therapeutic benefits of this plant have been reported. In this article an attempt has been made to review the traditional uses, phytochemical profiles and therapeutic potentials of Indian mulberry.

Variation of Diarylheptanoid from Alnus sibirica Fitch. Ex Turcz. Processed Enzymatic Hydrolysis (효소분해에 따른 물오리나무 Diarylheptanoid 화합물의 함량 변화)

  • Wang, Hye Soo;YIN, JUN;Hwang, In Hyeok;Lee, Min Won
    • Korean Journal of Pharmacognosy
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    • v.49 no.4
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    • pp.336-340
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    • 2018
  • Alnus sibirica Fisch. ex Turcz.(AS) geographically distributes in Korea, Japan, Northeast China and Russia. The bark of Alnus species have been used as traditional medicine for the treatment of allergic skin diseases. The content evaluation of compounds which were isolated from the barks of A. sibirica processed enzymatic hydrolysis(EAS); hirsutanonol(1), 5-O-methylhirsutanonol(2), rubranol(3), hirsutenone(4) and muricarpone B(5) was conducted using HPLC. Consequently, in EAS, the content of glycoside was decreased considerably. But the aglycones(1, 3 and 4) were increased highly and 2, 5 were formed newly.

Effect of the Extract of Cultured Ginseng Roots on Hyperlipidemia in Rats

  • Yi, Eun-Jeong;Hailin, Zhao;Li, Da-Wei;Paek, Kee-Yeoup;Kim, Jong-Hoon;Kim, Yeong-Shik
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.263.1-263.1
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    • 2002
  • We have investigated the effect of MeOH extract of cultured ginseng roots on hyperlipidemic rats induced by fat-rich diet. We also analyzed and compared ginsenosides of cultured ginsengs by HPLC. After oral administration of the extract to hyperlipidemic rats for four weeks, the variables including body weight, cholesterol, HDL, LDL, and triglyceride levels in serum were measured. One of the cultured ginseng roots (CBN3) decreased cholesterol and LDL -cholesterol and increased HDL-cholesterol levels in serum.. (omitted)

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Current status of natural product industry and its commercial application to health functional foods

  • Park, Jong Dae
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2018.10a
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    • pp.21-21
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    • 2018
  • Natural product substances have historically served as the most significant also be prepared by source of new leads for pharmaceutical development. They can chemical synthesis(both semisynthesis and total synthesis) and have played a important role in the field of organic chemistry by providing synthetic targets. Rcently, they have also been extended for commercial purpose to refer to medicinal products, health functional foods, dietary supplements and cosmetics from natural sources. A large number of currently prescribed drugs have been either directly derived from or inspired by natural products. However, with the advent of robotics, bioinformatics, high throughput screening(HTS), molecular biology-biotechnology, combinatorial chemistry, in silico(molecular modeling) and other methodologies, the pharmaceutical industry has largely moved away from plant derived natural products as a source for leads and prospective drug candidates. The strategy for natural prduct industry is now changing from drug approaches to health foods by identifying effective natural products as preparations. In Korea, a lot of development of natural product based drugs have been done, but very few on health functional foods. The concept of natural product based health foods is not active components as lead compounds but standardized extracts or preparation mixed with other medicinal plants. The representative material has been recently known to be a standardized ginseng extract "Ginsana G 115" developed by Swiss Pharmaton company. The purpose of this presentation is to underline how natural products research continues to make significant contributions in the domain of discovery and development of new health functional foods. It is proposed to present the development of high value added health food or health functional foods through scientific investigation on efficacy and standardization of new materials form natural products.

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