• Title/Summary/Keyword: Natural product

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A Pyridyl Alkaloid and Benzoic Acid Derivatives from the Rhizomes of Anemarrhena asphodeloides

  • Youn, Ui-Joung;Lee, Yoo-Jin;Jeon, Ha-Rim;Shin, Hyun-Ji;Son, Young-Min;Nam, Joo-Won;Han, Ah-Reum;Seo, Eun-Kyoung
    • Natural Product Sciences
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    • v.16 no.4
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    • pp.203-206
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    • 2010
  • A pyridyl alkaloid, 3-pyridylcarbinol (1) and benzoic acid derivatives, 4-hydroxy benzoic acid (2), 4-hydroxyactophenone (3), vanilic acid (4), and benzoic acid (5) were isolated from the rhizomes of Anemarrhena asphodeloides on the basis of spectroscopic and physicochemical analyses including 1D- and 2D- NMR techniques as well as by comparison of their data with the published values. Compounds 1 - 5 were isolated for the first time from this plant source.

Perceived Risks and Benefits to Natural Dyeing Product -The Role of Product Knowledge- (천연염색 의류제품에 대한 지각된 위험과 혜택 -천연염색 제품지식에 따른 차이-)

  • Hong, Hee-Sook;Hong, Byung-Sook
    • Journal of the Korean Society of Clothing and Textiles
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    • v.32 no.9
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    • pp.1343-1355
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    • 2008
  • This study examined the influences of product knowledge(subject knowledge, purchase experience and information search) on perceived risks and benefits to natural dyeing product. Data were collected from a total of 213 Korean females ranging from 20 to 50 years old who know natural dyeing product through online survey. There were significant differences between(or among) groups with different levels of subject knowledge, purchase experience and information search in several types of perceived risks and benefits to natural dyeing product. Consumers with high knowledge of natural dyeing product perceived several types of risks lower than consumers with low knowledge but they perceived several types of benefits higher than consumers with low knowledge.

Mucin modifies microbial composition and improves metabolic functional potential of a synthetic gut microbial ecosystem

  • Mabwi, Humphrey A.;Komba, Erick V.G.;Mwaikono, Kilaza Samson;Hitayezu, Emmanuel;Mauliasari, Intan Rizki;Jin, Jong Beom;Pan, Cheol-Ho;Cha, Kwang Hyun
    • Journal of Applied Biological Chemistry
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    • v.65 no.1
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    • pp.63-74
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    • 2022
  • Microbial dysbiosis in the gut is associated with human diseases, and variations in mucus alter gut microbiota. Therefore, we explored the effects of mucin on the gut microbiota using a community of 19 synthetic gut microbial species. Cultivation of these species in modified Gifu anaerobic medium (GAM) supplemented with mucin before synthetic community assembly facilitated substantial growth of the Bacteroides, Akkermansia, and Clostridium genera. The results of 16S rRNA microbial relative abundance profiling revealed more of the beneficial microbes Collinsella, Bifidobacterium, Ruminococcus, and Lactobacillus. This increased acetate levels in the community cultivated with, rather than without (control), mucin. We identified differences in predicted cell function and metabolism between microbes cultivated in GAM with and without mucin. Mucin not only changed the composition of the gut microbial community, but also modulated metabolic functions, indicating that it could help to modulate microbial changes associated with human diseases.

An Analysis of Natural Motion for Product Design : Refrigerator Half Guard Installation Part Design (자연스러운 동작 분석을 통한 냉장고 Half Guard 조립체의 인간공학적 개선)

  • Park, Jang-Woon;Kim, Su-Jin;You, Hee-Cheon
    • Journal of Korean Institute of Industrial Engineers
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    • v.37 no.1
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    • pp.10-18
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    • 2011
  • Ergonomic product design considering users' natural use motion is of importance to improve the usability and satisfaction of a product. A five-step process of product design was developed in the present study by measuring and analyzing users' natural product-use motion with a motion capture system. The developed process was applied to ergonomic design improvement of a half guard installation part of refrigerator; new guard designs (diagonal and arc shape) were developed with the process and evaluated in terms of validity during the development as two measures (task satisfaction and similarity of natural motion). According to the evaluation result, the satisfaction at putting in- and out-task of new guard designs ($6.3{\pm}0.5$ points) was significantly higher than that of existing guard designs ($3.3{\pm}1.0$ points); the difference between natural motion and product-use motion in new guard designs ($1.0{\pm}0.3cm$) was significantly less than that of existing guard designs ($2.0{\pm}0.2cm$). The proposed process of natural motion analysis and product design is applicable to ergonomic product design and evaluation.

Cancer Chemopreventive Effects of Korean Seaweed Extracts

  • Lee, Saet-Byoul;Lee, Joo-Young;Song, Dae-Geun;Pan, Cheol-Ho;Nho, Chu-Won;Kim, Min-Cheol;Lee, Eun-Ha;Jung, Sang-Hoon;Kim, Hyung-Seop;Kim, Yeong-Shik;Um, Byung-Hun
    • Food Science and Biotechnology
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    • v.17 no.3
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    • pp.613-622
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    • 2008
  • Cancer chemopreventive effects can be exerted through the induction of phase II detoxification enzymes and the inhibition of inflammatory responses. In this study, the cancer chemopreventive effects and anti-inflammatory responses of 30 seaweed extracts were examined. The extracts of Dictyota coriacea and Cutleria cylindrica exhibited the high chemoprevention index, having 4.36 and 4.66, respectively. They also activated antioxidant response element at $100\;{\mu}g/mL$ by about 3-fold while did not activate xenobiotic response element. Seven seaweed extracts, Ishige okamurae, Desmarestia ligulata, Desmarestia viridis, Dictyopteris divaricata, D. coriacea, Sargassum horneri, and Sargassum yezoense, showed significant inhibition on nitric oxide (NO) and prostaglandin $E_2$ ($PGE_2$) production in a dose-dependant manner in $5-20\;{\mu}g/mL$. These seaweed extracts could be used as food materials for cancer chemoprevention. D. coriacea could contain potential chemopreventive agents not only that regulate genes via an ARE-dependent mechanism but also prevent the inflammation through inhibition of NO and $PGE_2$ production.

Quantitative Analysis and Validation of Hirsutenone and Muricarpone B from Fermented Alnus sibirica

  • YIN, Jun;YOON, Ki Hoon;YOON, Seong Hye;AHN, Hye Shin;LEE, Min Won
    • Natural Product Sciences
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    • v.23 no.2
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    • pp.146-150
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    • 2017
  • Alnus sibirica (AS) geographically distributes in Korea, Japan, Northeast China and Russia. The bark of this plant had been used for antipyretic, expectorant, anti-phlogistic, antitussive, anti-asthmatic and as a health tea for alcoholism. Recently, we studied various biological activities of AS and the isolated diarylheptanoid. In present study, we conducted fermentation of AS (FAS) and isolated two diarylheptanoid (hirsutenone and muricarpone B). Moreover, we established the validation and contents determinations of the two compounds by HPLC on FAS.