• 제목/요약/키워드: Natural population

검색결과 1,573건 처리시간 0.029초

Variant Alleles in XRCC1 Arg194Trp and Arg399Gln Polymorphisms Increase Risk of Gastrointestinal Cancer in Sabah, North Borneo

  • Halim, Noor Hanis Abu;Chong, Eric Tzyy Jiann;Goh, Lucky Poh Wah;Chuah, Jitt Aun;See, Edwin Un Hean;Chua, Kek Heng;Lee, Ping-Chin
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권4호
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    • pp.1925-1931
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    • 2016
  • Background: The XRCC1 protein facilitates various DNA repair pathways; single-nucleotide polymorphisms (SNPs) in this gene are associated with a risk of gastrointestinal cancer (GIC) with inconsistent results, but no data have been previously reported for the Sabah, North Borneo, population. We accordingly investigated the XRCC1 Arg194Trp and Arg399Gln SNPs in terms of GIC risk in Sabah. Materials and Methods: We performed genotyping for both SNPs for 250 GIC patients and 572 healthy volunteers using a polymerase chain reaction-restriction fragment length polymorphism approach. We validated heterozygosity and homozygosity for both SNPs using direct sequencing. Results: The presence of a variant 194Trp allele in the Arg194Trp SNP was significantly associated with a higher risk of GIC, especially with gastric and colorectal cancers. We additionally found that the variant 399Gln allele in Arg399Gln SNP was associated with a greater risk of developing gastric cancer. Our combined analysis revealed that inheritance of variant alleles in both SNPs increased the GIC risk in Sabah population. Based on our etiological analysis, we found that subjects ${\geq}50years$ and males who carrying the variant 194Trp allele, and Bajau subjects carrying the 399Gln allele had a significantly increased risk of GIC. Conclusions: Our findings suggest that inheritance of variant alleles in XRCC1 Arg194Trp and Arg399Gln SNPs may act as biomarkers for the early detection of GIC, especially for gastric and colorectal cancers in the Sabah population.

제7차 초등학교 교육과정 교과서의 환경 관련 내용 분석 (The Analysis of Contents Related to Environmental Education in the Elementary School Textbooks of 7th Korea National Curriculum)

  • 최영분;노경임;민병미
    • 한국환경교육학회지:환경교육
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    • 제15권1호
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    • pp.115-124
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    • 2002
  • The purpose of this research is to analyze the contents related to environmental education(EE) in the elementary school textbooks for the following areas: well-balanced EE, and development of EE curriculum/teachers' guide in elementary school level. For the purpose of this analysis, elementary school teachers, education administrators and EE specialists were involved. Eleven content areas of EE, namely: natural environment, artificial environment, population, industrialization, natural resources, pollution, environmental conservation, environment sanitation, environment ethics, environmentally sound and sustainable development(ESSD), and daily li(e as a consumer, were analyzed. The results of the analysis are as follows: 1. There are total 1,140 contents related to EE in the elementary school textbooks of 7th Korea National Curriculum. 2. The textbooks of grade 6 contain the most number of EE contents, while the least number is in the textbooks of grade 3. 3. The subject that includes EE contents equally in its textbooks is social studies, and the subjects that relate a lot to EE are Korean language, science, and social studies respectively. 4. The content areas that are included a lot in textbooks are' natural environment', 'pollution', and' environmental conservation' respectively, while the contents of 'population','industrialization', 'ESSD' are included to a lesser degree. The content area most frequently mentioned in the textbooks is 'pollution', and the number of the contents are increasing along with the grade level. 5. Generally, the content areas of 'population', 'industrialization', and 'natural resources' are reflected in the textbooks to a lesser degree than others. 'Industrialization' is not included in the textbooks of grade 2, while 'population' is not included in ones of grade 4. According to the result, more concern about balanced EE in content areas is needed at the elementary school level. Similar studies tot K and secondary school levels are needed. The developmental study of EE guide book and teacher training for teaching EE using the book are also recommended.

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Population Structure and Regeneration Status of Cyathea gigantea (Wallich ex Hook. f.) Holttum, a Tree Fern in Arunachal Pradesh, India

  • Paul, Ashish;Bhattacharjee, Sonal;Choudhury, Baharul Islam;Khan, Mohamed Latif
    • Journal of Forest and Environmental Science
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    • 제31권3호
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    • pp.164-176
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    • 2015
  • Cyathea gigantea is a tree fern distributed throughout humid tropical regions of northeast India and other parts of the country. However, wild populations of this species are largely affected by various natural and anthropogenic activities. Therefore, an attempt was made to study the population structure and regeneration status of C. gigantea in and around greater Itanagar area of Papum Pare district, Arunachal Pradesh. Altogether 45 patches, ranging from 19.63 to $260m^2$ of area, were randomly sampled to study population structure and regeneration status of the species. Population study showed highest number of youngs in the height class of 0.50-0.75 m while, immatures were recorded highest in the height class of 2.0 to 2.5 m. Majority of the matures belonged to 6-9 m height class while it was recorded maximum in the diameter class of 10-15 cm. Average density of C. gigantea was $0.07individuals\;ha^{-1}$ which varied greatly among different patches with a range of 2 to 14. Significant correlations were found between patch size and density of youngs, immatures, matures and total density. Maximum concentration of youngs was observed in patch size $60-140m^2$, while for immatures, it was highest in patch size $20-160m^2$. Similarly, highest concentration of matures was observed in patch size $20-80m^2$ and $80-180m^2$. Population structure of the total population exhibited inverted pyramid shaped distribution. Population structure consisting of youngs, immatures, matures showed that around 60% patches lack of regenerating individuals which depict very poor natural regeneration of the species. Effective conservation strategies are therefore to be formulated to save C. gigantea from the threat of extinction in near future.

Morphological and biochemical differences in three Undaria pinnatifida populations in Korea

  • Park, Kwang-Jae;Kim, Bo-Yeon;Park, Seo-Kyoung;Lee, Jong-Hwa;Kim, Young-Sik;Choi, Han-Gil;Nam, Ki-Wan
    • ALGAE
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    • 제27권3호
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    • pp.189-196
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    • 2012
  • Twelve morphological characters and the biochemical composition of Undaria pinnatifida f. distans sporophytes growing on the rocky shores of Jindo and Wando and on cultivation ropes in Kijang were measured to determine whether each population could be characterized by morphological features and biochemical composition. The goal of this study was to compare phenotypic variations between populations as they relate to environmental conditions. The sporophytes of the Kijang population were two times longer and 19 times heavier than those at Jindo. Sporophylls of the Jindo U. pinnatifida population were significantly smaller in length, width, frill number, and weight than those at Wando and Kijang. Kijang Undaria plants showed the highest contents of total protein, crude fiber, total amino acids, the amount of essential amino acids, the proportion of total unsaturated fatty acids, and eicosapentaenoic acid. However, the Jindo population showed the greatest content of carbohydrates, lipids, and minerals (Zn and Ca) of the three U. pinnatifida populations. In particular, Zn content of Jindo plants was 30 times greater than that of Kijang plants. Thus, the proximate composition, mineral composition, amino acids, and fatty acids of Undaria pinnatifida plants were distinguishable among the three representative Undaria populations evaluated. These results suggest that morphological and biochemical differences of the three U. pinnatifida populations can be attributed to differences in environmental conditions of their habitats.

Population structure and regeneration of Zanthoxylum armatum DC. in Salyan, Nepal

  • Phuyal, Nirmala;Jha, Pramod Kumar;Raturi, Pankaj Prasad;Rajbhandary, Sangeeta
    • Journal of Ecology and Environment
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    • 제46권2호
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    • pp.111-125
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    • 2022
  • Background: Zanthoxylum armatum is one of the 30 prioritized medicinal plants for economic development of Nepal with a high trade value. Understanding the ecology of individual species is important for conservation and cultivation purposes. However, relation of ecological factors on the distribution and populations of Z. armatum in Nepal remain unknown. To address this knowledge gap, an attempt has been made to study the population structure, distribution, and regeneration potentiality of Z. armatum. Vegetation sampling was conducted at six different localities of Salyan district along the elevation range of 1,000 m to 2,000 m. Results: Altogether 50 plant species belonging to 44 genera under 34 families were found to be associated with Z. armatum. Significantly higher species richness was found at Rim (1,400-1,700 m) and Chhatreshwori (1,800-2,000 m) and lower at Kupinde (1,600-1,800 m). The highest population density of Z. armatum was at Kupinde (1,600-1,800 m) with a total of 1,100 individuals/ha. and the lowest at Chhatreshwori (1,800-2,000 m) with 740 individuals/ha. Based on the A/F value (Whitford index), it can be said that Z. armatum has random distribution in the study area. The plants were categorized into seedlings, saplings and adults based on plant height and the status of natural regeneration category determined. The regeneration potentiality of Z. armatum in the study area was fair with the average seedlings and saplings densities of 150 and 100 individuals/ha. Respectively. A Shannon-Weinner index mean value of 2.8 was obtained suggesting high species diversity in the study area. Conclusions: The natural distribution and regeneration of Z. armatum is being affected in the recent years due to anthropogenic disturbances. Increasing market demand and unsustainable harvesting procedures are posing serious threat to Z. armatum. Thus, effective conservation and management initiatives are most important for conserving the natural population of Z. armatum in the study area.

유전자 알고리듬을 이용한 동역학적 구조물의 최적설계 (Optimal Design of Dynamic System Using a Genetic Algorithm(GA))

  • 황상문;성활경
    • 한국정밀공학회지
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    • 제16권1호통권94호
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    • pp.116-124
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    • 1999
  • In most conventional design optimization of dynamic system, design sensitivities are utilized. However, design sensitivities based optimization method has numbers of drawback. First, computing design sensitivities for dynamic system is mathematically difficult, and almost impossible for many complex problems as well. Second, local optimum is obtained. On the other hand, Genetic Algorithm is the search technique based on the performance of system, not on the design sensitivities. It is the search algorithm based on the mechanics of natural selection and natural genetics. GA search, differing from conventional search techniques, starts with an initial set of random solutions called a population. Each individual in the population is called a chromosome, representing a solution to the problem at hand. The chromosomes evolve through successive iterations, called generations. As the generation is repeated, the fitness values of chromosomes were maximized, and design parameters converge to the optimal. In this study, Genetic Algorithm is applied to the actual dynamic optimization problems, to determine the optimal design parameters of the dynamic system.

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Impact of Surface Fire on the Dynamics of$N_2$- Fixing and P - Solubilizing Microbial Population in Natural Grassland Soils, Southern India

  • Manian, S.;S. Paulsamy;K. Senthilkumar;Kil, Bong-Seop
    • 한국생태학회:학술대회논문집
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    • 한국생태학회 2002년도 VIII 세계생태학대회
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    • pp.93-100
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    • 2002
  • Dynamics of certain $N_2$fixing bacteria such as Rhizobium, Azospirillum and Azotobactor, nodule number in dominant legume, Atylosia trinervia, P-solubilizing bacteria, actinomycetes and fungi were studied in unburned and burned site of natural grassland, southern India. Population of $N_2$- fixing bacteria, P-solubilizing bacteria, fungi and nodule number in legume increased significantly in burned sites. On the other hand, the actinomycetes population remained unchanged. Thirty six species of fungi with tricalcium phosphate solubilizing ability were recorded. The most efficient P-solubilizing fungi recognised in the soils of the study sites are Absidia ramosa, Gongronella butlerii, Mortieralla spinosa, Mucor racemosus, Rhizopus nigricans, R. stolonifer, R. oryzae, Aspergillus fumigatus, A. nidulans, A. niger Theilavia terricola and Cheatomium lunasporium.

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Comparison of Mating Systems in Populations of Gleditsia japonica var. koraiensis

  • Huh, Man-Kyu
    • Journal of Ecology and Environment
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    • 제29권5호
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    • pp.411-414
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    • 2006
  • The mating systems of two groups of natural populations of Gleditsia japonica var. koraiensis in Korea were determined using allozyme analysis. The result suggests that G. japonica var. koraiensis is predominantly outcrossing. The tm values of eight populations in Korea varied from 0.667 (Mdh-1) to 0.938 (ldh-1), giving an average 0.820. Population and individual outcrossing estimates were associated with flowering tree density or degree of spatial isolation. The reason for relatively low outcrossing rates of some populations could be attributed to reduction of effective population sizes of sib for the medicine, small population size, and isolation of flowering mature trees. The heterozygote excesses were observed in some natural populations, whereas other populations exhibited varying degrees of inbreeding and heterozygotes deficit. Thus, selection against homozygotes operated in the progeny populations throughout the life cycle.

Impact of Surface Fire on the Dynamics of N2- Fixing and P - Solubilizing Microbial Population in Natural Grassland Soils, Southern India

  • Manian, S;Paulsamy, S.;Senthilkumar, K.;Kil, Bong-Seop
    • The Korean Journal of Ecology
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    • 제25권4호
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    • pp.227-234
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    • 2002
  • Dynamics of certain $N_2$ fixing bacteria such as Rhizobium, Azospirillum and Azotobactor, nodule number in dominant legume, Atylosia trinervia, P-solubilizing bacteria, actinomycetes and fungi were studied in unburned and burned site of natural grassland, southern India. Population of $N_2$ - fixing bacteria, P-solubilizing bacteria, fungi and nodule number in legume increased significantly in burned sites. On the other hand, the actino-mycetes population remained unchanged. Thirty six species of fungi with tricalcium phosphate solubilizing ability were recorded. The most efficient P-solubilizing fungi recognised in the soils of the study sites are Absidia ramosa, Gongronella butlerii, Mortieralla spinosa, Mucor racemosus, Rhizopus nigricans, R. stolonifer, R. oryzae, Aspergillus fumigatus, A. nidulans, A. niger, Theilavia terricola and Cheatomium lunasporium.

한국과 아시아지역 국가의 도시화 경향 (Korean Urbanization in The Asian Context)

  • Huguet, Jerrold W.
    • 한국인구학
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    • 제10권2호
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    • pp.82-98
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    • 1987
  • The urban population in Asia more than doubled between 1960 and 1985, growing by 3.0 percent per annum on average. Yet during that period, the proportion of the total population living in urban areas increased only from 21 to 27 percent. This seeming paradox is explained by the relatively high rates of rural population growth in Asia, which averaged 1.8 percent over the same period. The Republic of Korea has experienced the most rapid rate of urbanization in Asia during the past century. The proportion urban jumped from 28 percent in 1960 to 65 percent in 1985. There is a clear association between economic growth and the pace of urbanization in Asia. Currently natural increase accounts for about 60 percent of urban growth, but the speed of urbanization is projected to increase after 1990, and migration, reclassification and annexation will comprise about half of urban growth, Seoul is currently the fourth largest urban agglomeration in Asia, and its population is projected to be over 13 million by the end of the century. It is argued that policies to deconcentrate urban population will not be generally successful in Asia and that governments should attempt to manage the growth of large metropolitan areas more efficiently.

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