• Title/Summary/Keyword: Natural Extract

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Phytochemical Studies on Paeoniae Radix (1);Monoterpene Glucosides (작약(芍藥)의 성분연구(成分硏究) (1);Monoterpene glucoside의 분리)

  • Yean, Min-Hye;Lee, Joo-Young;Kim, Ju-Sun;Kang, Sam-Sik
    • Korean Journal of Pharmacognosy
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    • v.39 no.1
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    • pp.19-27
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    • 2008
  • From the polar fractions of 70% EtOH extract of Paeonia lactiflora roots (Paeoniaceae), ten monoterpene glucosides were isolated and identified as lactiflorin (1), benzoylpaeoniflorin (2), mudanpioside C (3), $1-O-{\beta}-D-glucosylpaeonisuffrone$ (4), paeonidanin (5), $1-O-{\beta}-D-glucosyl-8-O-benzoylpaeonisuffrone$ (6), paeoniflorin (7), albiflorin (8), oxypaeoniflorin (9) and mudanpioside E (10) by spectroscopic methods. Among these glucosides, 3-6 and 10 were isolated for the first time from this plant.

Phytochemical Constituents of Sagittaria trifolia (벗풀의 식물화학적 성분)

  • Kim, Ki-Tack;Moon, Hyung-In;Lee, Kang-Ro;Zee, Ok-Pyo
    • YAKHAK HOEJI
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    • v.42 no.2
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    • pp.140-143
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    • 1998
  • From the methanol extract of the whole part of Sagittaria trifolia ergosterol peroxide, icariside D2. Thalictoside and 4-nitrophenyl $\{beta}$-D-glucopyranoside wer e isolated and their structures were identified by the physico-chemical and spectral data. This is the first report of these compounds from S. trifolia.

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A New Megastigmane Glucoside from the Aerial Parts of Erythronium japonicum

  • Lee, Seung-Young;Lee, Il-Kyun;Choi, Sang-Un;Lee, Kang-Ro
    • Natural Product Sciences
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    • v.18 no.3
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    • pp.166-170
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    • 2012
  • The purification of the MeOH extract from the aerial parts of Erythronium japonicum using column chromatography furnished a new megastigmane glucoside, erthrojaponiside (1), together with six known megastigmane derivatives (2 - 7). The structure of the new compound (1) was determined through 1D and 2D NMR spectral data analysis and chemical means. The isolated compounds (1 - 7) were tested for cytotoxicity against four human tumor cells in vitro using a Sulforhodamin B (SRB) bioassay.

Isolation of Hepatoprotective Phenylpropanoid from Lactuca indica

  • Kim, Ki-Hyun;Kim, Young-Ho;Lee, Kang-Ro
    • Natural Product Sciences
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    • v.16 no.1
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    • pp.6-9
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    • 2010
  • In continuing our search for biologically active compounds from Korean Compositae medicinal plants, we investigated the constituents of the aerial parts of Lactuca indica L. and isolated a phenylpropanoid derivative from its MeOH extract. The chemical structure was characterized by spectroscopic methods, including 1D and 2D NMR to be di-E-caffeoyl-meso-tartaric acid (1). Compound 1 was isolated for the first time from this plant. In this paper, we suggest that the NMR assignment at C-2 of (+)-taraxafolin-B should be corrected. In the human HBV-transfected liver cell line HepG2.2.15, the compound 1 effectively reduced HBV DNA level in the release of mature HBV particles from HepG2.2.15 cultivation.

Anti-platelet Effect of the Phenolic Constituents Isolated from the Leaves of Magnolia obovata

  • Pyo, Mi-Kyung;Koo, Yean-Kyoung;YunChoi, Hye-Sook
    • Natural Product Sciences
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    • v.8 no.4
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    • pp.147-151
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    • 2002
  • In the course of our work on anti-platelet constituents from plants, eight phenolic compounds, $({\pm})-syringaresinol$ (1), 4-hydroxybenzaldehyde (2), 4-hydroxybenzoic acid (3), vanillic acid (4), 4-hydroxy cinnamic acid (5), quercetin 3-O-rhamnoside (6), rutin (7), and quercetin $3-(2^G-rhamnosylrutinoside)$ (8) were isolated from the methanol extract of the leaves of Magnolia obovata. The compounds were identified based on the spectroscopic data. Compound 2, 3, 5, 6, 7 and 8 were isolated for the first time from genus Magnolia. 1 and 6 showed same order of inhibitory potencies as acetylsalicylic acid (ASA) to rat platelet aggregation induced by all the stimulators tested. The remaining six compounds showed only mild effects.

Platelet Anti-Aggregatory Effects of Coumarins from the Roots of Angelica genuflexa and A. gigas

  • Lee, Yong-Yook;Lee, Sang-Hyun;Jin, Jing-Ling;Yunchoi, Hye-Sook
    • Archives of Pharmacal Research
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    • v.26 no.9
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    • pp.723-726
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    • 2003
  • Five coumarins, isoimperatorin (1), pabulenol (2), isooxypeucedanin (3), oxypeucedanin hydrate (4) and osthol (5) were isolated from the MeOH extract of Angelica genuflexa in the course of searching for anti-platelet and anti-coagulant components from plants. Pabulenol (2) was isolated from A. genuflexa for the first time. The five compounds isolated from A. genuflexa, together with decursinol angelate (6), decursin (7) and nodakenin (8) from A. gigas were evaluated for their effects on platelet aggregation and blood coagulation. Compounds 2, 5, 6 and 7 were observed to be either equally effective or 2∼4 times more inhibitory than ASA in both arachidonic acid and U46619 ($TXA_2$ mimetic) induced platelet aggregations.

Platelet Anti-aggregating and Anti-oxidative Activities of 12-O-(4'-O-methyl-galloyl)-bergenin, a Novel Compound Isolated from Crassula cv. "Himaturi"

  • Lee, Yong-Yook;Jang, Dae-Song;Jin, Jing-Ling;YunChoi, Hye-Sook
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.193.3-194
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    • 2003
  • Platelets play critical roles in both hemostasis and thrombosis. It was reported that platelet aggregation is associated with an increase in superoxide production and can be inhibited by hydroxyl radical scavengers. In the course of our search for the anti-platelet, anti-coagulant and/or anti-oxidative components from plants, the MeOH extract of Crassula cv. "Himaturi" (Crassulaceae) was observed to have both anti-aggregatory and anti-coagulant effects. A novel compound, 12-O-(4'-O-methyl-galloyl)-bergenin (1), was isolated as an active component from the EtOAC soluble fraction. (omitted)

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Preparation of Alginate-Chitosan Microcapsules and Enteric Coated Granules of Mistletoe Lectin for Oral Administration

  • Lyu, Su-Yun;Moon, You-Sun;Kwon, Young-Ju;Park, Won-Bong
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.204.2-204.2
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    • 2003
  • The aqueous extract of European mistletoe (Viscum album, L.) has been used in cancer therapy. The purified mistletoe lectins, main components of mistletoe, have demonstrated cytotoxic and immune-system-stimulating activities. Korean mistletoe (Viscum album L. coloratum), a subspecies of European mistletoe, has also been reported to possess anticancer and immunological activities. A galactose- and N-acetyl-D-galactosamine- specific lectin (Viscum album L. coloratum agglutinin, VCA) with Mr 60 kDa was isolated from Korean mistletoe. (omitted)

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Natural Dye Extraction from Merbau (Intsia bijuga) Sawdust: Optimization of Solid-Solvent Ratio and Temperature

  • Aswati MINDARYANI;Ali SULTON;Felix Arie SETIAWAN;Edia RAHAYUNINGSIH
    • Journal of the Korean Wood Science and Technology
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    • v.51 no.6
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    • pp.481-492
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    • 2023
  • The ecofriendly lifestyle has attracted considerable support for sustainable development. Natural dyes, as sustainable products, have become a research focus and development area for many scientists. Ecofriendly processing also supports circular sustainable development. This study effectively obtained tannins as a natural dye from merbau (Intsia bijuga) sawdust using water as an ecofriendly solvent. Merbau sawdust is an underutilized industrial waste. Temperature and solid-solvent ratio variations were performed to extract tannins from merbau sawdust. Temperature and solid-solvent ratio positively affected solution yield and tannin concentration. The optimal condition was identified using response surface methodology and experimental observations. A yield of 0.2217 g tannins/g merbau was obtained under the conditions of 333.15 K and 0.125 solid-solvent ratio. Extraction was controlled by convective mass transfer at the interface of solid particles.

Functional Cosmetic Characteristics of Grape Skin Extract (포도껍질 추출물의 기능성 화장품 소재 특성)

  • Shin, Eun Min;Kim, Ju Yeon;Park, Si Eun;Kim, Chang-Joon
    • Clean Technology
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    • v.27 no.4
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    • pp.306-314
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    • 2021
  • Grape skins are a natural resource rich in antioxidants, but people only eat grape flesh and have discarded the skins. This study investigated the possibility of using grape skin extract as a raw material for functional cosmetics. The dried grape skin powder was put in distilled water and stirred for 1 h, and then the supernatant separated from the solid was used as an extract. The extract yield was 17.8 ~ 31.4%, and the total flavonoid and polyphenol contents in the extract were 1.8 ~ 2.5 mg-QE g-extract-1 and 16.9 ~ 20.3 mg-GAE g-extract-1, respectively. The extract effectively removed radicals of DPPH and ABTS, and the degree of scavenging increased with the concentration of the extract. The extract inhibited the collagen hydrolysis activity of collagenase, and the activity inhibition rate increased to 84.2% as the extract concentration increased. However, notable inhibition of tyrosinase by the extract was not found. As the extract of Chamaecyparis obtusa was added to the grape-skin extract, the tyrosinase inhibition rate increased, but the DPPH radical scavenging activity decreased. This study found that grape skin extract has a high antioxidant capacity and anti-wrinkle effect but a low whitening effect. However, by mixing the grape skin extract with the extract of C. obtusa in an optimal ratio, the whitening effect was improved with excellent antioxidant and anti-wrinkle effects.