• Particle and aerosol research
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• v.18 no.2
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• pp.37-50
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• 2022

Due to the syndrome coronavirus 2 (SARS-CoV-2) pandemic, the subway passenger cabin should be continuously sterilized. However, a disinfectant such as chlorine is toxic and can lead to different issues to human health. In this paper, we introduced a novel disinfectant based on natural product (Dendropanax morbifera extract). Via ultra-high performance liquid chromatography - mass spectrometer (UHPLC-MS), different compounds from Dendropanax morbifera extract showed antivirus potentials. Antimicrobial experiments confirmed that the air-disinfectant containing Dendropanax morbifera can eliminate harmful microorganisms including Gram (-), Gram (+), and yeast within 5 mins. The as-prepared air-disinfectant also showed high antivirus activity against H1N1, HRV, and EV71. Deodorization test also indicates that the as-prepared air-disinfectant can lower the harmful gas such as ammonia and trimethylamine in the atmosphere. To evaluate the potential of air-disinfectant containing Dendropanax morbifera in practical applications, different safety tests including acute oral toxicity, acute skin irritation, and eye irritation were conducted. Results showed that the as-prepared disinfectant did not negatively affect tested animals during these safety investigations.

• Journal of Environmental Health Sciences
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• v.49 no.2
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• pp.99-107
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• 2023

Background: Excessive alcohol consumption is at the root of serious social problems such as hangovers, liver dysfunction, and alcoholism. Objectives: This study was carried out to determine the hangover ameliorating effect of fermented rice extract and a combination of yeast-fermented powder and lysate containing aldehyde dehydrogenase (ALDH) (improved new ingredients) in an ethanol-induced rat study. Methods: The concentrations of alcohol, acetaldehyde, and malondialdehye in serum were evaluated to assess the anti-alcohol and anti-aldehyde hangover effect in two experiments, one with fermented rice extract) and a second with yeast-fermented powder and lysate, using animal studies. Results: Experiment 2 with yeast-fermented powder and lysate containing ALDH showed similar and higher activity, respectively, in reducing ethanol and acetaldehyde concentration compared with Experiment 1 with fermented rice extract. Experiment 2 also significantly reduced malondialdehyde, a type of lipid peroxide. The ALDH-related compound (ARC) lysate showed better hangover relief effect than ARC powder. Conclusions: These results indicate that ALDH-related compounds exhibit a hangover relief effect, and fermented lysate is considered to be a better candidate for hangover relief.

• Fashion & Textile Research Journal
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• v.26 no.2
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• pp.190-197
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• 2024

With increasing global interest in environmentally friendly materials and the consequent rise in demand, there is a growing need for alternatives to synthetic fibers, which can cause skin diseases and other side effects. The fashion industry is emphasizing material sustainability owing to concerns about increasing carbon emissions. Moreover, consumers express a strong desire for ecofriendly and sustainable materials. Therefore, clothing brand companies are developing eco-friendly products to enhance their corporate image. Hemp fibers are recognized for their functionality and are utilized as crucial materials in the development of eco-friendly products by global fashion companies. In this study, we produced socks that effectively improve foot health using hemp stem bark extract fibers and demonstrated the positive efficacy of natural fibers through functional and wearability evaluations. Hemp stem bark extract fibers showed 99.9% antimicrobial effectiveness against bacteria responsible for sweat-induced bacterial proliferation and odor, when blended with lyocell fibers and woven into fabric to manufacture socks. Wearability evaluations of these terry cloth socks confirmed a reduction in foot odor and fatigue among the participants with a consumer satisfaction of 4.63/5. These findings confirm the effectiveness and positive impact of the natural antimicrobial properties of hemp fibers and terry cloth structure in improving foot health.

• Journal of Microbiology and Biotechnology
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• v.10 no.1
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• pp.16-20
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• 2000

The aqueous extract from the cultural mycelium of Paecilomyces japonica showed cytotoxicity against several tumor cells including Jurkat, U937, HL-60, HepG2, BW5147.G.1.4, and NIH3T3. When the aqueous extract was fractionated by sequential organic solvent extractions using n-hexane and ethyl acetate, the ethyl acetate fraction appeared to contain the most cytotoxic activity, and the $IC_{50}$ values for various tumor cells were in the range from 1.5 to $10.0{\;}\mu\textrm{g}/ml$. To elucidate the cellular mechanism underlying the induced cytotoxicity, the apoptotic DNA fragmentation along with the cell cycle proression was examined in Jurkat T cells following the ethyl acetate fraction treatment. In the presence of $2.5{\;}\mu\textrm{g}/ml$ of the ethyl acetate fraction, apoptotic DNA fragmentation of the cells was detected within 1 h and increased upto 24 h in a time-dependent manner. Under the same conditions, a sub-G1 peak was detectable by flow cytometry. These results indicate that the cytotoxic effect of P. japonica on tumor cells is attributable to the induced apoptosis.

• Proceedings of the SCSK Conference
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• 2003.09a
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• pp.820-829
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• 2003

One of the important function of skin is the protection from harmful environments. Many studies were carried out to keep the skin from wrinkling and pigmenting. Skin wrinkle and pigmentation could be caused' by the unusual disruption of connective tissue, the formation of free radicals and the radiation of ultraviolet. In this study, the extracts obtained from 23 different kinds of medicinal plants were examined whether they have inhibitory effect on tyrosinase and elastase as well as free radical scavenging effect. All the extracts examined were obtained by using 70% (v/v) ethanol at $60^{\circ}C$. It has been found that there were two medicinal plants which have positive effects matching with the purpose of this study. The extract of Ephedra sinica stapf shows an inhibitory effect on tyrosinase ($IC_{50}$ = 83.7~$\mu\textrm{g}$/ml), on elastase ($IC_{50}$ = $690{\mu}\textrm{g}$/ml), and also shows free radical scavenging effect ($IC_{50}$ = 29.6$\mu\textrm{g}$/ml). The extract of Betula platyphylla Var. shows an inhibitory effect on elastase ($IC_{50}$ = 498.1$\mu\textrm{g}$/ml), and free radical scavenging effect ($IC_{50}$ = 9$\mu\textrm{g}$/ ml). The aim of the study is to find the natural compounds which have function in skin-lightening, anti-wrinkling and anti-oxidation, with safe and active ingredients in cosmetic.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.30 no.1
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• pp.117-122
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• 2004

Exessive UV radiation causes a lot of problems in our skin. In order to find out the alternative UV absorber that can safely be used in cosmetics, we have screened various natural extracts in terms of their UV absorbing effect. Some natural extracts, which possess antioxidative activities, have also been found to retard the oxidation process in our experiment. Natural compound such as 7-hydroxycymopol, baicalein, etc. could be transformed into adjuvant UV absorber by chemical modification. In cosmetics, its chemical stability against UV radiation, exposure to oxygen and other factors could be improved by using the silicone or W/S type emulsion. The values of MED (minimal erythema dose) were improved to 0.10 ${\pm}$ 0.02∼0.11 ${\pm}$ 0.02 by adding this natural extract into the cosmetic formulations. In conclusion, the results of the present study show that natural extracts could be used as an adjuvant UV absorber, if they are stabilized.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.7
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• pp.971-975
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• 2003

This study was performed to find natural foods with high anti-dementia effects from natural plant resources which have been used for mental health. We screened inhibitors of prolyl endopeptidase which could be implicated in the processing of Alzheimer's disease, the principal part of dementia. One hundred natural foods were examined for prolyl endopeptidase inhibitors. Out of them, methanol extract of Acorns and Raspberry inhibited more than 90% of prolyl endopeptidase activity at 40 ppm. Also, methanol extract of Walnut inhibited 73% of prolyl endopeptidase activity at the same concentration. Therefore, the result suggests that these natural foods may have the potential to be used for preventing and treating dementia like Alzheimer disease.

• Journal of the Korean Applied Science and Technology
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• v.29 no.3
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• pp.402-411
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• 2012

Natural Bokbunja is used as a material of oriental medicine which it obtains from Rubus or Raspberry. Natural Bokbunja Rubus has natural odor and taste, natural color, and pharmaceutical & chemical characteristics. This experiment tested antimicrobial experiment against microbe and dye experiment against fiber using natural Bokbunja extract. Some conclusions from this characteristics experiment were obtained as follow. The result of antimicrobial experiment could know that ATCC-001(staphylococcus aureus) does not show nearly from 72hrs after cultivation test and ATCC-002(aspergillus niger) shows to propagate continuously according to passage of time. Also, the result of dye experiment could know that cotton and silk using alum mordant($Al_2(SO_4)_3{\cdot}13-14H_2O$) against fiber shows in direction of light beige color. The result of instrument analysis ascertained inorganic components of K(221.100ppm), Mg(17.920ppm), Ca(5.129ppm), Na(2.940ppm), Si(0.638ppm) etc from Bokbunja with ICP/OES, and ascertained organic components of boric acic(1.711), silane(2.142), pyrazole(3.481), propyl isothiocyanate(2.565), furfurole(11.521) etc from Bokbunja with GC/MSD.

• Journal of Life Science
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• v.17 no.1 s.81
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• pp.137-142
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• 2007

For the production of natural pigments with microbe, the strains which produced monascus pigment were isolated, and then culture condition and extraction condition were investigated. These results are summarized as follows; The strain which ran produce monascus natural pigment was isolated from natural microbial sources and we made mutant of this strain with UV($235_{nm}$, 30 second) irradiation. The mutant was identified as Monascus sp. MK2-2. The optimal culture conditions were investigated optimal medium containing 0.3% rice powder, 0.2% yeast extract, 0.3% $NH_4H_2PO_4$ and $30^{\circ}C$ in a rotary shaker (120 rpm) for 5 days (initial pH 5.0), while the pigment production was determined at 24 hr intervals. The effective carbon sources were wheat flour > rice powder > fructose, and effective nitrogen sources were sodium nitrate > $KNO_3$ for production of the monascus natural pigment. The pigment capacity is good from 17 to 22 in C/N ratio. The production amount of monascus natural pigment was 0.38 g per 1 kg of rice. Also, extract of red yeast rice had anti-thrombosis activity like a degree of aspirin.

• Journal of Life Science
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• v.26 no.8
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• pp.936-942
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• 2016

As the incidence of environmental diseases is increasing due to harmful environmental factors, there is a rising interest in developing eco-friendly materials for housing. In this study, we sought to develop antimicrobial interior fabric blind materials by employing ethanol extract of a medicinal plant Zanthoxylum piperitum DC. As determined by the disc diffusion method, the zones of inhibition of the pericarp ethanol extract at a concentration of 5 mg/disc against Klebsiella pneumoniae, Staphylococcus aureus, and Streptococcus mutans were 13.5±1.5 mm, 14.0±0.5 mm and 15.0±0.1 mm, respectively, whereas the leaf ethanol extract (5 mg/disc) against K. pneumoniae, S. aureus, and S. mutans were 12.8± 0.3 mm, 13.5±1.0 mm, and 12.0±0.1 mm, respectively. The IC₅₀ of the leaf ethanol extract against K. pneumoniae, S. aureus and S. mutans were about 0.5 mg/ml, 0.1 mg/ml and 1.0 mg/ml respectively. To examine whether the leaf ethanol extract possessing antibacterial activity of Z. piperitum DC can be applicable to production of antimicrobial fabric blind materials, the fabrics treated with either 1.0% or 2.0% of the leaf ethanol extract were tested for antibacterial activity against K. pneumoniae and S. aureus using International Standard Fabrics Test Method. The results indicate that the fabric treated with the ethanol extract of Z. piperitum DC possesses an excellent antimicrobial activity against both pathogenic bacteria. These results suggest that Z. piperitum DC may be applicable to producing functional fabrics which are effective in reducing the harmful bacterial factors in indoor environments.