• BMB Reports
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• 제55권10호
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• pp.512-517
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• 2022

Traumatic brain injury (TBI) is brain damage which is caused by the impact of external mechanical forces. TBI can lead to the temporary or permanent impairment of physical and cognitive abilities, resulting in abnormal behavior. We recently observed that a single session of early exercise in animals with TBI improved their behavioral performance in the absence of other cognitive abnormalities. In the present study, we investigated the therapeutic effects of continuous exercise during the early stages of TBI in rats. We found that continuous low-intensity exercise in early-stage improves the locomotion recovery in the TBI of animal models; however, it does not significantly enhance short-term memory capabilities. Moreover, continuous early exercise not only reduces the protein expression of cerebral damage-related markers, such as Glial Fibrillary Acid Protein (GFAP), Neuron-Specific Enolase (NSE), S100β, Protein Gene Products 9.5 (PGP9.5), and Heat Shock Protein 70 (HSP70), but it also decreases the expression of apoptosis-related protein BAX and cleaved caspase 3. Furthermore, exercise training in animals with TBI decreases the microglia activation and the expression of inflammatory cytokines in the serum, such as CCL20, IL-13, IL-1α, and IL-1β. These findings thus demonstrate that early exercise therapy for TBI may be an effective strategy in improving physiological function, and that serum protein levels are useful biomarkers for the predicition of the effectiveness of early exercise therapy.

• 문화기술의 융합
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• 제9권5호
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• pp.729-736
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• 2023

4차 산업혁명의 본격화로 지능정보기술의 혁신적 발전·활용 확대와 함께 행정서비스에 대한 질적 개선과 수요가 급증하면서 정부는 조직의 운영, 업무처리, 의사결정, 행정서비스 등 기존 전자정부 운영의 디지털 혁신을 통한 '디지털플랫폼 정부 구축'을 본격화하고 있다. 지방자치단체 역시 디지털 기반의 애자일(Agile) 정부 구축을 핵심 전략으로 추진함에 따라 본연구에서는 지능정보화를 통한 디지털 전환 정책 및 사업을 뒷받침할 광역·기초자치단체의 정보화 전문인력 운영 실태를 조사·분석함으로써 성공적인 디지털 전환을 위한 인적자원 규모 확대의 필요성과 시사점을 도출하였으며 신규 인력을 확보하는 과정에서 역량과 전문성을 제고하기 위한 두 가지 방안을 제시하였다.

• Journal of Information Processing Systems
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• 제20권3호
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• pp.391-398
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• 2024

Given the further promotion of economic globalization, China's financial market has also expanded. However, at present, this market faces substantial risks. The main financial and economic risks in China are in the areas of policy, credit, exchange rates, accounting, and interest rates. The current status of China's financial market is as follows: insufficient attention from upper management; insufficient innovation in the development of the financial economy; and lack of a sound financial and economic risk protection system. To further understand the current situation of China's financial market, we conducted a questionnaire survey on the financial market and reached the following conclusions. A comprehensive enterprise questionnaire from the government's perspective, the enterprise's perspective and the individual's perspective showed that the following problems exist in the financial and economic risk prevention aspects of big data and Internet of Things in China. The political system at the country's grassroots level is not comprehensive enough. The legal regulatory system is not comprehensive enough, leading to serious incidents of loan fraud. The top management of enterprises does not pay enough attention to financial risk prevention. Therefore, we constructed a financial and economic risk prevention model based on big data and Internet of Things that has effective preventive capabilities for both enterprises and individuals. The concept reflected in the model is to obtain data through Internet of Things, use big data for screening, and then pass these data to the big data analysis system at the grassroots level for analysis. The data initially screened as big data are analyzed in depth, and we obtain the original data that can be used to make decisions. Finally, we put forward the corresponding opinions, and their main contents represent the following points: the key is to build a sound national financial and economic risk prevention and assessment system, the guarantee is to strengthen the supervision of national financial risks, and the purpose is to promote the marketization of financial interest rates.

• 벤처창업연구
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• 제12권1호
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• pp.33-46
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• 2017

우리나라의 중소기업은 전체 사업체 수의 99.8%, 종사자 비중의 87.9%, 전체 생산액의 48.3%를 차지하는 등 국가경제의 근간을 형성하고 있으며, 기술혁신, 고용창출, 산업의 다양성, 지역균형개발 등 여러 측면에서 국민경제 발전에 있어서 실질적인 원동력이 되고 있다. 이로 인해 중소기업은 기술혁신을 통해서 기술역량을 확보하는 것이 더욱더 필요해졌다. 하지만 대부분의 중소기업은 자금부담 능력, 연구인력, 연구장비 등 R&D 역량이 대체적으로 부족한 실정이다. 이에 정부에서는 중소 중견기업 지원을 위해서 정부 출연(연)을 통해 다양한 지원을 강화하고 있다. 즉, 출연(연)은 산업 전반의 혁신활동을 증진시키고, 기업의 기술역량을 강화하기 위해 연구개발 (R&D)을 통해 창출된 지식과 기술을 꾸준히 시장에 제공하고 있으며, 중소 벤처기업이 견실한 기업으로 도약할 수 있도록 인력지원, 연구시설/장비지원 등을 통해 기업들을 지원하는 역할을 수행하고 있다. 이 시점에서 정부와 정부 출연(연)이 우리 경제에서 중요한 역할을 하고 있는 중소 벤처기업들을 효과적으로 지원하기 위해서는 기술이전 및 전략적 제휴(기술협력)와 관련해서 기업성과에 미치는 영향요인에 대해 정확히 알아야 된다. 본 연구는 중소 벤처기업의 기업성과에 영향을 미치는 요인에 있어 기술이전경험 및 기술협력유형의 내용별로 어떠한 영향을 미치는지 알아보고자 1,104개 기업을 대상으로 실증적으로 분석하였다. 감마회귀분석을 실시한 결과, 기술이전경험과 기술협력유형이 중소 벤처기업의 매출액에 유의미한 영향을 미치는 것으로 나타났다. 본 연구의 결과는 기술이전경험의 경우, 기술이전경험'3~5회'와 '기술이전경험 무' 간에 유의미한 차이가 있었고, 기술협력유형의 경우, '핵심기술 확보 등 기술역량 제고'와 '개발인력확보'간에 유의미한 차이가 있었다. 이는 기술이전경험의 유무와 기술협력활동의 유형에 따라 달라진다는 것을 보여주고 있어, 향후 정부출연(연)과 중소 벤처기업 간 협력 정책 등 중소 벤처기업의 상호협력 촉진정책을 수립할 때 기초자료로 활용될 것으로 기대된다.

• 실천공학교육논문지
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• 제12권1호
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• pp.61-72
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• 2020

기업가정신은 사회경제적 혁신의 원동력이며, 경제발전과 고용 창출을 선도하는 역할을 한다. 기업가정신의 중요성이 증대됨에 따라 기업가정신교육 방안에 대한 연구가 활성화되고 있으며, 유럽위원회와 OECD를 중심으로 역량모델을 기반으로 기업가정신교육체계를 구축하고 있다. 그러나 국내에서는 아직 역량을 기반으로 한 기업가정신교육에 대한 연구가 거의 이루어지지 않고 있으며, 기업가정신교육의 효과도 낮은 것으로 평가되고 있다. 본 연구는 국내외의 기업가정신교육에 대한 사례분석과 기업가정신역량 및 교육모델에 대한 이론 고찰 및 전문가 의견 수렴을 거쳐서 국내 K 대학에 역량기반의 기업가정신교육모델을 개발하였다. 교육모델은 경영학 중심의 이론 교육을 지양하고, 기업가정신 역량개발에 초점을 맞추었으며, 학생들의 기업가정신역량의 발전단계를 고려한 교육과정을 제시했다.

• Asia Pacific Journal of Business Review
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• 제3권1호
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• pp.57-76
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• 2018

The "Internet of things" (IoT) is becoming an increasingly growing topic of conversation, it is a new emergent technology that can be present in almost every field and application. It's a concept that not only has the potential to impact how people live but also how people work. Broadband Internet and Mobile Internet are becoming more widely available, the cost of the service is decreasing, more devices are being created with Wi-Fi capabilities and sensors built into them, technology costs are going down, and smartphone penetration is growing so fast. All of these facts are creating the best environment for the IoT applications. In a country like Ecuador, is important to have a previous analysis about the feasibility of the implementation of this new technology in order to know what are the challenges the country has to face, and also to not stay behind as the other countries in the region are advancing. Currently, this kind of analysis does not exist. The Internet of Things is an innovation where business and technology models in Ecuador are relatively unexplored. The current infrastructure deployed in Ecuador and the available devices in the market are the central facts to initiate with the research, which is a starting point to show if Ecuador is ready to this technology, and if is not ready what is missing. This study shows the current telecommunications status in Ecuador, and its strengths and weaknesses to start the deployment of Internet of Things. Besides, it also will show the most likely applications that can be easily adopted for the Ecuadorian market with its respective availability, affordability, and adaptability.

• Journal of Korea Trade
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• 제25권3호
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• pp.153-168
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• 2021

Purpose - In this study, we aim to explore new distribution strategies for sustainable growth in the era of the 4th industrial revolution, focusing on SMEs (small and medium-sized enterprises) in Korea, and suggest ways to upgrade the government's official distribution channel to the next level. Design/methodology - First of all, this paper explored the prior research, the current status of sales support for SMEs, and the changes in the distribution industry due to COVID-19 pandemic. Based on Moon (2016)'s ABCD strategic model - Agility, Benchmarking, Convergence, and Dedication, the study then derived directions in which official distribution channels should move and the new distribution strategy for Korean SMEs to secure competitive advantage. Findings - First, in terms of 'Agility', in order to upgrade official distribution channels, which are currently at some competitive disadvantages compared to private distribution companies, we must quickly introduce technologies for the 4th industrial revolution, such as AI, Big Data, etc., and establish precise strategies to strengthen the capabilities of SMEs. Second, in terms of 'Benchmarking', the use of "Chamelezones" has been increasing to enhance the competitiveness of offline stores in line with recent ontact trends. Therefore, official distribution channels should also benchmark such cases, strengthening their competitiveness by utilizing offline spaces more efficiently and effectively. Third, in terms of 'Convergence', in line with the rapidly changing trend of the times, official distribution channels should also promote active partnerships with media commerce, e-commerce and ICT platforms, as well as cooperation with private retailers, and focus on creating synergy effects through them. Finally, from the perspective of 'Dedication', digitalization should be promoted step by step, finding the sector that can accelerate digital among the value chains of official distribution channels, and continuing to discuss how to digitize it realistically. Originality/value - Based on this analysis, we have presented strategies and implications for innovating official distribution channels for SMEs, which will contribute to enhancing the competitive advantage of official distribution channels in the post COVID-19 pandemic era.

• 한국경제지리학회지
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• 제25권4호
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• pp.547-567
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• 2022

최근 산업공간의 새로운 변화와 관련된 논의들이 활발하게 이루어지고 있다. 본 연구는 2000년대 이후 전 세계적으로 도시를 중심으로 급격하게 확산되고 있는 메이커스페이스에 주목하였다. 메이커스페이스는 새로운 산업공간의 핵심적 특징을 잘 보여주면서도 사회운동의 과정을 통해 탄생하는 등 관련 분야의 심도 있는 연구의 필요성이 높다. 이에 본 연구는 산업공간의 도심화에 대한 이론과 그 내부의 장소화에 대한 논의를 토대로 메이커스페이스의 도시성과 장소성을 분석하고 그 함의를 도출하고자 하였다. 먼저, 메이커스페이스의 도시성은 도시 내부의 상업 및 주거지역, 산업시설로 진입하는 현상과 도시의 교육·연구, 산업육성, 문화·여가 등 도시 역량과 연계하는 모습을 통해 나타난다. 또한, 내부에서는 취향의 중시, 자율의 확산, 연결의 강화를 통해 장소성이 형성된다. 본 연구는 미래의 산업공간에 있어 도시 혁신역량과의 결합이 보다 중요해지고 있으며, 그 내부의 가치 창출 매커니즘이 근본적으로 변화하고 있음을 시사한다.

• 대한한의학회지
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• 제44권3호
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• pp.59-73
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• 2023

Objectives: The role of physician-scientists who bridge the gap between basic science and clinical medicine is crucial in advancing medical innovation. This study aims to examine the educational and research environment and career satisfaction of graduate students in Korean Medicine among those who are Korean medicine doctor (KMD). Methods: This study analyzed the results of a survey consisting of respondents' composition, job status, graduate education and job satisfaction, economic conditions, career determinants, and obstacles to the career path of KMD-scientists from 65 participants including both full-time and part-time graduate students. Results: The results revealed significant differences between full-time and part-time graduate students in terms of weekly hours spent and job priorities, motivation for entering graduate school, career preferences, and desired career paths. The study highlights the need for tailored support for full-time and part-time graduate students and the importance of economic assistance in fostering KM scientists. Economic difficulties were identified as a major obstacle for full-time graduate students pursuing research careers. Tuition fees were found to be a significant burden for all graduate students. Furthermore, it emphasizes the importance of enhancing the research capabilities of part-time graduate students and improving the quality of education to foster KMD-scientists. Conclusion: This research provides essential insights for Korean Medicine colleges and graduate schools to develop targeted improvement plans and effectively train KMD-scientist.

• 동의생리병리학회지
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• 제38권2호
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• pp.49-58
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• 2024

The rapid advancement of generative large language models has revolutionized various real-life domains, emphasizing the importance of exploring their applications in healthcare. This study aims to examine how generative large language models are implemented in the medical domain, with the specific objective of searching for the possibility and potential of integration between generative large language models and East Asian medicine. Through a comprehensive current state analysis, we identified limitations in the deployment of generative large language models within East Asian medicine and proposed directions for future research. Our findings highlight the essential need for accumulating and generating structured data to improve the capabilities of generative large language models in East Asian medicine. Additionally, we tackle the issue of hallucination and the necessity for a robust model evaluation framework. Despite these challenges, the application of generative large language models in East Asian medicine has demonstrated promising results. Techniques such as model augmentation, multimodal structures, and knowledge distillation have the potential to significantly enhance accuracy, efficiency, and accessibility. In conclusion, we expect generative large language models to play a pivotal role in facilitating precise diagnostics, personalized treatment in clinical fields, and fostering innovation in education and research within East Asian medicine.