• 제목/요약/키워드: National University

검색결과 285,419건 처리시간 0.153초

Effective conformation of HIV NNRTI Trovirdine analogs

  • Jung, Sang-Hun;Kim, Il-Whan;Kim, Jin-Myoung;Han, Sang-Sub;Joe, Soo-Hyun;Lee, Jee-Hyun;Lee, Chong-Kyo;Park, Kyung-Lae
    • 대한약학회:학술대회논문집
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    • 대한약학회 2001년도 Proceedings of International Convention of the Pharmaceutical Society of Korea
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    • pp.240.2-240.2
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    • 2001
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New polyacetylenes from Gymnaster Koraiensis

  • Park, J.Y.;Jung, H.J.;Ren-Bo An;;Kim, Y.K.;Na, M.K.;Chu, B.Y.;Kim, Y.H;Bae, K.H.
    • 대한약학회:학술대회논문집
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    • 대한약학회 2000년도 NEW STRATEGY FOR DRUG DEVELOPMENT IN POST-GENOMIC ERA(대한약학회)
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    • pp.229.1-229.1
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    • 2000
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전단교통사고에 의한 광범위 간장손상 - 보존치료 1례 (Extensive Blunt Hepatic Injury due to Cross-over Traffic Accident - A Case Report of Conservative Management)

  • 장인석;김성환;이정은;김종우;최준영;신일우;김현옥
    • Journal of Trauma and Injury
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    • 제27권3호
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    • pp.84-88
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    • 2014
  • The severity of blunt hepatic injury correlates with internal organ damage. We experienced a patient, who had an extensive crushed liver injury. The patient was a 28-year-old man, who was involved in a traffic accident in which a wheel ran over his right upper abdomen. A grade V severe hepatic laceration was diagnosed with computed tomography. His vital signs were stable, so we could wait for times with conservative management. Bile leakage led to biloma and bile spillage into the peritoneal space. Selective percutaneous drainage was needed to control the several biloma. After four months of conservative management, could the patient was discharged in good condition.

Prognostic significance of sequential 18F-FDG PET/CT during frontline treatment of peripheral T cell lymphomas

  • Ga-Young Song;Sung-Hoon Jung;Seo-Yeon Ahn;Mihee Kim;Jae-Sook Ahn;Je-Jung Lee;Hyeoung-Joon Kim;Jang Bae Moon;Su Woong Yoo;Seong Young Kwon;Jung-Joon Min;Hee-Seung Bom;Sae-Ryung Kang;Deok-Hwan Yang
    • The Korean journal of internal medicine
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    • 제39권2호
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    • pp.327-337
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    • 2024
  • Background/Aims: The prognostic significance of 18F-fluorodeoxyglucose (FDG)-positron emission tomography-computed tomography (PET/CT) in peripheral T-cell lymphomas (PTCLs) are controversial. We explored the prognostic impact of sequential 18F-FDG PET/CT during frontline chemotherapy of patients with PTCLs. Methods: In total, 143 patients with newly diagnosed PTCLs were included. Sequential 18F-FDG PET/CTs were performed at the time of diagnosis, during chemotherapy, and at the end of chemotherapy. The baseline total metabolic tumor volume (TMTV) was calculated using the the standard uptake value with a threshold method of 2.5. Results: A baseline TMTV of 457.0 cm3 was used to categorize patients into high and low TMTV groups. Patients with a high TMTV had shorter progression-free survival (PFS) and overall survival (OS) than those with a low TMTV (PFS, 9.8 vs. 26.5 mo, p = 0.043; OS, 18.9 vs. 71.2 mo, p = 0.004). The interim 18F-FDG PET/CT response score was recorded as 1, 2-3, and 4-5 according to the Deauville criteria. The PFS and OS showed significant differences according to the interim 18F-FDG PET/CT response score (PFS, 120.7 vs. 34.1 vs. 5.1 mo, p < 0.001; OS, not reached vs. 61.1 mo vs. 12.1 mo, p < 0.001). Conclusions: The interim PET/CT response based on visual assessment predicts disease progression and survival outcome in PTCLs. A high baseline TMTV is associated with a poor response to anthracycline-based chemotherapy in PTCLs. However, TMTV was not an independent predictor for PFS in the multivariate analysis.