• Journal of Multimedia Information System
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• v.3 no.3
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• pp.97-102
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• 2016

Deep learning enables machines to have perception and can potentially outperform humans in the medical field. It can save a lot of time and reduce human error by detecting certain patterns from medical images without being trained. The main goal of this paper is to build the optimal model for breast mass classification by applying various methods that influence the performance of Convolutional Neural Network (CNN). Google's newly developed software library Tensorflow was used to build CNN and the mammogram dataset used in this study was obtained from 340 breast cancer cases. The best classification performance we achieved was an accuracy of 0.887, sensitivity of 0.903, and specificity of 0.869 for normal tissue versus malignant mass classification with augmented data, more convolutional filters, and ADAM optimizer. A limitation of this method, however, was that it only considered malignant masses which are relatively easier to classify than benign masses. Therefore, further studies are required in order to properly classify any given data for medical uses.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.24 no.4
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• pp.281-299
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• 2013

The purpose of this study is to suggest improvements of pharmacy field in the KDC 6th edition. To achieve this purpose, first, this study reviewed academic area and system of pharmacy. Second, we analyzed headings of pharmacy field from first edition to 6th edition. Third, we analyzed change process of classification items in pharmacy field. Forth, we investigated general problems concerning pharmacy field in the KDC 6th edition based on the comparative analysis with DDC, NLMC, and Research Field Code by Korean Research Foundation. As a result, pharmacy field of KDC has never changed since its 4th edition. And then, this study was added new subjects related to sections and subsections of pharmacy and suggested modern terminology. Also newly assigned pharmaceutics industry, cancer treatment and biological pharmaceutics fields under 518.7-.8 which do not use in pharmacy field for efficient classification.

• 한국약용작물학회:학술대회논문집
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• 2010.10a
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• pp.236-237
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• 2010

• Journal of Society of Preventive Korean Medicine
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• v.22 no.2
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• pp.55-63
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• 2018

Objectives : This study was conducted to survey on the research trends of Pharmacopuncture in Korea. Methods : We searched Korean research database by using keyword 'Pharmacopuncture', 'Bee venom'. Korean research databases were Korean Studies Information Service System(KISS), Research Information Service System(RISS), National Digital Science Library(NDSL) and Korean Medicine Information System(OASIS). We classified articles identified by publish year, type of research and diseases. Results : We analyzed 533 studies. Clinical studies and non-clinical studies except literature studies were decreased from 2015. However, Literature studies had not shown particular change over the past decade. Pharmacopuncture treated disease was classified by Korean standard classification of disease(KCD), M-code (37.8%), G-code(18.4%) were frequently used. Conclusions : A variety of disease was treated by pharmacopuncture. It is necessary to increase the level of evidence of pharmacopuncture. through additional studies in the future.

• Journal of Oriental Neuropsychiatry
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• v.28 no.3
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• pp.217-230
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• 2017

Objectives: This study was conducted to review studies on somatization disorder in traditional Chinese medicine. Methods: We reviewed studies in the China National Knowledge Infrastructure (CNKI) to 2017. Keywords were 軀體化障碍, Somatization disorder, somatic symptom disorder. We included Randomized Controlled Trial (RCT), and excluded non-Randomized Controlled Trial (nRCT), non-related somatization disorder or traditional Chinese medicine, non-clinical trials, dissertations for degrees. Jadad scale and Cochrane Library's Risk of Bias (RoB) were used for assessment of the quality of studies. Results: Twelve studies were selected. The Chinese Classification of Mental Disorders-3 (CCMD-3) was most frequently used as diagnostic criteria for somatization disorder. As for outcome measurement, Hamilton Rating Scale for Depression (HAMD) was used most commonly. Meta-analysis of 10 studies revealed effective rate of Chinese Herbal Medicine groups (CHM) was significantly higher than Western Medicine groups (WM) (RR: 1.14, 95% CI: 1.02 to 1.27, p=0.02, $I^2=40%$). There was no significant difference in effective rate of CHM+WM and WM (RR: 1.12, 95% CI: 0.84 to 1.49, p=0.46, $I^2=83%$). And also, effective rate of Acupuncture group (Acu) revealed no significant difference compared to that of WM (RR: 1.17, 95% CI: 0.95 to 1.44, p=0.13, $I^2=84%$). For HAMD, there was significant difference in CHM vs, WM group and Acu vs. WM group. Quality of selected 12 RCTs was low. Conclusions: Therapies practiced in traditional Chinese medicine may be effective options for somatization disorder. treatment. For further clinical studies in Korean medicine, this study could be groundwork for development of diagnosis and treatment on somatization disorder.

• Korean Journal of Plant Resources
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• v.19 no.1
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• pp.174-179
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• 2006

A cDNA library was constructed from leaf samples of 4-year-old Panax ginseng cultured in a field. 3,000 EST from a size selected leaf cDNA library were analyzed. The 349 of 2,896 cDNA clones has related with energy metabolism genes. The 349 known genes were categorized into nine groups according to their functional classification, aerobic respiration(48.4%), accessory proteins of electron transport and membrane associated energy conservation(17.2%), glycolysis and gluconeogenesis(3.4%), electron transport and membrane associated energy conservation(2.9%), respiration(2.0%), glycolysis methylglyoxal bypass(1.7%), metabolism of energy reserves(0.6%) and alcohol fermentation(0.3%).

• Journal of the Korean Society for Library and Information Science
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• v.53 no.2
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• pp.223-246
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• 2019

This research makes the metadata element design for Korean medicine research data management and re-use. Derived metadata elements are verified in research data of Korea Institute of Oriental Medicine. TTAK.K0-10.0976 Standard, DataCite metadata Schema and National Research Data Platform of KISTI were analyzed to derive the metadata elements. Including Identifier, 27 elements were derived as top-level elements with 29 mandatory elements, 13 recommended elements and 31 optional elements. The degree of elements' necessity and new metadata elements were investigated and suggested in the survey by six domain experts in korean medicine field. In this study subject classification for the korean medicine research data are suggested. The final version of metadata schema was tested and verified by comparing with the legacy metadata fields. The research results can be used to describe the Korean medicine research data: items and files.

• Korean Journal of Acupuncture
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• v.37 no.4
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• pp.231-244
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• 2020

Objectives : This study was conducted to introduce the types and contents of books related to acupuncture published in North Korea that can be identified in South Korea, and to understand the general characteristics of North Korean acupuncture. Methods : Firstly, we identified books related to acupuncture in the Information Center on North Korea of the National Library of Korea. Specialized books on treatment interventions such as acupuncture, moxibustion, cupping, electrotherapy, and manual therapy including acupressure which stimulate acupoints were included in the study. Two authors reviewed the title, table of contents, and contents of each book in the order of publication year for the searched books. Based on this, the characteristics and trends of North Korean acupuncture were comprehensively examined. Results : The included 18 books were published between 1964 and 2018. One of them was considered a Chinese book translated into Korean and published in China, and another was a North Korean book republished by a South Korean publisher. Except for these, all were published in North Korea, two of which were translations of Chinese books. Most of them were books on the theory and clinical applications of acupuncture, but some of them focused on specific treatment interventions such as auricular acupuncture, fire needling, manual therapy, cupping, or electrotherapy. Also, there was a book about the mechanism of acupuncture analgesia in a neurophysiological way. Conclusions : Since the mid-1960s, North Korea has been steadily attempting to combine acupuncture and Western medicine by applying the disease name and classification system of Western medicine, using modern diagnostic technique, and explaining the mechanism of acupuncture based on the latest research. After the 2000s, the standard international acupuncture nomenclature by World Health Organization was used. In recent years, there has been a tendency to publish and widely disseminate specialized books on non-pharmacological treatment such as cupping, electrotherapy, and fire needling.

• Korean Journal of Acupuncture
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• v.34 no.4
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• pp.191-208
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• 2017

Objectives : The purpose of this study was to analyze the trend of pharmacopuncture in Korean patent in order to establish database for patent technology. Methods : Electronic literature searches for Korean patents related to pharmacopuncture were performed in two electronic databases (Korea Intellectual Property Right Information Service and National Digital Science Library) to June 2017. Patents that were not Korean ones, did not use medicinal herb, only described method of manufacture, or had nothing to do with pharmacopuncture were excluded in this study. The status and application date of patents, Medicinal herb, target diseases, International Patent Classification (IPC), model of experiment and extracting methods were analyzed. Results : A total of 379 patents were retrieved. Based on our inclusion/exclusion criteria, 297 patents were excluded. Of 82 included patents, 27 patents did not include experiments using pharmacopuncture, and 9 patents were invented for treating animals such as pig or calf. In IPC analysis, Bee Venom, Panax (ginseng), Angelica, and Paeoniaceae were used frequently. Musculoskeletal diseases were the most targeted diseases followed by nervous diseases. For extracting, hot water extraction, distillation extraction, and solvent extraction using alcohol, ethanol, or methanol for solvent were commonly used. Conclusions : These data are useful for inventing new patent and extending range of pharmacopuncture in clinical use, however, more systematically analyzed patent studies and pharmacopuncture-related studies for new application on various diseases are needed in further studies.

• Journal of the Korean Society for Library and Information Science
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• v.52 no.3
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• pp.193-214
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• 2018

This study aims to analyze enactment of China's old and rare books management. For the purpose, the review on China's legal system and management related to old and rare books were studied. And this study investigated 4 laws, 6 administrative regulations, 4 sector regulations, and 13 administrative normativity papers. Among those, 5 major sources for old and rare books management were identified as follows : 1) China's National Civilization Protection Law in 2013, 2) China's Old and Rare Book Organization Directive in 1989, 3) Regulation on Management of Research, Organization, and Publication of Old and Rare Books in 1986, 4) Standards on Grading Classification of Civilization Collections in 2001, and 5) Provisional Regulation on Civilization Auctioning in 2003. Based on the analysis of these sources, this study deduced implications in terms of Chinese old and rare books management such as the necessity to give considerations to 1) the importance of old and rare books management policy, 2) nationwide old and rare books management, 3) expansion of eduction and training of human resources, 4) establishment of institution specializing in old and rare books, and 5) special management of science of Chinese medicine.