• Genomics & Informatics
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• 제10권1호
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• pp.1-8
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• 2012

Recently, the technologies of DNA sequence variation and gene expression profiling have been used widely as approaches in the expertise of genome biology and genetics. The application to genome study has been particularly developed with the introduction of the nextgeneration DNA sequencer (NGS) Roche/454 and Illumina/ Solexa systems, along with bioinformation analysis technologies of whole-genome $de$ $novo$ assembly, expression profiling, DNA variation discovery, and genotyping. Both massive whole-genome shotgun paired-end sequencing and mate paired-end sequencing data are important steps for constructing $de$ $novo$ assembly of novel genome sequencing data. It is necessary to have DNA sequence information from a multiplatform NGS with at least $2{\times}$ and $30{\times}$ depth sequence of genome coverage using Roche/454 and Illumina/Solexa, respectively, for effective an way of de novo assembly. Massive shortlength reading data from the Illumina/Solexa system is enough to discover DNA variation, resulting in reducing the cost of DNA sequencing. Whole-genome expression profile data are useful to approach genome system biology with quantification of expressed RNAs from a wholegenome transcriptome, depending on the tissue samples. The hybrid mRNA sequences from Rohce/454 and Illumina/Solexa are more powerful to find novel genes through $de$ $novo$ assembly in any whole-genome sequenced species. The $20{\times}$ and $50{\times}$ coverage of the estimated transcriptome sequences using Roche/454 and Illumina/Solexa, respectively, is effective to create novel expressed reference sequences. However, only an average $30{\times}$ coverage of a transcriptome with short read sequences of Illumina/Solexa is enough to check expression quantification, compared to the reference expressed sequence tag sequence.

• 축산식품과학과 산업
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• 제8권1호
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• pp.74-77
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• 2019

• 한국고분자학회지:고분자과학과기술
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• 제21권3호
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• pp.228-235
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• 2010

• 건축사
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• 통권655호
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• pp.18-21
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• 2023

• 한국문헌정보학회지
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• 제53권4호
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• pp.73-93
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• 2019

본 연구는 학위논문의 납본과 관련한 대학도서관의 인식 및 실태를 실증적으로 분석하고 학위논문 납본의 저해요인 확인을 통해 국회도서관의 학위논문 납본 활성화 방안을 모색하였다. 분석 결과, 대부분의 대학에서는 학위논문의 납본을 수행하고 있으나, 학위논문을 담당하는 전담부서나 전담인력 배치는 저조한 것으로 나타났다. 사서들은 여러 기관으로의 납본 등 납본업무의 중복으로 인한 어려움에 직면하고 있으며, 납본이 이루어지지 않는 경우 대학도서관의 정책, 납본 절차의 중복 및 번거로움, 저작권 동의서 확보의 한계 등이 주된 이유로 나타났다. 이러한 학위논문 납본에서의 문제를 해결하고 학위논문이 지닌 사회적, 정보적 가치를 극대화하기 위한 방안으로 독립적인 납본법의 제정을 통한 디지털 학위논문 납본 제도의 강화, 디지털 학위논문의 효율적 보존 방안 마련, 통합된 학위논문 납본 시스템 개발, 석박사학위논문 전문 컬렉션 개발을 통한 국회도서관의 위상 강화 등을 제안하였다.

• 대한지리학회지
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• 제47권5호
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• pp.718-734
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• 2012

이 연구는 지역균열이라는 우리나라의 정치 현실이 국회의원선거구 획정에 개입되었는지를 확인하고, 그에 따른 문제점을 게리맨더링과 투표 등가치성을 중심으로 분석하였다. 제헌의회 이래 국회의원선거구 획정에서 게리맨더링과 투표 등가치성 훼손에 대한 논란은 지속되었고, 더욱이 소선거구 단순다수제 체제로 인해 선거구 획정이 선거 결과와 공정성에 큰 영향을 주고 있다. 특히 제18대와 제19대 총선의 선거구 획정은 부당한 지역균열정치의 간섭이 이루어진 것으로 의심되는데, 지역 그리고 선거구별 인구규모에 비해서 새누리당이 우세한 영남과 민주통합당이 우세한 호남에서 선거구 수는 최대한 확보되었고, 반면 경기도를 비롯한 다른 지역에서는 선거구 증설이 억제되었다. 이처럼 양당이 서로 확실하게 우세한 지역의 기득권을 보장해 주고, 불확실한 지역에서만 제한적으로 경쟁하는 구조의 선거구 획정은 게리맨더링에 담합한 것이라고 할 수 있으며, 결과적으로 투표 등가치성이라는 선거의 평등원칙과 헌법적 가치가 훼손되었다.

• 대한조선학회논문집
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• 제57권3호
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• pp.160-167
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• 2020

A two-stroke diesel engine and a propeller normally adopted in large merchant ships are regarded as major ship vibration sources. They are directly connected and generate various excitation components proportional to the rotating speed of diesel engine. Among the components, the magnitude of two excitation components with the same frequency generated by both engine and propeller can be compensated by the adjustment of their phase difference. It can be done by the optimization of propeller assembly angle but requires a number of burdensome trials to find the optimal angle. In this paper, the efficient estimation method to determine optimal propeller assembly angle is proposed. Its application requires the axial vibration measurement in sea trial and the numerical vibration analysis for propulsion shafting which can be substituted by additional vibration measurement after one-trial modification of propeller assembly angle. In order to verify the validity of the proposed method, the phase difference between two fifth order excitation components generated by both diesel engine and propeller of a real ship is calculated by the finite element analysis and its result is indirectly validated by the comparison of axial vibration responses at intermediate shaft obtained by the numerical analysis and the measurement in sea trial. Finally, it is numerically confirmed that axial vibration response at intermediate shaft at a resonant speed can be decreased more than 87 % if the optimal propeller assembly angle determined by the proposed method is applied.

• Nuclear Engineering and Technology
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• 제52권5호
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• pp.1022-1028
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• 2020

One of the possible options for spent-fuel management in Korea is pyroprocessing, which is a process for electrochemical recycling of spent nuclear fuel. Nuclear material accountancy is considered to be a safeguards measure of fundamental importance, for the purposes of which, the amount of nuclear material in the input and output materials should be measured as accurately as possible by means of chemical analysis and/or non-destructive assay. In the present study, a neutron measurement system based on the fast-neutron energy multiplication (FNEM) and passive neutron albedo reactivity (PNAR) techniques was designed for nuclear material accountancy of a spent-fuel assembly (i.e., the input accountancy of a pyroprocessing facility). Various parameters including inter-detector distance, source-to-detector distance, neutron-reflector material, the structure of a cadmium sleeve around the close detectors, and an air cavity in the moderator were investigated by MCNP6 Monte Carlo simulations in order to maximize its performance. Then, the detector responses with the optimized geometry were estimated for the fresh-fuel assemblies with different ²³⁵U enrichments and a spent-fuel assembly. It was found that the measurement technique investigated here has the potential to measure changes in neutron multiplication and, in turn, amount of fissile material.

• 한국군사과학기술학회지
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• 제25권6호
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• pp.561-571
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• 2022

An optical mirror assembly is an opto-mechanically coupled system as the optical and mechanical behaviors interact. In the assembly, a flexure mount attached to an optical mirror should be flexible in the radial direction, but rigid for the remaining degrees of freedom for supporting the mirror rigidly and suppressing the wavefront error of the optical mirror. This work presents an optimal design of the flexure mount using topology optimization with thermal stress constraint. By simplifying the optical mirror assembly into finite shell elements, topology optimization model was built for efficient design and good machinability. The stress at the boundary between the optical mirror and the mount together with the first natural frequency were applied as constraints for the optimization problem, while the objective function was set to minimize the strain energy. As a result, we obtained the optimal design of the flexure mount yielding the improved wavefront error, proper rigidity, and machinability.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2023년도 춘계학술발표대회
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• pp.154-155
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• 2023

WebAssembly(Wasm)은 웹에서 네이티브에 가까운 속도로 실행 가능하고, 고성능 어플리케이션의 구현도 가능하기 때문에 브라우저 및 기타 플랫폼에서 활발히 사용되고 있다. 이로 인해 Wasm에 대한 보안성이 대두되고 있는데, 이때 취약점을 탐지하는 Fuzzing 기법을 적용한 연구들이 있다. Fuzzing 기법에 대한 분류 및 대표적인 도구를 소개하고 각 기법 간 차이점 및 한계점과 향후 연구 방향을 제시한다.