• Title/Summary/Keyword: Nasopharyngeal

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A Case of Nasopharyngeal Cancer in the Sister. (자매에 발생한 비인강악성종양 1례)

  • 심윤상;양훈식;정완교
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1981.05a
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    • pp.11.4-12
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    • 1981
  • Some reports pointed out that the nasopharyngeal cancer presents not only various symptoms and signs due to the anatomical characteristics of the nasopharynx but also poor prognosis in the cases which are detected in advanced stage. This malignant tumor is not common than that of the other area, and is quite different incidence according to the geographical area and races. The oriental people especially southern Chinese have a high incidence and it was also reported to occur in the family. Recently authors had experienced a case of nasopharygeal cancer in the sister and report with review of literatures.

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Comparison of Treatment Compliance and Nutritional Outcomes among Patients with Nasopharyngeal Carcinoma with and without Percutaneous Endoscopic Gastrostomy during Chemoradiation

  • Peerawong, Thanarpan;Phungrassami, Temsak;Pruegsanusak, Kovit;Sangthong, Rassamee
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5805-5809
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    • 2012
  • Aims: The study aimed to compare treatment compliance and nutritional outcomes in nasopharyngeal carcinoma (NPC) patients during chemoradiation. Methods: Clinical information of patients with NPC that underwent chemoradiation during 2004-2009 were retrieved from the hospital database and retrospectively reviewed. Patients were categorised into a prophylactic percutaneous endoscopic gastrostomy (PPEG) group and a non-PPEG group. Clinical information including treatment compliance, weight, haematological and renal toxicity was compared. Results: A total of 219 patients were reviewed and categorised into PPEG (n=77) and non-PPEG (n=142). Significant differences in absolute percentage weight loss between groups were found from the $3^{rd}$ cycle of chemotherapy. There were 24.2, 20.3 and 24.8% in the third, the fourth and the fifth cycles of chemotherapy, respectively. Migration of grade 2 to grade 3 weight loss was obviously seen in the $3^{rd}$ cycle as well. A significant difference of grade 3 or more hypokalemia was found with values of 14.3% and 50% in the PPEG and non-PPEG groups, respectively. Other toxicity parameters and treatment compliance were not different between the groups. Conclusions: Use of PPEG resulted in decreased severe weight loss, reduced migration from grade 2 to grade 3 weight loss and reduced hypokalaemia. However, benefits in treatment compliance could not be detected. So consideration of PPEG in NPC patients requires care.

Acute Toxicity in Nasopharyngeal Carcinoma Patients Treated with IMRT/VMAT

  • Ozdemir, Sevim;Akin, Mustafa;Coban, Yasin;Yildirim, Cumhur;Uzel, Omer
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.5
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    • pp.1897-1900
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    • 2015
  • Purpose: To evaluate acute toxicity in nasopharyngeal cancer (NPC) patients treated with intensity modulated radiotherapy (IMRT)/volumetric modulated arc therapy (VMAT) with or without cisplatin-based chemotherapy. Materials and Methods: A total of 45 newly diagnosed, histologically proven non-metastatic NPC patients treated with IMRT between May 2010 and December 2012, were evaluated retrospectively, 37 planned with Eclipse and 8 with Prowess Panther treatment planning system. The doses to the planning target volumes of primary tumor and involved lymph nodes, high risk region, and uninvolved regional nodal areas were 70 Gy, 60 Gy, and 54 Gy respectively and delivered simultaneously over 33 fractions to 39 patients. Another 6 patients irradiated with sequential boost technique. Some 84.4% of patients received chemotherapy. Acute toxicities were graded according to the Radiation Therapy Oncology Group scoring criteria and Common Terminology Criteria for Adverse Events (CTCAE) for chemotherapy side effects. Results: Median age was 43 years (14-79) and all patients were WHO type II. Grade 1 mucositis and dysphagia were observed in 17 (37.8%), and 10 (22.2%) patients, respectively. The incidence of acute grade 2 mucositis and dysphagia was 55.6% and 68.9%, respectively. The most common chemoradiotherapy related acute toxicities were nausea, leucopenia and thrombocytopenia. Grade 3 toxicity was detected in 13 (28.8%) cases. No grade 4 toxicity was occurred. Mean weight loss was 9%. None of the patients required the insertion of percutaneous endoscopic gastrostomy for nutritional support. Radiation therapy was completed without interruption in all patients. Conclusions: IMRT is a safe and effective treatment modality, and well tolerated by patients in the treatment of nasopharyngeal carcinoma. No unexpected side effects were observed.

A Case of Neck Soft Tissue Infection in Patient with Nasopharyngeal Cancer; Misdiagnosed as Local Progression during External Radiotherapy (비인두암 환자에서 방사선 치료중 암의 국소진행으로 오인된 경부 연조직 감염 1례)

  • Lee So-Yeon;Im So-Hi;Choi Hyun-Cheul;Kim Sung-Hwan;Jun Jung-Soo;Back Joon-Hyun;Yoo Jin-Young;Noh He-Il;Kim Hoon-Kyo
    • Korean Journal of Head & Neck Oncology
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    • v.18 no.2
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    • pp.216-218
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    • 2002
  • A 38-year-old man, who was diagnosed nasopharyngeal carcinoma (stage T4N2Mx) had rapidly growing lower neck mass (at level IV area) with local inflammation sign during concurrent chemoradiotherapy. After we performed Color Doppler sonography and fine needle aspiration biopsy of the neck mass, we differentiated neck soft tissue infection from tumor extension. Size of the mass decreased after antibiotics therapy. It was difficult to differentiate neck infection from tumor progression during treatment in naspharyngeal carcinoma.

A Syndrome of Carotid Sinus Hypersensitivity in a Patient with Nasopharyngeal Carcinoma (비인강암 환자에서 발생한 경동맥동 과민증후군)

  • Yoon Hyung-Gue;Kang Jin-Hyung;Moon Han-Lim;Chae Jang-Seong;Kim Hoon-Kyo;Lee Kyung-Shik;Kim Dong-Jip;Lee Kwang-Soo;Yoon Sei-Chul;Cho Seung-Ho;Suh Byung-Do
    • Korean Journal of Head & Neck Oncology
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    • v.9 no.1
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    • pp.63-67
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    • 1993
  • The syndrome of carotid sinus hypersensitivity is cardovascular symptom complex including lightheadedness, transient loss of consciousness, perspiration, pallor, weakness of lower extremities, transient hypotension, bradycardia and seizure, which occurs from firing of hyperactive carotid sinus reflex. Most cases are idiopathic, but maliganant tumors involving parapharyngeal space have been occasionally implicated. We present a case of carotid sinus hypersensitivity due to nasopharyngeal carcinoma invading the parapharyngeal space with bilateral cervical lymphnode metastases(stage IV, $T_4N_2M_0$). The patient experienced several episodes of severe syncope proceeded by blurring of vision, dizziness and nausea, which were used to occur while he was working in erect position. The tumors were markedly regressed by external radiation therapy with successful resolution of syncope.

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Nasopharyngeal Polyp in a Domestic Short Hair Cat (단모종 집고양이의 코인두 폴립 증례)

  • Lee, Da-Mi;Yu, Do-Hyeon;Nho, Dong-Ho;Song, Ru-Hui;Kim, Jun-Hwan;Cho, Ho-Seong;Park, Jin-Ho;Park, Chul
    • Journal of Veterinary Clinics
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    • v.28 no.4
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    • pp.435-437
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    • 2011
  • A 2-year-old, domestic short hair cat presented because of a 2-year history of chronic nasal discharge and chronic otitis. Examination of the oral cavity revealed a mass in the nasopharynx. For further examination, computed tomography (CT) was performed and large polyp was revealed on the nasopharyngeal area. Traction removal of the polyp was performed using a spay hook. After removal of the mass, Horner's syndrome was developed but resolved spontaneously within 14 days.