• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.1631-1635
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• 2016

Helicobacter pylori infection plays an important role in the pathogenesis of chronic gastritis, peptic ulcer disease and gastric malignancy. A diagnosis of infection is thus an important part of a treatment strategy of many gastrointestinal tract diseases. Many diagnostic tests are available but all have some limitations in different clinical situations and laboratory settings. A single gold standard cannot available, but be used for diagnosis of Helicobacter pylori infection in daily clinical practice in all areas, so several techniques have been developed to give reliable results, especially focusing on real time endoscopic features. The narrow band imaging system (NBI) and high resolution endoscopy are imaging techniques for enhanced visualization of infected mucosa and premalignant gastric lesions. The aim of this article is to review the current diagnostic options and possible future developments detection of Helicobacter pylori infection.

• 대한기관식도과학회지
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• 제15권2호
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• pp.30-35
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• 2009

Lung cancer could be developed through a series of morphological changes from dysplasia to carcinoma in situ and then invasive cancer. However, precancerous lesions are generally a few cell layers thick and are detected only by chance. Autofluorescence bronchoscopy(AFB) is one of the newly developed diagnostic tools to detect the pre-cancerous lesions m the bronchial tissue. Several studies have shown that AFB improved the rate of detection of cancer and dysplastic lesions of the airway, especially those in intraepithelial stage. However, there were high rates of false positive with AFB, and it is also important to develop non-biopsy methods because of lack of accurate information of variable course of preneoplastic lesions regarding progression. So, many other technologies were developed, such as narrow band imaging(NBI), endobronchoscopic ultrasound, optical coherence tomography, and confocal fluorescence microendoscopy. Among the new machines, NBI is a new optical technology that can clearly visualize the microvascular structure m the mucosal layer. NBI seems to increase specificity without compromising sensitivity. In the future such techniques would make it possible to precisely study in detail the natural history of the premalignant epithelium.

• 천문학회보
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• 제41권1호
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• pp.52.1-52.1
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• 2016

We introduce the characteristics and performance of the 0.25m telescope at Mangpo high school Unmanned Robotic Observatory (MURO) which was established in Yangpyeong-gun, Gyeongi-do, KOREA in 2015 January. MURO system included Astrohaven 2.1m non-rotation fiberglass clamshell dome, Paramount MEII mount, Takahashi CCA 0.25m wide field telescope, FLI PL 16803 4K CCD with 7-positions filter wheel system, all sky camera and point grey wide field camera, IR 4 chanel heat sensor camera for security, DAVIS realtime weather cast, and power controled by ARS system. All control softwares are from off-the-shelf products based on Windows 7 OS to be easily operated and maintained. We expect to perform variety of science programs ranging from supernovae follow-up observation to narrow band imaging survey as well as science class activities at Mangpo high school.

• Clinical Endoscopy
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• 제51권6호
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• pp.534-540
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• 2018

From dye-assisted conventional chromoendoscopy to novel virtual chromoendoscopy, image-enhanced endoscopy (IEE) is continuously evolving to meet clinical needs and improve the quality of colonoscopy. Dye-assisted chromoendoscopy using indigo carmine or crystal violet, although slightly old-fashioned, is still useful to emphasize the pit patterns of the colonic mucosa and predict the histological structures of relevant lesions. Equipment-based virtual chromoendoscopy has the advantage of being relatively easy to use. There are several types of virtual chromoendoscopy that vary depending on the manufacturer and operating principle. IEE plays distinctive roles with respect to histologic characterization of colorectal polyps and prediction of the invasion depth of colorectal cancers. In addition, the newest models of IEE have the potential to increase adenoma and polyp detection rates in screening colonoscopy.

• Current Optics and Photonics
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• 제4권6호
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• pp.530-539
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• 2020

Hyperspectral images feature a relatively narrow band and are easily disturbed by noise. Accurate estimation of the types and parameters of noise in hyperspectral images can provide prior knowledge for subsequent image processing. Existing hyperspectral-noise estimation methods often pay more attention to the use of spectral information while ignoring the spatial information of hyperspectral images. To evaluate the noise in hyperspectral images more accurately, we have proposed a spectral-spatial cooperative noise-evaluation method. First, the feature of spatial information was extracted by Gabor-filter and K-means algorithms. Then, texture edges were extracted by the Otsu threshold algorithm, and homogeneous image blocks were automatically separated. After that, signal and noise values for each pixel in homogeneous blocks were split with a multiple-linear-regression model. By experiments with both simulated and real hyperspectral images, the proposed method was demonstrated to be effective and accurate, and the composition of the hyperspectral image was verified.

• 대한후두음성언어의학회지
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• 제33권1호
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• pp.13-19
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• 2022

Vocal fold leukoplakia poses a challenge to otolaryngologists due to its various spectrum of pathologic diagnosis. The degree of dysplasia is associated with malignancy risk and the new 2017 WHO classification system changed from the 3-tier system to a 2-tier system consisting of low and high grades. Infections including candidiasis, cryptococcosis, and tuberculosis should also be included in the differential diagnosis. Efforts have been made to evaluate risks using endoscopic technologies such as narrow band imaging, and surgery is essential for histopathological diagnosis. Regarding management, it is important to make an accurate diagnosis and find a balance between oncologic safety and functional outcome.

• Clinical Endoscopy
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• 제56권2호
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• pp.261-261
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• 2023

• 천문학회지
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• 제52권6호
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• pp.235-244
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• 2019

We present the results of near-infrared imaging observations of the galaxy overdensity around the z = 1.44 radio-loud active galactic nucleus (AGN) 6CE1100+3505, which was carried out with the purpose of sampling the redshifted Hα emission from the actively star-forming galaxies that could constitute the overdensity. The existence of the structure around this AGN was spectroscopically confirmed by previous grism observations which are however limited to the central region. Using the CH4Off narrow/medium-band and H broad band filters in the Wide Infrared Camera (WIRCam) on the Canada-France-Hawaii Telescope (CFHT), we constructed a sample of objects that show a flux excess in the CH4Off band due to line emission. The emission line flux is ~ 4.9 × 10^-16 erg s^-1 cm^-2, corresponding to a star formation rate (SFR) of ~ 50 M_⊙ yr^-1 for galaxies at redshifts z ~ 1.4. None of the galaxies with medium-band flux excess is located within 1 Mpc from the central AGN, and there is no evidence that the selected galaxies are associated with the proposed cluster. Along with the star formation quenching near the center that was found from the previous grism observations, the lack of extreme starbursts in the structure suggests that at z ~ 1.4, overdense regions are no longer favorable locations for vigorous star formation.

• 대한원격탐사학회지
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• 제35권3호
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• pp.375-387
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• 2019

드론 기반의 초분광 영상은 원격탐사 활용에 고해상도의 많은 장점을 제공한다. 본 연구의 목적은 배추의 단수 추정의 최적밴드를 선정하는 것이다. 초분광 영상은 드론에 탑재한 초분광 이미지 센서를 활용하여 403.36~995.19 nm 파장 범위를 대상으로 3.97 nm 간격으로 150개의 밴드를 수집하였으며, 배추 생체중 데이터는 2,031개의 배추를 대상으로 현장에서 직접 조사하였다. 적색, 적색경계 및 근적외 밴드를 조합하여 계산된 정규화 식생지수와 객체별 배추 생체중과의 관계를 정량적으로 비교한 결과, 697.29 nm(적색 밴드), 717.15 nm(적색경계 밴드) 및 808.51 nm(근적외 밴드)를 조합하여 산출한 식생지수가 배추의 생체중을 가장 잘 설명하는 것으로 나타났다. 본 연구를 통해 배추 생산성을 평가하는데 가시광 및 근적외 파장대에서 3개의 최적밴드를 선정하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.2765-2769
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• 2013

Background: A close association between patterns identified by magnifying narrow-band imaging (M-NBI) and histological type has been described. M-NBI patterns were also recently reported to be related to the mucin phenotype; however, detials remain unclear. Materials and Methods: We investigated the cellular differentiation of gastric cancer lesions, along with their mucosal distribution observed by M-NBI. Ninety-seven depressed-type early gastric cancer lesions (74 differentiated and 23 undifferentiated adenocarcinomas) were visualized by M-NBI. Findings were divided into 4 patterns based on abnormal microvascular architecture: a chain loop pattern (CLP), a fine network pattern (FNP), a corkscrew pattern (CSP), and an unclassified pattern. Mucin phenotypes were judged as gastric (G-type), intestinal (I-type), mixed gastric and intestinal (M-type), and null (N-type) based on 4 markers (MAC5AC, MUC6, MUC2, and CD10). The relationship of each pattern of microvascular architecture with organoid differentiation indicated by cancer cell differentiation and its distribution in each histological type of early gastric cancer was investigated. Results: All CLP and FNP lesions were differentiated. The cancer cell distribution showed organoid differentiation in 84.2% (16/19) and 61.1% (22/36) of the two types of lesions, respectively, and there was a significant difference from the unclassified pattern with organoid differentiation (p<0.001). Almost all (94.7%; 18/19) CSP lesions were undifferentiated, and organoid differentiation was observed in 72.2% (13/18). There was a significant difference from the unclassified pattern with organoid differentiation (p<0.05). Conclusions: Cellular differentiation and distribution are associated with microvascular architecture observed by M-NBI.