• Sleep Medicine and Psychophysiology
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• v.2 no.2
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• pp.146-155
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• 1995

Jet lag can be defined as the cumulative physiological and psychological effects of rapid air travel across multiple time zone. The consequences of jet lag include fatigue, general malaise, sleep disturbances, and reductions of cognitive and psychomotor performance, all of which have been documented in experimental biological and air crew personnel studies. Thus authors tried to study the jet lag of natural travellers by modified self reporting sleep log. Total 61 healthy travellers was studied for 3 days before and 7 days after jet-flights across seven to ten time zone. The eastbound travelling group was 38 persons, aged 19 -70 and westbound travelling group was 23 persons, aged 13 - 69. Sleep onset time, wake-up time, sleep latency, awakening frequency on night sleep, awakening duration on night sleep, sleepiness at wake-up and nap length were evaluated. Our results suggested that the 7 to 10 time zone shift gave significant influence to traveller's sleep-wake cycles. The date which subjective physical condition was recovered on was $5.16{\pm}1.50$ day after arrivals for eastbound, while for westbound, $4.91{\pm}1.62$ day. In eastbound travelling, sleep onset time became later than baselines and could not recover until 7th day. But in westbound, it became earlier than baseline and could recover until 6th day. The mean score of 24-hour sleepiness was greater in eastboumd than westbound. Therefore the eastbound travelling caused more sleep-wake cycle disturbance and daytime dysfunction than westbound travelling. In other parameters, there was no definite difference between east and westbound. From our results, it was suggested that the symptom severity of jet lag was dependent on the travelling direction. To demonstrate more definite evidence, large sized data collections and comparision by age difference were needed.

• Korean Journal of Plant Taxonomy
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• v.40 no.4
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• pp.267-273
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• 2010

The distribution of three typical warm-temperate evergreen trees, Quercus acuta Thunb., Neolitsea sericea (Blume) Koidz., and Machilus thunbergii Siebold & Zucc., were surveyed on the Korean Peninsula based on field and specimen investigations and the distribution maps of the three species were prepared. The distribution patterns of the species correspond to the south coast floristic region in Korea, which includes the distributional areas of Jeju-do, Isl. Ulleung, the southern coastal areas, and the areas up to the islands around Incheon in the Yellow Sea. The northernmost limit of the distribution of Quercus acuta is Isl. Nap of Incheon in the west, and a new distribution was found at Isl. Ulleung in the East Sea; additionally, the limit of Neolitsea sericea is the Deojoek archipelago of Incheon. The northernmost limit of Machilus thunbergii is Isl. Daecheong of Incheon, which is the highest latitude among those of the three species. This distribution survey of evergreen broad-leaved trees in Korea can be used as basic data for the delimitation of floristic regions and as a bio-indicator of climatic change.

• Journal of East-West Nursing Research
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• v.5 no.1
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• pp.65-74
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• 2000

This study was attempted to show basic data for search of nursing intervention about sleep improving in home and institute elderly peoples. Research design was cross-sectional survey method for comparison of sleep patterns and another variables between home and institute elderly peoples. Subjects were sampled by purpose as home and institute elderly peoples at age of 65 or older in Seoul or nearly. The survey questionnaire was used by modification of sleep questionnaire which Kim, O, Song & Bak(1997) developed. Data were collected between December, 1999 and April, 2000. And data were analyzed by SPSS PC+ for purpose of research. Results are as follows: 1. Home and institute elderly peoples, all were change of sleep patterns and sleep pattern was showed early sleeping down. But institute elderly peoples slept earlier than home elderly peoples. 2. As rest of morning, difficulty of falling asleep and disturbance of re-asleep, subjective thinking and feeling were showed more negative thing home elderly peoples than institute elderly peoples. As frequency of falling asleep within 5 min in 1 week, frequency of falling asleep over 30 min in 1 week and frequency of awakening in a day, objective frequency were showed more insomnia institute elderly peoples than home elderly peoples. Home elderly peoples didn't nap most and institute elderly peoples napped on very short time. 3. Regarding sleep-disturbing factors, physical factor was popularly joint-disturbance in all, home and institute elderly peoples. Environmental factor was popularly noise, particularly institute elderly peoples. Emotional factor wasn't all. 4. Practiced strategies for better sleep was popularly TV/Radio in home elderly peoples and were popularly regular sleep and religious action in institute elderly peoples. From the results of this study, home elderly peoples need nursing intervention of improving self-satisfaction on sleep and institute elderly peoples need nursing intervention of decreasing falling asleep-disturbing and decreasing frequency of awakening in sleep.

• Korean Journal of Plant Resources
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• v.17 no.3
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• pp.289-296
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• 2004

A cDNA clone (GenBank accession no. CF924621) homologous to aluminum induced protein gene was isolated and characterized from Codonopsis lanceolata (ClAIP). The ClAIP is 906 nucleotides long and has an open reading frame of 711 bp with a deduced amino acid sequence of 236 residues. The ClAIP shows high homology to A. marina (84%), G. hirsutum(83%), V. radiata (83%), A. thaliana (80%), B. nap us (78%) and T. aestivum (68%). The deduced amino acid sequence of ClAIP also has homology to the N-terminal end of plant Asn synthetase. This region does not contain the active sites of the enzyme and the significance of this conservation is currently not clear. To investigate the expression of ClAIP against several heavy metal stresses, we treated the sliced tap root of C. lanceolata with various heavy metals. The expression of ClAIP was increased by 25 uM $Al_2$(SO$_3$)$_4$ in proportion to incubation time and also increased by 50 uM CdCl$_2$.

• Journal of Microbiology and Biotechnology
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• v.31 no.7
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• pp.999-1010
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• 2021

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the environment. They are highly toxigenic and carcinogenic. Probiotic bacteria isolated from fermented foods were tested to check their ability to degrade and/or detoxify PAHs. Five probiotic bacteria with distinct morphologies were isolated from a mixture of 26 fermented foods co-cultured with benzo(a)pyrene (BaP) containing Bushnell Haas minimal broth. Among them, B. velezensis (PMC10) significantly reduced the abundance of BaP in the broth. PMC10 completely degraded BaP presented at a lower concentration in broth culture. B. velezensis also showed a clear zone of degradation on a BaP-coated Bushnell Haas agar plate. Gene expression profiling showed significant increases of PAH ring-hydroxylating dioxygenases and 4-hydroxybenzoate 3-monooxygenase genes in B. velezensis in response to BaP treatment. In addtion, both live and heat-killed B. velezensis removed BaP and naphthalene (Nap) from phosphate buffer solution. Live B. velezensis did not show any cytotoxicity to macrophage or human dermal fibroblast cells. Live-cell and cell-free supernatant of B. velezensis showed potential anti-inflammatory effects. Cell-free supernatant and extract of B. velezensis also showed free radical scavenging effects. These results highlight the prospective ability of B. velezensis to biodegrade and remove toxic PAHs from the human body and suggest that the biodegradation of BaP might be regulated by ring-hydroxylating dioxygenase-initiated metabolic pathway.

• Tuberculosis and Respiratory Diseases
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• v.42 no.1
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• pp.84-92
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• 1995

Background: Nasal applied continuous positive airway pressure(CPAP) is a highly effective method of treatment for obstructive sleep apnea syndrome. More than a decade of accumulated experience with this treatment modality confirmed that it is unquestionably the medical treatment of choice for patients with obstructive sleep apnea syndrome. However it takes long time to reach optimal CPAP pressure. To save the time to reach optimal pressure, it is necessary to clarify the time to reach optimal pressure for treatment of obstructive sleep apnea syndrome. Method: CPAP pressure is titrated during an overnight study according to a standardized protocol. Just before the presleep bio-calibration procedures, the technician applies the nasal mask and switches on the clinical CPAP unit. Initial positive for pressure is typically 3.0 centimeters of water pressure. After sleep onset, the technician gradually increases the pressure until sleep-disordered breathing events disappear or become minimal. The pressure must maintain maximal airway patency during both NREM and REM sleep to be considered effective. Before recommending a final pressure setting, sleep recording and oximetry data are reviewed by an American Board of Sleep Medicine certified Sleep Specialist and a Registrered Polysomnographic Technologist. Results: We examined the time required to reach optimal pressure during routine CPAP titration in 127 consecutively evaluated individuals diagnosed with sleep-disordered breathing. Results indicate that 33% of patients required more than four hours to attain satisfactory titration. This indicates that a four-hour session is marginally enough time, at best, to determine a proper CPAP pressure setting. Moreover, 60 of 127 patients required further adjustment after optimal pressure was reached. These additional pressure trials were needed to confirm that higher pressures were not superior for eliminating sleep-disordered breathing events. Conclusions: The data presented underscore the logistical difficulty of titrating CPAP during split-night studies without modifying the titration procedure. Futhermore, the time needed to reach optimal pressure makes it improbable that proper CPAP titration can be performed during a 2-3 hour nap study.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.6
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• pp.642-649
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• 2016

This study examined the meaning of instructional materials by observing the daily work of an infant class in a daycare center to make some suggestions on the accreditation and evaluation of instructional materials for early childhood education and educare. Ethnography was chosen to determine in detail what the instructional materials meant for the selected preschoolers. The activities that belonged to each area of free optional activities and made use of instructional materials were observed, and the eating time, nap time, and outdoor play were all observed. The data were gathered by visiting the selected daycare center. A participant observation and teacher interviews were conducted, and notes were taken on the spot. When their verbal expressions and nonverbal expressions needed to be observed owing to their unique characteristics, a camcorder was used to record their words to have a more profound understanding of them. All the collected data that included this researcher's observation note, the teacher interview data, the standard childcare curriculum manual, the daycare center's yearly, and the daily childcare plans and curriculum evaluation data were classified and categorized by performing an inductive analysis. As a result, the instructional materials had three meanings for the infants. The first was "friends who welcomed them and whom they could play with.' The second was "a cozy nest," and the third was "another teacher." Given the findings of the study, the preparation of standards for instructional materials for infants in childcare facilities is required, and even equipment that is used as instructional materials should be taken into consideration when instructional materials for infants are accredited.

• Sleep Medicine and Psychophysiology
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• v.11 no.2
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• pp.80-83
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• 2004

Objectives: The multiple sleep latency test (MSLT) is commonly used as a valid objective measure of sleepiness. The procedure of MSLT is well standardized but the sleep onset criterion is somewhat variable. One epoch of stage 1 sleep is the most commonly used criterion, and the criterion of three epochs of stage 1 sleep is also used. The purpose of this study was to compare the two criteria used to determine sleep onset. Methods: We retrospectively analyzed 60 consecutive MSLT that were performed according to a standaridized protocol. We scored each test using the two different criteria for sleep onset and then statistically analyed the results. Results: Using the different criteria, 20 patients among 60 showed changes in mean sleep latency (33.3%). The extent of change ranged from 1.3% to 38.5% (mean 15.9%). Non-narcoleptic patients showed a significantly higher incidence of change than other sleep disorder patients. Conclusion: Changes in mean sleep latency occurred according to the different criteria of sleep onset. But the difference arising from different criteria was statistically not significant in patients with moderate to severe sleepiness. Considering that 1 epoch criterion for sleep onset is more sensitive in detecting clinically significant sleepiness, the authors suggest that the 1 epoch criterion is more reliable than the 3 epochs criterion.

• Analytical Science and Technology
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• v.25 no.6
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• pp.421-428
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• 2012

In this study, PCDD/PCDFs, PAHs and PCBs in wastes from metal, plastic and wastewater treatment facilities were analyzed. The concentrations of PCDD/PCDFs ranged from 7.37~432.20 ng-TEQ/kg in fly ash, 0.51~855.01 ng-TEQ/kg in incinerated ash and 0.37~385.81 ng-TEQ/kg in dust. Dioxin content was lower, compared to data in foreign countries. PAHs concentration was in the range of 0.0075~2.9225 mg/kg for process sludge and 0.0035~1.6716 mg/kg for wastewater sludge, which satisfied all of the two standards (Nap, Ant, B(a)F:4/0.8, Phen, B(a)A:5/1, Flt:10/2.5, B(a)P:4.5/0.9) of the Marine Environment Management Act. PAHs concentration in process sludge and wastewater sludge were slightly lower than those abroad. According to the analysis of seven types of PCBs (in comparison with the first standard, 0.15 mg/kg), concentration was found in the range of 0.0~0.65 mg/kg, while PCB-52, PCB-101, PCB-138, PCB-153 and PCB-180 isomers were detected in excessive value in some machine oil and hydraulic fluid.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.4B
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• pp.343-352
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• 2011

The water quantity by intake station as well as the tributary flow discharge acting as sink or source were added to the main flow rate in the present study and RMA-2 and RMA-4 models were applied to the reach from Pal-dang dam to Jam-sil submerged weir to investigate the influence of water supply withdrawal on the river flow and water quality. The numerical results revealed that the water supply withdrawal from 5 intake stations located upstream of Jam-sil submerged weir changed the total flow rate and therby induced different hydraulic characteristics in terms of water surface elevation and velocity. The changed flow field by the inclusion of water intake quantity led to the variation of water quality. By the consideration of the water supply withdrawal, the velocity structure was significantly disturbed by the outflowing flow condition nearby Gu-ui, Ja-yang, and Pung-nap intake stations. Furthermore, the mean velocity was lowered by 25% and the stage upstream of Gu-ui station rose upto 1.5 cm compared with the result by exclusion of water intake. In case of no water withdrawal, the distribution of BOD concentration was parallel throughout the domain. However, when the water withdrawal is considered, the distribution of BOD concentration nearby the Gu-ui, Am-sa, and Ja-yang station was signifiantly changed. In addition, the BOD concentration including the intake stations showed higher value at the downstream of the reach due to the loss of the discharge by water withdrawal effect. It is concluded that both the inflow and outflow discharges from tributaries and water intake stations should be included in the numerical simulation to analyze the hydrodynamic behaviors and mixing characteristics more accurately.