• Title/Summary/Keyword: Nakai

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The Pharmacognostical Studies on Tang-gwi (국산 당귀의 생약학적 연구)

  • 한대석
    • YAKHAK HOEJI
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    • v.6 no.1
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    • pp.21-24
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    • 1962
  • A report is given of microscopic study of the root Angelica gigas Nakai comparing with Ligusticum acutilobum S. et Z.(=Angelica acutiloba Kitagawa). The following characteristics are outstanding. 1. Angelica gigas Nakai is more tender and softer than Ligusticum acutilobum S. et Z. 2. Both Angelica gigas Nakai and Ligusticum acutilobum S. et Z. are alike in the form and arrangement of fundamental parenchyma in cortex and xylem. 3. No mechanical tissues are present but the substitute fibers in the Angelica gigas Nakai and Ligusticum acutilobum S. et Z. 4. The intercellular space are more numerous and larger in Angelica gigas Nakai than in Ligusticum acutilobum S. et Z. 5. Secretory tissue in Angelica gigas Nakai consists of numerous canals while in Ligusticum acutilobum S. et Z. very few.

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Pharmacognostical Studies on the 'O Ga Pi Ip' (오가피잎의 생약학적 연구)

  • Lee, Eun-Sook;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.37 no.1 s.144
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    • pp.1-10
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    • 2006
  • 'O Ga Pi Ip' has been used in Korea to cure rheumatism, neuralgia, edema, dematopathy, and impotence. The botanical origin of the crude drug has not been confirmed pharmacognostically. To clarify the botanical origin of 'O Ga Pi Ip', the morphological and anatomical characteristics of the leaves of Acanthopanax species growing in Korea and Japan, A. chi-isanensis Nakai, A. Koreanum Nakai, A. rufinerve Nakai, A. senticosus (Rupr.et Maxim). Harms, A senticosus (Rupr.et Maxim.) for inermis Harms, A. seoulense Nakai, A sessiliflorus (Rupr. et Maxim.) Seem, A. divaricatus Seem, A. sieboldianum Makino were compared. As a result, it was determined that 'O Ga Pi Ip' was the leaf of A. sessiliflorus (Rupr. et Maxim.) Seem, A chiisanensis Nakai, and A. koreanum $Nakai_I$.

Effects of Cirsium setidens nakai on In Vitro Growth and Osteogenic Differentiation of Human Bone-Derived Mesenchymal Stem Cells

  • Kim, Hye-Been;Cheong, Kyu Min;Seo, Yu Ri;Lim, Ki-Taek
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 2017.04a
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    • pp.109-109
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    • 2017
  • Cirsium setidens nakai belonging to cirsium has been reported to have various physiological activities including anticancer activity because it contains polyphenols, dietary fiber, minerals and vitamins. Despite these positive positive efficacies, however, no studies have studied cirsium setidens nakai products as biomaterials such as cellular metabolism and bone formation. Thus, the aim of this study was evaluate of osteogenesis differentiation a natural material extracted from cirsium setidens nakai. The natural materials in this studys in this studywere created by 40% ethanol extraction process and then dried. FabricatedFabricatedpowders were added to a medium at various concentrations (0.01, 0.05, 0.1, 0.2, and $0.25{\mu}g/mL$), and pure medium was used as a control. The natural material caused positive increases in cell metabolic activity and mineralized bone formation without cytotoxicity. In addition, we observed higher expression of genes such as ALP, BSP, Runx2 and COL1 in cirsium setidens nakai treatment cells. As a result, this study produced and investigated cirsium setidens nakai extracts and the natural materials showed potential biomaterials. In this research indicated that the cirsium setidens nakai extracts might have promising applications in areas of agricultural, biological and food engineering as a biomaterial.

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Quality Characteristics of Cookies Prepared with Angelica gigas Nakai Powder (당귀분말을 첨가한 쿠키의 품질특성)

  • Choi, Suk-Hyun
    • Culinary science and hospitality research
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    • v.15 no.2
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    • pp.309-321
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    • 2009
  • This study was conducted the physicochemical and sensory characteristics of cookies added with Angelica gigas Nakai powder(0~2.5%). The pH of the samples ranged from 6.13 to 6.27, and the density ranged from 0.99 to 1.15. Increasing the amount of Angelica gigas Nakai powder in the cookies decreased the spread factor of the cookies and tended to decrease lightness(L) and yellowness(b) in the Hunter color value with redness(a) increased. For the textural characteristics, the addition of Angelica gigas Nakai powder increased strength and hardness. The sensory evaluation showed that the cookies with Angelica gigas Nakai powder were preferred more than those without in color, odor, texture, taste and overall preference. Especially, cookies with 1.5% of Angelica gigas Nakai powder were valued as best.

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Type Specimens and Lectotypification of Nakaian Taxa from Ulleung Island, Korea (Nakai에 의해 기재된 울릉도산 분류군의 기준표본 및 선정기준표본 설정)

  • Shin, Hyunchur;Kim, Young-Dong
    • Korean Journal of Plant Taxonomy
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    • v.37 no.4
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    • pp.503-527
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    • 2007
  • Type specimens (deposited at TI) for 55 Nakaian taxa described from Ulleung Island were examined. Four taxa of those were confirmed as simple name combinations. Excluding 15 taxa which have already been lectotypified, lectotypes for 25 taxa including Arabis takesimense Nakai, Fagus multineruis Nakai, and Salix ishidoyana Nakai were designated in here. Validity of publication for the names of five taxa was not confirmed here. Type specimens for the remaining six taxa need further examination.

Effects of Angelica gigas Nakai diet on lipid metabolism, alcohol metabolism and liver function of rats administered with chronic ethanol (당귀의 첨가 식이가 흰쥐의 지방대사와 알콜대사 및 간기능에 미치는 영향)

  • Cha, Youn-Soo;Choi, Dong-Seong;Oh, Suk-Heung
    • Applied Biological Chemistry
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    • v.42 no.1
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    • pp.29-33
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    • 1999
  • To investigate the effects of Angelica gigas Nakai diet on lipid metabolism, alcohol metabolism and liver function of rats administered with chronic ethanol, Sprague-Dawley male rats were fed either AIN-76 diet (control), control diet with ethanol, control plus Angelica gigas Nakai diet, or control plus Angelica gigas Nakai diet with ethanol for 30 days. On the 21st day, all of the rats were given an oral dose of ethanol and blood-ethanol concentration was monitored for the next 5 hours. The results obtained were: 1) Upon ethanol administration, the blood ethanol concentration was decreased from 2 hr significantly in the group of control plus Angelica gigas Nakai diet compared with control diet group; 2) The blood ethanol oxidation rate was increased in the group of control plus Angelica gigas Nakai diet with ethanol compared with control diet group or control plus Angelica gigas Nakai diet group. After 30 days, rats were sacrificed and then lipid and enzyme determinations in blood and liver were carried out. The results obtained were: 1) LDL-cholesterol in the blood of control plus Angelica gigas Nakai diet group was decreased significantly compared with control diet group; 2) Angelica gigas Nakai diet decreased liver triglyceride and total lipid and blood ${\gamma}-GTP$ level increased due to the chronic ethanol administration. These data suggest that Angelica gigas Nakai can have a recovery function on the symptoms of alcohol related diseases.

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The Specific Plant Species and Naturalized Plants in the Area of Naejangsan National Park, Korea (내장산국립공원 일대의 특정식물과 귀화식물)

  • Lee, Hee-Cheon;CheKar, Eun-Key;Lim, Dong-Ok
    • Korean Journal of Environment and Ecology
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    • v.25 no.3
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    • pp.267-283
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    • 2011
  • Endangered species designated by The Ministry of Environment in region of Naejangsan National Park were found Lycoris chinensis var. sinuolata K.H.Tae & S.T.Ko, Iris koreana Nakai, Cymbidium macrorrhizum Lindl and Vexillabium yakushimensis (Yamam.) F.Maek.(4 taxa). The floristic special plants were recorded to a total of 159 taxa; that is, class I species (91 taxa) were containing as Chloranthus fortunei (A.Gray) Solms, Vicia anguste-pinnata Nakai and Euscaphis japonica (Thunb.) Kanitz, etc, class II species (17 taxa) were Pseudostellaria coreana (Nakai) Ohwi, Dryopteris expansa (C.Presl) Fraser-Jenkins et Jermy and Gymnocarpium dryopteris (L.) Newman, etc, class III species (32 taxa) were containing; Cirsium setidens (Dunn) Nakai, Parasenecio pseudotaimingasa (Nakai) B.U.Oh and Saussurea eriophylla Nakai, etc, class IV species (9 taxa) were Deutzia paniculata Nakai, Carex ligulata Nees and Thuja orientalis L., etc, and class V species (10 taxon) were Orobanche filicicola Nakai, Lycoris chinensis var. sinuolata K.H.Tae & S.T.Ko and Lycoris sanguinea var. koreana (Nakai) T.Koyama, etc. Endemic species of korea were identified 40 taxa such as Broussonetia kazinoki var. humilis Uyeki, Pseudostellaria coreana (Nakai) Ohwi and Silene seoulensis Nakai, etc. Plant species designated as Natural Monument were 2 species that Daphniphyllum macropodum forest(No. 91) and Torreya nucifera forest(No. 153) receive protection. The naturalized plants were identified 30 taxa; Fallopia dumetorum (L.) Holub, Persicaria orientalis (L.) Spach and Rumex crispus L., etc. Among them the ecosystem disturbance wild plants was not discovered.

Reexamination on Foreign Collectors' Sites and Exploration Routes in Korea (III) - with respect to T. Uchiyama - (외국인의 한반도 식물 채집행적과 지명 재고(III): Tomijiro Uchiyama)

  • Kim, Hui;Choi, Byoung-Hee;Chang, Chin-Sung;Chang, Kae-Sun
    • Korean Journal of Plant Taxonomy
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    • v.37 no.2
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    • pp.203-215
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    • 2007
  • Uchiyama, Tomijiro visited the Korean peninsula including Busan, Incheon, Nampo, Pyongyang, Seoul, Mt. Geumgang of Gangwon-do, and Jeju-do twice for his plant collections in 1900 and 1902, respectively. During his plant explorations, Uchiyama collected numerous specimens which were investigated and studied by T. Nakai (Flora Koreana I and II and other publications) and H. $L{\acute{e}}veill{\acute{e}}$ later. Unfortunately all collection sites were simply described by Nakai in Romanized characters, so that it is difficult to pinpoint those sites using the current or the old Korean map. From this study, many locality names were reviewed based on his own plant specimens at TI and literatures, and those were listed as the order of his collection dates. Based on specimens deposited at TI, only ca. 200 specimens were confirmed, although 1,674 specimens were listed by Nakai. Among his collections, 2/3 of his collections were conducted in 1902 and among them 41 specimens were cited as type collections by Nakai.

Thirteen Weeks Repeated Oral Dose Toxicity Study of Oplopanax elatus (Nakai) Nakai Hydrothermal Extract Powder in Sprague-Dawley Rats (Sprague-Dawley 랫드를 이용한 땃두릅나무 열수추출물 분말의 13주 반복 경구투여 독성에 관한 연구)

  • Yoo, Nam Ho;Kwon, Yongsoo;Chun, Hyeon Soo;An, Kyu Sup;Kim, Hye Jin;Ryu, Hyeon Yeol;Lee, So Min;Song, Kyung Seuk;Park, Byung Jun;Kim, Myong Jo
    • Korean Journal of Pharmacognosy
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    • v.50 no.4
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    • pp.260-271
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    • 2019
  • This study aimed to evaluate the safety of Oplopanax elatus (Nakai) Nakai hydrothermal extract powder. It was conducted using male and female Sprague-Dawley (SD) rats. The test group was established with dose of 500 (low-dosage group), 1,000 (medium- dosage group), and 2,000 (high- dosage group) mg/day. These are investigated that number of dead animals, general symptoms, weight changes, food consumption, ophthalmological examination, urinalysis, urine volume, hematological values, plasma coagulation time values, serum biochemical values, absolute organ weight, relative organ weight and histopathological finding during the experiment. As a result of the above, toxicological changes were not observed. Therefore, the non-toxic content of Oplopanax elatus (Nakai) Nakai hydrothermal extract powder is determined to be 2,000 mg/kg/day, and target organ was not observed.

Analysis of Asarone, Coumarin and Thujone in Medicinal Plants Used in Brewing a Korean Traditional Folk Wine (민속주 부재료로 이용되는 식물성 방향재료 및 약용재료중의 Asarone, Coumarin, Thujone의 분석)

  • Jo, Jung-Ok;Kim, Sun-Min;Kim, Kyong-Su
    • Applied Biological Chemistry
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    • v.42 no.3
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    • pp.210-217
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    • 1999
  • To detect the toxic relevant components, asarone, coumarin and thujone, in the 87 medicinal plants used in brewing a Korean traditional folk wine, their 20% ethanol extracts were prepared and purified by a SPE(solid phase extraction) method. The toxic components in the purified extracts were identified by GC-FID and GC/MS analysis. On analyses, asarone was detected in 6 species, Acorus gramineus Solander, Acorus asiaticus Nakai, Angelia gigus Nakai, Santalum album, etc.; coumarin in 22 species, Anethum graveolens, Foeniculum vulgare Gaertner, Lithosperum erythrorhizon Siebold et Zuccarinii, etc.; thujone in 24 species, Achyranthes japonica Nakai, Amomum xanthiodes Wallich, Artemisia asiatia Nakai, seed of Cannabis sativa L., Caragana sinica R., Chrysanthemum morifolium Ramat, Codonopsis lanceolata Bentham et flooker, Foeniculum vulgare Gaertner, etc.

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