• Title/Summary/Keyword: NPD-induced mutation

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Desmutagenic Effects of Extracts Aloe with Different Solvents (알로에 용매별 추출물의 항변이원성)

  • 오명철;오창경;안용석;고정림;오혁수;김수현
    • Korean journal of food and cookery science
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    • v.16 no.5
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    • pp.385-389
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    • 2000
  • Desmutagenic effects of water-soluble and water-insoluble fractions from Aloe vera and Aloe avoresence with different solvents against the mutagenicity of 4-nitro-o-phenylenediamine(NPD) were investigated. Desmutagenic effects of water-insoluble fractions from Aloe vera and Aloe avoresence against NPD-induced mutations in TA97 and TA98 strains were very high compared with water-soluble fractions: whereas water-soluble fractions from two kinds of Aloes showed the inhibition effects of 4∼56% water-insoluble fractions showed the activities of 54∼100% for Aloe vera and 74∼100% for Aloe avoresence. Especially, the addition of 20 $\mu$ι of water-insoluble fractions per plate showed high activities up to 90% in TA97 and TA98 strains.

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