• 한국염색가공학회:학술대회논문집
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• 한국염색가공학회 2009년도 학술발표대회
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• pp.45-46
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• 2009

In this study, 12 azo disperse dyes based on phthalimide were synthesized including their precursors. The chemical structures of the dyes and the corresponding precursors were analyzed by the GC-MASS, $^1H$ NMR spectra and elemental analysis. The dyeability on PET, such as step dyeing and build-up properties and color fastness were examined using conventional exhaust dyeing procedures.

• Bulletin of the Korean Chemical Society
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• 제31권12호
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• pp.3530-3538
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• 2010

In this study 1-[4-(2-methoxy benzyl)-6-aryl-pyridazin-3(2H)-ylidene] hydrazines were used for the synthesis of new heterocyclic systems such as thiazolidine, phthalazine, pyrazolo, tetrazolo, hydrazide and new pyridazine derivatives to explore the effect of silver nanoparticles on their biological activity efficiency. Structures of the new heterocycles were characterized by the aid of several analytical techniques including; $^1H$-NMR, FTIR and mass spectra. Silver nanoparticles were synthesized by a simple methodology and the formation of silver nanoparticles was confirmed by transmission electron microscopy (TEM) and UV studies. Most of the new prepared heterocycles were evaluated in vitro as new antimicrobial agents. Combination effects of the silver nanoparticles on the antimicrobial activity of the new heterocycles were investigated using the disk diffusion method. Compound 10a exhibited the strongest enhancing effect of silver nanoparticles solution against Aspergillus flavus and Candida albicans.

• 대한화학회지
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• 제25권1호
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• pp.38-43
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• 1981

L-Glutamic acid와 aniline 誘導體로부터 다음과 같은 새로운 pyrrolidone-anilide誘導體를 合成했다. 이 化合物들의 構造가 元素分析, UV, IR, NMR 그리고 Mass 스펙트럼으로 (R)-2-pyrrolidone-5-carbox-p-chloroanilide, (R)-2-pyrrolidone-5-carbox-o-toluidide, (R)-2-pyrrolidone-5-carbox-m-toluidide, (R)-2-pyrrolidone-5-carbox-p-toluidide임이 확인되었다. 이 化合物들의 무우, 벼 種子發芽와 生育에 대한 phytotoxicity을 調査한 結果는 다음과 같다. 이 化合物들은 벼 種子에 대하여 發芽 및 發根抑制?果를 나타내었다. 그 중에서 (R)-2-pyrrolidone-5-carboxanilide와 (R)-2-pyrrolidone-5-carbox-p-chloroanilide 誘導體는 무우 種子의 發芽와 生育을 현저하게 抑制하였다. 또한 (R)-2-pyrrolidone-5-carboxtoluidide 誘導體에 있어서 methyl group의 結合位置 (ortho, meta, para)에 따라서 무우의 生育抑制率이 다르다는 것을 알았다. 즉 (R)-2-pyrrolidone-5-carbox-m-toluidide는 (R)-2-pyrrolidone-5-carbox-o-toluidide와 (R)-2-pyrrolidone-5-carbox-p-toluidide 보다 무우 種子의 生育阻害現象이 현저하였다.

• 대한화학회지
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• 제57권6호
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• pp.731-737
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• 2013

A convenient synthesis of bifunctional sulfonamide-amide derivatives was reported. Amide coupling of 4-methyl benzoic acid 1 followed by reaction with chlorosulfonic acid produce ethyl-4-(3-(chlorosulfonyl)-4-methylbenzoyl)piperazine-1-carboxylate 4. The resulted compound on further treatment with various anilines produces the title sulfonamide-amide derivatives 5a-n. The configurations of these compounds were established by elemental analysis, IR, $^1H$ NMR, mass spectra, and by their preparation from the corresponding 4-methyl benzoic acid 1 and chlorosulfonic acid. All these new compounds demonstrate significant in vitro antibacterial and antifungal activities against all bacterial and fungal strains.

• 한국미생물·생명공학회지
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• 제10권3호
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• pp.211-215
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• 1982

Streptomyces griseorubiginosus var. soyoensis 에 의하여 두가지의 항진균성 항생물질이 생성되었는데 하나는 trans-cinnamamide 이었고 다른 하나는 UV, IR, NMR, mass spectrum 및 화학반응의 결과로 새로운 tetraene계 화합물임이 밝혀져 이 물질을 Tetraene KM-A라 하였다. 본 물질의 항균성을 조사한 결과 곰팡이 및 효모류에 대하여는 강한 항진균성을 나타내었으나 항세균성은 없었다. 배지에 sterol류를 첨가하였을때 Tetraene KM-A의 항균력이 없어지는 것으로 보아 stesoid와 결함함을 알수 있고 항균작용도 이와 관련이 있는 것으로 판단하였다. Tetraene KM-A의 mouse 및 rat에 대한 복강주사에 의한 $LD_{50}$ 은 각각 84.3과 90.4mg/kg이였으며 mouse에 대만 경구독성은 1503mg/kg이었다.

• 약학회지
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• 제30권2호
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• pp.73-78
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• 1986

Peucedanum terebinthaceum Fischer (Umbelliferae) known as "Gi Reum Na Mool" in Korea and used for the treatment of cough, phlegm, headache and common cold etc. The substances were isolated from the fruits of Peucedanum terebinthaceum and identified by UV, GLC, IR, NMR, Mass spectra and physico-chemical tests. The steroidal compounds from the fruits were identified as $\beta$-sitosterol (tR 33.01 min.) and stigmasterol (tR 28.87 min.) by GLC. Substance I (colorless prismatic crystal, $C_{19}H_{20}O_5$, mp $110~111^{\circ}$) was identified as decursin which is one of the pyranocoumarin. Hydrolysis of substance I with 5%-potassium hydroxide produced decursinol. Acetylation of decursinot gave its monoacetate, white needles, $C_{16}H_{16}O_5$. Substance II(light yellowish white needle crystal, $C_9H_6O_3$, mp $227~228^{\circ}$) was proved to be umbelliferone. Substance I, decursin, was isolated for the first time from the fruits of Peucedanum spp. (Umbelliferae).

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 1999년도 The 6th International Symposium on the Development of Anti-Cancer Resource from Plants
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• pp.110-117
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• 1999

A new lignan named as hibiscuside, (+) pinoresinol 4-O-[-glucopyranosyl (12) -rhamnoside] (1), and a known lignan, syringaresinol (2) were isolated from the root bark of Hibiscus syriacus together with two feruloyltyramines (3,4) and three known isoflavonoids (5,6,7). The structures of these compounds have been established on the basis of their NMR, Mass, UV spectra. Among these phenolic compounds,6-O-acetyl daidzin (5), 6-O- acetyl genistin (6), and 3-hydroxy daidzein (7) with IC50 values of 8.2, 10.6, and 4.1 M, respectively, significantly inhibited lipid peroxidation in rat liver microsomes Hibiscuside (1), E and Z-N-feruloyl tyramines (3,4) exhibited moderate antioxidant activity.

• Bulletin of the Korean Chemical Society
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• 제1권2호
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• pp.54-57
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• 1980

Trichloromethylphosphonyl dichloride was prepared by the aluminium chloride method. We synthesized several heterocyclic compounds containing phosphorus atom by the stepwise esterification of trichloromethylphosphonyl dichloride with ethylene glycol, 2-mercaptoethanol, ethylene diamine, and 2-aminoethanol and the resulting heterocyclic compounds are 2-trichloromethyl-1,3,2-dioxa-, 2-trichloromethyl-1,3,2-thioxa-, 2-trichloromethyl-1,3,2-diaza-, 2-trichloromethyl-1,3,2-diaza-, and 2-trichloromethyl-1,3,2-oxazaphospholane-2-oxide. The best results were obtained in the solution of triethylamine as hydrochloric acid trapping agent. The structure of five-membered heterocyclic phosphonates were characterized by their IR, NMR, and elementary analysis and the mass spectra of the compounds were analyzed.

• Bulletin of the Korean Chemical Society
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• 제18권3호
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• pp.311-316
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• 1997

The synthesis and characterization of the mononuclear group 13 heterocyclic carboxaldehyde methyldithiocarbazate complexes Me2M[NC5H4CRNNC(S)SCH3] (M=Al, R=H(1); M=Ga, R=H(2); M=Al, R=CH3(3); M-Ga, R=CH3(4); M=In, R=CH3(5)) are described. Compounds 1-5 were prepared by the reaction of MMe3 (M=Al, Ga, In) with 2-formy or 2-acetylpyridine-S-methyldithiocarbazate in toluene. These compounds 1-5 have been characterized by microanalysis, NMR (1H, 13C) spectroscopy, mass spectra, and single-crystal X-ray diffraction. X-ray single-crystal diffraction analyses reveal that 4-5 are mononuclear metal compounds with coordination number of 5 and N,N,S coordination mode.

• Natural Product Sciences
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• 제13권3호
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• pp.229-233
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• 2007

Chemical investigation of the crude extract of the Egyptian marine tunicate Eudistoma laysani led to the isolation of a new nucleoside; 3-deazainosine and four known ones; inosine, 2'-deoxyuridine, adenosine and 2'-deoxyadenosine. Structural elucidation of the isolated compounds was based on intensive studies of their spectral data including 1D ($^{1}H$ and $^{13}C$) and 2D ($^{1}H-^{1}H$ COSY, HMQC, HMBC) NMR together with mass spectra. The antioxidant effects of the isolated compounds were determined using DPPH, where they exhibited significant activities.