• Title/Summary/Keyword: NMR/MRI

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On-line Magnetic Resonance Quality Evaluation Sensor

  • Kim, Seong-Min;McCarthy, Michael J.;Chen, Pictiaw;Zion, Boaz
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 1996.06c
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    • pp.314-324
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    • 1996
  • A high speed NMR quality evaluation sensor was designed , constructed and tested . The device consists of an NMR spectrometer coupled to a conveyor system. The conveyor was run at speeds ranging from 0 to 250 mm/s. Spectral of avocado fruits and one-dimensional magnetic resonance images of pickled olives were acquired while the samples were moving on a conveyor belt mounted through a 20Tesla NMR magnet with a 20 mm diameter surface coil and a 150 mm diameter imaging coil respectively. Fro a magnetic resonance spectrum analysis, motion through variations in the magnetic field tends to narrow spectral line width just like using sample rotation in high resolution NMR to narrow spectral line width. Spectrum analysis was used to detect the dry weight of avocado fruits using the ratio oil and water resonance peaks. Good correlations maximum r=0.970@ 50 mm/s and minimum r=0.894@250mm/s ) between oil and water resonance peak ratio and dry weight of avocados were observed at speeds ra ging from0 to 250mm/s. For the application of magnetic resonance imaging (MRI) method, the projections were used to distinguish between pitted and non-pitted olives . Effect of fruit position in the coil was tested and coil degree effects were noticed when projects were generated under dynamic conditions. Various belt speeds (up to 250mm/s) were tested and detection results were compared to static measurements. Higher classification errors were occurred at dynamic conditions compared to errors while olives were at rest.

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A study on the effect of the condition number in the magnetic field mapping of the Air-Core solenoid

  • Huang, Li;Lee, Sangjin
    • Progress in Superconductivity and Cryogenics
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    • v.17 no.2
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    • pp.31-35
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    • 2015
  • Mapping is a useful tool in the magnetic field analysis and design. In some specific research area, such as the nuclear magnetic resonance (NMR) or the magnetic resonance imaging (MRI), it is important to map the magnetic field in the interesting space with high accuracy. In this paper, an indirect mapping method in the center volume of an air-core solenoid is presented, based on the solution of the Laplace's equation for the field. Through the mathematical analysis on the mapping calculation, we know that the condition number of the matrix, generated by the measurement points, can greatly affect the error of mapping result. Two different arrangement methods of the measurement points in field mapping are described in this paper: helical cylindrical line (HCL) method and parallel cylindrical line (PCL) method. According to the condition number, the HCL method is recommended to measure the field components using one probe. As a simple example, we mapped the magnetic fields in a MRI main magnet system. Comparing the results in the different methods, it is feasible and convenient to apply the condition number to reduce the error in the field mapping calculation. Finally, some guidelines were presented for the magnetic field mapping in the center volume of the air-core solenoid.

T2 Relaxographic Mapping using 8-echo CPMG MRI Pulse Sequence

  • E-K. Jeong;Lee, S-H.;J-S. Suh;Y-Y wak;S-A. Shin;Y-K. Kwon;Y. Huh
    • Journal of the Korean Magnetic Resonance Society
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    • v.1 no.1
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    • pp.7-20
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    • 1997
  • The mapping of the spin-spin relaxation time T2 in pixed-by-pixel was suggested as a quantitative diagnostic tool in medicine. Although the CPMG pulse sequence has been known to be the best pulse sequence for T2 measurement in physics NMR, the supplied pulse sequence by the manufacture of MRI system was able to obtain the maximum of 4 CPMG images. Eight or more images with different echo time TEs are required to construct a reliable T2 map, so that two or more acquisitions were required, which easily took more than 10 minutes. 4-echo CPMG imaging pulse sequence was modified to generate the maximum of 8 MR images with evenly spaced echo time TEs. In human MR imaging, since patients tend to move at least several pixels between the different acquisitions, 8-echo CPMG imaging sequence reduces the acquisition time and may remove any misregistration of each pixel's signal for the fitting T2. The resultant T2 maps using the theoretically simulated images and using the MR images of the human brain suggested that 8 echo CPMG sequence with short echo spacing such as 17∼20 msec can give the reliable T2 map.

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Pumping-up Current Characteristics of Linear Type Magnetic Flux Pump

  • Chung, Yoondo;Muta, Itsuya;Hoshino, Tsutomu;Nakamura, Taketsune;Ko, Taekuk
    • Progress in Superconductivity and Cryogenics
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    • v.6 no.2
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    • pp.29-34
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    • 2004
  • The linear type flux pump aims to compensate a little bit decremental persistent current of the HTS magnet in NMR and MRI spectrometers. The flux pump mainly consists of DC bias coil, 3-phase AC coil and Nb foil. The persistent current in closed superconductive circuit can be easily adjusted by the 3-phase AC current, its frequency and the DC bias current. In the experiment, it has been investigated that the flux pump can effectively charge the current in the load coil of 543 mH for various frequencies in 18 minutes under the DC bias of 10 A and the AC of 5 $A_{rms}$. The maximum magnitudes of pumping current and load magnet voltage are 0.72 A/min and 20 ㎷, respectively. Based on simulation results by the FEM are proved to nearly agree with experimental ones.

Determination of Correlation Times of New Paramagnetic Gadolinium MR Contrast Agents by EPR and 17O NMR

  • Kim, Hee-Kyung;Lee, Gang-Ho;Kim, Tae-Jeong;Chang, Yong-Min
    • Bulletin of the Korean Chemical Society
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    • v.30 no.4
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    • pp.849-852
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    • 2009
  • The work describes EPR and 17O NMR measurements followed by theoretical calculation of the rotational correlation time $({\tau}_R)$, the water residence time $({\tau}_m)$, and the longitudinal electronic spin relaxation time $(T_{le})$(T_1e) for two new gadolinium complexes 1 and 2 of the type [$Gd(L)(H_2O)$] (L = tranexamic esters) in order to investigate their efficiency as a paramagnetic contrast agent (PCA). Of three correlation times, τR plays a major and predominant role to the unusually high relaxivity of 1 and 2 as compared with that of clinically approved MR CAs such as [$Gd(DTPA)(H_2O)]2‐ (Magnevist${\circledR}$), [Gd(DTPA-BMA)(H2O)] (Omniscan${\circledR}$), and $[Gd(DOTA)(H_2O)]^-$ (Dotarem${\circledR}$). The presence of bulky tranexamic ester in the ligand seems to be responsible for the conformational rigidity, which in turn causes such great an increase in ${\tau}_R$.

Combined MRI and Relaxogram: A New Method of Fat Study (MRI와 Relaxogram을 이용한 지질 연구의 새로운 기법에 관한 연구)

  • Yongmin Chang;Yoo, Done-Sik;Kim, Tae-Hun;Kim, Yong-Joo;Kang, Duk-Sik;Robert B. Clarkson
    • Progress in Medical Physics
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    • v.10 no.1
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    • pp.23-32
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    • 1999
  • Combined MRI and Relaxogram approach was introduced as a very useful tool for fat study. The phantoms simulating homogeneous mixture of fat and non-fat environments were measured with spin echo pulse sequence on a 0.15 T whole body imager. From 45 scans, the Tl values were obtained by fitting the data to continuous distribution (CONTIN) of relaxation time. This relaxogram gives broad distributions of relaxation time, which are characterized by a number of peaks with characteristic T1 values. Two distinct peaks in relaxogram were observed and identified as signals from com oil and gelatin gel. This model system can be served as simulating the distribution of fat in muscle. Also the relative ratio of two components, which is proportional to the area under the peak, is estimated and compared to nominal values. Based on the good agreement between two predictions, the values from our proposed method agreed with nominal values within $\pm$7 % error. The effects of different concentration of contrast agent and different region of interest are presented. To optimize total scan times, the minimum required data points and so further reduction in total scan times are discussed.

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수삼 내부의 자기공명영상 특성

  • 손재룡;이강진;최동수;김기영;강석원;최규홍
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2003.10a
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    • pp.151-152
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    • 2003
  • 최근 NMR, MRI, x-선 등 전자파의 기술이 발전되면서 이들을 이용하여 내부품질을 검출하는 보다진보된 연구가 수행되고 있다. 관련 연구로는 자기공명영상을 이용하여 내공수삼 및 정상수삼의 내부를 촬영하여 T$_1$, T$_2$의 값을 측정하여 내부조직의 이상유무를 추정하였고, 또한 MRI에 의해 수삼의 내부품질 뿐만 아니라 연근 판정 가능성을 검토하는 등 많은 연구가 수행되고있다. 이 연구에서는 MRI 시스템을 이용하여 수삼의 내부단면 영상을 획득하여 내부결함 유무를 검출하고, 또한 동일한 수삼을 대상으로 홍삼 제조 후 내부품질의 변화 특성을 조사하고자 수행하였다. 공시재료는 충북 음성에 있는 인삼연초연구원에서 4~6년 근 된 수삼을 이용하였고, 시험 장비로는 국내 MRI 생산 전문 업체인 ISOL Tech. Co.에서 개발한 의료용 장비인 CHORUS 1.5T(자속밀도 1.5 Tesla)를 이용하였다. 슬라이스 두께/간격은 5mn/5mn, 촬영 단면수는 15장/시료, 영상영역(FOV)은 180mmx90mm, image size는 256$\times$128 pixels 그리고 TR/TE는 각각의 이완상수별로 500/13(Tl), 4,000/63(T2) 및 2,200/21(Pd)에 대한 단면영상을 얻었다. 5개의 수삼을 동시에 뇌두에서 뿌리 쪽으로 MR 단면영상을 획득하였다. 이완상수 T$_1$, T$_2$, Pd에 대해서 MR 영상을 획득하였으며, 총 15장의 단면 영상 중 내부 상태를 가장 잘 식별 할 수 있는 영상을 조사한 결과 T$_1$과 Pd에서 촬영한 영상에서는 내부상태가 잘 나타났으나, T$_2$에서 얻은 영상은 영상의 손실이 많이 발생되었다. 한편, T$_1$에 대해서 뇌두에서 뿌리쪽으로 가면서 각 위치에 따라 수삼 내부의 부패된 영상이 나타나 이에 대한 판정은 가능한 것으로 나타났다. 2000년도와 2001년도에 각각 수확.저장된 수삼을 부위별로 단면영상을 MRI로 측정하고, 그 시료를 인삼연초연구원(음성시험장)에서 홍삼으로 제조한 후 수삼 상태에서의 내부품질과 홍삼으로 제조된 후의 내부품질 변화를 조사하였다. 총 20본의 수삼을 MRI 시스템으로 영상을 획득하였고, 모든 시료에 대해서 내부조직의 상태를 관찰하였다. 수삼의 수분함량은 뇌두로부터 1cm부위를 절단하여 조사하였고, 수삼조직은 절단시 단면의 달관 조사에 의한 성적이며 홍삼품질은 제조삼의 조직상태를 절단하여 육안판별로 검사하였다. 총 20본의 수삼 중 정상은 16본 이었고, 이들은 홍삼으로 제조된 후 내공 내백 등이 혼재되어 나타났으며 정상수삼이 정상홍삼으로 나타난 경우는 5본이었고, 내백은 5본, 내공은 6본으로 조사되었다. 또한 수삼에서 4본은 썩은 부위가 포함되어있는 수삼이었는데 홍삼으로 제조되었을 때 3본은 내백으로 되었고 1 본은 수삼에서 썩은 부위가 1/4정도로 미미해서 홍삼 제조시 정상으로 나타났다. 일반적으로 홍삼 제조시 내공의 발생은 제조공정에서 나타나는 경우가 많으며, 내백의 경우는 홍삼으로 가공되면서 발생하는 경우가 있고, 인삼이 성장될 때 부분적인 영양상태의 불충분이나 기후 등에 따른 영향을 받을 수 있기 때문에 앞으로 이에 대한 많은 연구가 이루어져야할 것으로 판단된다.

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The Study on the Superconducting MRI Magnet of 68 cm in Room Temperature Bore (68 cm 상온 보아를 갖는 MRI용 초전도마그네트에 관한 연구)

  • Jin, H.B.;Oh, B.H.;Cho, J.W.;Oh, S.S.;Kwon, Y.K.;Ha, D.W.;Lee, E.Y.;Kim, H.J.;Kim, O.K.;Choi, B.J.;Ryu, K.S.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.11
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    • pp.142-146
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    • 1996
  • In this paper, we present the main research results on the 2 Tesla class - superconducting MRI magnet which we have developed. Multi section type superconducting MRI main coil and various superconducting shims were designed and fabricated for obtaining the high field homogeneity, which is requested in the MR imaging. After assembling the magnet with room temperature bore cryostat field homogenity has been measured and analyzed by NMR field mapping system. According to this, field homogeneity of 22 ppm / 30 cm dsv was confirmed.

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Fabrication and Test of Persistent Current Switch for HTS Magnet System

  • Hyoungku Kang;Kim, Jung-Ho;Jinho Joo;Yoon, Yong-Soo;Ko, Tae-Kuk
    • Progress in Superconductivity and Cryogenics
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    • v.5 no.1
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    • pp.92-96
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    • 2003
  • This paper deals with the characteristics of persistent current switch (rCS) system fer applied HTS magnet system. To apply the high-Tc superconductor in superconducting machine such as motror, generator, MAGLEV, MRI, and NMR, the study on high-Tc superconducting persistent current mode must be performed. In this experiment, the PCS system consists otd superconducting magnet, PCS and magnet power supply. The superconducting magnet was fabricated by connecting four double pancake coils (DPCs) in series. The PCS was inductive double pancake coil type and heated up by the SUS 303L tape heater. The optimal length of PCS was calculated and thermal quench state of PCS was simulated by using finite element method(FEM) and compared with experimental results. The optimal energy to normalize the PCS was calculated and introduced. Finally, the persistent current was observed with respect to various ramping up rate and magnitude of charging current.

Design of 5T HTS Magnet using 2G Wire (2G 선재를 이용한 5T급 고온초전도 마그넷 설계)

  • Ku, Myung-Hwan;Kim, Dong-Lak;Choi, Yeon-Suk;Lee, Woo-Ho;Shin, Dong-Won;Kim, Myung-Su;Cha, Guee-Soo
    • Proceedings of the KIEE Conference
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    • 2011.07a
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    • pp.1117-1118
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    • 2011
  • NMR이나 MRI와 같은 고자장을 필요로 하는 마그넷은 높은 운전전류를 갖는 초전도 선재를 이용하여 제작된다. 이때 마그넷은 여러 코일을 겹쳐서 제작하는 것이 일반적이고, 크게 내측마그넷과 외측 마그넷으로 구분할 수 있다. 본 논문에서는 15T 외측마그넷 안에서 동작하는 5T급 내측마그넷의 설계 과정을 나타내었다. 내측마그넷은 2세대 고온초전도 선재를 이용하여 설계되고, 4.2K의 액체헬륨 안에서 동작한다. 마그넷의 임계전류는 초전도 선재의 $I_c$-B 특성을 고려하여 산정하였고, 임계전류를 바탕으로 운전전류를 결정하였다. 내측마그넷의 발생자장이 5T를 만족하는 운전전류와 마그넷의 형상을 계산을 통하여 제시하였다.

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