• Title/Summary/Keyword: NIRS

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Cerebral Oxygenation during Apnea in Preterm Infants: Effects of Accompanying Peripheral Oxygen Desaturation

  • Choi, Seo Hee;Lee, Juyoung;Nam, Soo Kyung;Jun, Yong Hoon
    • Neonatal Medicine
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    • v.28 no.1
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    • pp.14-21
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    • 2021
  • Purpose: Premature infants have immature respiratory control and cerebral autoregulation. We aimed to investigate changes in cerebral oxygenation during apnea with and without peripheral oxygen desaturation in premature infants. Methods: This prospective observational study was conducted at Inha University Hospital. Near-infrared spectroscopy (NIRS)-monitored regional cerebral oxygen saturation (rScO2) and pulse oximeter-monitored peripheral oxygen saturation (SpO2) were assessed during the first week of life in 16 stable, spontaneously breathing preterm infants. Apneic episodes that lasted for ≥20 seconds or were accompanied by desaturation or bradycardia were included for analysis. The average rScO2 value during the 5-minute prior to apnea (baseline), the lowest rScO2 value following apnea (nadir), the time to recover to baseline (recovery time), the area under the curve (AUC), and the overshoot above the baseline after recovery were analyzed. Results: The median gestational age and birth weight of the infants were 29.2 weeks (interquartile range [IQR], 28.5 to 30.5) and 1,130 g (IQR, 985 to 1,245), respectively. A total of 73 apneic episodes were recorded at a median postnatal age of 2 days (IQR, 1 to 4). The rScO2 decreased significantly following apneic episodes regardless accompanied desaturation. There were no differences in baseline, nadir, or overshoot rScO2 between the two groups. However, the rScO2 AUC for apnea with desaturation was significantly higher than that for apnea without desaturation. Conclusion: Cerebral oxygenation can significantly decrease during apnea, especially when accompanied by reduced SpO2. These results add the evidence for the clinical utility of NIRS in monitoring premature infants.

Secondary Neutron Dose in Carbon-ion Radiotherapy: Investigations in QST-NIRS

  • Yonai, Shunsuke;Matsumoto, Shinnosuke
    • Journal of Radiation Protection and Research
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    • v.46 no.2
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    • pp.39-47
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    • 2021
  • Background: The National Institutes for Quantum and Radiological Science and Technology-National Institute of Radiological Sciences (QST-NIRS) has continuously investigated the undesired radiation exposure in ion beam radiotherapy mainly in carbon-ion radiotherapy (CIRT). This review introduces our investigations on the secondary neutron dose in CIRT with the broad and scanning beam methods. Materials and Methods: The neutron ambient dose equivalents in CIRT are evaluated based on rem meter (WENDI-II) measurements. The out-of-field organ doses assuming prostate cancer and pediatric brain tumor treatments are also evaluated through the Monte Carlo simulation. This evaluation of the out-of-field dose includes contributions from secondary neutrons and secondary charged particles. Results and Discussion: The measurements of the neutron ambient dose equivalents at a 90#x00B0; angle to the beam axis in CIRT with the broad beam method show that the neutron dose per treatment dose in CIRT is lower than that in proton radiotherapy (PRT). For the scanning beam with the energy scanning technique, the neutron dose per treatment dose in CIRT is lower than that in PRT. Moreover, the out-of-field organ doses in CIRT decreased with distance to the target and are less than the lower bound in intensity-modulated radiotherapy (IMRT) shown in AAPM TG-158 (American Association of Physicists in Medicine Task Group). Conclusion: The evaluation of the out-of-field doses is important from the viewpoint of secondary cancer risk after radiotherapy. Secondary neutrons are the major source in CIRT, especially in the distant area from the target volume. However, the dose level in CIRT is similar or lower than that in PRT and IMRT, even if the contributions from all radiation species are included in the evaluation.

The Analysis of Therapeutic Effects of Forest landscapes with different Water-scape types Using Hemodynamic measurement in Prefrontal cortex (전두엽 혈류 측정을 통한 산림녹지 내 수경관 유형별 치유 효과 분석)

  • Minji Kang;ChoHye Youn;Jeongwon Lee;Juyoung Lee
    • Journal of Environmental Science International
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    • v.33 no.1
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    • pp.1-8
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    • 2024
  • When situated in green landscapes, water bodies play a crucial role in positively influencing mood and mental health, yet research on the cognitive mechanisms underlying these therapeutic effects is lacking. This study is intended to examine differences in brain function among adult males exposed to forest landscapes with or without water bodies. The wooded landscapes included views of a waterfall, a valley, and a forest without water. The control group was exposed to a local urban landscape. Twelve adult males participated in a field experiment in which prefrontal cortex (PFC) activity was measured using near-infrared spectroscopy (NIRS). In the experiment, participants engaged in low-intensity walking in three forested areas with similar vegetation and climatic conditions. Participants showed significant differences in left PFC activity depending on whether they were in the three forested landscapes or in the control landscape (P < 0.01). An analysis of variance (ANOVA) confirmed that significantly lower left PFC activity was recorded in the wooded landscape containing a water view . Notably, the lowest PFC values recorded in the landscape with a waterfall view suggest that landscapes with dynamic water flow may be associated with greater therapeutic benefits in terms of PFC activity than static landscapes. Our results underscore that water is a critical aspect of a landscape due to its therapeutic benefits and should be incorporated in the planning and design of green spaces for health promotion.

A Case Study on the Effectiveness of tDCS to Reduce Cyber-Sickness in Subjects with Dizziness

  • Chang Ju Kim;Yoon Tae Hwang;Yu Min Ko;Seong Ho Yun;Sang Seok Yeo
    • The Journal of Korean Physical Therapy
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    • v.36 no.1
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    • pp.39-44
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    • 2024
  • Purpose: Cybersickness is a type of motion sickness induced by virtual reality (VR) or augmented reality (AR) environments that presents symptoms including nausea, dizziness, and headaches. This study aimed to investigate how cathodal transcranial direct current stimulation (tDCS) alleviates motion sickness symptoms and modulates brain activity in individuals experiencing cybersickness after exposure to a VR environment. Methods: This study was performed on two groups of healthy adults with cybersickness symptoms. Subjects were randomly assigned to receive either cathodal tDCS intervention or sham tDCS intervention. Brain activity during VR stimulation was measured by 38-channel functional near-infrared spectroscopy (fNIRS). tDCS was administered to the right temporoparietal junction (TPJ) for 20 minutes at an intensity of 2mA, and the severity of cybersickness was assessed pre- and post-intervention using a simulator sickness questionnaire (SSQ). Result: Following the experiment, cybersickness symptoms in subjects who received cathodal tDCS intervention were reduced based on SSQ scores, whereas those who received sham tDCS showed no significant change. fNIRS analysis revealed that tDCS significantly diminished cortical activity in subjects with high activity in temporal and parietal lobes, whereas high cortical activity was maintained in these regions after intervention in subjects who received sham tDCS. Conclusion: These findings suggest that cathodal tDCS applied to the right TPJ region in young adults experiencing cybersickness effectively reduces motion sickness induced by VR environments.

Basic Study on the Development of Analytical Instrument for Liquid Pig Manure Component Using Near Infra-Red Spectroscopy (근적외선 분광법을 이용한 돈분뇨 액비 성분분석기 개발을 위한 기초 연구)

  • Choi, D.Y.;Kwag, J.H.;Park, C.H.;Jeong, K.H.;Kim, J.H.;Song, J.I.;Yoo, Y.H.;Chung, M.S.;Yang, C.B.
    • Journal of Animal Environmental Science
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    • v.13 no.2
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    • pp.113-120
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    • 2007
  • This study was conducted to measure Nitrogen(N), Phosphate($P_2O_5$), Potassium ($K_2O$), Organic matter(OM) and Moisture content of liquid pig manure by Near Infrared Spectroscopy(NIRS) and to develop an alternative and analytical instrument which are used for measurement of N, $P_2O_5$, $K_2O$, OM, and Moisture contents for liquid pig manure. The liquid pig manure sample's transmittance spectra were measured with a NIRS in the wavelength range of 400 to 2,500 nm. Multiple linear regression and partial least square regression were used for calibrations. The correlation coefficient(RSQ) and standard error of calibration(SEC) obtained for nitrogen were 0.9190 and 2.1649, respectively. The RSQ for phosphate, potassium, organic matter and moisture contents were 0.9749, 0.5046, 0.9883 and 0.9777, and the SEC were 0.5019, 1.9252, 0.1180 and 0.0789, respectively. These results are indications of the rapid determination of components of liquid pig manure through the NIR analysis. The simple analytical instrument for liquid pig manure consisted of a tungsten halogen lamp for light source, a sample holder, a quartz cell, a SM 301 spectrometer for spectrum analyzer, a power supply, an electronics, a computer and a software. Results showed that the simple analytical instrument that was developed can approximately predict the phosphate, organic matter and moisture content of the liquid pig manure when compared to the analysis taken by NIRS. The low predictability value of potassium however, needs further investigation. Generally, the experiment proved that the simple analytical instrument was reliable, feasible and practical for analyzing liquid pig manure.

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Fast Systemic Evaluation of Amylose and Protein Contents in Collected Rice Landraces Germplasm Using Near-Infrared Reflectance Spectroscopy (NIRS) (근적외선 분광분석기를 이용한 국내외 재래종 벼 유전자원의 아밀로스 및 단백질에 관한 대량 평가 체계구축)

  • Oh, Sejong;Lee, Myung Chul;Choi, Yu Mi;Lee, Sukyeung;Rauf, Muhammad;Chae, Byungsoo;Hyun, Do Yoon
    • Korean Journal of Plant Resources
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    • v.30 no.4
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    • pp.450-465
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    • 2017
  • This study was conducted to characterize the amylose and protein contents of 4,948 rice landrace germplasm using the NIRS model developed in the previous study. The average amylose content of the germplasm was 20.39% and ranged between 3.97 and 37.13%. The amylose contents in the standard rice were 4.99, 18.63 and 20.55% in Sinseonchal, Chucheong and Goami, respectively. The average protein content was 8.17% and ranged from 5.20 to 17.45%. Protein contents in Sinseonchal, Chucheong and Goami were 6.824, 6.869 and 7.839%, respectively. A total of 62% germplasm were distributed between 20.06% and 27.02% in amylose content. Germplasm of 81.60% represented protein content of 6.78-9.75%. The distinguishable ranges of amylose contents according to origin were 16.58-20.06% in Korea, 20.06-23.25% in Japan, 23.25-27.02% in North Korea, and 27.02-37.13% in China. In the protein content, approximately 30% of Chinese resources ranged from 9.75 to 17.45%, whereas less than 10% were detected in other origin accessions. Fifty resources were selected with low and high amylose ranging from 3.97-6.66% and 30.41-37.13%, respectively. Similarly, fifty resources were selected with low and high protein ranging from 5.20-6.09% and 13.21-17.45%, respectively. Landraces with higher protein could be adapted to practical utilization of food sources.

Statistical Analysis of Amylose and Protein Content in Landrace Rice Germplasm Collected from East Asian Countries Based on Near-Infrared Reflectance Spectroscopy (NIRS) (근적외선분광분석에 의한 동아시아 지역 재래종 벼 유전자원의 아밀로스 및 단백질 함량 변이분석)

  • Oh, Sejong;Choi, Yu Mi;Yoon, Hyemyeong;Lee, Sukyeung;Yoo, Eunae;Lee, Myung Chul;Rauf, Muhammad;Chae, Byungsoo
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.64 no.2
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    • pp.70-88
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    • 2019
  • A statistical analysis of 4,380 non-glutinous landrace rice germplasm collected from four East Asian countries namely South Korea (1,032), North Korea (994), Japan (800), and China (528) was conducted using normal distribution, variability index value (VIV), analysis of variation (ANOVA), and Duncan's multiple range test (DMRT) based on a data obtained from Near-Infrared Reflectance Spectroscopy (NIRS) analysis. In normal distribution, the average protein content was 8.2%, and the non-glutinous rice amylose, ranging over 10%, was found to be 22.0%. Protein content in most gremplasm was between 5.4 and 10.9%, and amylose content was between 15.0 and 28.9%. The VIV was 0.50 for protein, and 0.81 for non-glutinous rice amylose content. The average amylose content was 23.34% in Chinese, 21.55% in South Korean, 21.45% in Japanese, and 20.48% in North Korean resources, while the average protein content was found to be 9.02% in Chinese, 8.06% in Japanese, 8.04% in North Korean, and 7.99% in South Korean resources. ANOVA of amylose and protein content showed significant differences at p=0.01. The F-test value for amylose content was 94.92, and for protein content was 81.82 compared to the critical value of 3.79. DMRT of amylose and protein content revealed significant differences (p<0.01). Among the various germplasm obtained from different countries, that from North Korean had the lowest level of amylose content, whereas that from South Korea had the lowest level of protein content than all other resources. Chinese resources had the highest level of amylose and protein content. It is recommended to use these results in breeding fields.

The Output Characteristics of Transcranial Magnetic Stimulation with Voltage Variable Capacitor-Charging System

  • Kim, Whi-Young
    • Journal of information and communication convergence engineering
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    • v.8 no.2
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    • pp.205-211
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    • 2010
  • In this study, a Magnetic stimulation Pulse Train control technique is introduced and applied to Flyback converter operating in discontinuous conduction mode. In contrast to the conventional pulse width modulation control scheme, the principal idea of a Magnetic stimulation Pulse Train is to achieve output voltage regulation using high and low power pulses. The proposed technique is applicable to any converter operating in discontinuous conduction. However, this work mainly focuses on Flyback topology. In this paper, the main mathematical concept of the new control algorithm is introduced and simulations as well as experimental results are presented.

Discrimination of Alismatis Rhizoma According to Geographical Origins using Near Infrared Spectroscopy (근적외선분광법을 이용한 택사의 산지 판별법 연구)

  • Lee, Dong Young;Kim, Seung Hyun;Kim, Hyo Jin;Sung, Sang Hyun
    • Korean Journal of Pharmacognosy
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    • v.44 no.4
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    • pp.344-349
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    • 2013
  • Near infrared spectroscopy (NIRS) combined with multivariate analysis was used to discriminate the geographical origin of Alisma orientale from Korea (n=94) and China (n=72). Two-thirds of samples were selected randomly for the training set, and one-third of samples for the test set. Second derivative was used for the pretreatment of NIR spectra. Partial least square discriminant analysis (PLS-DA) models correctly discriminated 100% of the Korean and Chinese A. orientale samples. These results demonstrate the potential use of NIR spectroscopy combined with multivariate analysis as a rapid and accurate method to discriminate A. orientale according to their geographical origin.

Performance Comparison of Data Mining Approaches for Prediction Models of Near Infrared Spectroscopy Data (근적외선 분광 데이터 예측 모형을 위한 데이터 마이닝 기법의 성능비교)

  • Baek, Seung Hyun
    • Journal of the Korea Safety Management & Science
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    • v.15 no.4
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    • pp.311-315
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    • 2013
  • 본 논문에서는 주성분 회귀법과 부분최소자승 회귀법을 비교하여 보여준다. 이 비교의 목적은 선형형태를 보유한 근적외선 분광 데이터의 분석에 사용할 수 있는 적합한 예측 방법을 찾기 위해서이다. 두 가지 데이터 마이닝 방법론인 주성분 회귀법과 부분최소자승 회귀법이 비교되어 질 것이다. 본 논문에서는 부분최소자승 회귀법은 주성분 회귀법과 비교했을 때 약간 나은 예측능력을 가진 결과를 보여준다. 주성분 회귀법에서 50개의 주성분이 모델을 생성하기 위해서 사용지만 부분최소자승 회귀법에서는 12개의 잠재요소가 사용되었다. 평균제곱오차가 예측능력을 측정하는 도구로 사용되었다. 본 논문의 근적외선 분광데이터 분석에 따르면 부분최소자승회귀법이 선형경향을 가진 데이터의 예측에 가장 적합한 모델로 판명되었다.