• Title/Summary/Keyword: NIP

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Purification and Identification of Inhibitory Compounds from Cheongmoknosang Mulberry Leaves (Morus alba. L.) on Helicobacter pylori (청목노상 뽕잎으로부터 Helicobacter pylori 억제물질의 정제 및 동정)

  • Cho, Young-Je;Lee, Kyung-Hwan;Cha, Woen-Seup;Ju, In-Sik;Yun, Dong-Hyuck;An, Bong-Jeun;Lee, Seon-Ho;Kim, Myung-Uk;Kim, Jeung-Hoan;Chun, Sung-Sook
    • Journal of Applied Biological Chemistry
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    • v.52 no.2
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    • pp.65-69
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    • 2009
  • In this study, we tried to find the subject to inhibit H. pylori from Cheongmoknosang mulberry leaves extracts and to purify and identify them. Total phenolic compounds of hot water and 80% ethanol extracts are 17.6 and 16.1 mg/g. The activity of H. pylori inhibition at 80% ethanol extracts was determined as 15mm clear zone. The purification of inhibitory compounds were carried on $C_{18}$ column and MCI-gel CHP-20 column chromatography which were used a gradient procedure as increasing ethanol in $H_2O$. The chemical structure of purified inhibitory compounds on H. pylori were identified chlorogenic acid, caffeic acid, and rosmarinic acid by FAB-MS, $^1H-NMR$, $^{13}C-NMR$ and IR spectrum.

A Delphi Study on National Public Vaccine Research and Development Policy in Korea (델파이기법을 활용한 국가 공공(公共)백신 연구개발 정책수립 기초조사)

  • Lee, Somin;Yeo, Sang-Gu;Kang, Shin Jung;Han, Soon Young;Lee, Sang-Won
    • Health Policy and Management
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    • v.25 no.2
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    • pp.140-148
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    • 2015
  • Vaccination is the most powerful and useful preparation against infectious diseases. However, developing vaccines costs a lot and requires extensive long-term efforts. Therefore, the government should research and develop vaccines with a national-level policy. To greatly enhance the success rate of vaccine development, the policy should be set up considering priorities such as the current status of domestic research, the importance for public health, the urgency of research. The Delphi technique was utilized to draft this survey, through a brainstorming stage, then two inquiries, and finally the final panel meeting where unresolved items were discussed, to draw the conclusion. Among the results, firstly, the highest ranked item on centralized fields for vaccine development by the Ministry of Health was 'self-sufficiency of vaccines.' Secondly, 'emerging infectious disease' was most highly ranked in prioritized fields of vaccine development and research. Thirdly, for the vaccine that needs to be improved and developed further by the government to improve its efficacy and safety, BCG (Bacille de Calmette) for tuberculosis was ranked the highest on both types (intradermal and subcutaneous injection) from National Immunization Programme (NIP) and non-NIP. As for the high risk pathogens, 'anthrax' and 'smallpox' were first and second, consecutively. Lastly, 'development and control of vaccine candidates' was ranked the highest for the area in need for technique development in order to improve domestic vaccine's research level. The results of this study will be put to good use as basic data for the national vaccine research and development (R&D) policy of the country. This study was first step and more studies should be carried out for the final decision of the national vaccine R&D priority.

Effective Disaster Risk Management Measures Fall (추락재해의 효과적인 위험관리 방안)

  • Kim, Eun-Jeung;Ahn, Hong-Seob
    • Journal of the Korean Society of Safety
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    • v.27 no.2
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    • pp.42-48
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    • 2012
  • The present study was motivated by the needs to make diversified scientific approaches toward influential factors like human, technical, organization, policy and environmental on the basis of the specialized information concerning the cause for industrial accidents in a measure to prevent the falling accident which has the biggest priority among the three major frequent industrial accidents. In this connection, diverse policies have been practiced in the meantime, with little effects in fact to reduce occurrence of industrial accidents, seemingly because such policies have been practiced on the direct dimension, instead of tries to nip in the bud of fundamental causes. This study was thus conducted with a view to determine the causes that have influence on falling accidents from the overall context and unearth the factors requiring management with priority. For this aim, "Fall from Height"(2003), a study by HSE, UK was applied to various conditions of korea as an experiment to search for fundamental causes for falling accidents. The major findings of this study might be summed up as exploring a main critical path that has influence upon falling accidents and suggesting effective ways to cut down through the critical path.

Microcrystalline Silicon Thin Films and Solar Cells by Hot-Wire CVD (Hot-Wire CVD법에 의한 미세결정 실리콘 박막 증착 및 태양전지 응용)

  • Lee, Jeong-Chul;Yoo, Jin-Su;Kang, Ki-Hwan;Kim, Seok-Ki;Yoon, Kyung-Hoon;Song, Jin-Soo;Park, I-Jun
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2002.05b
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    • pp.66-69
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    • 2002
  • This paper presents deposition and characterizations of microcrystalline silicon$({\mu}c-Si:H)$ films prepared by hot wire chemical vapor deposition at substrate temperature below $300^{\circ}C$. The $SiH_{4}$ concentration$[F(SiH_{4})/F(SiH_{4})+F(H_{2})]$ is critical parameter for the formation of Si films with microcrystalline phase. At 6% of silane concentration, deposited intrinsic ${\mu}c-Si:H$ films shows sufficiently low dark conductivity and high photo sensitivity for solar cell applications. P-type ${\mu}c-Si:H$ films deposited by Hot-Wire CVD also shows good electrical properties by varying the rate of $B_{2}H_{6}$ to $SiH_{4}$ gas. The solar cells with structure of Al/nip ${\mu}c-Si:H$/TCO/glass was fabricated with single chamber Hot-Wire CVD. About 3% solar efficiency was obtained and applicability of HWCVD for thin film solar cells was proven in this research.

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Effect of Calendering Variables on the Properties of Coated paper (캘린더 처리조건이 도공지 품질에 미치는 영향)

  • 이용규;김창근;이광섭
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.33 no.2
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    • pp.49-57
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    • 2001
  • This study was performed to identify the effect of calendering variables on the properties of coated paper such as sheet gloss, surface roughness, opacity, etc. The effect of calendering variables including the number of nips, pressure, machine speed and moisture content on the properties of coated paper was investigated. The calender was installed with two steel rolls and one cotton-made roll. With this calender, the coated sheets were passed through the calender from 1 to 4 times, applying the linear pressure on calender rolls, 5 through 100kg/cm and operating the machine speed 3 to 12m/min. Also, the moisture content of coated sheet was varied about 5 and 10%. It was found that sheet gloss and surface roughness of coated paper was increased with increasing the number of passing nips, linear roll pressure and the moisture content of coated paper. But it was shown that the opacity and brightness of coated paper were decreased under the above conditions due to the blackening. It was also suggested that the soft nip possibly increased the thermoplasticity of coating layer with the heat of steel roll, resulting in the reinforcement of surface properties positively. The sheet gloss and surface roughness of coated paper could be improved by the longer dwell time over the rolls.

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Electrical and Structural Properties of Microcrystalline Silicon Thin Films by Hot-Wire CVD (Hot-Wire CVD법에 의한 microcrystalline silicon 박막의 저온 증착 및 전기 구조적 특성)

  • 이정철;유진수;강기환;김석기;윤경훈;송진수;박이준
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2002.07a
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    • pp.387-390
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    • 2002
  • This paper presents deposition and characterizations of microcrystalline silicon(${\mu}$c-Si:H) films prepared by hot wire chemical vapor deposition at substrate temperature below 300$^{\circ}C$. The SiH$_4$ concentration[F(SiH$_4$)/F(SiH$_4$).+(H$_2$)] is critical parameter for the formation of Si films with microcrystalline phase. At 6% of silane concentration, deposited intrinsic ${\mu}$c-Si:H films shows sufficiently low dark conductivity and high photo sensitivity for solar cell applications. P-type ${\mu}$c-S:H films deposited by Hot-Wire CVD also shows good electrical properties by varying the rate of B$_2$H$\_$6/ to SiH$_4$ gas. The solar cells with structure of Al/nip ${\mu}$c-Si:H/TCO/g1ass was fabricated with single chamber Hot-Wire CVD. About 3% solar efficiency was obtained and applicability of HWCVD for thin film solar cells was proven in this research.

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Comparison of Water Quality According to Seasonal Variation in Mokpo and Wando Costal Areas

  • Kim, Woo-Hang;Lee, Young-Sik
    • Journal of Environmental Science International
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    • v.17 no.3
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    • pp.269-273
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    • 2008
  • The objective of this study was to evaluate the relationship between nutrients and phytoplankton. This study was done by the comparison to two costal areas Mokpo, which inflow fresh water, and Wando. In August, salinity of the sea water decreased by 3.5-4.5%o in Mokpo coastal area, but was not nearly decreased in Wando coastal area. This suggests a lot of fresh water inflow in Mokpo coastal area. DIN and DIP were decreased by water temperature increasing in Wando. However, in Mokpo, DIN and DIP were increased greatly during the summer season. Nitrogen was limited to a 10 NIP ratio especially during the summer season in Wando coastal area while phosphorus in Mokpo coastal area was limited with over 28 N/P ratio in all the seasons. Coefficient of determination$(r^2)$ between DIP and Chl.-a was 0.91 in Mokpo coastal area. On the other hand, Coefficient of determination$(r^2)$ between Chl.-a and DIN, DIP were 0.93 and 0.89, respectively, in Wando coastal area. These results suggest DIP in Mokpo and DIN and DIP in Wando might be limited at the increase of phytoplankton.

The Development of Multi-Blades I.G.G Blower for Shipbuilding & Ocean (조선/해양용 다단 블레이드 I.G.G 블로워의 개발)

  • Jang, Sung-Cheol;Park, Rae-Bang;Hur, Nam-Soo
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.21 no.3
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    • pp.446-450
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    • 2012
  • I.G.G is abbreviation for inert gas generator high temperature in cargo tank it desulfurize, exhaust and froze the gas that combined brimstone element and soot, then supply inert gas by blower and mack tank inside incombustible range this is equipment that nip in the bud the explosion. The blower for suppling inactivated gas has big impeller with heavy weight to achieve the high pressure, it causes a delay for first operation time and too much load is delivered to motor, total destruction by fire of motor is happen frequently. On this research, we will reduce the size and weight of impeller and install it with several stage, it makes an effect for reducing the first operation time. We also intend to contribute to efficient I.G.G. blower design by research a flow rate and pressure specialty from the diameter of impeller number of blades and size of casing.

Summer Pattern of Phytoplankton Distribution at a Station in Jangmok Bay

  • Lee, Won-Je;Shin, Kyoung-Soon;Jang, Pung-Guk;Jang, Min-Chul;Park, Nam-Joo
    • Ocean Science Journal
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    • v.40 no.3
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    • pp.109-117
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    • 2005
  • Daily changes in phytoplankton abundance and species composition were monitored from July to September 2003 (n=47) to understand which factors control the abundance at a station in Jangmok Bay. During the study, the phytoplankton community was mainly composed of small cell diatoms and dinoflagellates, and the dominant genera were Chaetoceros, Nitzschia, Skeletonema and Thalassionema. Phytoplankton abundance varied significantly from $6.40{\times}10^4$ to $1.22{\times}10^7$ cells/l. The initially high level of phytoplankton abundance was dominated by diatoms, but replacement by dinoflagellates started when the NIP ratio decreased to <5.0. On the basis of the N/P and Si/N ratios, the sampling periofd could be divided into two: an inorganic silicate limitation period (ISLP, $14^{th}$ $July-12^{th}$ of August) and an inorganic nitrogen limitation period (INLP, $13^{th}$ of August - the end of the study). Phosphate might not limit the growth of phytoplankton assemblages in the bay during the study period. This study suggests that phytoplankton abundance and species composition might be affected by the concentrations of inorganic nutrients (N and Si), and provides baseline information for further studies on plankton dynamics in Jangmok Bay.