• Journal of the Microelectronics and Packaging Society
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• v.28 no.4
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• pp.47-50
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• 2021

Nanoimprint lithography (NIL) has revolutionized the fabrications of electronics, photonics, optical and biological devices. Among all the NIL processes, roll-to-roll nanoimprinting is regarded best for having the attributes of low cost, continuous, simple, and energy-efficient process for nanoscale device fabrication. However, large-area printing is limited by the master mold deformation. In this study, a finite element model (FEM) has been constructed to assess the deformation of the roll mold adhesively wrapped on the carbon fiber reinforced material (CFRP) base roll. This study also optimizes the deformations in the metallic roll mold with respect to nip-forces applied in the printing process of nano-fabrication on large scale. The numerical simulations were also conducted to evaluate the deflection in roll mold assembly due to gravity. The results have shown decreasing trend of the deformation with decreasing nip-force. Also, pressure uniformity of about 40% has been optimized by using the current numerical model along with an acceptable deflection value in the vertical axis due to gravity.

• Journal of Microbiology and Biotechnology
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• v.29 no.4
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• pp.651-657
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• 2019

Although smallpox was eradicated in 1980, it is still considered a potential agent of biowarfare and bioterrorism. Smallpox has the potential for high mortality rates along with a major public health impact, eventually causing public panic and social disruption. Passive administration of neutralizing monoclonal antibodies (mAbs) is an effective intervention for various adverse reactions caused by vaccination and the unpredictable nature of emerging and bioterrorist-related infections. Currently, vaccinia immune globulin (VIG) is manufactured from vaccinia vaccine-boosted plasma; however, this production method is not ideal because of its limited availability, low specific activity, and risk of contamination with blood-borne infectious agents. To overcome the limitations of VIG production from human plasma, we isolated two human single-chain variable fragments (scFvs), (SC34 and SC212), bound to vaccinia virus (VACV), from a scFv phage library constructed from the B cells of VACV vaccine-boosted volunteers. The scFvs were converted to human IgG1 (VC34 and VC212). These two anti-VACV mAbs were produced in Chinese Hamster Ovary (CHO) DG44 cells. The binding affinities of VC34 and VC212 were estimated by competition ELISA to $IC_{50}$ values of $2{\mu}g/ml$ (13.33 nM) and $22{\mu}g/ml$ (146.67 nM), respectively. Only the VC212 mAb was proven to neutralize the VACV, as evidenced by the plaque reduction neutralization test (PRNT) result with a $PRNT_{50}$ of ~0.16 mg/ml (${\sim}1.07{\mu}M$). This VC212 could serve as a valuable starting material for further development of VACV-neutralizing human immunoglobulin for a prophylactic measure against post-vaccination complications and for post-exposure treatment against smallpox.

• Proceedings of the Korean Society of Laser Processing Conference
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• 2000.11a
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• pp.23-26
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• 2000

This paper introduces a cleaning process for removing submicron-sized particles from NiP hard disk substrates by the liquid-assisted laser cleaning technique. Measurements of cleaning performance and time-resolved optical diagnostics are performed to analyze the physical mechanism of contaminant removal. The results reveal that nanosecond laser pulses are effective for removing the contaminants regardless of the wavelength and that a thermal mechanism involving explosive vaporization of liquid dominates the cleaning process.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2012.10a
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• pp.273-274
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• 2012

• 대한예방의학회:학술대회논문집
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• 2005.10a
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• pp.295-295
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• 2005

• Journal of Environmental Science International
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• v.4 no.2
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• pp.117-120
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• 1995

The comparision of sunshine duration meter was carried out on the roof of Korea Meteorological Research Institude by comparing Pyrheliometer(Eppley NIP model) to sunshine duration meter(Reflection type) during from Nov. 8, 1989 to Feb. 19, 1990. In the observation Period, daily mean sunshine duration time difference of Jordan sunshine duration meter was recorded 0.47hour and Reflect sunshine duration meter was recorded 0.39hour. More than one hour time difference was observed 15 cases by Jordan sunshine duration meter and 11 cases by Reflect sunshine duration meter.

• Electronics and Telecommunications Trends
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• v.19 no.3 s.87
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• pp.117-124
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• 2004

과거의 패킷 필터를 기반으로 하는 단순한 방화벽은 더 이상 지능적인 해커들을 방어할 수 없다. 가트너에 따르면 현재의 방화벽의 기술은 패킷 필터에서 Application Proxy, Stateful Inspection을 거쳐 DPI로 진화하고 있다고 한다. NIDS나 NIPS를 떠오르게 하는 DPI 방식은 차세대 방화벽의 기술로 인정 받고 많은 연구와 개발이 진행되고 있으며, 실제 제품으로도 선보이고 있다. 본 논문에서는 DPI 기술의 정의와 알고리듬, 그리고 발전 방향에 대해서 알아볼 것이다.

• Textile Coloration and Finishing
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• v.13 no.2
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• pp.135-140
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• 2001

Interlace texturing is very useful method to make compound yarns for new synthetic fabrics. In this study, we make the compound ems for peach skin fabric by interlace texturing method. This study surveys relationship between physical properties of interlace textured yarns and process conditions such as air pressure, yarn tension and take-up speed. Nip density, tensile properties and multi-step shrinkage of the various specimens were discussed with process conditions.

• Polymer(Korea)
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• v.32 no.2
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• pp.138-142
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• 2008

Molecularly imprinting technology is an effective method to prepare a synthetic material with a high selectivity to a target molecule. In this study, a molecularly imprinted polymer (MIP) was synthesized via UV-polymerization using theophylline and UV-curable polyester-acrylate resin as a template molecule and a crosslinker, respectively. To elucidate the effects of functional monomer type on the performance of the MIP, each MIP was synthesized using mathacrylic acid, acrylic acid, and acryl amide as functional monomers. Each MIP showed higher rebinding capacity to theophylline than its corresponding non-imprinted polymer (NIP). The MIP synthesized using mathacrylic acid as a functional monomer showed the highest rebinding capacity to theophylline. The selectivity of the MIP was investigated using a solution with caffeine having a very similar structure to theophylline. The binding performance of the MIP to theophylline decreased when distilled water was used as a solvent, which has more polarity than chloroform.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.37 no.3
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• pp.23-32
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• 2005

A change of z-directional structural and surface properties by calendering has a great influence on liquid penetration into a sheet. It could be also important for multi-ply sheet because it contacts liquid dunhg coating or converting process. Therefore, this study was aimed to evaluate of a change of z-directional structure in multi-ply sheet by calendering. To do this, multi-ply sheets were prepared with various raw materials and calendered at the different pressure and temperature conditions. In multi-ply sheet which consisted of one kind of pulp fiber, thickness reductions were higher in top and bottom plies than in middle plies. And in the case of soft nip calender treatment with high temperature, top layer which was in contact with heating roll showed the highest reduction of thickness. Hard nip calender treatment showed U-shaped density profile in z-direction, but compression profile by SNC treatment was dependent on calendering condition. To examine z-directional structure of multi-ply sheet which was composed of different raw material for each layer, CLSM (Confocal Laser Scanning Microscopy) analyses were carried out on cross direction of sheet. It turned out to be a useful tool for investigating z-directional analysis. As a result, variation of thickness reduction in z-direction is dependent on ply structure, compressibility of pulp fiber, and calendering condition.