• Journal of Yeungnam Medical Science
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• v.34 no.1
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• pp.140-145
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• 2017

Glomerulonephritis (GN) is sometimes associated with infective endocarditis (IE). Bartonella endocarditis is difficult to diagnose because it is rare and cannot be detected by blood culture. This is the first report of cytoplasmic anti-neutrophil cytoplasmic antibody-positive subacute endocarditis-associated GN caused by Bartonella infection in South Korea. A 67-year-old man was hospitalized due to azotemia. He complained of weight loss and anorexia for 6 months. A diagnosis of IE was made based upon echocardiographic detection of vegetations on the mitral and aortic valves and a Bartonella antibody titer of 1:2,048. Renal histology identified focal crescentic GN. Azotemia and proteinuria improved after doxycycline and rifampin treatment combining with steroid therapy.

• Journal of Microbiology and Biotechnology
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• v.27 no.6
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• pp.1065-1070
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• 2017

This study aimed to examine the anti-candidal efficacy of a novel ketone derivative isolated from Diaporthe sp. ED2, an endophytic fungus residing in medicinal herb Orthosiphon stamieus Benth. The ethyl acetate extract of the fungal culture was separated by open column and reverse phase high-performance liquid chromatography (HPLC). The eluent at retention time 5.64 min in the HPLC system was the only compound that exhibited anti-candidal activity on Kirby-Bauer assay. The structure of the compound was also elucidated by nuclear magnetic resonance and spectroscopy techniques. The purified anti-candidal compound was obtained as a colorless solid and characterized as 3-hydroxy-5-methoxyhex-5-ene-2,4-dione. On broth microdilution assay, the compound also exhibited fungicidal activity on a clinical strain of Candida albicans at a minimal inhibitory concentration of $3.1{\mu}g/ml$. The killing kinetic analysis also revealed that the compound was fungicidal against C. albicans in a concentration- and time-dependent manner. The compound was heat-stable up to $70^{\circ}C$, but its anti-candidal activity was affected at pH 2.

• Journal of Communications and Networks
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• v.8 no.2
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• pp.241-252
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• 2006

Traditional service-level agreements (SLAs), defined by average delay or packet loss, often camouflage the instantaneous performance perceived by end-users. We define a set of metrics for service availability to quantify the performance of Internet protocol (IP) backbone networks and capture the impact of routing dynamics on packet forwarding. Given a network topology and its link weights, we propose a novel technique to compute the associated service availability by taking into account transient routing dynamics and operational conditions, such as border gateway protocol (BGP) table size and traffic distributions. Even though there are numerous models for characterizing topologies, none of them provide insights on the expected performance perceived by end customers. Our simulations show that the amount of service disruption experienced by similar networks (i.e., with similar intrinsic properties such as average out-degree or network diameter) could be significantly different, making it imperative to use new metrics for characterizing networks. In the second part of the paper, we derive goodness factors based on service availability viewed from three perspectives: Ingress node (from one node to many destinations), link (traffic traversing a link), and network-wide (across all source-destination pairs). We show how goodness factors can be used in various applications and describe our numerical results.

• Journal of the Microelectronics and Packaging Society
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• v.20 no.4
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• pp.69-74
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• 2013

In this paper, the impact of integrating large number of I/O (Input-Output) and Core power Delivery Network (PDN) on a 6 layers Flip-Chip Ball Grid Array (FCBGA) package is investigated. The impact of core induced supply noise on high-speed I/O interfaces, and high-speed I/O interface's supply noise coupling to adjacent high-speed I/O interfaces' jitter impact are studied. Concurrent stress validation software is used to induce SSO noise on each individual I/O interfaces; and at the same time; periodic noise is introduced from Core PDN into the I/O PDN domain. In order to have the maximum coupling impact, a prototype package is designed to merge the I/O and Core PDN as one while impact on jitter on each I/O interfaces are investigated. In order to understand the impact of the Core to I/O and I/O to I/O noise, the on-die noise measurements were measured and results were compared with the original PDN where each I/O and Core PDN are standalone and isolated are used as a benchmark.

• Natural Product Sciences
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• v.24 no.2
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• pp.88-92
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• 2018

The present study was undertaken to investigate the isolated compounds from the stem bark of Garcinia atroviridis as potential cholinesterase inhibitors and the ligand-enzyme interactions of selected bioactive compounds in silico. The in vitro cholinesterase results showed that quercetin (3) was the most active AChE inhibitor ($12.65{\pm}1.57{\mu}g/ml$) while garcinexanthone G (6) was the most active BChE inhibitor ($18.86{\pm}2.41{\mu}g/ml$). It is noteworthy to note that compound 6 was a selective inhibitor with the selectivity index of 11.82. Molecular insight from docking interaction further substantiate that orientation of compound 6 in the catalytic site which enhanced its binding affinity as compared to other xanthones. The nature of protein-ligand interactions of compound 6 is mainly hydrogen bonding, and the hydroxyl group of compound 6 at C-10 is vital in BChE inhibition activity. Therefore, compound 6 is a notable lead for further drug design and development of BChE selective inhibitor.

• Journal of the Korean Society for Library and Information Science
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• v.41 no.1
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• pp.323-344
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• 2007

This study was carried out for extension of SOMS as metadata of KERIS dCollection to activate IR(institutional repository), which was a new media for academic communication. For this study, current trends of foreign IR were surveyed, and MIT Dspace metadata and Bruxel DISpace metadata were analyzed to apply to SOMS. New SOMS suggested in this study will be more flexible to describe various materials, and to import and/or export academic research performance metadata.

• Korean Journal of Childcare and Education
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• v.12 no.3
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• pp.159-176
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• 2016

The purpose of this study was to provide initial information aboutthe reliability and validity of the Korean version of the BBRS-2(Burks Behaviors Rating Scales, Second Edition). Data were collected for 217 children aged 3-5. K-BBRS-2 consists of a total of 93 questions in 7 factors. The results were as follows. First, internal consistency of the7 factors ranged from 0.81 to 0.94.Results of the confirmatory factor analysis confirmed that the 7-factor model presented in the original tool was the most appropriate. Second, children's maladaptive behavior in Korea based on K-BBRS-2 indicated evidence of validity with a meaningful correlation with children's self-esteem and peer relationships. Third Korean children's maladaptive behavior was not to have significant difference by age of children. The conclusion was that it is not necessary to calculate independent norms for age. Also, when considering gender differences, it was shown that maladaptive behavior appears more in boys than girls. K-BBRS-2 is expected to be utilized as a suitable tool for measuring the maladaptive behavior of Korean children. A nationwide standardized study for Korean children and further research with clinical groups is needed.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.21 no.4
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• pp.413-422
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• 2014

Purpose: The purpose of this study was to identify the nutrition-related factors influencing the prevalence of pressure ulcers among patients admitted to an intensive care unit. Methods: Research participants were 112 patients who were admitted to the ICU of a university hospital. Data were collected through questionnaires which included general characteristics, diet-related characteristics, nutritional status, and pressure ulcer status. Multivariate logistic regression was used to identify independent factors association with prevalence of pressure ulcer Results: The prevalence of pressure ulcers was 58 patients (51.8%) at 10th day after ICU admission. In multivariate analysis, prevalence of pressure ulcers at 10th day in ICU was significantly higher in the nutritional risk group (OR=6.43), malnutrition group (OR=88.02), and deceased serum albumin group (OR=28.83). Conclusion: The results of this research indicate that scores on MNA (Mini Nutritional Assessment) and serum albumin were significant predictors of pressure ulcer prevalence in ICU patients. Therefore, regular MNA-SF and albumin checkups are needed to identify risk for pressure ulcer for ICU patients. In the case of decreased MNA-SF scores and serum albumin levels, more intensive pressure ulcer care is needed for ICU patients.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.11
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• pp.1699-1713
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• 2020

Bovine mastitis, an inflammation of the mammary gland, is the most common disease of dairy cattle causing economic losses due to reduced yield and poor quality of milk. The etiological agents include a variety of gram-positive and gram-negative bacteria, and can be either contagious (e.g., Staphylococcus aureus, Streptococcus agalactiae, Mycoplasma spp.) or environmental (e.g., Escherichia coli, Enterococcus spp., coagulase-negative Staphylococcus, Streptococcus uberis). Improving sanitation such as enhanced milking hygiene, implementation of post-milking teat disinfection, maintenance of milking machines are general measures to prevent new cases of mastitis, but treatment of active mastitis infection is dependant mainly on antibiotics. However, the extensive use of antibiotics increased concerns about emergence of antibiotic-resistant pathogens and that led the dairy industries to reduce the use of antibiotics. Therefore, alternative therapies for prevention and treatment of bovine mastitis, particularly natural products from plants and animals, have been sought. This review provides an overview of bovine mastitis in the aspects of risk factors, control and treatments, and emerging therapeutic alternatives in the control of bovine mastitis.

• Journal of the Korean Society of Costume
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• v.57 no.6 s.115
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• pp.46-61
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• 2007

The analysis of exotic style in domestic fashion brand items aims to offer the ideas necessary for the style and item developments and to analyze exotic images and styles accepted in domestic fashion market. Therefore this study analyzed the domestic fashion brand items and categorized the main exotic factors and styles so that would catch on to its characters and appearance frequency. As for the research method of this study, the frequency and content multi-dimensional analysis were used in the investigation of the exotic images appearing in the domestic fashion brands. The styles of exotic image in domestic fashion brand items are 'natural' style, 'primitive' style, 'ethnic' style, and 'maximalism' style. Also, the main exotic factors in each exotic style were composed of a few exotic images such as 'natural', 'primitive', 'ethnic', 'romantic', 'elegance', 'splendid', 'seductive', 'retro', 'traditional', 'classical', 'bohemian', 'vintage', 'kidult', 'artistic', 'extreme compromise', and 'modern'.