• 대한영상의학회지
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• 제83권6호
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• pp.1342-1353
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• 2022

목적 2세대 및 3세대 이중 소스 단일 에너지와 이중 소스 이중 에너지를 이용한 복부 CT의 방사선량과 영상 품질을 비교하였다. 대상과 방법 부분 또는 근치적 신절제술 후 2019년 첫 10개월(2세대 이중 소스 CT)과 2020년 첫 10개월(3세대 이중 소스 CT)에 추적관찰 복부 CT를 시행한 환자들을 대상으로 하였다. 총 320명의 환자를 성별과 체질량지수에 따라 각각 80명씩 4개 그룹으로 나누었다(A, 2세대 이중 소스 단일 에너지 CT; B, 2세대 이중 소스 이중 에너지 CT; C, 3세대 이중 소스 단일 에너지 CT 및 D, 3세대 이중 소스 이중 에너지 CT). 각 그룹 간 방사선량과 영상 품질(객관적, 주관적 품질)을 비교하였다. 결과 3세대 이중 소스 이중 에너지 CT의 평균 신체 크기 특이적 선량 추정값은 2세대 이중 소스 단일 에너지 CT (42.5%, p = 0.013)와 2세대 이중 소스 이중 에너지 CT (46.9%, p = 0.015) 보다 의미 있게 낮았다. 관찰자 간 일치는 전반적인 영상 품질(intraclass correlation coefficient [이하 ICC]: 0.8867) 및 인공물(ICC: 0.9423)에서 높은 일치도를 보였다. 결론 3세대 이중 소스 이중 에너지 CT는 2세대 이중 소스 이중 에너지 CT 및 이중 소스 단일 에너지 CT와 비교하여 높은 영상 품질을 유지하면서 방사선량을 상당히 감소시킨 결과를 보여주었다.

• 대한간호학회지
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• 제16권1호
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• pp.40-48
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• 1986

The purpose of this study was to identify the effect of the Stress Management Education Program (SMEP) on the nurses stress and stress management ability, and to identify the main factors affecting them. The subjects were 72 nurses who participated in the In-Service education program of the Jin-Ju District, Kyeong-Nam Branch of the Korean Nurses Association during the period from Oct. 1 to Nov. 30, 1985. The book of“The stress management education program”was developed by the investigators. With this book, we executed the 1st education through the lecture & showing an example, After 15 days from the 1st education, we mailed a reminding booklet to the individuals. (2nd education). Then, we mailed a questionnaire on 15th day from the 2nd education. Before and after the SMEP We measured the stress management ability & stress, and identified the affecting factors. Findings of this study are as follows ; 1. The 1st hypothesis that“the SMP will increase the. knowledge about the nurses' stress management”was supported (t= -6.60, p <.001) 2. The 2nd hypothesis that“the SMEP will increase the nurses' practice about the stress management”was rejected. 3. The 3rd hypothesis that“the SEMP will decrease the nurses' stress”was rejected. 4. The 4th hypothesis that“the higher the know-ledge about the stress management, the lower the nurses' stress”was rejected. 5. The 5th hypothesis that“the higher the degree of the practice about the stress management, the lower the nurses' stress”was supported. (r= - .2859, p<.05). 6. There were significant correlations between the knowledge about stress management and age (r= -.3717, p<.01), between the knowledge about stress management and the period of her work. (r= -.2897, p<0.5). There was significant difference in the knowledge about stress management between those who had married and those who had not. (t=2.82, p<.01) 7. There was significant difference in the practice about the stress management between those who had religion and those who had not. (t=2.7, p< .01) 8. There was significant difference in the stress according to the type or work. (t=6. 127, P <.05) There was significant correlation between the stress and supportive system. (r=-.2647, p<.05).

• International Journal of Industrial Entomology and Biomaterials
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• 제19권2호
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• pp.221-228
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• 2009

Nosema sp. infection in the Indian tasar silkworm, Antheraea mylitta exerts a complex of influences on its host. The instar duration was extended significantly (P<0.001) except in $1^{st}$ instar. The infected larvae took about 48 days to reach the spinning stage against 40 days in the uninfected ones. The final weight attained by the larva at the end of each instar of development declined significantly following infection, as did weight gain and relative growth rate (RGR). The growth recorded/ day declined in infected larvae compared to uninfected ones from 8.2% during $1^{st}$ instar to 43.3% during $5^{th}$ instar. Food ingestion and digestion increased with advancement of the instar significantly irrespective of the status of the larvae but the relative consumption rate (RCR) declined. These parameters significantly declined in infected larvae (except food digested during $2^{nd}$ instar). The decline was more during $3^{rd}$ instar. In contrast, the approximate digestibility (AD %) was significantly higher in infected larvae than uninfected ones leaving the $1^{st}$ instar larvae unaffected. The efficiency of conversion of ingested food (ECI) and efficiency of conversion of digested food (ECD) did not change in a patterned way following the microsporidia (Nosema sp.) infection. The values of ECI significantly changed during $2^{nd}$, $3^{rd}$ and $5^{th}$ instars; while the change in ECD during $2^{nd}$, $4^{th}$ and $5^{th}$ were significant. During the entire larval life all the parameters tends to decline significantly following microsporidia infection but AD registered a significant increase. Nosema sp. spore concentration has increased 270.7 times during larval development in the course of experimentation.

• 한국해양공학회지
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• 제28권4호
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• pp.314-323
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• 2014

In this study, a gearbox and blade were modeled in the MASTA program, and the housing and carrier components were modeled using a finite element method. Using substructure synthesis, all the components were combined and used to establish a vibration model of a 2.5-MW wind turbine gearbox. In addition, the safety displacement factor was evaluated using an AGMA data sheet about bearing's outer race for the input shaft and output shaft. As a result, the bearing's outer race for the input shaft, and the radial and axial responses were satisfied by the $1^{st}$ and $2^{nd}$ planetary gears and the $3^{nd}$ helical gear transmission error(TE), respectively. However, the output shaft support bearing's outer race responses were not satisfied with the radial response by the $2^{nd}$ TE and axial response by the $3^{rd}$ TE. To reduce the vibration, tooth modification was needed. After profile tooth modification, at the outer race of the output shaft support bearing, the radial response was reduced by approximately $20{\mu}m$, and the axial response was reduced by approximately $6{\mu}m$.

• 대한한의학회지
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• 제30권3호
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• pp.15-27
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• 2009

Objective : This study was carried to identify the anatomical component of BMM (Foot Taeyang Meridian Muscle in the human truncus), and further to help the accurate application to real acupunctuation. Methods: The human truncus was stripped off in order to demonstrate muscles, nerves and other components, and to display the internal structure of the BMM, dividing into outer, middle, and inner parts. Results: The BMM in the human truncus is composed of muscles, nerves, ligaments etc. The internal composition of the BMM in the human truncus is as follows: 1. Muscle A. Outer layer: medial palpebral ligament, orbicularis oculi, frontalis, galea aponeurotica, occipitalis, trapezius, latissimus dorsi, thoracolumbar fascia, gluteus maximus. B. Middle layer: frontalis, semispinalis capitis, rhomboideus minor, serratus posterior superior, splenius cervicis, rhomboideus major, latissimus dorsi, serratus posterior inferior, levator ani. C. Inner layer: medial rectus, superior oblique, rectus capitis, spinalis, rotatores thoracis, longissimus, longissimus muscle tendon, longissimus muscle tendon, multifidus, rotatores lumbaris, lateral intertransversi, iliolumbaris, posterior sacroiliac ligament, iliocostalis, sacrotuberous ligament, sacrospinous ligament. 2. Nerve A. Outer layer: infratrochlear nerve, supraorbital n., supratrochlear n., temporal branch of facial n., auriculotemporal n., branch of greater occipital n., 3rd occipital n., dorsal ramus of 1st, 2nd, 3rd, 4th, 5th, 6th, 7th, 8th, 9th, 10th, 11th, 12th thoracic n., dorsal ramus of 1st, 2nd, 3rd, 4th, 5th lumbar n., dorsal ramus of 1st, 2nd, 3rd, 4th, 5th sacral n. B. Middle layer: accessory nerve, anicoccygeal n. C. Inner layer: branch of ophthalmic nerve, trochlear n., greater occipital n., coccygeal n., Conclusions : This study shows that BMM is composed of the muscle and the related nerves and there are some differences from already established studies from the viewpoint of constituent elements of BMM at the truncus, and also in aspect of substantial assay method. In human anatomy, there are some conceptional differences between terms (that is, nerves which control muscles of BMM and those which pass near by BMM).

• International Journal of Oral Biology
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• 제41권4호
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• pp.191-197
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• 2016

The present study was to evaluate effects of vitamin E on intravenous administration of lidocaine-induced antinociception. Experiments were carried out using male Sprague-Dawley rats. Orofacial formalin-induced nociceptive behavioral responses were used as the orofacial animal pain model. Subcutaneous injection of formalin produced significant nociceptive scratching behavior. Intraperitoneal injection of 5 and 10 mg/kg of lidocaine attenuated formalin-induced nociceptive behavior in the 2nd phase, compared to the vehicle-treated group. Intraperitoneal injection of 1 g/kg of vitamin E also attenuated the formalin-induced nociceptive behavior in the 2nd phase, compared to the vehicle-treated group. However, low dose of vitamin E (0.5 g/kg) did not affect the nociceptive behavioral responses produced by subcutaneous injection of formalin. The present study also investigated effects of intraperitoneal injection of both vitamin E and lidocaine on orofacial formalin-induced behavioral responses. Vehicle treatment affected neither formalin-induced behavioral responses nor lidocaine-induced antinociceptive effects. However, intraperitoneal injection of 0.5 g/kg of vitamin E enhanced the lidocaine-induced antinociceptive effects in the 2nd phase compared to the vehicle-treated group. Intraperitoneal injection of naloxone, an opioid receptor antagonist, did not affect antinociception produced by intraperitoneal injections of both vitamin E and lidocaine. These results suggest that treatment with vitamin E enhances the systemic treatment with lidocaine-induced antinociception and reduces side effects when systemically treated with lidocaine. Therefore, the combined treatment with vitamin E and lidocaine is a potential therapeutic for chronic orofacial pain.

• 한국작물학회지
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• 제32권1호
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• pp.5-9
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• 1987

벼 상위절 분얼발생양상을 검토하기 위하여 1983년에는 벼 생태형 및 품종별로 조사하였고, 1984년에는 다수계품종을 공시하여 시비수준에 따른 영향을 검토한 결과를 요약하면 다음과 같다. 1. 벼 상위절 분얼양상은 사위 제 2절 제 3절 그리고 제2, 3절에서 동시 발생하는 3가지 유형으로 분류할 수 있었다. 2. 벼 생태형 및 품종에 따른 상위절분얼 정도는 다수계 품종이 일반계 품종보다 높았고, 조생종품종이 중만생종 품종보다 높았다. 3 벼 상위절 분얼 경율과 본답 이앙으로부터 출수까지 일수와는 부의 유의 상관이 인정되었으며, 제2절의 병각회와도 부의 유의상관이 인정되었다. 4. 시비수준에 따른 벼 상위별 분얼 발생정도는 무비재배조건이 보비(N -P$_2$O$_{5}$ -K$_2$O=15-11-13kg/10a) 및 다비(N-P$_2$O$_{5}$ -K$_2$O=25-15-18kg/10a) 조건보다 높았다.높았다.

• 한국가금학회:학술대회논문집
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• 한국가금학회 2003년도 춘계심포지움 Proceedings
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• pp.73-82
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• 2003

본 연구에서는 국내 종계의 생산성 저하요인들을 평가·분석하였으며, 국내사육 종계의 실질적인 생산성을 극대화 시킬 수 있는 방안을 제시하고자 시험을 수행하여 다음과 같은 결론을 얻었다. 1. 혈청검색에 의한 품종별 종게군 질병 모니터링을 실시 한 결과, SE, MS 등 2종의 난계대성 세균성 질병과 REV, APV, CAV, ORT, REO 등 5종의 만성소모성 질병을 유발하는 질병이 종계군의 산란기에 감염되어 이들이 단독 또는 중복감염되어 나타나는 피해가 예상되었으며, 이들의 감염을 효과적으로 예방 할 수 있는 백신의 개발 및 도입의 필요성이 대두되었다. 2. 집중관리 모니터링 대상농장에 대한 ND, IB, IBD 등 3종의 생독백신에 대한 접종효능을 평가해 본 결과 산란종계, 육용종계를 막론하고 전반적으로 니플급수기를 이용한 음수접종법 적용시 5주령 이하 계군에 2내지 3회의 음수접종을 실시하였음에도 불구하고 항체가 거의 형성되지 못하거나 매우 불균일한 면역반응이 나타나는 것으로 조사되어 국내 야외농장에 대한 분무접종 유도 등 기존의 백신접종법에 대한 시급한 개선대책 마련이 요구되었다. 3. 육성기 및 산란기 종계 질병·위생관리 프로그램 확립을 위하여 ND, IB, IBD에 대한 개선된 백신접종 프로그램을 모델계군에 적용한 후, 주령별로 생독백신 접종효능을 조사한 결과 백신접종 후 ND, IB, IBD에 대한 평균 항체가와 항체의 균일도 (%CV)가 표준 목표치 이상 상승하여 개선의 효과를 볼 수 있었다. 4. 산란기 종계 질병·위생관리 프로그램 확립을 위하여 실시된 변이형 IB에 대한 방어능 시험결과 정기적인 Mass type IB 생독백신의 분무접종은 국내 유행 호흡기형 IBV 유전형 VI에 대한 방어효과는 다소 떨어지는 것으로 조사되어 국내분리주를 이용한 IB 생독백신의 개발이 요구되었다. 5. 종계장 살모넬라 및 마이코플라즈마 조기 검출을 위하여 실시한 종계장 살모넬라 및 마이코플라즈마 환경 모니터링 실시 결과 기존의 평판응집반응이나 ELISA에 의한 혈청검색법에 비하여 검출효율이 매우 높은 것으로 조사되어 향후 국내 종게군에 대한 살모넬라 및 마이코플라즈마 조기검출과 방제연구에 큰 도움이 될 것으로 사료되었다.

• Plant Biotechnology Reports
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• 제4권4호
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• pp.329-334
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• 2010

Multiple sequence alignments showed that the prolines at the 25th, 129th, 153rd, 242nd, 322nd, and 434th amino acids in 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) from Agrobacterium sp. strain CP4 are strongly conserved in various prokaryotic EPSPS proteins. Single point mutations of the conserved prolines to alanine (P25A, P153A, P242A, P322A, and P434A) were introduced in the CP4 EPSPS in order to investigate the importance of the conserved prolines for the enzyme properties. The point mutations caused decreases in substrate binding affinity and catalytic efficiency as well as the glyphosate resistance, in general. Especially, the 25th and 242nd prolines located in the polypeptide hinges connecting top and bottom domains of CP4 EPSPS as well as the 434th proline at the C-terminus of the enzyme turned out to be crucial for the enzyme activity.

• 한국식품과학회지
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• 제29권5호
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• pp.1067-1070
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• 1997

Chelating sepharose fast flow gel에 $Cu^{2+}$을 고정화시키고 이들과 단백질과의 친화력 정도에 의해서 용출용매를 통해 단백질을 분획하는 방식의 IMAC법을 이용하여 소의 혈장단백질로부터 IgG의 분리를 시도하였다. 대부분의 혈장단백질은 1차(0.01 M $Na_2HPO_4$, 0.5 M NaCl, pH 4.0)와 2차 용출용매(0.01 M imidazol)에 의하여 용출되었으며 역상 chromatography를 이용하여 각 분획의 단백질조성을 조사한 결과, 1차 용출용매에 의해서는 주로 albumin이, 그리고 2차 용출용매에 의해서는 IgG와 transferrin 등이 IMAC column으로부터 용출되었다. 2차 용출용매에 의해 얻어진 분획으로부터 분자량 100 kD이상의 단백질을 한외여과장치를 이용하여 농축하였을 때, IgG가 효과적으로 분리 정제 되었다.