• KSBB Journal
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• 제29권4호
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• pp.263-270
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• 2014

This study reports significant improvement of atopic dermatitis condition as a result of experiment using Xanthium strumarium L. extract (XS-E) at the dorsal skin of induced atopic dermatitis Nc/Nga mice. Skin clinical score has decreased ($2.75{\pm}0.85$, *p<0.05), showing visible change of skin condition. IgE (***p<0.001) and IgG1 ($2522.00{\pm}32.80$, ***p<0.001) in plasma also decreased significantly. mRNA (gene expression) level increased ($RQ=2.75{\pm}0.10$, ***p<0.001) within skin tissue of CD4+CD25+Foxp3+ Treg cell that's activated by XS-E dosage, thereby discovering that there is an effect of suppressing proliferation and viability of Th2 cell, eosinophils, mast cell and inflammatory cell. Upon examining cells permeated with H&E and toluidine blue staining technique, thickness of epidermis and mast cell's permeation decreased, and the result of examining the distribution of CCR 3+ eosinophils within ALN showed that it's level fell down to that of wild type (normal group, NC/Nga-WT). By such results, it is suggested that XS-E is highly effective on atopic dermatitis, and it is considered that continued quantitative research and case study of clinical research such as effect of cell number in individual tissues or change of total cell number are necessary.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1997년도 춘계학술대회 논문집
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• pp.1025-1030
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• 1997

In this study,the procedure of interpolation surface modeling on bicubic spline patch equation and NC machining are presented. The procedure consists of three parts : patch modeling,cutter location data generation,post processing and NC milling machining. For generation of the cutter location data,tangent vectors and units normal vectors on the patch must be calculated. In order to investigate the properties of the interpolation surface created by bicubic spline patch, two kinds of end conditions, clamped end condition and relaxed end condition,were applied in this study. The shape of the patch depends on the magnitide of the tangent vectors and twist vectors at the corners of bicubic surface patch. the patch generated by relaxed end condition more approximated to the surface patch which was given.

• International Journal of Industrial Entomology and Biomaterials
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• 제27권2호
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• pp.289-297
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• 2013

This study was evaluated the antiatopic activity of silkworm feces extracts in DNCBinduced NC/Nga atopy mice. It was found that each level of IgE and histamine in blood was significantly decreased in the silkworm feces extracts treatment groups, compared with the DNCB-induced atopy control group. When the silkworm feces extracts was applied to the atopy mice, it could be observed that its skin recovered to normal condition with the skin surface being clean and smooth without any tissue. The results suggest that the application of silkworm feces extracts effect on atopic model through a inhibition of histamine emissions with reducing the levels of blood IgE in NC/Nga atopy mice.

• International Journal of Concrete Structures and Materials
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• 제6권2호
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• pp.65-78
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• 2012

An experimental study was carried out to evaluate fresh properties of a moderately high-strength (high-flowing) self-compacting concrete (SCC) and to investigate shear behavior and performance of deep beams made with SCC. Fresh and hardened properties of normal concrete (NC) and SCC were evaluated. The workability and compacting ability were observed based on casting time and number of surface cavities, respectively. Four-point loading tests on four deep beams (two made with SCC and two with NC) were then conducted to investigate their shear behavior and performance. Shear behavior and performance of beams having two different web reinforcements in shear were systematically investigated in terms of crack pattern, failure mode, and load-deflection response. It was found from the tests that the SCC specimen having a normal shear reinforcement condition exhibited a slightly higher load carrying capacity than the corresponding NC specimen, while the SCC specimen having congested shear reinforcement condition showed a similar load carrying capacity to the corresponding NC specimen. In addition, a comparative study between the present experimental results and theoretical results in accordance with ACI 318 (Building Code Requirements for Reinforced Concrete (ACI 318-89) and Commentary-ACI 318R-89, 1999), Hsu-Mau's explicit method (Hsu, Cem Concr Compos 20:419-435, 1998; Mau and Hsu, Struct J Am Concr Inst 86:516-523, 1989) and strut-and-tie model suggested by Uribe and Alcocer (2002) based on ACI 318 Appendix A (2008) was carried out to assess the applicability of the aforementioned methods to predict the shear strength of SCC specimens.

• 한국융합학회논문지
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• 제9권3호
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• pp.79-90
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• 2018

본 연구의 목적은 긍정 얼굴 자극에 대한 주의의 과정에서 정서 맥락적 배경의 유무에 따라 사회불안성향자들과 정상인 간 차이가 나타나는지 살펴보고자 하는 것이다. 이를 위해 무맥락적 배경에서 긍정 얼굴 자극에 대한 주의 과정을 확인하였고, 다음으로 정서 맥락적 배경이 존재하는 상황에서 동일한 주의 과정을 탐색하였다. D시의 800명의 대학생에게 SADS와 CES-D를 실시하고, 사회불안집단(SA, n=24)과 정상 대조군(NC, n=24)을 선별하였다. 주의 개입과 주의 이탈 두 요소를 측정하기 위해 최초 응시 방향, 최초 응시 시간을 안구 운동 추적을 통해 측정하였다. 그 결과, 사회불안집단의 경우 배경이 없는 상태에서 통제집단에 비해 긍정 얼굴 자극으로부터 더 빠른 주의 이탈이 관찰되었다. 그러나 긍정 얼굴 자극이 긍정 배경 자극 안에 제시되면 사회불안집단과 통제집단 간의 차이가 관찰되지 않았다. 이 결과는 긍정 배경이 사회불안장애성향자의 정서 처리에 영향을 미친다는 것을 시사한다.

• 한국정밀공학회지
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• 제11권1호
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• pp.44-53
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• 1994

We experimented on cutting characteristics-cutting force, behavior of cutting temprature, surface foughness, behavior of chips-under low tempdeature, which generated by liquid nitrogen (77K). The workpieces were freezed to -195 .deg. C and liquid nitrogen was also sprinkled on cutting area in order to increase the efficiency of machining in low temperature. The workpiece was became to -195 .deg. C in 5 minutes, and cutting temperature in CC was lower about 170 .deg. C than NC. The cutting force trended to increase slighty in cooled cutting, but chip thickness was decreased, shear angle was however increased. The form of chips was in good conditions of long or short tubular chips in CC. In CC surface roughness of workpiece was better than NC. In NC surface hardness of chips trended to increase according to increasing of cutting speed, but in CC it trended to decrease. The power spectrum of vertical cutting force trended to increase according to increasing of feed, and in CC it was higher than NC.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 춘계학술대회 논문집
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• pp.141-144
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• 2003

This paper proposes an analytical model of off-line feed rate scheduling to obtain an optimum feed rate for high speed machining. Off-line feed rate scheduling is presented as an advanced technology to regulate cutting forces through change of feed per tooth, which directly affects variation of uncut chip thickness. In this paper, the feed rate scheduling model was developed using a mechanistic cutting force model using cutting-condition-independent coefficients. First, it was verified that cutting force coefficients are not changed with respect to cutting speed. Thus, the feed rate scheduling model using the cutting-condition-independent coefficients can be applied to set the proper feed rates for high speed machining as well as normal machining. Experimental results show that the developed fred rate scheduling model makes it possible to maintain the cutting force at a desired level during high speed machining.

• 한국연초학회지
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• 제23권2호
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• pp.109-114
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• 2001

A CAB cDNA vector(pKGCAB), encoding the light harvesting chlorophyll a/b binding protein in Korean ginseng (Panax ginseng C. A. Meyer), was constructed with the CaMV35S promoter of plant expression vector. The chimeric vector was transformed into tobacco(Nicotiana tabacum cv. NC 82) using Agrobacterium tumefaciens LBA 4404 strain, and the transgenic tobacco plant CAB-TP2 was selected. Photosynthetic rates of the CAB-TP2 plant at before-flowering stage were increased about 20% under low irradiance conditions of quantum 100 and 500 $\mu$mol.m$^{-2}$ s$^{-1}$ , however, the rates were similar to those of NC 82 under quantum 1000 and 2000 $\mu$mol.m$^{-2}$ s$^{-1}$ conditions. The plants were germinating under low- or normal irradiance condition and the quantum yield of photosystem III were measured. The differences of the Fv/Em values between conditions were 0.07 and 0.01 in NC 82 and CAB-TP2, respectively. The mature leaves in the position 8-10 of the CAB-TP2 at before-flowering stage revealed l0% higher Fv/Fm values in range of 0.759 to 0.781 and 40% more chlorophyll contents of 70-93mg/$m\ell$ than those of normal NC 82. These data suggest the possibility that the increase in photosynthetic activity of leaves under low light intensity in the canopy of CAB-TP2 transgenic tobacco might lead to increase the quality of lower tobacco leaves.

• 생물정신의학
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• 제16권4호
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• pp.238-245
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• 2009

Objectives : Mild Alzheimer's disease(AD) is uncertain to be related to visuospatial working memory subsystem dysfunction. We used the self ordered pointing test(SOPT) to find the characteristics of visuospatial working memory in mild AD. Methods : We compared the visuospatial working memory abilities of 20 patients with mild AD and 20 normal elderly controls(NC) using SOPT, of which stimuli consisted of two stimuli types(A : abstract, C : concrete) and two stimuli numbers(8 and 12). Therefore, working memory was tested using C8, C12, A8, and A12 stimuli conditions in SOPT. Mixed-model ANOVA was conducted with the AD and NC groups as between-subjects factor, with stimuli types and stimuli numbers as the within-subjects factors and with SOPT error rates as the dependent variable. Results : The AD group showed higher error rates in SOPT than the NC group. The NC group showed low error rates in concrete stimuli than in abstract stimuli and in small stimuli numbers than in large stimuli numbers. And the AD group showed no differences between stimuli types or stimuli numbers. Conclusion : AD patients showed a poor performance in visuospatial working memory using concrete stimuli. The result suggests that there is a non-transformation from visual input to phonological working memory in AD. Patients with AD showed a poor performance although in small stimuli number condition of SOPT. It suggests that in AD, visuospatial working memory is not working well although in low central executive loads.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1994년도 추계학술대회 논문집
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• pp.32-37
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• 1994

We experimented on cutting characteristics - cutting force, behavior of cutting temperature, surface roughness, behavior of chips-under low temperature,which generated by liquid nitrogen(77K). The workpieces were freezed to -195 .deg. C and liquid nitrogen was also sprinkled on cutting area in order to increase the efficiency of machining in low temperature. The workpiece was became to -195 .deg. C in 5 minutes. In cooled condition(CC) surface roughness of workpiece was better than normal condition(NC). In addition, we investigated the possibility that surface roughness of workpiece and shear angle can be predicted analyzing cutting condititions by the trained neural network.