• International Journal of Internet, Broadcasting and Communication
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• v.13 no.1
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• pp.243-248
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• 2021

Although many different types of covert channels have been suggested in the literature, there are little work in directly applying game theory to building up covert channel. This is because researchers have mainly focused on tailoring game theory for covert channel analysis, identification, and covert channel problem solving. Unlike typical adaptation of game theory to covert channel, we show that game theory can be utilized to establish a new type of covert channel in IoT devices. More specifically, we propose a covert channel that can be constructed by utilizing the Nash Equilibrium with sensor data collected from IoT devices. For covert channel construction, we set random seed to the value of sensor data and make payoff from random number created by running pseudo random number generator with the configured random seed. We generate I × J (I ≥ 2, J ≥ 2) matrix game with these generated payoffs and attempt to obtain the Nash Equilibrium. Covert channel construction method is distinctly determined in accordance with whether or not to acquire the Nash Equilibrium.

• Journal of Ginseng Research
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• v.48 no.2
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• pp.122-128
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• 2024

Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease characterized by hepatic fat accumulation, while nonalcoholic steatohepatitis (NASH) is an advanced form of NAFLD characterized by hepatic inflammation, fibrosis, and liver injury, resulting in liver cirrhosis and hepatocellular carcinoma (HCC). Given the evidence that ginseng and its major bioactive components, ginsenosides, have potent anti-adipogenic, anti-inflammatory, anti-oxidative, and anti-fibrogenic effects, the pharmacological effect of ginseng and ginsenosides on NAFLD and NASH is noteworthy. Furthermore, numerous studies have successfully demonstrated the protective effect of ginseng on these diseases, as well as the underlying mechanisms in animal disease models and cells, such as hepatocytes and macrophages. This review discusses recent studies that explore the pharmacological roles of ginseng and ginsenosides in NAFLD and NASH and highlights their potential as agents to prevent and treat NAFLD, NASH, and liver diseases caused by hepatic steatosis and inflammation.

• Water for future
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• v.19 no.4
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• pp.347-354
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• 1986

To predict flood runoff from rainfall and watershed Characteristics, Nash's parameters of N, K are needed to be determined. Also parameters of IUH N and K are derived by the moment method. Nash's model whose parameters are derived from rainfall characteristics is applied to the Wi-stream basin, which is a tributary located in the Nakdong river. For the derivation of IUH by applying linear conceptual model, the storage constant, K, with the rainfall characteristics was adopted as K=1.327 $$.$$$.$$$.$$$.$$$.$$ having a highly significant correlation coefficient, 0.970. Gamma function argumetn, N, derived with such rainfall characteristics was found to be N=0.032$$.$$$.$$$.$$$.$$$.$$ having a highly significant correlation coefficient, 0.970. From the tested results it is proved that Nash's IUH and consequently flood runoff can be predicted from rainfall characteristics.

• Journal of Korean Society of Transportation
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• v.23 no.4 s.82
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• pp.37-45
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• 2005

This paper presents a relationship between Nash bargaining game and Wardrop user equilibrium, which has been widely used in transportation modeling for route choice problem. Wardrop user equilibrium assumes that drivers in road network have perfect information on the traffic conditions and they choose their optimal paths without cooperation each other. In this regards, if the bargaining game process is introduced in route choice modeling, we may avoid the strong assumptions to some extent. For such purpose, this paper derives a theorem that Nash bargaining solution is equivalent to Wardrop user equilibrium as the barging process continues and prove it with some numerical examples. The model is formulated based on two-person bargaining game. and n-person game is remained for next work.

• Journal of Korea Water Resources Association
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• v.42 no.3
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• pp.235-246
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• 2009

This study theoretically reviews the basin storage coefficient and concentration time using the Nash model, a simple unit hydrograph theory. First, the storage coefficient and concentration time of Nash instantaneous unit hydrograph (IUH) are derived based on their definitions, whose characteristics as well as their relationship are also reviewed. Additionally, several empirical equations of storage coefficient and concentration time commonly used in Korea are evaluated by comparing them with those for the Nash IUH. Major results of this study are summarized as follows. (1) The concentration time of Nash IUH is approximately linearly proportional to the number of linear reservoirs, but the storage coefficient non-linearly to the square root. That is, if increasing the number of linear reservoirs by four times, the concentration time becomes also increased by about four times, but the storage coefficient only about two times. This result has a special meaning to understand the effect of basin subdivision on the concentration time and storage coefficient. (2) The storage coefficient and concentration time of Nash IUH are not independent each other, so their independent estimation does not make any physical sense. As the concentration time among the two is more sensitive to the number of linear reservoirs, which should be estimated first, then the storage coefficient considering the concentration time estimated. (3) Empirical equations of concentration time can be divided into two groups, one following the linear channel theory and the other not, whose equation forms are also found to be very similar. This result indicates that the characteristic factors dominating the concentration time are very similar, indicating the possibility of its regionalization over a basin with consistent equation forms. (4) Those for storage coefficient like the Russell formulae are found to consider the physical characteristics of a basin, so their unreasonable applications could sufficiently be excluded.

• Proceedings of the Korea Water Resources Association Conference
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• 1995.05a
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• pp.467-471
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• 1995

• Journal of Korean Society of Transportation
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• v.22 no.7 s.78
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• pp.99-106
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• 2004

This paper presents some comparisons between Cournot-Nash and Stackelberg game in bi-level program, composed of both upper level program and lower level one. The upper level can be formulated to optimize a specific objective function, while the lower formulated to express travelers' behavior patterns corresponding to the design parameter of upper level problem. This kind of hi-level program is to determine a design parameter, which leads the road network to an optimal state. Bi-level program includes traffic signal control, traffic information provision, congestion charge and new transportation mode introduction as well as road expansion. From the view point of game theory, many existing algorithms for bi-level program such as IOA (Iterative Optimization Assignment) or IEA (Iterative Estimation Assignment) belong to Cournot-Nash game. But sensitivity-based algorithms belongs to Stackelberg one because they consider the reaction of the lower level program. These two game models would be compared by using an example network and show some results that there is no superiority between the models in deterministic case, but in stochastic case Stackelberg approach is better than that of Cournot-Nash one as we expect.

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.1762-1767
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• 2007

일반적으로 유역의 대표단위도 산정에는 적용의 간편성을 이유로 수평직선분리법을 주로 사용하여 왔으며 이를 단기호우사상에 대한 모의에 적용해 왔다. 그러나 수평직선분리법에 의한 기저유량의 산출은 연구자의 주관성이 반영될 수 있는 가능성이 다분하며 총유출에 대한 기저유출의 기여가 상대적으로 크게 되는 장기유출모의에 대해서는 그 신뢰도가 떨어진다고 할 수 있다. 따라서 장기유출모의에서는 신뢰성있는 기저유출분리를 통한 합리적인 대표단위도를 유도하는 것이 필요하다. 또한 이 같은 문제점을 개선하기 위해 본 연구에서는 USGS(U.S GEOLOGICAL SURVEY)에서 개발한 기저유출분리 프로그램인 PART(stream flow Partitioning)를 이용하여 기저유출을 분리하고 Nash 모형을 이용하여 유역의 대표단위도를 유도했으며 검증을 위해 강우-유출 모형인 HEC-HMS에 유도된 대표단위도와 합성단위도를 적용하여 실제유출량에 대한 통계분석을 실시하였다. 그 결과 Nash모형의 매개변수를 n은 6.4, K는 0.33으로 산정할 수 있었고, PART에 의해 기저유출을 분리하여 유도된 단위도가 수평직선분리법에 의해 유도된 대표단위도 보다 장기유출모의에서 더 우수한 결과를 보였다. 또한 실측유출량과 모의유출량의 첨두값에 대한 오차도 PART에 의한 방법이 더 작음을 알 수 있었다.

• The Korean Journal of Physiology and Pharmacology
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• v.23 no.6
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• pp.459-466
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• 2019

Dipeptidyl peptidase (DPP)-4 inhibitors, or gliptins, are a class of oral hypoglycemic drugs that have been widely used as a second-line treatment for type 2 diabetes. Gliptins, which were introduced for clinical use a decade ago, have been shown to be beneficial against nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NASH) in animals and humans. Cenicriviroc (CVC), a dual antagonist of C-C chemokine receptor type 2 and 5, is currently under investigation against NASH and fibrosis. It was previously discovered that evogliptin (EVO) reduces hepatic steatosis in diet-induced obese animals but the effectiveness of EVO on NASH remains unexplored. Here, we compared the effectiveness of EVO and CVC against NASH and fibrosis in mice fed a high-fat and high-fructose diet (HFHF). Biochemical and histological analyses showed that mice fed a HFHF for 20 weeks developed severe hepatic steatosis and inflammation with mild fibrosis. Administration of EVO (0.2% wt/wt) for the last 8 weeks of HFHF feeding significantly reduced hepatic triglyceride accumulation, inflammation, and fibrosis as well as restored insulin sensitivity, as evidenced by lowered plasma insulin levels and the improvement in insulin tolerance test curves. Treatment of mice with CVC (0.1% wt/wt) inhibited hepatic inflammation and fibrogenesis with similar efficacy to that of EVO, without affecting hepatic steatosis. CVC treatment also reduced plasma insulin concentrations, despite no improvement in insulin tolerance. In conclusion, EVO administration efficiently ameliorated the development of NASH and fibrosis in HFHF-fed mice, corroborating its therapeutic potential.

• Journal of Yeungnam Medical Science
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• v.36 no.2
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• pp.67-77
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• 2019

The paradigm of chronic liver diseases has been shifting. Although hepatitis B and C viral infections are still the main causes of liver cirrhosis and hepatocellular carcinoma (HCC), the introduction of effective antiviral drugs may control or cure them in the near future. In contrast, the burden of nonalcoholic fatty liver disease (NAFLD) has been increasing for decades, and 25 to 30% of the general population in Korea is estimated to have NAFLD. Over 10% of NAFLD patients may have nonalcoholic steatohepatitis (NASH), a severe form of NAFLD. NASH can progress to cirrhosis and HCC. NASH is currently the second leading cause to be placed on the liver transplantation list in the United States. NAFLD is associated with obesity, type 2 diabetes, dyslipidemia, and metabolic syndrome. The pathophysiology is complex and associated with lipotoxicity, inflammatory cytokines, apoptosis, and insulin resistance. The only proven effective treatment is weight reduction by diet and exercise. However, this may not be effective for advanced fibrosis or cirrhosis. Therefore, effective drugs are urgently needed for treating these conditions. Unfortunately, no drugs have been approved for the treatment of NASH. Many pharmaceutical companies are trying to develop new drugs for the treatment of NASH. Some of them are in phase 2 or 3 clinical trials. Here, pharmacologic therapies in clinical trials, as well as the basic principles of drug therapy, will be reviewed, focusing on pathophysiology.