• Title/Summary/Keyword: N.$D_L$

Search Result 2,655, Processing Time 0.041 seconds

Somatic Embryogenesis and Plant Regeneration in Leaf Explant Cultures of Gentiana scabra var buergeri (용담(Gentina scabra var. buergeri)의 잎 절편 배양에서 체세포배발생에 의한 식물체 재분화)

  • 방재욱;이미경;정성현
    • Korean Journal of Plant Tissue Culture
    • /
    • v.21 no.4
    • /
    • pp.233-237
    • /
    • 1994
  • Plant regeneration system via somatic embryogenesis in leaf explant cultures of Gentiana scabra var. buergeri has been established. Leaf segments formed calli when cultured on MS medium supplemented with 0.5 mg/L 2,4-D and 2 mg/L BAP After transferred to SH medium supplemented with 0.5 mg/L 2,4-D, 2 mg/L CPA and 0.5 mg/L kinetin, the callus became embryogenic. The embryogenic callus was subcultured every 3 to 4 weeks. Upon transfer onto SH basal medium the embryogenic callus gave rise to numerous somatic embryos, which subsequently developed into plantlets. The regenerated plants were potted in an artificial soil with mixture (peatmoss : pearlite : vermiculite : 2 : 1 : 1) and transplanted to the soil after kept under a high humidity for two weeks. A total of 78 plants out of 105 regenerated plants survived in the soil. Phenotypic variations in height, number of stems and the flowering time were observed in tile regenerated plants. Cytogenetical analyses showed no chromosomal variation.

  • PDF

NO Synthase Activities and Methylarginines Contents in the Pancreatic Tissues of Various Animals (수종동물의 췌장조직내 NO Synthase 활성도 및 Methylarginines 함량)

  • Kim, Yong-Kee;Park, Seung-Hee;Nam, Suk-Woo;Seo, Dong-Wan;Hong, Sung-Youl;Lee, Hyang-Woo
    • YAKHAK HOEJI
    • /
    • v.38 no.2
    • /
    • pp.184-190
    • /
    • 1994
  • The activities of nitric oxide synthase and the contents of methylarginines were investigated in the pancreatic tissues of various animals by citrulline-forming method and HPLC, respectively. The high level of in vitro NO synthase activity was detected in chicken pancreas whereas MMA, the strong competitive inhibitor for NO synthase, was detected as trace in the same tissue. On the other hand, the low level of NO synthase activity was observed in the porcine pancreas while the contents of MMA were high. However, it was not possible to find any relationship between NO synthase activities and the contents of dimethylarginines at present time. D'MA was equally distributed among the pancreatic tissues of various animals but DMA was not.

  • PDF

Kato's Inequalities for Degenerate Quasilinear Elliptic Operators

  • Horiuchi, Toshio
    • Kyungpook Mathematical Journal
    • /
    • v.48 no.1
    • /
    • pp.15-24
    • /
    • 2008
  • Let $N{\geq}1$ and p > 1. Let ${\Omega}$ be a domain of $\mathbb{R}^N$. In this article we shall establish Kato's inequalities for quasilinear degenerate elliptic operators of the form $A_pu$ = divA(x,$\nabla$u) for $u{\in}K_p({\Omega})$, ), where $K_p({\Omega})$ is an admissible class and $A(x,\xi)\;:\;{\Omega}{\times}\mathbb{R}^N{\rightarrow}\mathbb{R}^N$ is a mapping satisfying some structural conditions. If p = 2 for example, then we have $K_2({\Omega})\;= \;\{u\;{\in}\;L_{loc}^1({\Omega})\;:\;\partial_ju,\;\partial_{j,k}^2u\;{\in}\;L_{loc}^1({\Omega})\;for\;j,k\;=\;1,2,{\cdots},N\}$. Then we shall prove that $A_p{\mid}u{\mid}\;\geq$ (sgn u) $A_pu$ and $A_pu^+\;\geq\;(sgn^+u)^{p-1}\;A_pu$ in D'(${\Omega}$) with $u\;\in\;K_p({\Omega})$. These inequalities are called Kato's inequalities provided that p = 2. The class of operators $A_p$ contains the so-called p-harmonic operators $L_p\;=\;div(\mid{{\nabla}u{\mid}^{p-2}{\nabla}u)$ for $A(x,\xi)={\mid}\xi{\mid}^{p-2}\xi$.

Design and Synthesis of Apio Nucleosides with Exocyclic Methylene Substituent

  • Kwon, Sung-Hee;Moon, Hyung-Ryong;Jeong, Lak-Shin
    • Proceedings of the PSK Conference
    • /
    • 2002.10a
    • /
    • pp.341.1-341.1
    • /
    • 2002
  • Apio nucleosides belong to unique classes of nucleosides in that 4'-hydroxymethyl group moves to 3'-position. Among thse compounds. we found that apio dideoxyadenosine (apio-ddA) exhibited potent antiviral activity and apio-d4A showed potent anti-HCMV activity. Based on thse findings. it was of great interest to design and synthesize Anio nucleoside anlogues with various substituents such as fluorn or azido group. In order to synthesize apio analogues. the glyxosyl dondr. D-. and L-apio sugar acetates were first synthesized. starting from D-gallas. condensed whth silylated N4-benzoylcytosine. and then convenged to the linal D-andL-nucleosides. Synthesist of the D-and-apio nucieosides will be prssented in detail aht th the meeting.

  • PDF

Reduction in the contents of acetaldehyde, methanol and fusel alcohols in the Muscat Bailey A wine fermented by Korean indigenous sugar-tolerant yeasts Saccharomyces cerevisiae S13 and D8 (토착형 아황산 및 당 내성 효모 Saccharomyces cerevisiae S13과 D8에 의한 Muscat Bailey A 포도주의 아세트알데히드, 메탄올 및 고급알코올의 감소 효과)

  • Kim, Mi-Sun;Park, Heui-Dong
    • Food Science and Preservation
    • /
    • v.21 no.6
    • /
    • pp.851-858
    • /
    • 2014
  • Muscat Bailey A (MBA) wine was fermented using the indigenous Korean Saccahromyces cerevisiae strains S13 and D8, and the fermentation characteristics were compared with those of S. cerevisiae W-3, an industrial wine yeast. The strains S13 and D8 showed delayed alcohol fermentation compared with the W-3 strain, but the final alcohol contents of the S13 and D8 wines after fermentation were similar to those of the W-3 wine. The S13 wine showed significantly lower malic-acid content than the W-3 wine, but the D8 wine showed a similar level. Both the wines fermented using the S13 and D8 strains showed significantly lower acetaldehyde, methanol, and fusel oil contents, including n-propanol, iso-butyl alcohol, and iso-amyl alcohol, compared to the W-3 wine. Especially, the methanol content was 98.6 mg/L in the S13 wine and 112.0 mg/L in the D8 wine, which were much lower than 192.8 mg/L in the W-3 wine. The S13 wine obtained the highest score in terms of color among the three wines in the sensory evaluation, with lower Hunter's L, a, and b values compared to the W-3 wine.

On the vibration influence to the running power plant facilities when the foundation excavated of the cautious blasting works. (노천굴착에서 발파진동의 크기를 감량 시키기 위한 정밀파실험식)

  • Huh Ginn
    • Explosives and Blasting
    • /
    • v.9 no.1
    • /
    • pp.3-13
    • /
    • 1991
  • The cautious blasting works had been used with emulsion explosion electric M/S delay caps. Drill depth was from 3m to 6m with Crawler Drill ${\phi}70mm$ on the calcalious sand stone (soft -modelate -semi hard Rock). The total numbers of test blast were 88. Scale distance were induced 15.52-60.32. It was applied to propagation Law in blasting vibration as follows. Propagtion Law in Blasting Vibration $V=K(\frac{D}{W^b})^n$ were V : Peak partical velocity(cm/sec) D : Distance between explosion and recording sites(m) W : Maximum charge per delay-period of eight milliseconds or more (kg) K : Ground transmission constant, empirically determind on the Rocks, Explosive and drilling pattern ets. b : Charge exponents n : Reduced exponents where the quantity $\frac{D}{W^b}$ is known as the scale distance. Above equation is worked by the U.S Bureau of Mines to determine peak particle velocity. The propagation Law can be catagorized in three groups. Cubic root Scaling charge per delay Square root Scaling of charge per delay Site-specific Scaling of charge Per delay Plots of peak particle velocity versus distoance were made on log-log coordinates. The data are grouped by test and P.P.V. The linear grouping of the data permits their representation by an equation of the form ; $V=K(\frac{D}{W^{\frac{1}{3}})^{-n}$ The value of K(41 or 124) and n(1.41 or 1.66) were determined for each set of data by the method of least squores. Statistical tests showed that a common slope, n, could be used for all data of a given components. Charge and reduction exponents carried out by multiple regressional analysis. It's divided into under loom over loom distance because the frequency is verified by the distance from blast site. Empirical equation of cautious blasting vibration is as follows. Over 30m ------- under l00m ${\cdots\cdots\cdots}{\;}41(D/sqrt[2]{W})^{-1.41}{\;}{\cdots\cdots\cdots\cdots\cdots}{\;}A$ Over 100m ${\cdots\cdots\cdots\cdots\cdots}{\;}121(D/sqrt[3]{W})^{-1.66}{\;}{\cdots\cdots\cdots\cdots\cdots}{\;}B$ where ; V is peak particle velocity In cm / sec D is distance in m and W, maximLlm charge weight per day in kg K value on the above equation has to be more specified for further understaring about the effect of explosives, Rock strength. And Drilling pattern on the vibration levels, it is necessary to carry out more tests.

  • PDF

Relationship between Bone Morphological Microstructure and Inflammatory Markers in Growing Mice Fed a High Fat Diet (고지방식이 공급에 따른 성장기 마우스의 골의 형태학적 미세구조와 염증지표 변화)

  • Kim, Mi-Sung;Lee, Hyun-A;Kim, Ok-Jin;Sohn, Cheong-Min
    • Journal of Nutrition and Health
    • /
    • v.44 no.6
    • /
    • pp.481-487
    • /
    • 2011
  • Obesity not only reduces bone mineral density but also increases inflammatory markers. Therefore, we examined the change in inflammatory markers and morphological microstructure of the bones using a mouse model fed a high-fat diet. C57BL/6J 4-week-old male mice were divided into a control group (n = 6) and a experimental group (n = 6); the control group was provided with 10% Kcal fat diet, and the high-fat diet group was provided with 45% Kcal fat diet for 12 weeks using the free provision method. Blood was analyzed for inflammatory markers, and micro-computed tomography was used to measure the morphological microstructure of the femoral bone. The weight increases in the control group and high-fat diet group were $5.85{\pm}1.84g$ and $16.06{\pm}5.64g$, respectively (p < 0.01), glucose was $115.00{\pm}16.88mg/dL$ and $188.33{\pm}13.29mg/dL$ (p < 0.01), and triglycerides were $65.00{\pm}6.19mg/dL$ and $103.33{\pm}8.02mg/dL$ (p < 0.05) respectively. Leptin and interleukin (IL)-6 were significantly higher in the high-fat diet group than that in the control group (p < 0.01). As a result of a biochemical index analysis of bone metabolism, osteocalcin tended to be lower in the high-fat diet group, whereas CTx was significantly higher in the high-fat diet group compared to that in the control group (p < 0.01). The thickness of the bony trabecula was significantly narrower in the high-fat diet group than that in the control group (p < 0.05), and the gap in the bony trabecula was significantly wider in the high-fat diet group than that in the control group (p < 0.05). IL-6 and the gap in the bone trabecula, which was a morphological microstructure of the bones, showed a positive correlation (p < 0.05). Taken together, inducing obesity through a high-fat diet in mice during the growth phase caused a change in bone microstructure and was correlated with the inflammation index. Accordingly, restriction of excessive fat intake may be needed to suppress the inflammatory reactions and promote normal bone formation.

Amelioration of Plasma Glucose and Cholesterol levels in Db/db Mice by a Mixture of Chinese Herbs (Db/db 마우스 모델에 있어서 한약재조성물의 혈당 및 혈장 콜레스테롤 개선효과)

  • Lee, Jai-Heon;Cho, Chang-Woo;Han, Xiang-Fu;Hwang, Ji-Yeon;Kang, Min-Jung;Joo, Hee-Jeong;Kim, Mi-Eun;Seo, Yeong-Ju;Kim, Jung-In
    • Korean Journal of Medicinal Crop Science
    • /
    • v.16 no.4
    • /
    • pp.225-230
    • /
    • 2008
  • Diabetes mellitus is the fifth leading cause of death among Koreans. Control of hyperglycemia and dyslipidemia is strongly correlated with decrease in risks for cardiovascular diseases, the most common and fatal diabetic complication. The effects of chronic feeding of a mixture of Chinese herbs on blood lipid profile were measured in an animal model of type 2 diabetes mellitus, db/db mice (C57BL/Ks). The Chinese herb mixture was composed of Panax ginseng C. A. Meyer,Astragalus membranaceus, Glycyrrhiza uralensis, Lycium chinense, Morus, Pueraria thunbergiana, Prunella vulgaris var. lilacina, Acanthopanax sessiliflorus, Schizandra chinensis, Scutellaria baicalensis, Dioscorea batatas, Polygonatum doratumvar. pluriflorum, Paeonia lactiflora, and Rehmannia glutinosa in a ratio of 1 : 0.7 : 0.4 : 0.7 :0.4 : 0.7 : 1.1 : 0.9 : 0.4 : 0.4 : 0.7 :0.7 : 0.9 : 0.9. Methanol extract of the Chinese herb mixture was tested for the inhibitory activity against yeast ${\alpha}$-glucosidase in vitro. The Chinese herb mixture extract inhibited ${\alpha}$-glucosidase by 25.2% at the concentration of 0.5mg/mL. Four weekold male db/db mice (n = 14) were fed AIN-93G semipurified diet or diet containing 10% powder of the Chinese herb mixture for 6 weeks after 1 week of adaptation period. Body weight (39.5 ${\pm}$ 1.6 g) and food intake (4.3 ${\pm}$ 0.6 g/day) of the Chinese herb group were not significantly different from those of the control group (40.4 ${\pm}$ 2.6 g and 4.5 ${\pm}$ 0.6 g/day). Consumption of Chinese herb mixture significantly decreased plasma glucose level (442.5 ${\pm}$ 36.0mg/dL) compared with the control group (489.8 ${\pm}$ 34.6 mg/dL, p < 0.05). Plasma cholesterol level (159.2 ${\pm}$ 18.4 mg/dL) of the Chinese herb group was significantly lower than that of the control group (185.4 ${\pm}$ 13.7 mg/dL, p < 0.05). Blood glycated hemoglobin (6.3 ${\pm}$ 0.8%) and plasma triglyceride levels (99.4 ${\pm}$ 15.0mg/dL) of the Chinese herb group were not significantly different from those of the control group (6.7 ${\pm}$ 0.7% and 108.8 ${\pm}$ 11.0mg/dL). Thus, the Chinese herb mixture could be useful in the treatment of diabetes and cardiovascular complications of diabetes.

HADAMARD-TYPE FRACTIONAL CALCULUS

  • Anatoly A.Kilbas
    • Journal of the Korean Mathematical Society
    • /
    • v.38 no.6
    • /
    • pp.1191-1204
    • /
    • 2001
  • The paper is devoted to the study of fractional integration and differentiation on a finite interval [a, b] of the real axis in the frame of Hadamard setting. The constructions under consideration generalize the modified integration $\int_{a}^{x}(t/x)^{\mu}f(t)dt/t$ and the modified differentiation ${\delta}+{\mu}({\delta}=xD,D=d/dx)$ with real $\mu$, being taken n times. Conditions are given for such a Hadamard-type fractional integration operator to be bounded in the space $X^{p}_{c}$(a, b) of Lebesgue measurable functions f on $R_{+}=(0,{\infty})$ such that for c${\in}R=(-{\infty}{\infty})$, in particular in the space $L^{p}(0,{\infty})\;(1{\le}{\le}{\infty})$. The existence almost every where is established for the coorresponding Hadamard-type fractional derivative for a function g(x) such that $x^{p}$g(x) have $\delta$ derivatives up to order n-1 on [a, b] and ${\delta}^{n-1}[x^{\mu}$g(x)] is absolutely continuous on [a, b]. Semigroup and reciprocal properties for the above operators are proved.

  • PDF

Derivation of the Expected Busy Period U sing its Pseudo Probability Density Function for a Controllable M/G/l Queueing Model Operating Under the Max (N, T, D) Policy (가상확률밀도함수를 사용하여 Max(N, T, D) 운5방침이 적용되는 조정가능한 M/G/1 대기모형의 busy period의 기대값 유도)

  • Rhee, Hahn-Kyou;Oh, Hyun-Seung
    • Journal of Korean Society of Industrial and Systems Engineering
    • /
    • v.31 no.4
    • /
    • pp.86-92
    • /
    • 2008
  • The expected busy period for the controllable M/G/1 queueing model operating under the triadic Max (N, T, D) policy is derived by using a new concept so called "the pseudo probability density function." In order to justify the proposed approaches for the triadic policy, well-known expected busy periods for the dyadic policies are recovered from the obtained result as special cases.