• Title/Summary/Keyword: N-acetylchitoologosaccharides

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Antitumor Activity of Reaction Mixture of Chitin and Green Onion Extract (키틴과 파추출액 반응물의 항암 작용)

  • Kim, Yeong-Shik;Park, Kyung-Shin;Chang, Il-Moo;Hyun, Jin-Won;Park, Jae-Gahb;Park, Ho-Koon
    • YAKHAK HOEJI
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    • v.38 no.5
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    • pp.579-585
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    • 1994
  • Antitumor activity was tested by administration of reaction mixture of green onion extract and chitin to mice bearing sarcoma-180 cells. An intraperitoneal injection of mixture(20 mg/kg/day) to mice Have an 52% inhibition of tumor growth. Inhibition of tumor growth was found to be dose-dependent. When eighty miligrams of the mixture were administered, the weight of tumor was reduced significantly. HPLC analysis indicated the mixture was composed of N-acetyl-D-glucosamine, N-acetylchitobiose and N-acetylchitotriose.

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