• Perspectives in Nursing Science
• /
• 제9권1호
• /
• pp.51-60
• /
• 2012

Purpose: The purpose of this study was to develop a self-directed e-learning program for ICU nurses and to evaluate how the proposed e-learning program affects the level of knowledge, nursing performance and job satisfaction of ICU nurses. Methods: The e-learning program was developed with the Computer Assisted Instruction Design Model using sources of self-efficacy which included the inactive attainment, vicarious experience, and verbal persuasion of ICU nurses. The program was evaluated by experts. Following the revision of the program, it was applied to a total of 59 ICU nurses (experimental group n=29, control group n=30) from three hospitals. Four weeks later, we measured the level of knowledge, nursing performance and job satisfaction. Results: The level of knowledge significantly improved in the experimental group (t=5.691, p<.001). Moreover, the level of nursing performance significantly increased in the areas of circulatory diagnostic test (t=2.143, p=.039), EKG (t=2.911, p=.006), aortic balloon pump (t=2.491, p=.017), and nebulizer therapy (t=2.085, p=.044). Overall, job satisfaction did not significantly increase (t=1.664, p=.105); however, job satisfaction in terms of relationships with coworkers (t=2.371, p=.023) and the needs of nursing performance (t=2.940, p=.006) were significantly increased. Conclusion: The results showed that the proposed e-learning program using sources of self-efficacy from ICU nurses was an effective learning method to increase the level of knowledge and nursing performance. The propose de-learning program would be a useful teaching tool for ICU nurses improving the quality of ICU patient care.

• Journal of Animal Science and Technology
• /
• 제62권5호
• /
• pp.659-667
• /
• 2020

This study was conducted to evaluate the effects of different levels of crude protein (CP) and protease on nitrogen (N) utilization, nutrient digestibility, and growth performance in growing pigs. A total of six crossbred ([Landrace × Yorkshire] × Duroc) barrows were individually accepted in 1.2 m × 0.7 m × 0.96 m stainless steel metabolism cages. The pigs (average initial body weight of 27.91 ± 1.84 kg) randomly assigned to six diets with six weeks (6 × 6 Latin square design). The experiment was carried out in an environment with a temperature of 23 ± 1.5℃, a relative humidity of 83 ± 2.3% and a wind speed of 0.25 ± 0.03 m/s. The dietary treatments were arranged in a 2 × 3 factorial design with two levels of CP (15.3% or 17.1%) and three levels of protease (0 ppm, 150 ppm, or 300 ppm). The average daily gain and gain to feed ratio (G:F) tended to increase (p = 0.074) with increasing amounts of protease. The low CP level diet reduced (p < 0.050) urinary and fecal N concentrations, the total N excretion in feces, and increased (p < 0.050) N retention. Different protease levels in the diet did not affect (p > 0.05) at N intake, but supplementation of the diets with 300 ppm protease decreased (p < 0.050) the N concentration in urine and feces and tended to increase (p = 0.061) the percentage of N retention retained of the total N intake. The dietary CP level did not affect (p > 0.050) the apparent total tract digestibility (ATTD) of dry matter, digestible energy (DE), and metabolic energy (ME), but diet supplementation with 300 ppm protease showed higher (p < 0.050) ATTD of DE and ME than in the protease-free diet. Therefore, a low protein diet with protease could improve the utilization of nitrogen, thereby reducing the negative effect of N excretion into the environment while maintaining or increasing growth performance compared to a high protein diet.

• The Journal of Korean Physical Therapy
• /
• 제16권2호
• /
• pp.169-180
• /
• 2004

The aim of this study was to investigate the effect of TENS on muscle pain induced by carrageenan. Muscle pain was induced in male Sprague-Dowley rats by intra-muscular injection of gastrocnemius with $3\%$ carrageenan. nNOS was measured to assess the effect of TENS on muscle pain induced by Carrageenan. The lumbar enlargement of the spinal cord was removed in different groups of animals 24 h after induction of muscle pain. The level of nNOS mRNA was measured in the lumbar section of the spinal cord using RT-PCT. The expression of nNOS was analyzed in the dorsal horn of the lumbar spinal cord by immunohistochemistry. TENS decreased nNOS immunoreactivity in the dorsal horn of the lumbar spinal cord when compared with controls(p<.05). In RT-PCR, TENS decreased nNOS mRNA level of lumbar spinal cord when compared with controls(p<.05). These results suggested that application of TENS attributed to decrease muscle pain.

• 전기전자학회논문지
• /
• 제7권1호
• /
• pp.1-8
• /
• 2003

본 논문에서는 고내압 및 고속 스위칭 특성을 갖는 고성능 BCD(Bipolar- CMOS-DMOS) 소자 구조를 고안하였다. 공정 및 소자 시뮬레이션을 통하여, 최적화된 공정 규격과 소자 규격을 설계하였으며, 고안된 소자의 전기적 특성을 만족시키기 위하여 이중 매몰층 구조, 트랜치 격리 공정, n-/p- 드리프트 영역 형성기술 및 얕은 접합 깊이 형성기술 등을 채택하였다. 이 스마트 파워 IC는 20V급 Bipolar npn/pnp 소자, 60V급 LDMOS소자, 수 암페어급의 VDMOS, 20V급 CMOS소자 그리고 5V급 논리 CMOS를 내장하고 있다.

• Asian-Australasian Journal of Animal Sciences
• /
• 제13권7호
• /
• pp.967-973
• /
• 2000

A metabolism trial was conducted with 28 Najdi rams allocated into seven dietary groups to evaluate the effect of dietary inclusion of Salicornia bigelovii Torr biomass on nutrient digestibility, rumina I fluid metabolites and nitrogen and mineral balances. Either the stems (ST) or spikes (SP) of this seawater-irrigated halophyte were incorporated into complete diets at rates of 0, 10, 20 and 30% levels, replacing equal amounts of rhodesgrass hay in a ground mixed control diet. Digestibility of DM, OM, EE, NFE and fecal and urinary nitrogen were not affected by increased level of ST in the diet. As level of ST increased from 0 to 20% in the diets, CP digestibility and nitrogen retention approached their maximum (p<0.01), whereas CF digestibility reached its minimum (p<0.01). On the other hand, except for EE, digestion of all nutrients and nitrogen retention were linearly depressed (p<0.01) as SP increased in the diets from 10 to 30% level. Concentration of ammonia-N, total VFA and pH values in the rumen fluid were lower (p<0.01) with the ST- or SP-fed diets than with the control diet. Increasing level of ST or SP in the diet was associated with an increase (p<0.01) in the proportion of acetate and a decline (p<0.01) in molar percentage of propionate in the ruminal fluid. Sodium absorption increased (p<0.01) with increased ST and SP in the diets up to the 10 and 20% level, respectively, followed by constant absorption values up to the 30% level. When the level of ST in the diet gradually increased to 30%, a concomitant increased (p<0:01) in Ca and P absorption were obvious; whereas, increased level of SP in the diets from 0 to 30% resulted in noticeable (p<0.01) depression in Ca and P apparent absorption.

• 한국토양비료학회지
• /
• 제9권4호
• /
• pp.245-250
• /
• 1976

율무의 재배(裁培)에서 시비량(施肥量)을 결정(決定)하는 기초(基礎) 자료(資料)를 얻기 위하여 포장시험(圃場試驗)을 실시(實施)한 결과(結果)는 다음과 같았다. 1. N, $P_2O_5$, $K_2O$, 를 0-0-0, 6-3-3, 12-6-6 및 18-9-9kg/10a로 증가(增加)시킬 때 율무의 수량(收量)은 직선적(直線的)으로 증가(增加)했다. 2. NPK 중 다른 두 성분의 수준(水準)을 제삼수준(第三水準), 즉 N는 12kg/10a, $P_2O_5$ 및 $K_2O$는 6kg/10a로 고정(固定) 시키고 비료(肥料) 수준별(水準別) 수량(收量)을 보면 NPK의 제삼수준(第三水準)(N는 12kg/10a, $P_2O_5$ 및 $K_2O$는 6kg/10a)에서 최고(最高) 수량(收量)이 되고 그 이상(以上)에서는 수량(收量)이 감소(減少)했다. 3. 따라서 본시험(本試驗)만으로는 율무의 삼요소적량(三要素適量)을 지적(指摘)해 낼 수 없어 시비량(施肥量)을 늘려 새로운 시험(試驗)을 실시(實施)할 필요(必要)가 있다. 그러나 본시험(本試驗)에 쓰인 것과 유사(類似)한 토양(土壤)에서는 N, $P_2O_5$, $K_2O$를 18-9-9 kg/10a 이상(以上) 시용(施用)해도 수량(收量)이 증가(增加)할 수 있음을 알 수 있다. 4. 식물체(植物體)의 N와 K의 흡수면(吸收面)에서는 두 성분(成分) 간(間)에 배항작용(培抗作用)이 있음이 관찰(觀察)됐다.

• Asian-Australasian Journal of Animal Sciences
• /
• 제31권10호
• /
• pp.1643-1653
• /
• 2018

Objective: This study investigated the effect of dietary crude protein (CP) supplementation on nutrient intake, nitrogen (N) utilisation, blood metabolites, ruminal fermentation and growth performance of young Holstein bulls. Methods: Twenty-one young bulls weighing $277{\pm}11.2kg$ were equally divided into three groups and were offered diets formulated with low CP (LCP; 10.21% CP and 4.22% rumen degradable protein [RDP]), medium CP (MCP; 12.35% CP and 5.17% RDP) and high CP (HCP; 14.24% CP and 6.03% RDP). Yellow corn silage was used as a unique forage source and was mixed with concentrate. This mixed feed was given ad libitum to the young bulls included in the study. Results: Results showed that CP intake, blood urea nitrogen, N intake, total N excretion and N balance increased linearly with an increase in dietary CP level (p<0.05). However, no significant difference was observed in nutrient digestibility among the bulls receiving the different diets. Ruminal pH (p<0.05) and ammonia nitrogen ($NH_3-N$) concentration (p<0.01) were significantly higher in the bulls receiving the MCP and HCP diets than in those receiving the LCP diet. The bulls receiving the HCP diet showed significantly higher ruminal bacterial protein level, propionate, acetate and total volatile fatty acid (TVFA) concentrations than bulls receiving the LCP diet (p<0.05). Moreover, dietary CP level exerted a significant positive effect on the final body weight, average daily gain and gain-to-feed ratio of the bulls (p<0.05). Conclusion: High dietary CP level is optimal for achieving maximum growth and high profitability without exerting a negative effect on the physiology of growing Holstein bulls.

• 한국초지조사료학회지
• /
• 제9권2호
• /
• pp.82-87
• /
• 1989

A field experiment was carried out to determine the effects of 11 different application levels of nitrogen (N), phosphorous ($P_2O_5$) and potassium($K_2O$) fertilizer in late-autumn on the winter survival, early spring growth and dry matter(DM) yield, carbohydrate reserves (CHO-R) in stubble of grasses, and botanical composition in orchardgrass dominated existing pasture in Suwon from October, 1987 to May, 1988. Winter survival of grasses was high (ca. 90%) in all N-fertilized plots, regardless of $P_2O_5$ and $K_2O$ application, and those in zero-N and zero-NPK plots were low as 86.5% and 81.4%, respectively. Early spring growth was vigorous in N-fertilized plots. Heading rate at the fist harvest was 80-86% in all N plots, regardless of $P_2O_5$ and $K_2O$, while those in zero-N and zero-NPK plots were very low as 61% and 56%, respectively. The DM yield of first harvest was higher in the plots of N 35 kg(Site B) and N 70kg $ha^{-1}$ (Site A), regardless of $P_2O_5$ and $K_2O$ level, and those in zero-N and zero-NPK plots were very low (p < 0.05). But no significant difference of yield was observed between N 75 kg and N 105 kg. CHO-R in stubble and legumes were high in zero-N and zero-NPK plots, and low relationship was found between winter survival and CHO-R of grasses. Winter survival, early spring growth and DM yield were significantly influenced by N fertilizer. In this experiment, the optimum application level of N in late-autumn could be recommended in 35-70 kg $ha^{-1}$, and no beneficial effects were observed by $P_2O_5$ and $K_2O$ fertilizer.

• 한국축산식품학회지
• /
• 제29권6호
• /
• pp.685-694
• /
• 2009

The aim of the present study was to evaluate the variation in ultimate pH of commercial populations of pure-breed (Landrace, Duroc and Yorkshire) pig's longissimus muscles and their effect on objective meat quality traits and sensory characteristics. Fifty boars were sampled from 184 pigs, which were reared at three breeding farms and slaughtered at a commercial abattoir. The selection was determined based on ultimate pH, and animals were segregated into three groups: low pH (pH $\leq$ 5.5, n=13), medium pH (pH 5.5 to 5.6, n=18) and high pH (pH $\geq$ 5.6, n=16). The breeds had no significant effects; however, pigs with a higher ultimate pH had significantly (p<0.05) higher intramuscular fat content, lower level of polyunsaturated fatty acids, lower level of lipid oxidation and higher eating quality compared to those with lower ultimate pH. As the ultimate pH increased, the relative proportion of C14:0, C16:0 and C18:1 increased while C18:2n6 and C20:4n6 decreased. The present study demonstrates that the economic value of pigs can be characterized by the ultimate pH and/or intramuscular fat content. However, these results do not necessarily indicate that a high ultimate pH directly corresponds to high intramuscular fat content and vice versa.

• Journal of Applied Biological Chemistry
• /
• 제57권1호
• /
• pp.17-22
• /
• 2014

Nardostachys chinensis (N. chinensis) has been used in traditional medicine as a sedative and analgesic. It has been reported that N. chinensis extract has an antioxidant activity. However, the mechanism has not been elucidated. In this study, we showed that FOXO3a was activated by N. chinensis extract. FOXO3a is a transcriptional factor that involved in cell cycle arrest, DNA repair, apoptosis, and detoxification of reactive oxygen spices (ROS). Protein level of FOXO3a was increased by N. chinensis extract whereas phospho-FOXO3a (Thr 32) was not changed. Promoter activities of target genes of FOXO3a such as MnSOD, p27, and GADD45 were increased by N. chinensis extract. Among target genes, protein level of MnSOD was increased by N. chinensis extract, and this leads to removal of ROS level in human embryonic fibroblast (HEF) cells. These results suggested that N. chinensis extract has an antioxidant activity by upregulation of MnSOD through FOXO3a activation.