• Title/Summary/Keyword: N generation

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Complete mitochondrial genome of Nyctalus aviator and phylogenetic analysis of the family Vespertilionidae

  • Lee, Seon-Mi;Lee, Mu-Yeong;Kim, Sun-sook;Kim, Hee-Jong;Jeon, Hye Sook;An, Junghwa
    • Journal of Species Research
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    • v.8 no.3
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    • pp.313-317
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    • 2019
  • Bats influence overall ecosystem health by regulating species diversity and being a major source of zoonotic viruses. Hence, there is a need to elucidate their migration, population structure, and phylogenetic relationship. The complete mitochondrial genome is widely used for studying the genome-level characteristics and phylogenetic relationship of various animals due to its high mutation rate, simple structure, and maternal inheritance. In this study, we determined the complete mitogenome sequence of the bird-like noctule (Nyctalus aviator) by Illumina next-generation sequencing. The sequences obtained were used to reconstruct a phylogenic tree of Vespertilionidae to elucidate the phylogenetic relationship among its members. The mitogenome of N. aviator is 16,863-bp long with a typical vertebrate gene arrangement, consisting of 13 protein-coding genes (PCGs), 22 transfer RNA genes, 2 ribosomal RNA genes, and 1 putative control region. Overall, the nucleotide composition is as follows: 32.3% A, 24.2% C, 14.3% G, and 29.2% T, with a slight AT bias (61.5%). The base composition of the 13 PCGs is as follows: 30.3% A, 13.4% G, 31.0% T, and 25.2% C. The phylogenetic analysis, based on 13 concatenated PCG sequences, infers that N. aviator is closely related to N. noctula with a high bootstrap value (100%).

Consumers' Negative Responses to the Communication Failure of Chatbots in Online Fashion Shopping Malls (온라인 패션 쇼핑몰 챗봇의 커뮤니케이션 실패에 대한 소비자의 부정적 반응)

  • Seo, Min Jeong
    • Fashion & Textile Research Journal
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    • v.24 no.2
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    • pp.183-194
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    • 2022
  • This study aims to understand the consumers' negative responses to communication failure of chatbots caused by their imperfections. Specifically, this study examines 1) the relationship among chatbot's communication failure, dissatisfaction, negative behavior (complaint, negative word-of-mouth (nWOM), and inertia); 2) the moderating effect of technostress on the relationship between chatbot's communication failure and dissatisfaction; 3) the differences in the negative responses between the generation MZ and the previous generations. Data were collected via an online survey. First, the participants interacted with the chatbot developed for this survey, to experience the chatbot's communication failure. Thereafter, they responded to a questionnaire. PLS-SEM was conducted using the R software environment to test the hypotheses. This study empirically identified that chatbot's communication failure positively affected dissatisfaction. In addition, the customers who were more dissatisfied with the chatbot's communication failures were more likely to complain than engage in nWOM. Compared to the generation MZ, chatbot's communication failure caused a higher level of dissatisfaction in previous generations. The results suggest that online shopping malls should carefully introduce an improved chatbot service after minimizing its communication failure rate. The chatbot developers of online shopping malls targeting middle-aged and elderly consumers should strive to develop and implement strategies to further alleviate consumers' dissatisfaction in the situation of chatbot's communication failure.

Inhibition of collagen-induced platelet aggregation by Sanggenon N via the Ca2+ signaling pathway

  • Hyuk-Woo Kwon
    • Journal of Applied Biological Chemistry
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    • v.65 no.4
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    • pp.463-469
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    • 2022
  • Cudrania tricuspidata (C. tricuspidata), a medicinal plant widely employed throughout Asia in ethnomedicine, has various bioactive properties, including antidiabetic, antiobesity, antitumor, and anti-inflammatory activities. In addition, the C. tricuspidata root extract reportedly inhibits platelet aggregation. Therefore, we focused on the active substances present in the C. tricuspidata extract. Sanggenon N (SN) is a flavonoid found in the root bark of C. tricuspidata. In the present study, we examined the inhibitory effects of SN on platelet aggregation, phosphoproteins, thromboxane A2 generation, and integrin αIIbβ3 activity. SN inhibited collagen-induced human platelet aggregation in a dose-dependent manner without cytotoxicity. Furthermore, SN suppressed Ca2+ mobilization and influx through associated signaling molecules, such as inositol 1, 4, 5-triphosphate receptor I (Ser1756), and extracellular signal-regulated kinase. In addition, SN inhibited thromboxane A2 generation and associated signaling molecules, including cytosolic phospholipase A2 and mitogen-activated protein kinase p38. Finally, SN could inhibit integrin (αIIb/β3) activity by regulating vasodilator-stimulated phosphoprotein and Akt. Collectively, SN possesses potent antiplatelet effects and is a potential therapeutic drug candidate to prevent platelet-related thrombosis and cardiovascular disease.

Estimation of Ventilation and Generation Rates Using Nitrogen Dioxide Measurements of Indoor and Outdoor in Houses (주택 실내.외 이산화질소 측정을 이용한 환기량 및 발생량 추정)

  • Yang, Won-Ho;Im, Sung-Guk;Son, Bu-Soon
    • Journal of Environmental Science International
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    • v.17 no.10
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    • pp.1069-1073
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    • 2008
  • Indoor air quality can be affected by indoor sources, ventilation, decay and outdoor levels. Although technologies exist to measure these factors, direct measurements are often difficult. The purpose of this study was to develop an alternative method to characterize indoor environmental factors by multiple indoor and outdoor measurements. Using a mass balance model and regression analysis, penetration factor (ventilation rate divided by the sum of ventilation rate and deposition constant) and source strength factor (source strength divided by the sum of ventilation rate and deposition constant) were calculated using multiple indoor and outdoor measurements. Subsequently, the ventilation rate and $NO_2$ generation rate were estimated. Mean of ventilation rate was 1.41 ACH in houses, assuming a residential N02 deposition constant of 0.94 $hr^{-1}$. Mean generation rate of $NO_2$ was 16.5 ppbv/hr. According to house characterization, inside smoking and family number were higher $NO_2$ generation rates, and apartment was higher than single-family house. In conclusion, indoor environmental factors were effectively characterized by this method using multiple indoor and outdoor measurements.

Fault Prediction of Photovoltaic Monitoring System based on Power Generation Prediction Model (발전량 예측 모델 기반의 태양광 모니터링 시스템 고장 예측)

  • Hong, Jeseong;Park, Jihoon;Kim, Youngchul
    • Journal of Platform Technology
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    • v.6 no.2
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    • pp.19-25
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    • 2018
  • Existing Photovoltaic(PV) monitoring system monitors the current, past power generation, all values of environmental sensors. It is necessary to predict solar power generation for efficient operation and maintenance on the power plant. We propose a method for estimating the generation of PV data based PV monitoring system with data accumulation. Through this, we intend to find the failure prediction of the photovoltaic power plant in proportion to the predicted power generation. As a result, the administrator can predict the failure of the system it will be prepared in advance.

EFFECTS OF THE RECASTING ON THE PHYSICAL PROPERTIES OF Ni-Cr BASED ALLOY FOR FUSED PORCELAIN (도재소부용(陶材燒付用) Ni-Cr 합금(合金)의 재주조(再鑄造)가 물리적(物理的) 성질(性質)에 미치는 영향(影響)에 관(關)한 연구(硏究))

  • Kim, S.I.;Kim, C.C.;Park, N.S.;Han, M.H.
    • The Journal of Korean Academy of Prosthodontics
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    • v.19 no.1
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    • pp.55-60
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    • 1981
  • Some physical properties of Ni-Cr based alloy for porcelain veneering were compared after repeated casting without the addition of any new alloy. The specimen were cast in a centrifugal caster with an oxygen-propane torch at optimum temperature. The obtained results were as follows: 1. The yield strength and hardness of the second generation were no significant differences compared with first generation but the yield strength and hardness of the third generation slightly decrased. 2. The ultimate tensile strength and elongation appeared to decrease slightly in second, third generations. 3. The tensile fractured facets of the first generation specimen were normal in all specimen, but in the second generation there were six tensile specimen out of ten, in the third there were four tensile specimen out of ten.

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Next Generation Smart-City Facility Platform and Digital Chain (차세대 스마트도시 시설물의 플랫폼 정의와 디지털 체인)

  • Yang, Seung-Won;Kim, Jin-Wooung;Kim, Sung-Ah
    • Journal of KIBIM
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    • v.10 no.4
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    • pp.11-21
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    • 2020
  • With increasing interest and research on smart cities, there is also an increasing number of studies on urban facilities that can be built within smart cities. According to these studies, smart cities' urban facilities are likely to become high value-added industries. However, the concept of smart city is not clear because it involves various fields. Therefore, in this study, the definition of Next-Generation(N.G) Smart City Facilities with Digital Twin and Digital Chain is carried out through a multidisciplinary approach. Based on this, Next-Generation Smart City Facilities will be divided into High Value-Added Products and Big Data Platforms. Subsequently, the definition of the Digital Chain containing the data flow of the entire process built through the construction of the Digital Twin proceeds. The definitions derived are applied to the Next-Generation Noise Barrier Tunnel to ensure that data is exchanged at the Digital Twin stage, and to review the proposed configuration of the Digital Chain and Data Flow in this study. The platform definition and Digital Chain of Next-Generation Smart City Facilities proposed in this study suggest that it can affect not only the aspects of data management that are currently in the spotlight, but also the manufacturing industry as a whole.

Changes of Chemical Characteristics of the Industrial Wastewater Sludge in Soil (공단폐수슬러지의 토양중 화학적 특성 변화)

  • Lee, Hong-Jae;Cho, Ju-Sik;Heo, Jong-Soo
    • Journal of Environmental Science International
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    • v.5 no.4
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    • pp.525-533
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    • 1996
  • Chemical characteristics of the industrial wastewater sludge, degradation of the sludge in soil and CO2 generation and changes of nitrogen in soil treated with the sludge were investigated. The results obtained were summarized as follows: 1. Degradation rate of the sludge in soil was 26% at natural temperature, and 33% at incubation temperature at 12 weeks after treatment. 2. T-C, T-N and the C/N ratio of sludge in soil was 16.0%, 0.63% and 26, respectively, at natural temperature, and 15.0%, 0, 65% and 23, respectively, at incubation temperature at 12 weeks after treatment. 3, Camulative CO2 generation in soil treated with l%, 3% and 5% of sludge was 284, 440 and 512 mg/100 g, respectively, at natural temperature, and 440, 558 g and 654 mg/100g, respectively, at incubation temperature at 12 weeks after treatment. 4, Changes of :norganic nitrogen in soil treated with l%, 3% and 5% of sludge were 7.8, 12.8 and 16.3 mg/100g, respectively, at incubation temperature at 12 weeks after treatment. Mineralization ratio of organic nitrogen in soil treated with 1%, 3% and 5% of sludge was 10.7%, 13.6% and 15.2%, respectively, at incubation temperature at 12 weeks after treatment. 5. Chanties of pH in soil treated with 1%, 3% and 5% of Industrial wastewater sludge were in the range of 6.7~7, 5 at natural temperature, and 6.1~7.9 at incubation temperature at 12 weeks after treatment.

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DGA-DNS Similarity Analysis and APT Attack Detection Using N-gram (N-gram을 활용한 DGA-DNS 유사도 분석 및 APT 공격 탐지)

  • Kim, Donghyeon;Kim, Kangseok
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.28 no.5
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    • pp.1141-1151
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    • 2018
  • In an APT attack, the communication stage between infected hosts and C&C(Command and Control) server is the key stage for intrusion into the attack target. Attackers can control multiple infected hosts by the C&C Server and direct intrusion and exploitation. If the C&C Server is exposed at this stage, the attack will fail. Therefore, in recent years, the Domain Generation Algorithm (DGA) has replaced DNS in C&C Server with a short time interval for making detection difficult. In particular, it is very difficult to verify and detect all the newly registered DNS more than 5 million times a day. To solve these problems, this paper proposes a model to judge DGA-DNS detection by the morphological similarity analysis of normal DNS and DGA-DNS, and to determine the sign of APT attack through it, then we verify its validity.

Next-Generation File Transfer Protocol Which support concurrent file transmissions effectively in Internet (인터넷에서 동시 파일 전송을 효과적으로 지원하는 NFTP의 설계 및 구현)

  • Choi, Jae-Nam
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.27 no.1C
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    • pp.90-95
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    • 2002
  • Though the FTP(File Transfer Protocol) has been used widely and stable, It has the structural weakness that can't support current file transmissions so that we have to wait the completion of previous file transmission when try to transmit another file. If try to transmit multiple files concurrently using this FTP, It has to forking multiple FTP servers and clients in each user's PC and ISP's host machine it would result in the waist of memory, resource of network and the high workload of system. In order to solving previous problem, in this paper I have designed the new model of FTP which based on multi-thread and created NFTP(Next-Generation FTP)protocol so that may reduce the workload of system and support current file transmission effectively. I have implemented NFTP and also applied to real service, as a result It have provided reliable service by reducing the workload of system and saved the waiting time which would happened.