• Animal cells and systems
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• v.5 no.1
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• pp.25-29
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• 2001

Two new species belonging to genus Mycale are described from the waters around Geojedo Island and Gageodo Island, Korea. Mycale (M.) geojensis n. sp. seems close to M. (M.) adhaerens parvasigma Hoshino, 1981, but our new species has three categories of anisochelae. M. (Aegogropila) hentscheli n. sp. is closest to M. (A.) obscura (Carter, 1882) in shape and spicule, but has no large sigma.

• Animal Systematics, Evolution and Diversity
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• v.21 no.2
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• pp.243-250
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• 2005

A taxonomic study on the marine sponges was conducted with materials which were collected from Ulleung Island and Chuja Island, Korea by SCUBA diving during the period of July 2000 to May 2005. Among them, two species, Mycale (Aegogropila) jukdoensis n. sp. and Mycale (Mycale) chujaensis n. sp. are new to science. M. (A.) jukdoensis n. sp. seems closely to M. grandis based on the shape of spicules, but our new species has two categories of subtylostyles and also larger sigmas and raphides than those of M. grandis. And anisochelae I of M. (A.) jukdoensis n. sp. is smaller than that of M. grandis. M. (M.) chujaensis n. sp. is similar to M. sulgata in the growth form and size of microscleres. However, the new species has two categories of subtylostyles instead of one type in M. sulgata.

• Animal cells and systems
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• v.8 no.2
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• pp.71-75
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• 2004

A study on marine sponges was conducted by SCUBA diving at Ulleungdo Island, Korea, from July 2001 to August 2003. Two species, Mycale (Naviculina) ulleugensis and Mycale (N.) neunggulensis, are new to science. Mycale (N.) ulleugensis n. sp. seems close to M. chungae based on the shape of spicules, but differs in the size of megascleres and sigmas, Mycale (N.) neunggulensis n. sp. seems close to M. flagellifer Vacelet and Vasseur in the type and size of spicules, but differs in the shape of naviculichela. Naviculichela I of M. flagellifer has a spine on the upper part of the felix.

• Animal Systematics, Evolution and Diversity
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• v.35 no.4
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• pp.200-203
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• 2019

A new marine sponges, Mycale (Carmia) ieoensis n. sp., of the family Mycalidae was collected SCUBA diving in June 2017 from Ieodo Ocean Research Station, Korea. M. (C.) ieoensis n. sp. is encrusting to irregular massive type, yellow in life. This new species is similar to M. nullarosette Hoshino, 1981 in color and growth form but it differs in spicule size and sigma shape. Spicule size of M. (C.) ieoensis n. sp. smaller than that M. nullarosette. Also, M. (C.) ieoensis n. sp. has two size toxa, but M. nullarosette is not. The new species are compared to other Mycale species from the Korean region, and similar species from elsewhere.

• Proceedings of the Zoological Society Korea Conference
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• 1999.10b
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• pp.63.2-63
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• 1999

• Archives of Pharmacal Research
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• v.28 no.12
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• pp.1341-1344
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• 2005

Bioassay-guided fractionation of $CHCl_{3}$ extract from the fermentation broth of a sponge Mycale plumose-derived actinomycete Saccharopolyspora sp. nov., led to the isolation of two known prodigiosin analogs - metacycloprodigiosin (1) and undecylprodigiosin (2). These compounds exhibited significant cytotoxic activities against five cancer cell lines: P388, HL60, A-549, BEL­7402, and SPCA4. This is the first report on the significant cytotoxicity of metacycloprodigiosin (1) against human cancer cell lines.

• Proceedings of the Zoological Society Korea Conference
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• 2003.08a
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• pp.124.3-124
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• 2003

No Abstract, See Full Text

• The Korean Journal of Zoology
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• v.11 no.2
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• pp.37-47
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• 1968

During the period from July 1956 to July 1967, authors collected marine sponges from the East sea, the Korea Strait and the Yellow sea. The results of the identification turned out to be 17 species, 14 genera and 10 families. The species are as follows: Family Haliclonidae: 1. Haliclona permollis; Family Callyspongiidae: 2. Callyspongia elegans, 3. C. ramosa, 4. Ceraochalina differentiata; Family halichondriidae: 5. Halichondria japonica, 6. H. okadai, 7. H. oshoro, 8. H. panicea; Family Suberitidae: 9. Suberites ficus; Family Myxillidae: 10. Myxilla setoensis, 11. Lissodendoryx isodictyalis; Family Ophlitaspondiidae: 12. Ophlitaspongia noto, 13. Mycale plumosa; Family Ancorinidae: 14. Penares incrustans; Family Tethyidae: 15. Tethya japonica; Family Grantiidae: 16. Leucandra tuba; Family Heteropiidae: 17. Vosmaeropsis japonica.

• Toxicological Research
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• v.17
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• pp.105-108
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• 2001

Several marine toxins with macrolide structure have been found to act on actin. One of these toxins is mycalolide B isolated from the genus Mycale. This compound belongs to macrolide antibiotics and consists of tris-oxazole with strong cytotoxic activity ($IC_{50}$: 10-50 nM for growth of L1210 murine leukemia cells). This compound was found to be an actin-depolymerizing agent with the mode of action distinct from that of the known actin inhibitor, cytochalasin D. Tolytoxin, a macrolide isolated from cyano-bacteria with similar chemical structure to mycalolide B, seems to have similar effect. Another macrolide compound, aplyronine A, showed the effects similar to those of mycalolide B. Although bistheonellide A, a dimeric macrolide, did not show a severing effect, it de polymerized F-actin and sequestered G-actin by forming 1 : 2 complex with G-actins. Swinholide A has a structure and effects similar to those of bistheonel-lide A. In conclusion, mycalolide B, tolytoxin, aplyronine A, bistheonellide A and swinholide A are the members of "actin de polymerizing macrolide" the mechanism of which is different from that of cytochalasin D.halasin D.