• 한국융합학회논문지
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• 제11권6호
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• pp.215-225
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• 2020

본 연구는 정부 기관에서 제시하는 청소년 신체활동지침의 실천과 스마트폰으로 인한 문제경험과의 관계를 파악하고자 한다. 이를 위해 62,225명의 "2017년 청소년건강행태조사" 데이터를 활용하여 신체활동지침의 실천과 스마트폰 변인간의 관계를 분석하였으며, SPSS 23.0 프로그램을 이용하여 다중회귀분석을 실시하였다. 분석결과 "60분이상 신체활동"을 제외한 모든 신체활동이 스마트폰으로 인한 문제경험에 부(-)적 영향을 미치는 것으로 나타났다. 또한, 유산소운동, 근력운동, 스포츠클럽참여, 좌식행동 등 정부 기관에서 제시하는 신체활동지침을 실천하는 학생은 미실천학생에 비해 스마트폰 문제경험이 감소하였으며 이는 성별로 유의한 차이를 보였다. 본 결과에 따라, 스마트폰 중독예방에 있어 해당 지침을 활용한 학술적인 심층연구와 성별로 차별화된 신체활동 증진 프로그램이 가능할 것으로 기대한다.

• 운동영양학회지
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• 제23권4호
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• pp.36-42
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• 2019

[Purpose] The study aimed to determine the effects of bone-specific physical activity on body composition, bone mineral density (BMD), and health-related physical fitness in middle-aged women. [Methods] One hundred eighty-six middle-aged women aged 31-49 years participated in this study. The subjects were divided into tertile groups according to the level of physical activity (low-score group, n=62; middle-score group, n=62; high-score group, n=62). Bone-specific physical activity participation was assessed using the bone-specific physical activity questionnaire. Body composition and BMD were measured using dual-energy X-ray absorptiometry. Health-related physical fitness test included isometric muscle strength (grip strength), muscular endurance (sit-ups), flexibility (sit and reach), and cardiorespiratory fitness (maximal oxygen uptake [VO_2max]). [Results] The high-score group had a significantly higher fat-free mass (p=.045, partial eta-squared value[η_p²]=.033) than the middle- and low-score groups, whereas the high-score group had significantly lower percent body fat (p=.005, η_p²=.056) than the other two groups. Whole-body BMD (p=.034, η_p²=.036) and lumbar BMD (p=.003, η_p²=.060) were significantly higher in the high-score group than in the low-score group. The high-score group performed significantly better for grip strength (p=.0001, η_p²=.101), sit-ups (p=.0001, η_p²=.108), and VO_2max (p=.0001, η_p²=.092) than the other two groups. [Conclusion] The present study suggests that bone-specific physical activity could be useful in improving body composition, BMD, and health-related physical fitness in middle-aged women, significantly enhancing their BMD and health conditions.

• 생명과학회지
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• 제27권10호
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• pp.1207-1214
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• 2017

노화에 따른 퇴행성관절염은 삶의 질을 저하시키는 가장 큰 병리학적 현상 중의 하나이다. 오미자 열매(Schisandrae Fructus)는 오랫동안 전통의학에서 여러 가지 만성질환 치료를 위해 널리 사용되어 왔다. 오미자 추출물이 SW1353 인간 연골세포에서 $IL-1{\beta}$에 의해 유발된 염증 반응을 감소시키는 것으로 최근 보고된 바 있으나, primary culture된 연골세포 및 동물 모델에서의 퇴행성관절염에 대한 보호 및 치료 잠재력은 여전히 명확하지 않다. 따라서 본 연구에서는 $IL-1{\beta}$에 의해 유도된 primary culture된 쥐의 연골세포와 MIA에 의해 유도된 골관절염에 대한 matrix metalloproteinases (MMPs)의 활성에 미치는 오미자 에탄올 추출물의 영향을 조사하였다. 오미자 추출물 처리는 $IL-1{\beta}$로 유도된 연골세포에서 MMP-1, -3 및 -13의 mRNA 발현 및 효소 활성을 유의하게 감소시켰다. 또한 오미자 추출물은 MIA에 의해 증가된 MMP-1 및 -3의 발현을 유의적으로 억제시켰다. 따라서 오미자 추출물은 퇴행성관절염 예방과 치료를 위한 기능성 소재로서의 잠재적 가능성이 있음을 알 수 있었다.

• 한국어병학회지
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• 제21권1호
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• pp.45-56
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• 2008

This study was conducted to find out biological responses of bivalves exposed to organotin compound.The results of the study confirmed that tribultyltin chloride (TBTCl) induce reduction of survival rate andburrowing activity, and histopathological feature in the foot structure of the equilateral venus, Gomphinaveneriformis. The experimental period was 36 weeks. The experimental groups consisted of a control and 3TBTCl exposure groups (0.4, 0.6, 0.8 ym TBTCl L'). The survival rate and burrowing activity were record-ed daily. For histological analysis, foot tissues were fixed in Bouin' s fluid and then stained H-E stain, AB-PAS (PH 2.5) reaction and Masson's trichrome stain after having serially sectioned the tissue by paraffinmethod at thickness of 4-6 ym. The survival rate was not significantly different between the control andexposure groups for 20 weeks, but in 0.8 Um TBTCl L', it was on the decreased ever since the exposure. Theburrowing activity was not significantly different in the exposure group compared to the control up to 12weeks, but in 0.6 and 0.8 ym TBTCl L', it measured the lowest level after 20 weeks. The foot is composedof the epidermal layer, connective tissue, and muscular layer. The epidermal layer is composed of simplecolumnar, cuboidal epithelia and mucous cells. The cilia were well developed on the apical surface ofepithelium, Circular, longitudinal and transverse muscle bundle were well developed in the muscular layer.The majority mucous cells showed blue color (542c) when it subjected to AB-PAS (PH 2.5) reaction. Nohistopathological alterations in the foot were observed up to 12 weeks. After 20 weeks of exposure to 0.8 (anTBTCl L'', the foot samples of exposed G. veneriformis showed disappearance of cilia and striated borderpartially and extension of hemolymph sinus. The mucous cell increased in the marginal of foot. At 28-weekof exposure to 0.4 ym TBTCl L', it observed weekly acid (564c), neutral (264c) and mixed mucous cell. At36-week of exposure to 0.6 ym TBTCl L', it showed fragmentation of the muscle and collagen fiber bundle,and also diappearance of cilia on epithelia and edema of epithelium in 0.8 ym TBTCl L''.

• 대한물리치료과학회지
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• 제21권1호
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• pp.79-84
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• 2014

Background : This study is for respiratory muscle activity and chest expansion through practice abdominal breathing exercises. Methods : The subjects were consisted normal 30 persons(15 males and 15 females). The control group to 15 people to compare group and 15 people for the abdominal breathing exercise group through lip retraction movement of the therapist with the resistance of mediated abdominal breathing exercises. For 8 weeks EMG was used to know the changes in respiratory muscle. We also found out the changes in chest expansion. And the t-test was conducted to analyze among the compared group, the abdominal breathing group the differences between before and after the experiment. Results : On the changes in respiratory muscle muscular activity in the transverse abdominis have shown significant results(p<.05), and the change in chest expansion was no significant(p>.05). Conclusion : Various breathing exercises in future research on intervention programs can be studied to promote the public if the functional status is considered to be of much help.

• Archives of Pharmacal Research
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• 제25권4호
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• pp.493-499
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• 2002

We investigated the antitumor activity of oregonin, a diarylheptanoid derivative purified from Alnus hirsuta Turcz, Betulaceae. Oregonin is a potential novel immunomodulator, which augments the activation of natural killer (NK) cells, and thereby leads to a powerful antitumor activity. To evaluate the cytotoxicity of oregonin against tumor cells, we examined the effectiveness of NK cells and determined that oregonin could increase NK cell cytotoxicity. This was confirmed by MTT assay. In addition, the survival time of C57BL/6 mice were measured by inoculating 816-F10 melanoma cells to mice via intra muscular (i.m.) injection. Oregonin treatment after 10 hours of inoculation at 10 mg/kg dosage showed a significant extension of survival time by up to 51.32%, when compared to the control group. Moreover, oregonin significantly reduced the incidence of pulmonary metastasis, which may be developed from 816-F10 melanoma cells. These findings suggest that oregon in may be classified as a new and novel immunomodulator due to its potential antitumor activity.

• PNF and Movement
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• 제22권1호
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• pp.151-158
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• 2024

Purpose: The present study investigated how variations in diagonal exercises affect shoulder muscle activity, examining changes in neuromuscular activation during scapular and shoulder diagonal patterns of exercises. Furthermore, we explored whether the exercise phase affects muscle activation. Methods: Sixteen asymptomatic male participants were recruited. Four diagonal pattern exercises (scapular anterior elevation, posterior elevation, flexion-adduction-external rotation, flexion, abduction-external rotation), and two exercise phases (concentric and eccentric) were administered. Surface electromyography data were collected. Results: Upper trapezius activity was significantly higher during the concentric phase of scapular posterior elevation exercises compared with the others (p<0.05). The serratus anterior, anterior deltoid, and infraspinatus activities were significantly higher during shoulder diagonal pattern exercises compared with the scapular diagonal pattern exercises (p<0.05). Except for the lower trapezius, muscular activities during the concentric phase were significantly greater compared with the eccentric phase (p<0.05). Conclusion: The current study suggests that the diagonal pattern of exercise may contribute to selective strengthening of the shoulder complex muscles and that the form of exercise should be tailored to the subject. It also suggests that diagonal exercises with concentric contractions tend to be more beneficial than eccentric contractions for overall muscle recruitment, but the effects vary for specific diagonal patterns.

• Journal of Preventive Medicine and Public Health
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• 제7권1호
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• pp.115-121
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• 1974

In order to evaluate the health hazard due to exposure to organophosphorus insecticides, we measured the blood cholinesterase activity ana urinary para-nitrophenol among 56 exposed subjects. They are orchard workers, rice plant workers and smithion factory workers. The clinical symptoms were also checked by physicians. We also measured the blood cholinesterase activity and urinary para-nitrophenol excretion of 20 urban people and 15 rural people who had never been exposed to organophosphorus insecticides in order to compare them according to age, sex and geographical differences. And these results were also compared with those of exposed groups. The results obtained were as follows. 1. The normal plasma cholinesterase activity and cell cholinestrase activity were $0.861{\pm}0.148\;{\Delta}pH/hr$ and $0.822{\pm}0.154\;{\Delta}pH/hr$. And normal para-nitrophenol in urine was $1.21{\pm}0.52mg/liter$. 2. No significant difference was existed in blood cholinesterase activities and urinary para-nitrophenol excre tion according to sex, age and geographical difference. 3. The plasma cholinesterase activity and cell cholinesterase activity of orchard workers, rice plant workers and smithion factory workers were $0.682{\pm}0.189\;{\Delta}pH/hr,\;0.775{\pm}0.160\;{\Delta}pH/hr,\;0.754{\pm}0.123\;{\Delta}pH/hr,\;and\;0.691{\pm}0.082\;{\Delta}pH/hr,\;0.756{\pm}0.117\;{\Delta}pH/hr,\;0.739{\pm}0.117\;{\Delta}pH/hr$. And significant decreses in blood cholinesterase activities were existed among orchard workers and smithion factory workers compared with control group. 4, The urinary para-nitrophenol excretions of orchard workers, rice plant workers and smithion factory workers were $1.33{\pm}0.66mg/liter,\;1.19{\pm}0.88mg/liter\;and\;1.37{\pm}0.67mg/liter$ and there were no significant difference between exposed groups and control group. 5. The clinical symptoms complained during and after organophosphorus insecticides exposure were frequently ranked by headache (67.7%) and vertigo (64.5%) and muscular ataxia and weakness (51.6%).

• 대한통합의학회지
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• 제3권1호
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• pp.81-90
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• 2015

Purpose: The purpose of this study was to investigate any visible difference in shoulder stability muscle activity along the bending angle($70^{\circ}$, $90^{\circ}$, $110^{\circ}$) to perform the open kinetic chain(OKC) and closed kinetic chain(CKC) exercise. Method: This study was performed on normal 20 males subjects. Exercise was carried out in two ways OKC and CKC. Shoulder stability muscles are examined activity in the bending angles. In the OKC and CKC exercise to subjects with stretched out waist straightened, and than push forward the shoulder. Muscular activation was examined using the WEMG-8. Result: The results of this study were as follows. 1. Only in the trapezius muscle, it showed specific interaction between exercise methods and angles. When it comes to muscle activity, there was no significant difference in all muscles except for the anterior fibers of the deltoid muscle during both CKC and OKC exercise. 2. The average value of maximum muscle activity was significantly increased with increasing order of angles. But in CKC exercise, the muscle activity of infraspinatus tended to decrease with increasing angles. Conclusion: To summarize the research results, the muscle activity in upper fibers of the trapezius, anterior fibers of the deltoid, and serratus anterior was significantly different depending on the angle of the shoulder in both CKC and OKC exercise.

• 대한통합의학회지
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• 제7권4호
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• pp.291-300
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• 2019

Purpose : This study focuses on the influence of bridge exercise combined with whole body vibration on muscle activity and balance. Methods : 30 stroke patients were recruited for subjects. The subjects were divided to bridge exercise combined stable surface (Group I), bridge exercise combined unstable surface (Group II), and bridge exercise combined bridge exercise (Group III), of which 10 subjects were randomly allocated. The subjects were given 30 minutes of neurologic physical therapy which included gait training and muscular strength training, and additionally given 30 minutes of bridge exercise combined stable surface, bridge exercise combined unstable surface, and bridge exercise combined whole body vibration for each group, five times a week, for 8 weeks. Their muscle activity and balance were analyzed before the intervention. After 8 weeks of the intervention, the mentioned parameters were measured once more for between-group analysis. Results : Comparative analysis of the muscle activity and balance between the groups showed statistically significant difference, and post-hoc analysis showed the Group III had greater changes in muscle activity and balance than Group Iand Group II. Conclusion : Such results revealed that bridge exercise combined with whole body vibration is effective in muscle activity and balance. Based on the current study, more effective program is to be proposed for elite athletes as well as stroke patients. Based on the current study, studies that incorporates various frequencies of vibration is required for development of effective whole body vibration exercise program.