• 제목/요약/키워드: Muscle pathology

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전염성근괴사증바이러스(IMNV)를 인위감염 시킨 흰다리새우(Litopenaeus vannamei)의 근육에서 나타난 미세 손상과 염증반응에 대한 조직병리학적 특성 연구 (Histopathological features of pacific whiteleg shrimp, Litopenaeus vannamei, infected with Infectious Myonecrosis Virus (IMNV) with an emphasis on micro-traumas and inflammatory responses in muscle tissues)

  • 이효은;김영숙;장진현;천원주;최가영;;김수미
    • 한국어병학회지
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    • 제35권2호
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    • pp.167-176
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    • 2022
  • We injected infectious myonecrosis virus (IMNV) to pacific whiteleg shrimp, Litopenaeus vannamei, and observed closely with using light microscope and transmission electron microscope (TEM) for 4-8 days post infection (dpi). As clinical signs, abdominal bodies had mild opaque muscles at 5 dpi. And the mortality was shown at 6 dpi. At 8 dpi, most injected shrimps had severe opaque muscles and humped back that cause of movement disorder. As results of histopathological examinations, local parts of abdominal body muscle had muscle fiber hyalinization, muscle fiber atrophy, rounded muscle fibers, myofibrillar hypertrophy in size, a decrease in number of myofibrils and phagocytosis from the sarcolemmas by multiple hemocytes at 4 dpi. Especially, myofibrillar hypertrophy appeared at the whole or random part of single muscle fiber not in specific locations like the center or edge of muscle fiber. At 6-7 dpi, multiple muscle necrosis, muscle fiber segmentation, myofibril lysis ap- peared and a few hemocytes were infiltrated at lesions. At 8 dpi, extensive muscle necrosis, multiple myofibril lysis and muscle fiber atrophy were shown, and very few hemocytes were infiltrated. In early stage of infection, local viral myositis with zenker's degeneration were shown. These lesions appeared multiply after the early stage. In late stage of infection, extensive coagulative muscle necrosis appeared with few of inflammatory response such as hemocytes infiltration. The lack of hemocytes infiltration response at the late stage might be disadvantage for Litopenaeus vannamei to defense against IMNV and to recover, because hematocytes (granulocyte, semi-granulocyte) eliminate pathogen and damaged tissues from infection sites and help recover. As results of the TEM observation, IMNVs that had nonenveloped icosahedral capsid which was 30-40 nm diameter were in myofibril and beside tubules of sarcoplasmic reticulum and moved to the certain direction. The micro-tears and micro-trau- mas in myofibrils caused muscle fiber necrosis. And semi-granulocytes engulfed IMNVs to eliminate virus.

Body Mass Index(BMI) 분류에 따른 그룹들 간 근육둘레비율의 상관성 연구 (Study on Muscle Circumference Among Groups Divided by Body Mass Index(BMI))

  • 김동건;차윤엽;박원형
    • 동의생리병리학회지
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    • 제19권4호
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    • pp.1099-1103
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    • 2005
  • This study aims to confirm the importance of behavior habit and exercise, especially leg exercise in obese. Out of 889 people, We divided Group A 50 (BMI<18.5), Group B 210 $(18.5{\leq}BMl<23)$, Group C 202 $(23{\leq}BMI<25)$, Group D212 $(25{\leq}BMI<30)$ and Group 1215 (30

체간 조절을 통한 앉기 자세 교정이 경직형 뇌성마비 아동들의 호흡근과 음향학적 측정치들의 변화에 미치는 효과 (The Effects of Changing the Respiratory Muscles and Acoustic Parameters on the Children With Spastic Cerebral Palsy)

  • 김선희;안종복;서혜정;권도하
    • 한국전문물리치료학회지
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    • 제16권2호
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    • pp.16-23
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    • 2009
  • The purpose of this study was to investigate the effects postural changes on respiratory muscles and acoustic parameters of the children with spastic cerebral palsy. Nine children with spastic cerebral palsy who required assistance when walking were selected. The ages of the children ranged from 6 to 9 years old. The phonation of the sustained vowel /a/ and the voice qualities of each child such as fundamental frequency($F_0$; Hz), pitch variation (Jitter; %), amplitude variation (Shimmer; %) and noise to harmonic ratio (NHR) were analyzed by Multi-Dimensional Voice Program (MDVP). The muscle activity of three major respiratory muscles: pectoralis major muscle, upper trapezius muscle and rectus abdorminalis muscle, were measured by examining the root mean square (RMS) of the surface EMG to investigate the impact of changes in the adjusted sitting posture of each subject. However, the RMS of pectoralis major muscle showed a significant differences (p<.05). Secondly, there were no significant differences in $F_0$, Jitter and Shimmer between pre and post posture change, but there was a significant difference in NHR (p<.05). The data were collected in each individual; once prior and once after the sitting posture change. The data were analyzed by Wilcoxon signed ranks-test using SPSS version 14.0 for Windows. The findings of this study were as follows; Firstly, the RMS of upper trapezius and rectus abdorminalis muscle were not significant different between pre and post sitting posture changes. From the result, it is concluded that changes in the adjusted sitting posture decreases the abnormal respiratory patterns in the children with spastic cerebral palsy which is characterized by the hyperactivity of the respiratory muscles in breathing. Also, there is increased on the voice qualities in children with spastic cerebral palsy.

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Intramuscular hemangiomas on the masseter muscle and orbicularis oris muscle: a report of two cases

  • Kim, Il-Kyu;Seo, Ji-Hoon;Cho, Hyun-Young;Lee, Dong-Hwan;Jang, Jun-Min;Kim, Joon Mee;Park, In Suh
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제43권2호
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    • pp.125-133
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    • 2017
  • Intramuscular hemangioma (IMH) is a rare vascular disease involving skeletal muscle, comprising only 0.8% of hemangiomas. About 10% to 15% of IMHs occur in the head and neck region, mostly involving the masseter muscle. IMH occurs mostly in childhood, but is often not found until unexpected enlargement, pain, or cosmetic asymmetry occurs in adulthood. Several non-surgical treatments including cryotherapy, sclerosant injection, and arterial ligature have been described, but complete surgical resection is the curative intervention. In this report, we present two rare cases of IMH. One IMH case in a 48-year-old male occurred in the masseter muscle feeding from the transverse facial artery. Embolization of the distal branch of the facial artery was first conducted, and then the buccal mass was removed surgically via the intraoral approach. A second IMH case in a 58-year-old female occurred in the orbicularis oris muscle feeding from the superior labial artery, and the mass was excised surgically without embolization.

멍게 물렁증 근육변성의 병인에 관한 연구 (Histopathological studies on the degenerative changes of somatic muscle in soft tunic syndrome of ascidian, Halocynthia roretzi)

  • 허민도;이효은;이무근;김보성
    • 한국어병학회지
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    • 제34권1호
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    • pp.63-70
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    • 2021
  • As a part of research to elucidate the pathogenesis of so called Soft Tunic Syndrome(STS), that caused mass mortalities in the cultured sea squirts, Halocynthia roretzi, the epidemiological and pathological analysis were done to both clinically normal and diseased groups of the farms of Tongyoung and Geoje coastal areas in southeast sea from February to July, 2008. In the histological finding of the tunic, most of individuals showed tunic softness syndromes that included the disarrangement and destruction of tunic fiber with the simultaneous presence of flagellates-like cells, recently suspected as main agents of tunic softness syndromes. Simultaneously, the intensive degenerative changes of the skeletal muscle of diseased sea squirts were recognized. The changes were characterized with the hyalinization and condensation of muscle fibril and hemocytic infiltration in the muscle fibers. Those were thought to be a kind of typical Zenker's necrosis as in the skeletal muscle of higher vertebrates. Besides of the diseased sea squirts, Zenker's necrosis of skeletal muscles were seen in the normal ones. Epidemiological inquiry for diseased groups revealed that the higher incidences of tunic softness syndrome were recorded in the fast growing groups and in the sites presuming the organic pollution. And Higher malondialadehyde(MDA) and glutathione peroxidase(GPx) activity were detected in the groups showing STS. Those results suggested that Zenker's necrosis of body muscles was a kind of"nutritional myopathy" by oxidative stress. Conclusively, it was considered that Zenker's necrosis of body muscles gives an important clue for elucidating pathogenesis of STS of cultured squirts. And it seems that the necrosis were caused by the oxidative stress to body muscle during abnormal rapid growth of sea squirts.

A hemangioma in the masseter muscle: a case report

  • Park, Daehwan;Park, Sulki;Baik, Bongsoo;Kim, Sunyoung
    • 대한두개안면성형외과학회지
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    • 제22권4호
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    • pp.218-221
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    • 2021
  • Intramuscular hemangiomas of the masseter muscle are uncommon tumors and therefore can be difficult to accurately diagnose preoperatively, due to the unfamiliar presentation and deep location in the lateral face. A case of intramuscular hemangioma of the masseter muscle in a 66-year-old woman is presented. Doppler ultrasonography showed a 34×15 mm hypoechoic and hypervascular soft tissue mass in the left masseter muscle, suggesting hemangioma. The mass was excised via a lateral cervical incision near the posterior border of the mandibular ramus. The surgical wound healed well without complications.

Concomitant variations of the tibialis anterior, and extensor hallucis longus, and extensor hallucis brevis muscles

  • Jenilkumar Patel;Graham Dupont;Joho Katsuta;Joe Iwanaga;Lukasz Olewnik;R. Shane Tubbs
    • Anatomy and Cell Biology
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    • 제56권1호
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    • pp.137-140
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    • 2023
  • Tibialis anterior (TA) muscle originates from the lateral surface of tibia and its tendon attaches to the medial cuneiform and base of the first metatarsal. The TA muscle is responsible for both dorsiflexion and inversion of the foot. We present a case of bilateral TA muscle variations that diverge slightly from the current classification systems of this muscle. Recognizing variations such as these may be important for anatomists, surgeons, podiatrists, and physicians. Following routine dissection, an accessory tendon of the TA muscle was found on both sides. Accessory tendons of the extensor hallucis longus and extensor hallucis brevis joined to form a common tendon on both sides. We believe that this unique case will help further the classification systems for the tendons of the TA and also be informative for clinical anatomists as well as physicians treating patients with pathology in this region.

대흉근에서 발생한 과립 세포 종양: 유방촬영술에서 보이는 드문 유방외 병변 (Granular Cell Tumor Originating from the Pectoral Muscle: A Rare Extramammary Finding on Mammography)

  • 유현규;송성은;이정현;조규란
    • 대한영상의학회지
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    • 제83권5호
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    • pp.1195-1200
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    • 2022
  • 과립 세포 종양은 드문 연조직 종양으로써 주로 혀의 줄무늬 근육에서 발생한다. 과립 세포 종양이 대흉근에서 발생한 예는 매우 드물게 보고되었다. 이에 저자들은 유방 아래의 대흉근에 발생한 과립 세포 종양의 증례를 다양한 영상 소견과 함께 보고하고자 한다.

한국산 연어의 아니사키스형 유충의 감염현황 (Prevalence of Anisakid larvae in chum salmon Oncorhynchus keta in Korea)

  • 서정수;전은지;정승희;김명석;박명애;이철호;한명철;김진우;지보영
    • 한국어병학회지
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    • 제23권1호
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    • pp.123-129
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    • 2010
  • 2006년부터 2008년까지 국내로 회귀하는 연어(O. keta)의 소상위치, 암수 및 근육 부위별 아니사키스형 유충의 감염상을 조사하였다. 3년 동안강에서 채집된 연어 17마리와 바다에서 채집된 13마리의 아니사키스형 유충의 감염율을 조사한 결과, 강에서 채집된 연어의 수컷 및 암컷은 마리 당 아니사키스형 유충이 각각 평균 $98{\pm}27$$103{\pm}27$ 마리씩 감염되어져 있었다. 바다에서 채집된 연어의 수컷 및 암컷은 마리 당 아니사키스형 유충이 각각 평균 $63{\pm}18$$108{\pm}17$ 마리씩 감염되어져 있었고, 암수 및 소상위치간의 아니사키스형 유충의 감염 마리수에서 통계학적 차이는 없는 것으로 나타났다. 아니사키스형 유충의 근육 부위별로 조사하면 복강내측근육 (abdominal muscle)에 85%가 기생하며, 내장기관에는 거의 유충이 발견되지 않았다. 동정된 아니사키스형 유충은 Anisakis type이 74%며, 나머지는 Contracacecum type로 분류되었다. 연어 근육내에서 아니사키스형 유충의 저온처리에 따른 생존율을 조사하였을시에 최소 6시간 이상의 냉동보존 ($-20^{\circ}C$)만이 아니사키스형 유충이 죽는다는 사실을 알 수 있었다.