• Journal of the Korean Magnetic Resonance Society
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• v.22 no.3
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• pp.46-53
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• 2018

NMR-based metabolomics needs various knowledge to elucidate metabolic perturbation such as NMR experiments, NMR spectrum processing, raw data processing, metabolite identification, statistical analysis, and metabolic pathway analysis regarding technical aspects. Among them, some concepts of raw data processing and multivariate analysis are not easy to understand but are important to correctly interpret metabolic profile. This article introduces NMR spectrum processing, raw data processing, and multivariate analysis.

• Journal of the Korean Data and Information Science Society
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• v.15 no.2
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• pp.297-306
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• 2004

It is usual that multivariate data analysis produces related (small number of) artificial variates for data reduction. Among them, refer to MDS(multidimensional scaling), MDPREF(multidimensional preference analysis), CDA(canonical discriminant analysis), CCA(canonical correlation analysis) and FA(factor analysis). Varimax rotation of artificial variables which is originally invented in FA for easy interpretations is applied to diverse multivariate techniques mentioned above. Real data analysisis is performed in order to manifest that rotation improves interpretations of artificial variables.

• Proceedings of the Korea Water Resources Association Conference
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• 2008.05a
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• pp.694-698
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• 2008

In hydrology, it is a difficult task to deal with multivariate time series such as modeling streamflows of an entire complex river system. Normal distribution based model such as MARMA (Multivariate Autorgressive Moving average) has been a major approach for modeling the multivariate time series. There are some limitations for the normal based models. One of them might be the unfavorable data-transformation forcing that the data follow the normal distribution. Furthermore, the high dimension multivariate model requires the very large parameter matrix. As an alternative, one might be decomposing the multivariate data into independent components and modeling it individually. In 1985, Lins used Principal Component Analysis (PCA). The five scores, the decomposed data from the original data, were taken and were formulated individually. The one of the five scores were modeled with AR-2 while the others are modeled with AR-1 model. From the time series analysis using the scores of the five components, he noted "principal component time series might provide a relatively simple and meaningful alternative to conventional large MARMA models". This study is inspired from the researcher's quote to develop a multivariate simulation model. The multivariate simulation model is suggested here using Principal Component Analysis (PCA) and Independent Component Analysis (ICA). Three modeling step is applied for simulation. (1) PCA is used to decompose the correlated multivariate data into the uncorrelated data while ICA decomposes the data into independent components. Here, the autocorrelation structure of the decomposed data is still dominant, which is inherited from the data of the original domain. (2) Each component is resampled by block bootstrapping or K-nearest neighbor. (3) The resampled components bring back to original domain. From using the suggested approach one might expect that a) the simulated data are different with the historical data, b) no data transformation is required (in case of ICA), c) a complex system can be decomposed into independent component and modeled individually. The model with PCA and ICA are compared with the various statistics such as the basic statistics (mean, standard deviation, skewness, autocorrelation), and reservoir-related statistics, kernel density estimate.

• Journal of the Korean Statistical Society
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• v.26 no.3
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• pp.319-332
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• 1997

The application of multivariate linear rank statistics to data with item nonresponse is considered. Only a modest extension of the complete data techniques is required when the missing data may be thought of as a random sample, and an appropriate modification of the covariances is derived. A proof of the asymptotic multivariate normality is given. A review of some related results in the literature is presented and applications including longitudinal and repeated measures designs are discussed.

• Journal of the Korean Operations Research and Management Science Society
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• v.39 no.4
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• pp.51-69
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• 2014

Times to multiple events (TMEs) are a major data type in large-scale business and medical data. Despite its importance, the analysis of TME data has not been well studied because of the analysis difficulty from censoring of observation. To address this difficulty, we have developed a Bayesian-based multivariate survival analysis method, which can successfully estimate the joint probability density of survival times. In this work, we extended this method for the analysis of precedence, dependency and causality among multiple events. We applied this method to the electronic health records of 2,111 patients in a children's hospital in the US and the proposed analysis successfully shows the relation between times to two types of hospital visits for different medical issues. The overall result implies the usefulness of the multivariate survival analysis method in large-scale big data in a variety of areas including marketing, human resources, and e-commerce. Lastly, we suggest our future research directions based multivariate survival analysis method.

• Journal of Korea Multimedia Society
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• v.17 no.7
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• pp.858-865
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• 2014

In the case of system like MES, various sensors collect the data in real time and save it as a big data to monitor the process. However, if there is big data mining in distributed computing system, whole processing process can be improved. In this paper, system to analyze the cause of operation deviation was built using the big data which has been collected from deasphalting process at the two different plants. By applying multivariate statistical analysis to the big data which has been collected through MES(Manufacturing Execution System), main cause of operation deviation was analyzed. We present the example of analyzing the operation deviation of deasphalting process using the big data which collected from MES by using multivariate statistics analysis method. As a result of regression analysis of the forward stepwise method, regression equation has been found which can explain 52% increase of performance compare to existing model. Through this suggested method, the existing petrochemical process can be replaced which is manual analysis method and has the risk of being subjective according to the tester. The new method can provide the objective analysis method based on numbers and statistic.

• The Korean Journal of Applied Statistics
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• v.25 no.4
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• pp.605-612
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• 2012

Multivariate data are often generated with multiple outcomes in various fields. Multiple outcomes could be mixed as continuous and discrete. Because of their complexity, the data are often dealt with by separately applying regression analysis to each outcome even though they are associated the each other. This univariate approach results in the low efficiency of estimates for parameters. We study the efficiency gains of the multivariate approaches relative to the univariate approach with the mixed data that include continuous and binary outcomes. All approaches yield consistent estimates for parameters with complete data. By jointly estimating parameters using multivariate methods, it is generally possible to obtain more accurate estimates for parameters than by a univariate approach. The association between continuous and binary outcomes creates a gap in efficiency between multivariate and univariate approaches. We provide a guidance to analyze the mixed data.

• Communications for Statistical Applications and Methods
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• v.31 no.2
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• pp.191-202
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• 2024

The goal of this paper is to show how multivariate regression analysis with high-dimensional responses is facilitated by the response dimension reduction. Multivariate regression, characterized by multi-dimensional response variables, is increasingly prevalent across diverse fields such as repeated measures, longitudinal studies, and functional data analysis. One of the key challenges in analyzing such data is managing the response dimensions, which can complicate the analysis due to an exponential increase in the number of parameters. Although response dimension reduction methods are developed, there is no practically useful illustration for various types of data such as so-called large p-small n data. This paper aims to fill this gap by showcasing how response dimension reduction can enhance the analysis of high-dimensional response data, thereby providing significant assistance to statistical practitioners and contributing to advancements in multiple scientific domains.

• Journal of the Korean Data and Information Science Society
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• v.17 no.4
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• pp.1181-1190
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• 2006

Statistical analyses for spatial data are important features for various types of fields. Spatial data are taken at specific locations or within specific regions and their relative positions are recorded. Lattice data are synoptic observation covering an entire spatial region, like cancer rates corresponding to each county in a state. Until now, the echelon analysis has been applied only to univariate spatial data. As a result, it is impossible to detect the hotspots on the multivariate spatial data In this paper, we expand the spatial data to time series structure. And then we analyze them on the time space and detect the hotspots. Echelon dendrogram has been made by piling up each multivariate spatial data to bring time spatial data. We perform the structural analysis of temporal spatial data.

• Communications for Statistical Applications and Methods
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• v.30 no.4
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• pp.389-402
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• 2023

Multivariate or clustered failure time data often occur in many medical, epidemiological, and socio-economic studies when survival data are collected from several research centers. If the data are periodically observed as in a longitudinal study, survival times are often subject to various types of interval-censoring, creating multivariate interval-censored data. Then, the event times of interest may be correlated among individuals who come from the same cluster. In this article, we propose a unified linear regression method for analyzing multivariate interval-censored data. We consider a semiparametric multivariate accelerated failure time model as a statistical analysis tool and develop a generalized Buckley-James method to make inferences by imputing interval-censored observations with their conditional mean values. Since the study population consists of several heterogeneous clusters, where the subjects in the same cluster may be related, we propose a generalized estimating equations approach to accommodate potential dependence in clusters. Our simulation results confirm that the proposed estimator is robust to misspecification of working covariance matrix and statistical efficiency can increase when the working covariance structure is close to the truth. The proposed method is applied to the dataset from a diabetic retinopathy study.