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The Iron Status of Very Low Birth Weight Infants Receiving Multiple Erythrocyte Transfusions during Hospitalization in the Neonatal Intensive Care Unit

  • Park, Sook-Hyun;Kim, Heng-Mi
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제18권2호
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    • pp.100-107
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    • 2015
  • Purpose: We investigated the iron status of very low birth weight infants receiving multiple erythrocyte transfusions during hospitalization in the neonatal intensive care unit (NICU). Methods: We enrolled 46 very low birth weight infants who were admitted to the Kyungpook National University Hospital between January 2012 and December 2013. Serum ferritin was measured on their first day of life and weekly thereafter. We collected individual data of the frequency and volume of erythrocyte transfusion and the amount of iron intake. Results: A total of 38 (82.6%) of very low birth weight infants received a mean volume of $99.3{\pm}93.5mL$ of erythrocyte transfusions in NICU. The minimum and maximum serum ferritin levels during hospitalization were $146.2{\pm}114.9ng/mL$ and $456.7{\pm}361.9ng/mL$, respectively. The total volume of erythrocyte transfusion was not correlated to maximum serum ferritin concentrations after controlling for the amount of iron intake (r=0.012, p=0.945). Non-transfused infants took significantly higher iron intake compared to infants receiving ${\geq}100mL/kg$ erythrocyte transfusion (p<0.001). Minimum and maximum serum ferritin levels of non-transfused infants were higher than those of infants receiving <100 mL/kg erythrocyte transfusions (p=0.026 and p=0.022, respectively). Infants with morbidity including bronchopulmonary dysplasia or retinopathy of prematurity received a significantly higher volume of erythrocyte transfusions compared to infants without morbidity (p<0.001). Conclusion: Very low birth weight infants undergoing multiply erythrocyte transfusions had excessive iron stores and non-transfused infants also might had a risk of iron overload during hospitalization in the NICU.

관절염 이환자돈과 건강한 모돈으로부터 분리한 Streptococci의 균종 및 항균제 내성 (Prevalence of Streptococci in arthritic piglets and healthy sows with reference to antibiotic resistance of isolates)

  • 조현주;여상건
    • 대한수의학회지
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    • 제29권3호
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    • pp.315-324
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    • 1989
  • In order to establish the extent of Streptococcal arthritis piglets, isolation of Streptococci from arthritic lesions of 34 piglets were undertaken from November 1987 to October 1988 in Korea. Also determined were isolation frequency of Streptococci in nasal cavity of 250 healthy sows and antibiotic susceptibilities of the isolates. Streptococci were isolated from 52.9% of 34 arthritic piglets and 20 strains isolated belonged to 4 S suis type I, 8 S suis type II, 2 Lancefield group C and 6 group E. From 28.8% of 250 healthy sows, 72 strains of Streptococci were isolated and these consisted of 9 S suis type I, 51 S suis type II and 12 group C. Streptococcal arthritis seemed to occur prominently in piglets aged 2 to 4 weeks and in male than female. No significant difference were recognized in tarsal and carpal joints as affecting site. All of 92 isolates were sensitive to ampicillin and penicillin, and all strains of S suis type I and group E Streptococcus were also sensitive to chloramphenicol and cephalothin. To cephalothin all strains of group C Streptococcus were sensitive. The 1. 7 to 100% of 92 isolates were resistant with different prevalence to colistin, erythromycin, kanamycin, tetracycline, gentamicin, chloramphenicol and cephalothin. The 92.5% of these resistant Streptococci were multiply drug-resistant strains. The drug resistant patterns most frequently encountered were Tc Cl Em Km Gm(16.3%) in quintuple pattern, Tc Cl Em Km(16.3%) in quadruple pattern, Tc Cl Em(10.9%) in triple pattern and Cl Em(14.1%) in double pattern.

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XY 스캐너의 아베 오차 최소화를 위한 최적 설계 및 나노 정밀도의 원자 현미경 피치 측정 불확도 평가 (Optimal design of a flexure hinge-based XY AFM scanner for minimizing Abbe errors and the evaluation of pitch measuring uncertainty of a nano-accuracy AFM system)

  • 김동민;이동연;권대갑
    • 한국정밀공학회지
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    • 제23권6호
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    • pp.96-103
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    • 2006
  • To establish of standard technique of nano-length measurement in 2D plane, new AFM system has been designed. In the long range (about several tens of ${\mu}m$), measurement uncertainty is dominantly affected by the Abbe error of XY scanning stage. No linear stage is perfectly straight; in other words, every scanning stage is subject to tilting, pitch and yaw motion. In this paper, an AFM system with minimum offset of XY sensing is designed. And XY scanning stage is designed to minimize rotation angle because Abbe errors occur through the multiply of offset and rotation angle. To minimize the rotation angle optimal design has performed by maximizing the stiffness ratio of motion direction to the parasitic motion direction of each stage. This paper describes the design scheme of full AFM system, especially about XY stage. Full range of fabricated XY scanner is $100{\mu}m\times100{\mu}m$. And tilting, pitch and yaw motion are measured by autocollimator to evaluate the performance of XY stage. As a result, XY scanner can have good performance. Using this AFM system, 3um pitch specimen was measured. The uncertainty of total system has been evaluated. X and Y direction performance is different. X-direction measuring performance is better. So to evaluate only ID pitch length, X-direction scanning is preferable. Its expanded uncertainty(k=2) is $\sqrt{(3.96)^2+(4.10\times10^{-5}{\times}p)^2}$ measured length in nm.

다중 심벌 검파를 이용한 트렐리스 부호화된 대역 확산 통신 시스템 (Trellis Coded Spread Spectrum with the multiple symbol detection)

  • 김상태;김종일
    • 한국정보통신학회논문지
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    • 제4권3호
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    • pp.517-526
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    • 2000
  • 본 논문에서는 직접대역확산통신시스템에서 코딩 이득을 향상시키고자 다중 심벌 검파를 수행하는 트렐리스 부호화 변조를 적용하였다. $MDPSK(\pi/4 shift QPSK)$를 트렐리스 부호화된 직접대역확산시스템 적용하고 정보가 인접한 채널 신호의 위상차에 전송된다는 것을 이용하여 1차 위상차 뿐만 아니라 다중위상차를 추출한다. BER특성을 향상시키기 위해, 이러한 다중 위상차를 이용하여 $MDPSK(\pi/4 shift QPSK)$에서 다중 심벌 검파를 수행하는 트렐리스 부호화된 직접대역확산시스템의 비터비 디코더 알고리듬을 설계하여 향상된 코딩 이득을 얻고자 한다. 이러한 시스템을 직접대역확산통신시스템에 적용하였을 때 얻을 수 있는 코딩 이득은 시뮬레이션 결과, AWGN채널에서 TCM의 콘볼류션부호화기의 상태수 4, 8, 16에 따라 3-4dB 정도의 성능향상이 있으며, 레일레이 페이딩 채널에서는 4-5dB정도의 성능 향상이 있음을 알 수 있다. 일반적으로 상태수가 증가할수록 더 큰 코딩 이득을 얻을 수 있다.

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ATM 네트워크에서 POBP 방식을 이용한 대역폭 할당 방법의 성능분석 (Performance Analysis of Bandwidth Allocation Scheme using POBP Method in ATM Networks.)

  • 한상엽;박광채
    • 한국정보통신학회논문지
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    • 제4권3호
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    • pp.537-548
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    • 2000
  • ATM은 다양한 전송속도의 트래픽을 통계적으로 다중화하여 효과적으로 수용할 수 있는 경제적인 정보 전달 방식이다. 그러나 일시적인 과부하시 큰 셀 손실 및 셀 지연이 발생할 수 있다. 따라서 사용자 관점에서 서비스 품질 보장과 망 관점에서 이용 효율의 극대화라는 상반된 내용에 대해서 효과적인 트래픽 제어와 망 자원관리가 요구된다. 본 논문에서는 ATM스위치 네트워크를 2단을 기본으로 구성하였을 때 혼합되어진 각 서비스 클래스에 대한 서비스 품질을 보장하기 위하여 ATM Forum에서 권고하는 반응제어 기법인 BP(Back Pressure) 방법과 pushout 메커니즘을 혼합한 POBP(PushOut BP) 방법을 제안하였다. 제안한 방법에서는 대역폭의 사용 현황을 실 시간적으로 정확하게 파악하여 협정이 이루어 져야 한다. 이러한 과정을 통하여 잔여 대역폭을 효과적으로 사용할 수 있을 뿐만 아니라 공정한 대역폭의 사용을 보장하여 2단 ATM 네트워크에서의 폭주 상태로 인한 셀 손실률을 개선할 수 있었다.

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직접순차 확산 스펙트럼 시스템에서 데이터 재순환 적응 횡단선 필터의 LMS 알고리즘을 이용한 고속 수렴 속도 개선 (The Improvement of High Convergence Speed using LMS Algorithm of Data-Recycling Adaptive Transversal Filter in Direct Sequence Spread Spectrum)

  • 김광준;윤찬호;김천석
    • 한국정보통신학회논문지
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    • 제9권1호
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    • pp.22-33
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    • 2005
  • 본 논문에서 직접순차 확산 스펙트럼 시스템의 적응 횡단선 필터에서 LMS 알고리즘의 수렴 속도를 향상시키기 위한 효율적인 신호간섭 제어기법을 제안한다. 수신 데이터를 재순환하여 심볼 시간주기에 계수들을 곱함으로써 적응되는 제안된 알고리즘의 수렴특성이 수렴 속도의 향상을 이론적으로 증명하기 위해 분석한다. 스텝-크기 매개변수 ${\mu}$가 증가됨에 따라 알고리즘의 수렴 속도가 제어된다. 또한, 스텝-크기 매개변수 ${\mu}$의 증가는 실험적으로 계산된 학습 곡선에서 분산을 감소시키는 효과를 갖는다. 고유치 확산을 증가시킴에 따라 즉응 등화기의 수렴속도를 천천히 제어하고 평균 자승 에러의 안정-상태 값을 증가시키는 효과를 나타내며 데이터-재사용 LMS 기술이 수렴속도를 (B+1)배만큼 증가시켜 필터 알고리즘에서 신호간섭제어의 우수성을 입증한다.

경작지 근권 토양내 곤충병원성 선충의 검출 및 정량적 평가 (The Detection and a Quantitative Evaluation of Entomopathogenic Nematodes in Cultivated Rhizosphere Soil)

  • 황경숙;한상미;김윤지;남필원;한송이
    • 환경생물
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    • 제21권3호
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    • pp.271-275
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    • 2003
  • 유기농업을 수행해온 배추와 무의 근권토양과 관행농법의 근권토양 및 비경작지 토양으로부터 토양시료를 채취하여 선충의 밀도를 조사하고, 토양내 유익선충인 곤충병원성 선충의 분포상황을 검토하였다. 경작지 토양 내 선충 분포율이 비경작지에 비하여 높았고, 유기농업 토양이 관행농업 토양보다 선충의 밀도가 높게 나타났다. 선충의 정량적 평가법으로 직접계수법과 MPN 법을 비교 조사한 결과 MPN법이 신속하고 정확한 방법임이 확인되었다. 각 토양으로부터 분리된 곤충병원성 선충은 Rhabditida목 선충과 Diplogasterida목 선충으로 분류되었다. 이들 선충 중 Diplogasterida목 선충이 50% 이상을 차지하여 높은 점유율을 나타내었다. 누에를 기주체로 사용한 살충력 검정에 있어 24∼36시간 이내에 90%이상의 기주 치사율을 보여 농작물 해충방제를 위한 생물농약으로의 활용 가능성을 나타내었다.

Natural occurrence of Mycobacterium as an endosymbiont of Acanthamoeba isolated from a contact lens storage case

  • Yu, Hak-Sun;Jeong, Hae-Jin;Hong, Yeon-Chul;Seol, Seong-Yong;Chung, Dong-Il;Kong, Hyun-Hee
    • Parasites, Hosts and Diseases
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    • 제45권1호
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    • pp.11-18
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    • 2007
  • Recent in vitro studies have revealed that a certain Mycobacterium can survive and multiply within free-living amoebae. It is believed that protozoans function as host cells for the intracellular replication and evasion of Mycobacterium spp. under harmful conditions. In this study, we describe the isolation and characterization of a bacterium naturally observed within an amoeba isolate acquired from a contact lens storage case. The bacterium multi-plied within Acanthamoeba, but exerted no cytopathic effects on the amoeba during a 6-year amoebic culture. Trasnmission electron microscopy showed that the bacteria were randomly distributed within the cytoplasm of trophozoites and cysts of Acanthamoeba. On the basis of the results of 18S rRNA gene analysis, the amoeba was identified as A. lugdunensis. A 16S rRNA gene analysis placed this bacterium within the genus Mycobacterium. The bacterium evidenced positive reactivity for acid-fast and fluorescent acid-fast stains. The bacterium was capable of growth on the Middlebrook 7H11-Mycobacterium-specific agar. The identification and characterization of bacterial endosymbionts of free-living protozoa bears significant implications for our understanding of the ecology and the identification of other atypical mycobacterial pathogens.

Strategies to Multiply Elite Cow in Hanwoo Small Farm

  • Lee, Seung Hwan;Kim, Ui Hyung;Dang, Chang Gwan;Aditi, Sharma;Kim, Hyeong Cheul;Yeon, Seung Heum;Jeon, Gi Jun;Chang, Sun Sik;Oh, Sung Jong;Lee, Hak Kyo;Yang, Bo Suk;Kang, Hee Seol
    • 한국수정란이식학회지
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    • 제28권2호
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    • pp.79-85
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    • 2013
  • The recent development in genetic assisted selection (combining traditional- and genome assisted selection method) and reproduction technologies will allow multiplying elite cow in Hanwoo small farm. This review describes the new context and corresponding needs for genome assisted selection schemes and how reproductive technologies can be incorporated to get more genetic gain for cow genetic improvement in Hanwoo. New improved massive phenotypes and pedigree information are being generated from commercial farm sector and these are allowing to do genetic evaluation using BLUP to get elite cows in Korea. Moreover cattle genome information can now be incorporated into breeding program. In this context, this review will discuss about combining the reproductive techniques (Multiple Ovulation Embryo Transfer; MOET) and genome assisted selection method to get more genetic gain in Hanwoo breeding program. Finally, how these technologies can be used for multiplication of elite cow in small farm was discussed.

예인식 심해용 비디오카메라를 이용한 대게의 서식밀도 추정 (Estimation of the distribution density of snow crab, Chionoecetes opilio using a deep-sea underwater camera system attached on a towing sledge)

  • 안희춘;이경훈;배재현;배봉성;신종근
    • 수산해양기술연구
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    • 제45권3호
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    • pp.151-156
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    • 2009
  • This study shows that the distribution density of snow crab, Chionoecetes opilio, was estimated using an underwater video monitoring system attached on the towing sledge. The field experiments were carried out at the coastal waters around Chuksan, East Sea, where ranged from 110 to 130m depth during September and October 2007. The sledge was towed for 40 minutes and the towing speed was controlled between 1.5 to 1.7 knot and each research areas were calculated to multiply towed distance by the detection width of the video monitoring system(1.2m), and then, distribution density of snow crab in each observations were estimated as a counted number of crab per 1,000$m^2$. The result shows that their survey, taken between two months, reflected similar results during survey period, and the maximum and mean distribution densities in September estimated to be 77.0(number/1,000$m^2$) and 19.9, respectively, and those of October were 36.0 and 21.8, respectively.