• Environmental Engineering Research
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• v.23 no.3
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• pp.309-315
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• 2018

Chlortetracycline (CTC) is one of the most important compounds in antibiotic production, and its distribution has been widely investigated due to health and ecological concerns. This study presents systematic approach to optimize the high-performance liquid chromatography-tandem mass spectrometry for analyzing CTC in a multiple reaction monitoring mode ($479{\rightarrow}462m/z$). One-factor-at-a-time (OFAT) test with response surface analysis (RSA) was used as optimization strategy. In OFAT tests, the fragmentor voltage, collision energy, and ratio of acetonitrile in the mobile phase were selected as major factors for RSA. The experimental conditions were determined using a composite in cube design (CCD) to maximize the peak area. As a result, the partial cubic model precisely predicted the peak area response with high statistical significance. In the model, the (solvent composition) and (collision $energy^2$) terms were statistically significant at the 0.1 ${\alpha}$-level, while the two-way interactions of the independent variables were negligible. By analyzing the model equation, the optimum conditions were derived as 114.9 V, 15.7 eV, and 70.9% for the fragmentor voltage, collision energy, and solvent composition, respectively. The RSA, coupled with the CCD, offered a comprehensive understanding of the peak area that responds to changes in experimental conditions.

• Architectural research
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• v.21 no.2
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• pp.49-57
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• 2019

Risk assessment during pre-construction phase is important due to the uncertainty of the risks that may exist in projects. Risk checklist is a method to systematically classify and organize the risks that have been experienced in the past, and to identify the risk factors that may be present in the future projects. In addition, risk value assessment based on checklists plays a key role in risk management, and various risk assessment researches have been conducted to carry out this systematically. However, previous approaches have limitations in common, this is because risk values are evaluated individually in risk checklists, which ignore interdependencies among risk factors and neglect the emergence of co-occurrence of risks. Hence, when multiple risk factors cooccur, they cannot be far off from the conventional method of summing the total risk value to establish the risk response strategy. Most of risk factors are interdependent and may have multiple effects if occurred than expected. In particular, specific cause can be overlapped if multiple risks co-occur, and this may result in overestimation of the risk response for the future project. Thus, the objective of this research is to propose a model to help decision makers to quantify the risk value reflecting the interdependency during the identification phase using existing risk checklist that is currently being practiced in actual construction projects. The proposed model will provide the guideline to support the prediction and identification of the interdependency of risks in practice. In addition, the better understanding and prediction of the exceeding risk response by co-occurring risks during the risk identification phase for decision makers.

• Journal of applied mathematics & informatics
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• v.8 no.2
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• pp.613-625
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• 2001

In this paper, we investigate a simplified model of a particle suspended elastically from two towers by two nonlinear elastic springs, with a restoring force similar to Hooke’s law under extension and with no resistance to compression. Numerical results are presented, showing the solutions can be either of the same period oscillation the forcing term, can be a subharmonic response of multiple period, or can be noisy periodic which is apparently chaotic. Multiplicity of periodic solutions for certain physical parameters are demonstrated.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.4A
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• pp.611-622
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• 2008

Nonlinear analyses have been carried out for both bridge piers and a bridge structure being repaired using a repair element in order to assess the post-repair seismic response of such structures. For this purpose, a simplified CFRP stress-strain model has been proposed. The analytical predictions incorporating the current developments correlate reasonably well with experimental results in terms of strength and stiffness. In addition, nonlinear dynamaic analyses have also been conducted for a bridge structure in terms of the created multiple earthquake sets to evaluate the effect of pier repair on the response of a whole bridge structure. In these analyses, potential plastic hinge zones of piers are virtually repaired by CFRP and steel jacketing. Comparative results prove the virtual necessity of performing nonlinear post-repair analyses under multiple earthquakes, particularly when the post-repair response features are required. In all, the present approaches are expected to provide salient information regarding a healthy seismic repair intervention of a damaged strcuture.

• Journal of Korean Elementary Science Education
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• v.32 no.2
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• pp.139-158
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• 2013

This study investigated elementary students' (grade 4~6) learning progressions for water cycling drawn from iterative assessments using ordered multiple-choice (OMC) items. An assessment system, which consisted of construct map, item design, outcome space, and measurement model, was employed in this study to examine children's learning progressions. At the first stage of the assessment system, a construct map was designed on which children's conceptual understandings from naive to most sophisticated were represented. At the item design stage, 8 OMC items were drawn from the construct map. Each item option of the OMC items was scored from 0 to 3 according to its level of understanding at the stage of outcome space. As a measurement model, Rasch model, a branch of item response theory, was applied to interpreting the outcomes of the OMC items. This cycle of assessment system was furtherly implemented iteratively in order to elaborate on the first version of water cycling learning progression. In conclusion, children's understanding of water cycling could be described in two aspects: water distribution and water movement. We identified children's conjectural developmental pathways about water cycling existed from superficial and naive accounts to more complex and abstract accounts.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.16 no.3
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• pp.271-280
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• 2003

The purpose of the study presented in this paper is to develope the general model for capture of the linear and nonlinear response of a flexible diaphragm building in which there are significant contributions from the out-of-plane walls. Two single-story single-diaphragm half scale reinforced masonry buildings were tested by researchers at the United States Army Construction Engineering Research Laboratory (CERL). The first had a metal deck diaphragm. The second specimen had a diaphragm with a single layer of diagonal lumber sheathing, A multiple degree of freedom (MDOF) approach is adopted in this paper. The required stiffnesses and strengths of the components within this model are determined.

• Journal of Korean Institute of Industrial Engineers
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• v.43 no.2
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• pp.127-134
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• 2017

For product or process design and development, it is common to optimize multiple responses (characteristics) based on experimental data. To determine optimal conditions, we need to design the experiment, estimate a proper model for each response, and optimize the multiple responses simultaneously. There are several techniques and many research results on optimizing multiple responses simultaneously, when the experimental data are available. However, the experimental design issue for optimizing multiple responses has not been discussed yet. This paper proposes some idea on how to plan screening design when requirements for multiple performance characteristics are to be met in developing new products. A screening design procedure is developed for securing the requirements of multiple responses. Initial design factors are classified into three categories; specific, non-conflicting common, and conflicting common. After screening experiments, follow-up design region search method is suggested with respect to the most unsatisfied or important response, or overall desirability. A case study on a synthesis of melamine formaldehyde resin is presented to illustrate the procedure and to show the validity of the approach.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.49 no.4
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• pp.185-194
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• 2000

The learning automaton is an automaton to update systematically the strategy for enhancing the performance in response to the output results, and several schemes of learning automata have been presented. In this paper, S-model learning automata are applied in order to achieve the best compromise solution between an optimal solution for economic operation and an optimal solution for stable operation of the power system under the circumstance that the loads vary randomly. It is shown that learning automata are applied satisfactorily to the multiobjective optimization problem for obtaining the best tradeoff among the conflicting economy and stability objectives of power systems.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.29 no.1 s.232
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• pp.139-144
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• 2005

A vehicle cruise control algorithm using an Interacting Multiple Model (IMM)-based Multi-Target Tracking (MTT) method has been presented in this paper. The vehicle cruise control algorithm consists of three parts; track estimator using IMM-Probabilistic Data Association Filter (PDAF), a primary target vehicle determination algorithm and a single-target adaptive cruise control algorithm. Three motion models; uniform motion, lane-change motion and acceleration motion. have been adopted to distinguish large lateral motions from longitudinal motions. The models have been validated using simulated and experimental data. The improvement in the state estimation performance when using three models is verified in target tracking simulations. The performance and safety benefits of a multi-model-based MTT-ACC system is investigated via simulations using real driving radar sensor data. These simulations show system response that is more realistic and reflective of actual human driving behavior.

• Journal of computational fluids engineering
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• v.15 no.2
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• pp.79-85
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• 2010

Aerodynamic design optimization of rotor airfoil has been performed with advanced design method for improved aerodynamic characteristics of ONERA airfoils. A multiple response surface method is used to consider various requirements in rotor airfoil design. Shape functions for mean camber line are proposed to extend possible design domain. Numerical simulations are performed using KFLOW, a Navier-Stokes solver with shear stress transport turbulence model. The present design method provides favorable configurations for the high performance rotor airfoil. Resulting optimized airfoils give better aerodynamic performance than the baseline airfoils.