In the biopharmaceutical contract manufacturing organization (CMO) business, establishing a production schedule that satisfies the due date for various customer orders is crucial for competitiveness. In a CMO process, each order consists of multiple batches that can be allocated to multiple production lines in small batch units for parallel production. This study proposes a meta-heuristic algorithm to establish a scheduling plan that minimizes the total delivery delay of orders in a CMO process with identical parallel machine. Inspired by biological evolution, the proposed algorithm generates random data structures similar to chromosomes to solve specific problems and effectively explores various solutions through operations such as crossover and mutation. Based on real-world data provided by a domestic CMO company, computer experiments were conducted to verify that the proposed algorithm produces superior scheduling plans compared to expert algorithms used by the company and commercial optimization packages, within a reasonable computation time.
Purposes: This study was performed to understand the recognition about accreditation motives, support within the hospital and accreditation survey process for the hospitals that participated in the accreditation program and to find out whether these factors are related to hospital management performances, so that the study can suggest plans for activation and development of the accreditation program. Methodology: This study was performed targeting 98 hospitals answered th the survey among 189 acute care hospitals that acquired accreditation from December 2010 to February 2014. For data analysis, frequency analysis, ${\chi}^2$-test, reliability analysis, ANOVA, Kruskal-Wallis H test and multiple regression analysis with SPSS 21.0 were used. Findings: The hospitals that had staff in charge of patient safety had bigger hospital culture change than those that didn't have(p<.05). In addition, the hospital culture change was bigger as internal motives were bigger, and as CEO's will was bigger(p<.05). Meanwhile, as maintenance rate of internal management after accreditation was higher, and as CEO's will was bigger, process improvement level was higher(p<.05). The quality improvement and patient satisfaction level were higher as CEO's will was bigger, and as suitability of survey process was recognized to be high(p<.05). As a result of analyzing the factors that affect hospital management performances with hospital culture change, process improvement and quality improvement combined, as internal management maintenance rate was higher, as CEO's will was bigger, and as suitability of survey process was higher, performances were higher(p<.05). Practical Implications: Hospitals need to reinforce internal motives to improve internal competences such as the whole system maintenance opportunity and staff training. In addition, the will of hospital director is most important, and if there is hospital director's interest in quality improvement and improvement intention definitely, employees voluntarily participate in and cooperate with the accreditation program, so that prompt medical service provision and high quality of medical services can be guaranteed, leading to hospitals' management performances.
The semiconductor manufacturing process normally includes a great number of complex sequential steps those are related with various types of equipment. Such equipments are installed with the mixed patterns of serial or parallel structures while considering a number of engineering or environmental factors at the same time. It is thus extremely difficult to change the layout after installation due to expensive costs and other related factors. Because of these reasons, a new investment or layout change, which is usually caused by the production policy such as product mix or production quantity, must be carefully considered. This case study introduces a simulation conducted in a semiconductor parts production company which produces the Board on Chip (BOC)-type of packaging substrate and has plans to change the facility layout. For this study, we used $QUEST^{(R)}$ for simulation modeling and evaluated various strategies which may cause layout changes. Further, the Analytic Hierarchy Process (AHP) is applied to select the best strategy from several alternatives with multiple decision criteria.
Adegoriola, Mayowa I.;Yung, Esther H.K.;Lai, Joseph H.K.;Chan, Edwin H.W.
International conference on construction engineering and project management
/
2022.06a
/
pp.992-1000
/
2022
Heritage buildings (HBs) as structures with historical and architectural relevance that form an integral part of contemporary society. HBs deserve to be protected for as long as possible to retain their significance. Therefore, prioritizing HB maintenance management (HBMM) is pertinent. However, the decision-making process of HBMM can be relatively daunting. The decision-making challenge may be attributed to the multiple 'stakeholders' expectation and requirement which needs to be met. To this end, professionals in the built environment have identified the need to apply the strategic concept of facilities management (FM) in decision making. However, studies exploring the application of FM in decision-making seem lacking. To bridge this gap, this study focuses on developing a framework for strategic decision-making HBMM, which helps achieve HBMM sustainability. At the study's inception, relevant works of literature in the domains of HBMM and FM were conducted. This review helped identify contemporary maintenance practices and their applicability to HBMM. Afterward, a conceptual framework to aid decision-making in HBMM was developed. This framework integrated the concept of FM scope (people, place, process, and technology) while ensuring that decisions and plans were made at strategic, tactical, and operational levels. The conceptual framework presents a holistic guide for professionals in HBMM to ensure that decision processes and outcomes are practical and efficient. It also contributes to the existing body of knowledge on the integration of FM in HBMM. Furthermore, it will help achieve HB sustainability through an effective decision-making process.
While the field of mathematics education strives to promote equitable mathematics learning and identifies it as a core instructional practice, less is known about its effective enactment. As teachers' teaching practices are dependent on their views and beliefs, this study investigated 133 elementary pre-service teachers' (PSTs') interpretations of diverse learners' learning experiences and proposed accommodations for them as reflected in their lesson planning process. Findings showed that PSTs came up with some strategies that are often suggested in teacher education literature, such as using multiple modes of representation and various grouping strategies. However, their responses were generic in nature rather than specific to diverse learners. Also, it was noted that many PSTs' interchangeably referred to the English Language Learners (ELLs), struggling learners, and culturally diverse learners, inferring that they thought that culturally diverse students must have been ELLs and that ELLs or culturally diverse students must have been weaker students in math. We found that the PSTs used their own frames while filtering and discarding information about diverse student populations to develop instructional plans, rather than based on the results of assessments of learning. We suggest that it is the critical first step to unwrap PSTs' unproven assumptions to better equip them for working with all of their future students.
After World War II, modular housing was developed as a means of quickly and efficiently meeting the housing supply demand. For the past 30 plus years, efforts have been made to improve modular housing in South Korea and to increase their competitiveness in the housing market. This study investigated modular houses based on a steel framed rahem structure which provides a flexible floor plan where walls are easily reconfigured to create rooms of various sizes and functions. Similar to the factory production methods used in the automotive industry, the modular housing industry can also benefit by standardizing such aspects as building components, manufacturing and construction methods, materials, process management, and floor plans. This study examined the feasibility of using a 3m × 3m module for developing various floor plans which are easy to produce and transport. Each 3m × 3m module can be configured to meet different living needs resulting in a complete home when multiple modules are connected. The module configurations can be varied to meet ground transportation and crane limitations. This study found that a 3m × 3m steel framed modular unit is a promising step towards providing residents with plans that meet their living preferences while improving and increasing the supply of modular houses.
Pilot-scale coagulation and sedimentation processes were operated to investigate the T-P (Total phosphorus) removal efficiency. A multiple regression model was also derived to predict the water quality improvement effect with river water characteristics. The inflow rates for the pilot-scale facility were 157-576 m3/day, and the coagulant doses were in the range of 13.7-58.5 mg/L (average 38.9 mg/L) for PAC (Poly alum chloride) and 16.5-62.1 mg/L (average 36.0 mg/L) for alum. The results found that the influent BOD (Biochemical oxygen demand) and T-P concentrations were 4.9 mg/L and 0.115 mg/L, and the removal efficiencies were 52.7% and 59.4%, respectively. T-P removal efficiencies on wet weather days were higher by 10% than dry weather days because influent solids influenced T-P's coagulation process. The pH of river water was 6.9-7.8, and the average pH was 7.3. Although the pH variation was not significant, the trend showed that the treatment efficiency of T-P and PO4-P removal increased. Thus, the pH range considered in this study seems to be appropriate for the coagulation process, which is essential for phosphorous removal. The T-P removal efficiencies were 19.6-93.3% (average 59.2%) for PAC and 16.4-98.5%(average 55.9%) for alum; thus, both coagulants showed similar results. Furthermore, the average coagulant doses were similar at 42.4 mg/L for PAC and 41.3 mg/L for alum. When the T-P concentration of the effluent was compared by the [Al]/[P] ratio, the phosphorus concentration of the treated water decreased with an increasing [Al]/[P] ratio, and the lowest T-P concentration range appeared at the [Al]/[P] ratio of 10-30. A seasonal multiple regression analysis equations were derived from the relationships between 10 independent and dependent variables (T-P concentration of effluent). This study could help lake water quality maintenance, reduce eutrophication, and improve direction settings for urban planning, especially plans related to developing waterfront cities.
This study was conducted to explore the impact of learning strategies on the level of participation in the online collaborative learning process. To do this, We studied 91 students who took professorship courses at A university in the Seoul metropolitan area. At the beginning of the semester, the learning strategies were measured through MSLQ, rehearsal, elaboration, organizing, critical thinking, metacognition, learning management, effort control, peer learning, and seeking help. Next, cooperative tasks were carried out to measure the interaction, and group composition consisted of 4-5 persons. The level of participation was measured by scores given to the messages created for interaction. The process of collaborative learning was divided into the steps of identifying learning goals, learning plans, performing individual learning, sharing learning results, and writing reports. The effects of learning strategies on participation level were analyzed through multiple regression analysis (stepwise selection method). As a result, the learning goal step influenced the highest level of metacognition, and the learning plan is the management of the learning time, the demonstration of the learning execution, the adjustment of the effort, the acquisition of help, the collegial learning, Writing was influenced by organization, elaboration, critical thinking, and critical thinking, metacognition, and elaboration.
Korean Journal of Construction Engineering and Management
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v.23
no.1
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pp.46-53
/
2022
The railway platform is an important facility closely related to the safety of passengers, trains, and images of railway facilities, and requires thorough facility management. However, the problem that the finishing material (plastering mortar) for the joint finishing of dissimilar materials (concrete+granite) falls off in the direction of the track at the platform podium is occurring multiple times across the country. Since these problems threaten the safety of train operation and the safety of passengers, immediate and continuous management is required. This study tried to derive improvement plans through the analysis of the drop-off problem of finishing materials occurring at the platform podium. The status of missing finishing materials for the platform podiums of about 200 railway stations and the related design and construction standards of the Korea National Railway were investigated. After that, the cause of the drop-off of the finishing material was analyzed, and as a result, it was found that the main cause was the boundary between the roadbed and the architectural process that occurred during construction. Subsequently, in connection with the derived causes and design, construction standards, (1) improvement of finishing materials or construction methods, (2) design of finishing materials that are easy to adjust height, (3) design of separate finishing methods, (4) improvement methods and durability were suggested.
Korean Journal of Construction Engineering and Management
/
v.4
no.2
s.14
/
pp.99-108
/
2003
Recently, the construction companies are forced to cut down the investment amount due to increasing financial problems caused by severe recession and restructuring in the financial market as well as the long-term depression of the construction industry. To overcome this type of problems, a great many efforts have been made. An alternative may be adopting the advanced financing methods. However, during the course of enforcing process of the financing methods, many problems are revealed without any proper solutions being proposed. Therefore, the fundamental problems need to be solved through comprehensive and systematic approach under the changing environment of construction financing. In this paper, as a result of reviewing some financing methods such as ABS, REITS, and Project Financing, multiple business strategies for construction companies to cope with the changing construction market are found in the sense of effectiveness in implementing construction projects. Further, this paper presents diversified financing methods for the effective practice of construction projects through combination of above mentioned methods, and also proposes improvement plans to strengthen the financing function for the construction industry.
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