• Title/Summary/Keyword: Multiple linear Regression

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Associations of Non Alcoholic Fatty Liver with the Metabolic Syndrome and Serum Carotenoids (비알코올성 지방간과 대사증후군 및 혈청 카로테노이드와의 관련성)

  • Park, Sun-Kyun;Lee, Hyun-Jung;Lee, Duk-Hee;Lee, Sung-Kook;Chun, Byung-Yeol;Kim, Sung-Ae;Lee, Hye-Sung;Son, Hyo-Kyung;Kim, Sung-Hi
    • Journal of Preventive Medicine and Public Health
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    • v.41 no.1
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    • pp.39-44
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    • 2008
  • Objectives : This study was conducted to investigate the associations of non alcoholic fatty liver with metabolic syndrome and the serum carotenoids. Methods : This study was conducted in a general hospital in South Korea from November, 2004 to August, 2005. The study subjects were 350 sampled persons who were aged from 40 years and older (males : 180, females : 170). They were grouped into the normal, mild and severe groups according to fat accumulation in their livers, as determined by ultrasonography. We analyzed the association between non alcoholic fatty liver and metabolic syndrome by multiple logistic regression analysis and we analyzed the association between non alcoholic fatty liver and the serum carotenoids by a general linear model(ANCOVA). Results : After adjustment for the effect of potential covariates, the prevalence of metabolic syndrome was associated with fat accumulation in the liver (p trend <0.001). If the odds ratio of normal group is 1.00, then that of the mild group is 2.80 (95% C.I=1.17-6.71) and that of the severe group is 7.29 (95% C.I=2.76-19.30). The prevalence of metabolic alterations fitting the criteria of metabolic syndrome, according to the class of fat accumulation in the liver, was significantly increased, except for criteria of high blood pressure, a large waist circumference and low HDL (high density lipoprotein) cholesterol level (p trend <0.001). The level of serum ${\beta}$-carotene was decreased according to the class of fat accumulation in the liver (p trend=0.036), but the levels of serum ${\alpha}$-carotene, lycopene, ${\beta}$-cryptoxanthin and lutein were not decreased. Conclusions : This study shows that non alcoholic fatty liver was associated with metabolic syndrome and with the serum ${\beta}$-carotene level.

Optimization of the Extraction Process and Antioxidant Capacity of Coptis chinensis Franch Extract through Cluster Analysis (클러스터 분석을 이용한 황련 추출물 항산화 활성 최적화 추출공정)

  • Fu, Minmin;Xuan, Song Hua;Park, Soo Nam
    • Applied Chemistry for Engineering
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    • v.29 no.5
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    • pp.604-612
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    • 2018
  • Coptis chinensis Franch is a valuable traditional oriental medicinal plant used for the treatment of various diseases. The major factors affecting the content of bioactive compounds and the relationship between bioactive compounds and antioxidant capacities of Coptis chinensis Franch were poorly understood. Thus, effects of the solvent, temperature, and extraction time on the extraction yields of bioactive compounds and the antioxidant activity of C. chinensis Franch extracts were investigated in this work. Our cluster analysis indicated that the hydroalcoholic solvent (50% ethanol : 50% water) at $35^{\circ}C$ for 30 min (extract time) was the best extraction condition for a factory use because the highest level of bioactive compounds and antioxidant activities was achieved. Multiple linear regression analysis revealed that total phenolic content (TPC) contributed to the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) scavenging activity, while both total alkaloid content (TAC) and total flavonoid content (TFC) were responsible for ferric reducing antioxidant power (FRAP) activity. These results indicated that extraction conditions controlled the yield of bioactive compounds and the antioxidant activity of C. chinensis Franch, which can provide important information for the industrial extraction.

Breast Radiotherapy with Mixed Energy Photons; a Model for Optimal Beam Weighting

  • Birgani, Mohammadjavad Tahmasebi;Fatahiasl, Jafar;Hosseini, Seyed Mohammad;Bagheri, Ali;Behrooz, Mohammad Ali;Zabiehzadeh, Mansour;meskani, Reza;Gomari, Maryam Talaei
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7785-7788
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    • 2015
  • Utilization of high energy photons (>10MV) with an optimal weight using a mixed energy technique is a practical way to generate a homogenous dose distribution while maintaining adequate target coverage in intact breast radiotherapy. This study represents a model for estimation of this optimal weight for day to day clinical usage. For this purpose, treatment planning computed tomography scans of thirty-three consecutive early stage breast cancer patients following breast conservation surgery were analyzed. After delineation of the breast clinical target volume (CTV) and placing opposed wedge paired isocenteric tangential portals, dosimeteric calculations were conducted and dose volume histograms (DVHs) were generated, first with pure 6MV photons and then these calculations were repeated ten times with incorporating 18MV photons (ten percent increase in weight per step) in each individual patient. For each calculation two indexes including maximum dose in the breast CTV ($D_{max}$) and the volume of CTV which covered with 95% Isodose line ($V_{CTV,95%IDL}$) were measured according to the DVH data and then normalized values were plotted in a graph. The optimal weight of 18MV photons was defined as the intersection point of $D_{max}$ and $V_{CTV,95%IDL}$ graphs. For creating a model to predict this optimal weight multiple linear regression analysis was used based on some of the breast and tangential field parameters. The best fitting model for prediction of 18MV photons optimal weight in breast radiotherapy using mixed energy technique, incorporated chest wall separation plus central lung distance (Adjusted R2=0.776). In conclusion, this study represents a model for the estimation of optimal beam weighting in breast radiotherapy using mixed photon energy technique for routine day to day clinical usage.

The Convergent Effect of Self-esteem, Depression, and Social support on Suicidal ideation in University Students (대학생의 자아존중감, 우울, 사회적 지지가 자살사고에 미치는 융복합적 영향)

  • Lee, Sun-young;Kim, Yun-young;Lee, Jeong-sook
    • Journal of Digital Convergence
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    • v.15 no.8
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    • pp.323-331
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    • 2017
  • The purpose of the study was to investigate the effect of self-esteem, depression, and social support on suicidal ideation in university students. A self-reported questionnaire was completed by 220 university students from September to November 2015. The study instruments comprised self-esteem, depression, social support, and suicidal ideation. The data were analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation coefficients, and multiple linear regression using SPSS/WIN 21.0 program. The result showed that the difference of suicidal ideation by general characteristics was significant in major satisfaction(F=5.222, p=.006). The significant factors influencing suicidal ideation of university students were self-esteem(${\beta}=-0.227$, p=.004), depression(${\beta}=0.211$, p=.006), social support(${\beta}=-0.140$, p=.045), and with the explanation power of 21.9%. To decrease suicidal ideation of university students, it is necessary to develop a program increasing the self-esteem and managing the depression. The interest and social support of them will help the healthy promotion of university students.

Practice of Skin Cancer Prevention among Road Traffic Police Officers in Malaysia

  • Al-Naggar, Redhwan Ahmed
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4577-4581
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    • 2013
  • Background: The objective of this study was to determine the practice of skin cancer prevention among Malaysian road traffic police officers. Materials and Methods: This cross-sectional study involved 202 Malaysian Road Police Traffic officers. Inclusion criteria were those officers who work wearing white uniform regulating traffic. The survey took place at the Police Traffic Station, Jln Tun H.S. Lee, Kuala Lumpur, the main Head Quarters of Malaysian's Traffic Department where almost 600 police traffic officers are employed. The police traffic officers are given the task to take care of the traffic from the main office of the police station, then, according to the task, the officers drive to their given location for their duty. Each task is approved by the Chief Traffic Inspector of Kuala Lumpur. Data collected in this study were analyzed using SPSS 13, with the T-test for univariate analysis and multiple linear regression for multivariate analysis. Results: A total of 202 road traffic police officers participated. The majority were older than 30 years of age, male, Malay, married, with secondary education, with monthly income more than 2000 Ringgit Malaysia (66.3%, 91.1%, 86.6%, 84.7%, 96%, 66.3%; respectively). Regarding the practice of skin cancer prevention, 84.6% of the study participants were found to wear hats, 68.9% sunglasses and 85.6% clothing that covering most of the body but only 16.9% used a sunscreen when they were outdoors. When analysis of the factors that influenced the practice of skin cancer prevention was performed, univariate analysis revealed that gender, age and monthly income significantly influenced the practice of skin cancer prevention. For multivariate analysis, gender, monthly income and race significantly influenced the practice of using sunscreen among road traffic police officers (p<0.001, p=0.019, p=0.027; respectively). Conclusions: The practice of skin cancer prevention among the traffic police officers showed good practices in terms of wearinga hat, sun glasses and clothing that covers most of the body. However, the study revealed a poor practice of the use of sunscreen. The factors that influence the practice of sunscreen use were found to be gender, income, and race. The study suggests that more awareness campaign among traffic police officers is needed. Providing sunscreen for free for police traffic officers should be considered by the Police authorities.

Maternal Weight Gain Pattern and Birth Weight (임신 삼분기별 산모의 체중 증가 양상과 신생아 체중과의 상관 관계)

  • Kim, Mok-Jin;Lee, Ho-Yeol;Lee, Young-Gi;Park, Yoon-Kee;Lee, Doo-Jin;Lee, Sung-Ho
    • Journal of Yeungnam Medical Science
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    • v.15 no.1
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    • pp.135-142
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    • 1998
  • Maternal weight gain during pregnancy has been consistently associated with infant birth weight and pregnancy outcome. Our purpose was to determine the relationship between maternal weight gain pattern and birth weight. Consequently, maternal weight gain is monitored carefully and is encouraged during prenatal care in order to improve pregnancy outcome. Our study group included both 424 uncomplicated women and infant delivered at the Yeungnam University Hospital between 1993-1996. All recorded prenatal weight gain measurements were used to estimate maternal trimester weight gain, pattern of gain (based on low versus not-low gain at each trimester), and total gain at delivery. Multiple linear regression analysis was used to assess the relationship between these weight gain measurements and fetal birth weight. Each kilogram of maternal gain in the first, second, and third trimesters was associated with statistically related to the increase in fetal birth weight by 31.3, 19.0, and 24.5g, respectively. When compaired with the pattern of gain that was not low in any trimester, patterns with low gain in the first trimesters were associated with significant decreases in birth weight, but no important change in birth weight was seen for the group whose gains were not low in the first trimester. The results suggest that specific patterns of maternal weight gain, particularly weight gain during the first trimester, are related to fetal birth weight.

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Secular Trends and Influencing Factors for the Early Menarche among Korean Middle and High School Girls (우리나라 중고등학교 여학생의 조기 초경 경향과 영향요인)

  • Han, Dallong;Lee, Jongeun;Kim, Seonho
    • The Journal of the Korea Contents Association
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    • v.16 no.3
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    • pp.319-327
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    • 2016
  • The objective of this study is to identify the secular trend in age at menarche and to investigate the factors influence the early menarche(<12 years old) among Korean middle and high school girls. We analyzed data from the Korean Youth Risk Behavior Web-based Survey(KYRBWS) 2006-2014. This study was a descriptive study of 216,917 Korean middle and high school girls born between 1988 and 2002. Linear trends test performed to assess the trend age at menarche and percentage of early menarche. Multiple logistic regression analysis was to assess the risk factors influence the early menarche. Mean age at menarche decreased from $12.61{\pm}1.32$ years for middle and high school girls born 1988 to $11.88{\pm}0.75$ years for those born 2002(p for trends<.001). Percentage of early menarche increased from 19.7% to 25.2% between 1988 and 2002(p for trends<.001). Living in city, higher stress level, short sleep duration, and higher body mass index were associated with an early menarche among middle and high school girls(all p<.001). We found that age at menarche is still falling in the Korean adolescents, and it need intervention strategies to control the early menarche.

The Long-Term Stability of the Lower Incisor Axis in Class II division 2 Malocclusions (제II급 2류 부정교합에서 하악 절치 치축의 장기적인 안정성에 관한 연구)

  • Choi, Won-Cheul;Kim, Tae-Woo
    • The korean journal of orthodontics
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    • v.34 no.6 s.107
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    • pp.497-505
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    • 2004
  • The purpose of this study was to evaluate the post-retention stability of the lower incisor axis in Class II division 2 malocclusions. The dental casts and lateral cephalograms from before (T1) and after (T2) orthodontic treatment and long-term post-retention (T3) in 62 Class II division 2 malocclusion cases were included in this study. After several linear and angular measurements at each time were taken, the significance in the amount of change of the lower incisor axis for each gender and extraction versus non-extraction was evaluated. The results showed that the lower incisors that inclined labially during treatment were unstable and relapsed to the original lingual position in Class II division 2 malocclusions (p<0.001). There was no significant difference between extraction and non-extraction groups for the amount of lingual relapse of the lower incisors (p>0.05). There was no significant difference between male and female groups for the axial change of the lower incisors (p>0.05). As a result of multiple regression analysis, the cephalometric measurement best predicting the lower incisor position to the A-Pog line post-retention was pre-treatment L1-Apog(mm) and pre-treatment SNGoMe$(^{\circ})$. Because of the instability of labially inclined lower incisors after orthodontic treatment, the treatment goal should be the pre-treatment incisor axial position.

Correlation analysis between energy indices and source-to-node shortest pathway of water distribution network (상수도관망 수원-절점 최소거리와 에너지 지표 상관성 분석)

  • Lee, Seungyub;Jung, Donghwi
    • Journal of Korea Water Resources Association
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    • v.51 no.11
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    • pp.989-998
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    • 2018
  • Connectivity between water source and demand node can be served as a critical system performance indicator of the degree of water distribution network (WDN)' failure severity under abnormal conditions. Graph theory-based approaches have been widely applied to quantify the connectivity due to WDN's graph-like topological feature. However, most previous studies used undirected-unweighted graph theory which is not proper to WDN. In this study, the directed-weighted graph theory was applied for WDN connectivity analyses. We also proposed novel connectivity indicators, Source-to-Node Shortest Pathway (SNSP) and SNSP-Degree (SNSP-D) which is an inverse of the SNSP value, that does not require complicate hydraulic simulation of a WDN of interest. The proposed SNSP-D index was demonstrated in total 42 networks in J City, South Korea in which Pearson Correlation Coefficient (PCC) between the proposed SNSP-D and four other system performance indicators was computed: three resilience indexes and an energy efficiency metric. It was confirmed that a system representative value of the SNSP-D has strong correlation with all resilience and energy efficiency indexes (PCC = 0.87 on average). Especially, PCC was higher than 0.93 with modified resilience index (MRI) and energy efficiency indicator. In addition, a multiple linear regression analysis was performed to identify the system hydraulic characteristic factors that affect the correlation between SNSP-D and other system performance indicators. The proposed SNSP is expected to be served as a useful surrogate measure of resilience and/or energy efficiency indexes in practice.

A Study on the Hydroclimatic Effects on the Estimation of Annual Actual Evapotranspiration Using Watershed Water Balance (유역 물수지를 이용한 연 실제증발산 산정에 미치는 수문기후 영향 연구)

  • Rim, Chang-Soo;Lim, Ga-Hui;Yoon, Sei-Eui
    • Journal of Korea Water Resources Association
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    • v.44 no.12
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    • pp.915-928
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    • 2011
  • The main purpose of this study is to understand the effects of hydroclimatic factors on annual actual evapotranspiration and to suggest the multiple linear regression (MLR) equations for the estimation of annual actual evapotranspiration from watershed. To accomplish this study purpose, 5 dam watersheds (Goesan dam, Seomjingang dam, Soyanggang dam, Andong dam, Hapcheon dam) were selected as study watersheds and annual actual evapotranspiration was estimated based on annual water balance analysis from each watershed. The estimated annual actual evapotranspiration from water balance analysis was used to evaluate the MLR equations. Furthermore, the possibility of the estimation of actual evapotranspiration using potential evapotranspiration equations (Penman equation, FAO P-M equation, Makkink equation, Preistley-Taylor equation, Hargreaves equation) was evaluated. It has turned out that it is not appropriate to use potential evapotranspiration for the estimation of actual evapotranspiration because the correlation between actual evapotranspiration and potential evapotranspiration is very low. The comparison of MLR equations with current actual evapotranspiration equations indicates that MLR equations can be used for the estimation of annual actual evapotranspiration. Furthermore, it has turned out that the effects of hydroclimatic factors on annual actual evapotranspiration from dam watersheds are different in each watershed; however, for all watersheds in common precipitation has turned out to be the most important climatic factor affecting on the estimation of annual actual evapotranspiration.