• 한국컴퓨터정보학회논문지
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• 제19권7호
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• pp.47-57
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• 2014

정보보안 (인터넷 혹은 사이버) 위협 레벨을 공지하기 위해 많은 정보보안 회사들은 위협 계수기(Threat Meter)를 개발하였다. 본 논문에서는 물리보안 장치들이 지능화되고 네트워크를 통해 감시 및 제어가 가능함에 따라 물리보안의 현재 위협 수준을 결정하는 물리보안 위협 계수기(PSTM: Physical Security Threat Meter)를 제안한다. 따라서 PSTM은 정보보안에서 사용하는 위협 계수기와 유사하다. 이러한 목적을 위해 물리보안 이벤트를 분석하고 가중치를 결정하였으며 복수의 보안이벤트 발생에 따른 이벤트 간 시간 연관성 영향을 고려하였다. 또한 위협 레벨을 결정하기 위한 기준 값 설정 방법과 이들 기준 값을 이용한 실용적인 PSTM을 제안하였다. 특히 출입문 제어기와 CCTV(비디오 분석기 포함)로 구성된 실험환경에서 PSTM을 제작하기 위한 구체적인 블록도와 구현과정을 보임으로써 제안된 기법이 실현 가능함을 보였다. 마지막으로 몇몇 실험 시나리오를 대상으로 실시한 시뮬레이션 결과를 통해 제안된 PSTM이 물리보안 위협레벨을 적절히 공지함을 검증하였다.

• International Journal of Concrete Structures and Materials
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• 제9권3호
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• pp.345-367
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• 2015

Past earthquakes have signaled the increased collapse vulnerability of mainshock-damaged bridge piers and urgent need of repair interventions prior to subsequent cascading hazard events, such as aftershocks, triggered by the mainshock (MS). The overarching goal of this study is to quantify the collapse vulnerability of mainshock-damaged substandard RC bridge piers rehabilitated with different repair jackets (FRP, conventional thick steel and hybrid jacket) under aftershock (AS) attacks of various intensities. The efficacy of repair jackets on post-MS resilience of repaired bridges is quantified for a prototype two-span single-column bridge bent with lap-splice deficiency at column-footing interface. Extensive number of incremental dynamic time history analyses on numerical finite element bridge models with deteriorating properties under back-to-back MS-AS sequences were utilized to evaluate the efficacy of different repair jackets on the post-repair behavior of RC bridges subjected to AS attacks. Results indicate the dramatic impact of repair jacket application on post-MS resilience of damaged bridge piers-up to 45.5 % increase of structural collapse capacity-subjected to aftershocks of multiple intensities. Besides, the efficacy of repair jackets is found to be proportionate to the intensity of AS attacks. Moreover, the steel jacket exhibited to be the most vulnerable repair intervention compared to CFRP, irrespective of the seismic sequence (severe MS-severe or moderate AS) or earthquake type (near-fault or far-fault).

• 대한한방내과학회지
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• 제41권2호
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• pp.166-176
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• 2020

Objectives: This study reports on the effect of Integrative Medicine Therapy (IMT) on a patient with pancreatic cancer with liver metastasis. Methods: One pancreatic cancer with liver metastasis patient was treated using IMT in conjunction with Gemcitabine/Abraxane since September 2019. The cycle was repeated every four weeks for a total of 11 times. At the same time, the patient was treated with IMT. Tumor size was measured by scanning with Computed Tomography (CT). Adverse events were evaluated using the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE), version 5.0. Results: After treatment with Gemcitabine/Abraxane and IMT for eight months, the size of the body and tail of the cancer tumor and several hepatic metastatic regions decreased (partial response, [PR]), size, and number of multiple nodules in both lungs decreased. No evidence of newly developed metastatic lesions was found. The patient has maintained a good treatment outcome and has shown prolonged overall survival. Conclusions: This case demonstrates that treatment with IMT may have substantial benefits for patients with end-stage pancreatic cancer.

• Toxicological Research
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• 제26권1호
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• pp.21-28
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• 2010

As the frequency and the intensity of so called Asian dust (AD) events have increased, public concerns about the adverse health effects has spiked sharply over the last two decades. Despite the recent reports on the correlation between AD events and the risk for cardiovascular and respiratory disease, the nature of the toxicity and the degree of the risk are yet largely unknown. In the present study, we investigated the effects of the dichloromethane extract of AD (AD-X) and that of urban dust (NAD-X) collected during a non-AD period on gene expression in HL-60 cells using Illumina Sentrix HumanRef-8 Expression BeadChips. Global changes in gene expression were analyzed after 24 h of incubation with 50 or 100 ${\mu}g$/ml AD-X and NAD-X. By one-way analysis of variance (p < 0.05) and Benjamini-Hochberg multiple testing correction for false discovery rate of the results, 573 and 297 genes were identified as AD-X- and NAD-X-responsive, respectively. The genes were classified into three groups by Venn diagram analysis of their expression profile, i.e., 290 AD-X-specific, 14 NAD-X-specific, and 283 overlapping genes. Quantitative realtime PCR confirmed the changes in the expression levels of the selected genes. The expression patterns of five genes, namely SORL1, RABEPK, DDIT4, AZU1, and NUDT1 differed significantly between the two groups. Following rigorous validation process, these genes may provide information in developing biomarker for AD exposure.

• 한국전자거래학회지
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• 제14권4호
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• pp.315-332
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• 2009

물류 프로세스는 일반적인 비즈니스 프로세스와는 달리, 서로 이질적인 조직이 참여하여 프로세스를 진행한다는 특징을 보인다. 따라서 각 참여조직들 간의 상호작용을 제어하면서 프로세스를 수행하는 것이 필요하다. 프로세스의 실행이라는 측면에서 이를 제어하는 가장 좋은 대안으로 비즈니스 프로세스 관리(BPM) 시스템을 들 수 있으나, 참여조직 간의 프로세스 소유권과 접근 권한 관리 문제와 함께, 현재의 일반적인 상용 시스템들은 참여조직 간의 상호작용을 관리하기 위한 기능을 거의 제공하지 못한다는 문제점을 안고 있다. 또한 RFID 기술 기반의 물류 환경에서, RFID 이벤트의 적용과 처리를 지원하는 물류프로세스 관리에 대한 고려가 미흡한 실정이다. 따라서 본 연구에서는 물류 환경에서 발생하는 다조직 프로세스를 RFID 이벤트 기반의 통제를 위한 새로운 방법론을 제시하고자 한다. Interworkflow(워크플로우 간) 패턴으로 표현되는 참여조직들 간의 프로세스 자동 트리거링(Auto-Triggering)을 위하여 ECA(Event-Condition-Action) 규칙에 복합이벤트(Complex Event)를 활용한 RFID 이벤트 기반의 RFID-based ECA 규칙을 제공한다.

• 대한불안의학회지
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• 제11권1호
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• pp.61-68
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• 2015

Objective : Police officers are exposed to job-related traumatic events and have a high prevalence of post-traumatic stress disorder (PTSD). This study examined the relationship between PTSD symptoms and dimensions of temperament and character in police officers. Method : Thirty-six police officers participating in a psychological support program were enrolled. All subjects were asked to complete a demographic questionnaire, the Impact of Event Scale-Revised (IES-R), the Temperament and Character Inventory (TCI) and other self-reported symptoms scales. Results : Among all participants (age $40.8{\pm}10.2$, men 94.4%), the rate of 'post-traumatic stress symptoms group' was 47.2%. After controlling for confounding factors, lower self-directedness scores were significantly associated with higher PTSD symptoms (${\beta}=0.6$, p=0.03) in multiple regression analysis. Conclusion : Character traits, especially self-directedness, were associated with the severity of PTSD symptoms severity. These findings may provide useful information regarding personality factors related to PTSD in police officers.

• 한국산림과학회지
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• 제88권1호
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• pp.55-62
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• 1999

유니버시아드 대회와 같은 대형이벤트의 성공적인 개최는 국 내외 관광객의 대량 유업효과, 개최국가와 지역의 이미지 개선효과 이외에도 대회준비를 위한 사회간접시설의 조성으로 인한 지역경제 활성화를 도모하는 등 많은 외형적인 변화를 가져온다. 이러한 관점에서 본 연구는 1997년 무주에서 개최된 동계 유니버시아드대회가 개최지역인 농 산촌지역에 끼친 파급영향을 다측면적인 관점에서 분석하기 위하여 종단적인 시간비교연구를 실증적으로 수행하였다. 그 결과 지역주민들이 지각하는 동계유니버시아드 대회의 파급영향은 개최지역의 관광산업과 지역개발분야에서는 투자효과가 큰 것으로 나타났으나, 지역경제의 활성화 측면에서는 그다지 크게 성공적이지 못한 것으로 분석되었으며, 또한 개최지역인 덕유산국립공원의 자연환경에 피해를 준 것으로 평가되었다.

• 전기전자학회논문지
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• 제16권2호
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• pp.138-144
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• 2012

본 논문에서는 DSF 릴레이 MC-CDMA 시스템에 대한 의사 성능분석 기법을 다중경로 레일리 페이딩 채널에 대해 제안한다. 오류율 성능과 복잡도를 고려하여 MC-CDMA 시스템의 결합기법으로는 MMSE-C 방법을 사용한다. 평균 오류율 유도를 위하여 DSF-Relay 기법의 릴레이 노드들에서 발생할 수 있는 오류 사건에 기반한 분석 방법을 우선 채택한다. 그리고 발생가능한 모든 오류 사건들을 고려한 형태로 평균 오류율 표현한다. 또한 제안된 의사 분석적 성능분석 결과는 모의실험 결과와의 비교를 통하여 검증하도록 한다. 최종적으로 유도된 성능분석 결과가 다양한 다중경로 레일리 페이딩 채널 환경을 반영하면서 DSF 릴레이 MC-CDMA 시스템의 성능 상한 값을 측정할 수 있는 분석 툴이 될 수 있음을 확인한다.

• 한국임상약학회지
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• 제23권3호
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• pp.223-231
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• 2013

Objective: This study aimed to identify the status and risk factors of rituximab infusion-related adverse events (ADE) in rituximab-na$\ddot{i}$ve patients with cancer diseases. Method: A retrospective analysis using electronic medical records review was conducted. Inclusions were patients with a diagnosis of cancer disease with the initiation of rituximab-included treatment who were na$\ddot{i}$ve to rituximab during January 2011 to March 2013 at National Cancer Center (NCC) in Korea. Result: Total 110 patients, 582 cases of rituximab administrations, were reported in the study. About 57.2% of patients were 51-70 years old and evenly distributed between two genders and 72.7% were BMI less than $25kg/m^2$. All of study patients were diagnosed with non-Hodgkin lymphoma. Fifty patients (45.4%) and 54 cases (9.3%) were experienced rituximab infusion-related AEs even with conservative administration protocol at NCC. The most frequently occurring AEs were shivering followed by rash and itching. In single variant analysis, we found that the early stage of NHL, low exposure to rituximab administrations, high white blood cell counts, high lymphocyte counts, high absolute neutrophil count and low lactate dehydrogenase were associated with infusion-related AEs (p<0.05). The early stage of disease, high lymphocyte counts, low exposure to rituximab administrations were also related significantly with AEs in multiple variants analysis (p<0.05). Conclusion: Rituximab infusion-related AEs for patients who were na$\ddot{i}$ve to rituximab were still a concern with conservative administration protocol. The adverse drug reactions were significantly associated with early stage of NHL, higher lymphocyte counts and low exposure to rituximab administrations. The factors need to be considered with close monitoring to prevent rituximab infusion-related AE.

• 한국의류학회지
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• 제26권7호
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• pp.1066-1077
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• 2002

The Purposes of this study were 1) to identify the effects of clothing involvement on deal Proneness, store images related to promotions and perceived shopping value, and 2) to reveal the effects of antecedent variables on the consumer satisfaction. The data were collected from 624 female consumers living in Seoul, Korea via self-administered questionnaires and were analyzed by frequency, factor analysis, multiple regression analysis and path analysis. The results of the study were as follows : (1) Among the factors related to clothing involvement deal proneness, store images of promotions and perceived shopping values, Clothing importance, Shopping interest Fashion interest and all three factors of deal proneness had the effect on perceived hedonic shopping values. Clothing importance, Prudent purchase, Shopping interest store images related to promotions had the effects on perceived hedonic shopping values. And Prudent purchase had the positive effects and store images related to Display had the negative effects on perceived negative shopping values. (2) From the resulted of analyzing the effects of antecedent variables on consumer satisfaction, Sweepstakes/gifts proneness, store images related to Price discount/events and Display, perceived hedonic and utilitarian shopping values positive]y influenced the consumer satisfaction. Store images related to Price discount/events had the most significant effects on consumer satisfaction. From the results of path analysis, clothing involvement had the effects on consumer satisfaction indirectly through deal proneness, store images related to promotions and perceived shopping values.