• Title/Summary/Keyword: Multiple alignment

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ALMA observations of a proto-binary system, IRAS 04191+1523

  • Lee, Jeong-Eun;Lee, Seokho;Yoon, Sung-Yong;Dunham, Michael;Evans, Neal;Choi, Minho;Tatematsu, Ken;Bergin, Edwin
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.2
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    • pp.46.4-47
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    • 2016
  • About 50% of stars reside in binary or multiple systems. However, the formation mechanism of the multiplicity is poorly understood. Theoretical studies suggest two main mechanisms for the multiplicity: turbulent fragmentation and disk fragmentation. We can testify which mechanism is more plausible by measuring the separation between companions or the alignment of stellar spins. Here we present our ALMA Cycle 2 observational results of a proto-binary system, IRAS 04191+1523, which consists of two Class I sources. We detected disks around both Class I sources, which are located in a common dense filamentary structure traced by $C^{18}O$ J=2-1. Two protostellar disks are separated by ~900 AU and their rotational axes are almost perpendicular, which strongly support that this binary system formed by the turbulent fragmentation.

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A Sturdy on the Optimum Alignment in Multiple Antenna System (다중안테나의 최적배치에 관한 연구)

  • Kim Jong-Sung;Choi Won-Kyu;Whang Hee-Yong;Choi Se-Ha;Choi Kyung
    • 한국정보통신설비학회:학술대회논문집
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    • 2003.08a
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    • pp.272-277
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    • 2003
  • Two antennas system which is aligned in cross direction is tested and analyzed. The main scope is focused to get an appropriated distance between the two small antennas to get a better property. The theoretical expectation and the computer simulation are executed simultaneously. The target is the folded IF antenna system printed on PCB, but the ideal dipole-antenna arrangement is also tested to verify the possibility of our implementation. And it is finally proved by experiments.

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Prediction of epitope for Malaria based on bioinformatics (생물정보학기반 말라리아 항원부위의 예측)

  • Jo, Si Hyang;Kim, Hak Yong
    • Proceedings of the Korea Contents Association Conference
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    • 2014.11a
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    • pp.405-406
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    • 2014
  • 말라리아에 의한 감염 중 95% 이상을 차지하는 것은 열대열 원충과 삼일열 원충에 의한 감염이다. 각 원충들에 의한 감염은 초기증상이 유사하지만 각각의 치료방법이 다르게 적용되기 때문에 어떤 원충에 의한 발병인지 정확하고 빠른 진단이 필요하다. 본 연구에서는 생명정보학을 기반으로 각 원충에 특이적으로 발현되는 단백질 정보를 중심으로 epitope를 예측하고자 하였다. 먼저 NCBI에서 문헌조사 및 서열정보를 얻었으며, 두 원충에 대한 서열을 multiple alignment를 통해서 비교한 결과 90.2%의 유사성을 보였다. 확보된 특이 부위를 ProtScale Tool 프로그램을 이용하여 hydrophilicity를 분석하고 진단키트 제작에 사용할 수 있는 epitope를 예측하였다.

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Prediction of Epitope for Chikungunya Virus based on Bioinformatics (생물정보학기반 치쿤구니아 바이러스 항원결정부위의 예측)

  • Lee, Jihoo;Kim, Hak Yong
    • Proceedings of the Korea Contents Association Conference
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    • 2014.11a
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    • pp.55-56
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    • 2014
  • 치쿤구니아열은 치쿤구니아 바이러스(chikungu- nya virus)에 감염된 매개 모기(열대숲모기 및 흰줄숲모기)에 물려 감염되는 급성 열성 질환으로 잠복기가 짧고 치료제가 없기 때문에 조기 진단이 매우 중요한 급성전염병이다. 아열대기후로 진입하는 우리나라에서도 흰줄숲모기가 자주 발견되기 때문에 이 질병으로부터 결코 자유롭지가 않다. 치쿤구니아 바이러스 감염을 진단하기 위한 진단키트를 개발하기 위해 먼저 타깃 유전자 부위 선정이 매우 중요하다. 본 연구에서는 생명정보학을 기반으로 이 바이러스 만을 검출할 수 있는 epitope를 예측하고자 한다. 이 바이러스의 capsid 유전자를 찾고 유사한 바이러스의 유전자들과 multiple alignment를 수행하여 이 바이러스만이 가지고 있는 독특한 부위를 추출하였다. 이후 ProtScale Tool 프로그램으로 선택한 단백질의 친수성(hydrophilicity), 접근성(accessi- bility), 유연성(flexibility), 회전(${\beta}$-turns) 등의 특성을 모두 만족하는 부위를 선별하여 진단키트 제작을 위한 epitope를 제시하고자 한다.

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A Study on 3-D Shape Measurement and Application by Using Digital Projection Moire (II) (디지털 영사식 무아레를 이용한 3차원 형상 측정과 응용에 관한 연구(II))

  • Ryu, Weon-Jae;Kang, Young-June;Rho, Hyung-Min;Lee, Dong-Hwan
    • Journal of the Korean Society for Precision Engineering
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    • v.24 no.5
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    • pp.62-67
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    • 2007
  • A simple dimension measuring method for the measurement of human bust has been developed using projection moire. The 3-D data of a human bust was calculated from the 2dimensional image information obtained by the stripe using projection moire. The creation of 3-D geometric shape by digitizing real objects has been widely investigated in reverse engineering(RE). This procedure generally consists of three basic steps: data capture, data alignment and model reconstruction. In order to achieve a complete model, multiple scans must be taken and aligned.

Electro-optical characteristics of PVA (Z-shape) mode using the UV curable reactive mesogen (RM) (광경화성 단분자를 이용한 Z-shape PVA 모드에서의 투과율 향상에 관한 연구)

  • Cho, In-Young;Hwang, Seong-Jin;Kim, Sung-Min;Lee, Seung-Hee
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.06a
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    • pp.437-438
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    • 2008
  • The Conventional patterned vertical alignment (PVA) device shows a very high contrast ratio at normal direction and does not require rubbing process. However it has a disclination area in which the liquid crystal can be collision in the boundary domain region. In this paper, we studied PVA(Z-shape) device in which the liquid crystal can be tilted down in multiple directions stably because the surface pretilt angle is controlled by photopolymerization of the UV - curable reactive mesogen (RM) under a proper condition. Consequently, the device shows improved electro optical properties as compared to conventional PVA mode.

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A Simple Java Sequence Alignment Editing Tool for Resolving Complex Repeat Regions

  • Ham, Seong-Il;Lee, Kyung-Eun;Park, Hyun-Seok
    • Genomics & Informatics
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    • v.7 no.1
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    • pp.46-48
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    • 2009
  • Finishing is the most time-consuming step in sequencing, and many genome projects are left unfinished due to complex repeat regions. Here, we have developed BACContigEditor, a prototype shotgun sequence finishing tool. It is essentially an editor that visualizes assemblies of shotgun sequence fragment reads as gapped multiple alignments. The program offers some flexibility that is needed to rapidly resolve complex regions within a working session. The sole purpose of the release is to promote collaborative creation of extensible software for fragment assembly editors, foster collaborative development, and reduce barriers to initial tool development effort. We describe our software architecture and identify current challenges. The program is available under an Open Source license.

Molecular Characterization of Apolipophorin-III in the Fall Webworm, Hyphantria cunea Drury

  • Kim, Hong-Ja;Lee, Sang-Dae;Seo, Sook-Jae
    • International Journal of Industrial Entomology and Biomaterials
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    • v.3 no.2
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    • pp.163-168
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    • 2001
  • We isolated and sequenced a cDNA clone corresponding to apolipophorin-III (apoLp-III) from the fall webworm, Hyphantria cunea. The cDNA for apoLp-III codes fer a 187-residue protein (561 bp) with a predicted molecular mass of 20 kDa. The calculated isoelectric point is 8.76. Multiple alignment analysis of the amino acid sequence revealed that H. cunea apoLp-III is most similar to that of Spodoptera litura (71.5% identity), followed by that of Manduca sexta (69.7% identity). They share five amphipathic $\alpha$-helices that are proposed to play a critical role in the binding of apoLp-III to lipophorin.

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Cloning and Sequencing of the rph Gene Encoding RNase PH from Legionella pneumophila

  • Kim, Se-Jin;Lim, Jong-Seok;Cianciotto, Nicholas P.;Choe, Yong-Kyung
    • Journal of Microbiology
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    • v.37 no.4
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    • pp.218-223
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    • 1999
  • Legionella pneumophila, the cause of Legionnaires disease, is able to survive intracellularly in eukaryotic cells such as monocytes, macrophages, and protozoan organisms. During protein biosynthesis, the rph gene encodes ribonuclease (RNase) PH which functions as a phosphorolytic nuclease that removes nucleotides following the CCA terminus of tRNA and as a nucleotidyl-transferase which adds nucleotides to the ends of RNA molecules by usingnucelside diohosphates as substrates. In this sutdy, the rph gene was screened in pUC19 library employing a DNA probe which was constructed from PCR based on a consensus pattern of multiple alignment of RNas PH. The encoded protein consists of 235 amino acid residues with a calculated molecular weight of 26,112 Daltons. The RNase PH signature domains are completely conserved.

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A Novel Cross Channel Self-Attention based Approach for Facial Attribute Editing

  • Xu, Meng;Jin, Rize;Lu, Liangfu;Chung, Tae-Sun
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.15 no.6
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    • pp.2115-2127
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    • 2021
  • Although significant progress has been made in synthesizing visually realistic face images by Generative Adversarial Networks (GANs), there still lacks effective approaches to provide fine-grained control over the generation process for semantic facial attribute editing. In this work, we propose a novel cross channel self-attention based generative adversarial network (CCA-GAN), which weights the importance of multiple channels of features and archives pixel-level feature alignment and conversion, to reduce the impact on irrelevant attributes while editing the target attributes. Evaluation results show that CCA-GAN outperforms state-of-the-art models on the CelebA dataset, reducing Fréchet Inception Distance (FID) and Kernel Inception Distance (KID) by 15~28% and 25~100%, respectively. Furthermore, visualization of generated samples confirms the effect of disentanglement of the proposed model.