The purpose of this research investigates the determinant factors of the joint technology development project performance between SMEs and universities. Reviewing existing papers we could categorize independent variables into three groups of partner characteristics, process management variables and relationship characteristics between partners. Three measures of satisfaction with the cooperation result, the intention of continuing relationship and the utilization of developed technology and product were used as dependent variable considering that we studied the joint projects of SMEs' involvement, short period and small scale. The data was collected by questionnaire survey mailed to the 1082 SMEs and university professors which executed the joint projects sponsored by Small Business Administration in 2009. We received 200 responses from SMEs, and 305 cases from professors among which 55 responses of each partner were on the same project. We analyzed the data sets individually, data of SMEs and that of universities with multiple regression analysis technique and also analyzed the common responses of 55 projects. Analysis results of the data from SMEs indicated that partners' expertise, facilities and equipment, communications, strategic importance, and trust were significant variables for the project performance. Analysis results of the data from universities showed that previous links, definition of objectives, strategic importance, trust and commitment were significant variables. Analysis results of combined data of 55 projects from SMEs and universities indicated that facilities and equipment, project management proficiency and commitment were significant variables.
Objectives : Methods to evaluate obesity are growing to be important in studying links between health and disease. Physicians are using BMI (body mass index) to evaluate obesity, but they can't know how much fat the body has by using that method. Even though there are several assessments, there are different scales, so patients are diagnosed as obese, by some but not by others. These studies are limited in evaluating obesity; it is necessary to study based on new knowledge. According to Oriental Medical Theory, obese people are categorized into 3 types, Fei, Kao and Liu Ren. They have different pathology and body shapes than non-obese people. The relationship between Oriental Medical Theory and BMI and assessment of body fat is a fundamental need to easily approach and treat obesity. Methods : At 00 Oriental Medical Center, 145 female subjects who intended to lose weight were given physical tests and grouped into 5 types of obesity. The physical tests were height measurement, BMI, body composition (body fat mass and lean body mass), skin elasticity and physical strength tests. One-way analysis of variance was done to compare the means of physical tests between the five types of obese women. There was some relationship between characteristics of the five types based on physical tests and Fei, Kao and Liu Ren based on Oriental Medical Theory. Least significant difference (LSD) was used in multiple comparisons. Results : 1. According to the skin elasticity test, obesity type 5 placed between obesity types 3 and 4 and obesity types 1 and 2. Obesity types 3 and 4 were in the low skin elasticity result group; obesity types 1 and 2 were in the high ones (p<0.1).Based on Oriental Medical Theory, Fei Ren and Kao Ren can be distinguished by skin elasticity degree. This result should form the basis of obesity diagnosis. 2. According to Oriental Medical Theory, Fei Ren is smaller than others. Based on height measurement, obesity types 3 and 4 were significantly lower than other obesity types (p<0.1), so there is a relationship between Fei Ren and obesity types 3 & 4. 3. There were significant differences between obesity type 2 and obesity type 4 in the body fat mass result (p<0.1). This study did not have large enough a sample size to distinguish Liu Ren. Conclusions : Further clinical research is necessary to study measurement methods of body shape type and skin elasticity for distinguishing Fei Ren from Kao Ren. The diagnosis and treatment based on the relationship of these types should be studied further.
Journal of the Korea Academia-Industrial cooperation Society
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v.10
no.10
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pp.2959-2965
/
2009
This research is based on the medical information record of a university hospital on analysis of outpatients, inpatients and delivery related information in gynecology area. The result of application having analysis of patients as basic material for hospital management is as follows. The number of new patients in average was 140.9, and as the year passes by, it seemed to decrease noticeably(p=0.000). In the first year (2001) the number was only 212.6, but increased to 140 by the year of 2007, showing increase of 80.9. The actual number of patients in the hospital was 124.6 in average and it showed noticeable decrease after each year (p=0.000), from 144.6 patients on the first year 2001, to 104.8 patients in 2007, showing approximately 40 patients decreased. Multiple regression analysis was performed having independent variables as characteristics of patients and cause of delivery related factors, and dependent variables as the number of patients in the hospital. According to analysis, the cause of affecting the number of patients in the hospital was selected as the number of new patients, the number of delivery per year. The reliability rate was recorded as 62.8%. Therefore, apart from the services on marketing and patient management which must come first, the effect of inviting them cannot be avoided, which directly links to trust resulting from the consideration to patients.
This study aims to identify which social information have significant influence on the improvement of recommendation trust and how these effects can be different according to the product involvement level. Based on the relevant literature reviews, this study posits four characteristics of recommendation trust, which are closeness, similarity, sincerity, and reputation, and established a research model for the relationship between social information and recommendation trust. And we found a moderating effect of product involvement on the relationship between social information and recommendation trust. 205 trust relationships(links) from 55 respondents of Google Docs. survey data have been collected and tested using multiple regression and hierarchical regression analysis. The results of our hypotheses testing are summarized as follows. Firstly, four social information characteristics of closeness, similarity, sincerity, and reputation have a significantly positive effect on recommendation trust. Secondly, a moderating effect of product involvement between recommendation trust and antecedents (e.g., closeness and reputation) of social information is significant. From the results, we provide theoretical and managerial implications, and suggestions for further research.
Objectives : This study was to examine factors affecting the job satisfaction of dental hygienists. Methods : The subjects in this study were dental hygienists who worked at dental hospitals, dental clinics and general hospitals in the city of Gwangju. A survey was conducted by mail from January 2 to March 2, 2007. Out of the collected data, 208 answer sheets were analyzed. Results : 1. The dental hygienists investigated got a mean of 3.20 on job satisfaction. Among the job satisfaction factors, relationship with patients ranked highest(3.79), followed by relationship with colleagues(3.62), working environments(3.39), future prospects(3.30), professional status (2.89), pay(2.82) and required workload(2.58). 2. Regarding links between general characteristics and job satisfaction, the older dental hygienists were more satisfied with professional status, pay, required workload and relationship with patients. By marital status, the married dental hygienists expressed better satisfaction at professional status than the unmarried ones. By education, those who were receiving college education or received the same or higher education were more gratified than the junior college graduates. By the total length of career, the dental hygienists whose length of career was longer were more gratified with professional status, future prospects and relationship with patients. By workplace, the dental hospital workers were more satisfied with working environments, and the general hospital employees were more gratified with pay. The dental hospital employees were better satisfied with future prospects as well. As to the impact of the length of career at the current workplace, there was a tendency that those who worked at their current workplaces for a longer time expressed better satisfaction with professional status, pay and relationship with patients. By monthly mean income, the larger income earners had a tendency to be better gratified with professional status, pay and relationship with patients. 3. The general characteristics that were selected as independent variables were identified as the factors that exercised an influence on the job satisfaction of the dental hygienists and made an about 14.0% prediction of it. Out of those factors, the total length of career and monthly mean income had a statistically significant impact on that. Conclusions : The above-mentioned findings suggested that out of the seven job satisfaction components, they gave the lowest marks to satisfaction level with pay. As a result of making a multiple regression analysis, it's found that job satisfaction was under the influence of the total length of career and monthly mean income. Therefore there should be an improvement in the pay system in order to boost the job satisfaction of dental hygienists, and they should be paid properly in accordance with total length of career.
Journal of The Korean Association For Science Education
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v.24
no.6
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pp.1216-1234
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2004
School science practical work is often criticized as lacking key elements of authentic science, such as peer argumentation or debate through which social consensus is obtained. The purpose of this paper is to review the recent studies about the argumentation and to explore the conditions and the model of argumentative scientific inquiry, which is specially designed open inquiry in order to facilitate students' peer argumentation. For this purpose, a theoretical discussion for the argumentative scientific inquiry as the way of authentic inquiry in schools was developed. The conditions for argumentative scientific inquiry were found to be the following: multiple arguments, students' own claims, opportunities for oral and written argumentation, equal status of debaters, and community of cooperative competition. For these conditions, the argumentative scientific inquiry was organized into experiment activities and argumentation activities. During argumentation activity, students should be guided to advance written argumentation through writing a group report for peer review and oral argumentation through a critical discussion. Through the argumentation between groups and in group, the students' arguments would be elaborated repeatedly. The feedback from argumentation links experiment activities to argumentation activities. Hence, the whole process of this inquiry model is circular.
STATs are proteins with a dual function: signal transducers in the cytoplasm and transcriptional activators in the nucleus. Among the six known major STATs (STAT1-6), STAT3 has been implicated in the widest range of signaling pathways that regulate cell growth and differentiation. As a part of our on-going investigation on the pleiotropic functions of STAT proteins, we examined the role of STAT3 as a molecular adaptor that links diverse cell growth signaling pathways. We observed that STAT3 can be specifically activated by multiple cytokines, such as IL-3, in transformed fibroblasts and IL-4 or IFN-$\gamma$ in primary immune cells, respectively. The selective activation of STAT3 in H-ras-transformed NIH3T3 cells is associated with an increased expression of phosphoserioe STAT3 in these cells, compared to the parental cells. Notably phosphoresine-STAT3 interacts with oncogenic ras, shown by immunoprecipitation and Western blots. The results suggest the role of STAT3 in rasinduced cellular transformation as a molecular adaptor linking the Jak/STAT and Ras/MAPK pathways. In primary immune cells, IL-4 and IFN-$\gamma$ each induced (in addition to the characteristic STAT6 and STAT1 homodimers) the formation of STAT3-containing complexes that bind to GAS probes, which correspond to the $Fe{\varepsilon}$ Rll and $Fe{\gamma}$ RI promoter sequences, respectively. Since IL-4 and IFN-$\gamma$ are known to counter-regulate the expression of these genes, the ability of STAT3 to form heterodimeric complexes with STAT6 or STAT1 implies its role in the fine-tuned control of genes that are regulated by IL-4 and IFN-$\gamma$.
Background: Radix et Rhizoma Ginseng (thereafter called ginseng) has been used as a medicinal herb for thousands of years to maintain people's physical vitality and is also a non-organ-specific cancer preventive and therapeutic traditional medicine in several epidemiologic and preclinical studies. Owing to few toxic side effects and strong enhancement on body immunity, ginseng has admirable application potential and value in cancer chemoprevention. The study aims at investigating the chemopreventive effects of ginseng on cutaneous carcinoma and the underlying mechanisms. Methods: The mouse skin cancer model was induced by 7,12-dimethylbenz[a]anthracene/12-O-tetradecanoylphorbol-13-acetate. Ultraperformance liquid chromatography/mass spectrometry was used for identifying various ginsenosides, the main active ingredients of ginseng. Comprehensive approaches (including network pharmacology, bioinformatics, and experimental verification) were used to explore the potential targets of ginseng. Results: Ginseng treatment inhibited cutaneous carcinoma in terms of initiation and promotion. The content of Rb1, Rb2, Rc, and Rd ginsenosides was the highest in both mouse blood and skin tissues. Ginseng and its active components well maintained the redox homeostasis and modulated the immune response in the model. Specifically, ginseng treatment inhibited the initiation of skin cancer by enhancing T-cell-mediated immune response through upregulating HSP27 expression and inhibited the promotion of skin cancer by maintaining cellular redox homeostasis through promoting nuclear translocation of Nrf2. Conclusion: According to the study results, ginseng can be potentially used for cutaneous carcinoma as a chemopreventive agent by enhancing cell-mediated immunity and maintaining redox homeostasis with multiple components, targets, and links.
The seismic slope stability is most often evaluated by the pseudo-static limit analysis, in which the earthquake loading is simplified as static inertial loads acting in horizontal and/or vertical directions. The transient loading is represented by constant acceleration via the pseudostatic coefficients. The result of a pseudostatic analysis is governed by the selection of the value of the pseudostatic coefficient. However, selection of the value is very difficult and often done in an ad hoc manner without a sound physical reasoning. In addition, the maximum acceleration is commonly estimated from the design guideline, which cannot accurately estimate the dynamic response of a slope. There is a need to perform a 2D dynamic analysis to properly define the dynamic response characteristics. This paper develops a new hybrid pseudostatic method that links the modified one-dimensional seismic site response analysis and the pseudostatic algorithm. The modified site response analysis adjusts the density of the layers to simulate the change in mass and weight of the layers of the slope with depth. Multiple analyses were performed at various locations within the slope to estimate the change in seismic response of the slope. The calculated peak acceleration profiles with depth from the developed procedure were compared to those by the two-dimensional analyses. Comparisons show that the two methods result in remarkable match. The calculated profiles are used to perform pseudostatic analysis. The results show that use of peak or a fraction of acceleration at the surface can seriously underestimate or overestimate the factor of safety, and that the proposed procedure significantly enhances the reliability of a standard procedure.
The visibility graph is a well-known method for efficient path-finding with the minimum search space modelling the game world. The generalized visibility graph is constructed on the expanded obstacle boundaries to eliminate the "wall-hugging" problem which is a major disadvantage of using the visibility graph. The paths generated by the generalized visibility graph are guaranteed to be near optimal and natural-looking. In this paper we propose the method to apply the generalized visibility graph efficiently for game characters who moves among static obstacles between varying start and goal points. Even though the space is minimal once the generalized visibility graph is constructed, the construction itself is time-consuming in checking the intersection between every two links connecting nodes. The idea is that we build the map for static obstacles first and then incorporate start and goal nodes quickly. The incorporation of start and goal nodes is the part that must be executed repeatedly. Therefore we propose to use the rotational plane-sweep algorithm in the computational geometry for incorporating start and goal nodes efficiently. The simulation result shows that the execution time has been improved by 39%-68% according to running times in the game environment with multiple static obstacles.
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