• Title/Summary/Keyword: Multiple Effect

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Preventive Effect on Development of Diabetes and Renoprotective Effect of Acanthopanax Senticosus Aqua-acupuncture in Multiple Low-dose Streptozotocin-Induced Diabetic Rats (가시오가피약침(五加皮藥鍼)이 당뇨유발억제(糖尿誘發抑制) 및 신장보호활성(腎臟保護活性)에 미치는 영향)

  • Chung, Chong-un;Lee, Yun-ho;Kang, Sung-keel
    • Journal of Acupuncture Research
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    • v.20 no.3
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    • pp.1-14
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    • 2003
  • Objective : The aim of the study was to investigate the preventive effect of Acanthopanax senticosus(AS) aqua-acupuncture into Sinsu(BL23) of the multiple low-does strepozotocin(STZ)-induced diabetic rats. Methods : The experimental animals were divided into 4 groups : normal group of rats, control group of multiple low-does STZ-induced diabetic rats, NSAA group with 0.4ml normal saline(NS) aqua-acupunctured subcutaneously into Sinsu in multiple low-does STZ-induced diabetic rats, and ASAA group with 0.4ml of 20% AS aqua-acupunctured subcutaneously into Sinsu in multiple low-does STZ-induced diabetic rats. Each of AS and NS aqua-acupuncture was done subcutaneously into both loci of Sinsu taking turns everyday for 3 weeks. Thereafter the levels of serum glucose, body weight, index of kidney hypertrophy, urine glucose, urinary albumin excretion, creatinine clearance, mesangial cell and TGF-${\beta}1$ expression in glomeruli and tubular cells were measured on the determined day. Conclusions : 1. Both ASAA and NSAA groups decreased the serum glucose levels in multiple low-dose STZ-induced diabetic rats as compared to the cintrol group, and ASAA group showed more significant decreases than NSAA group. 2. Both ASAA and NSAA groups prevented the development of diabetes in multiple low-dose STZ-induced diabetic rats as compared to the control group, and ASAA group prevented more markedly the development of diabetes than NSAA group. 3. Both ASAA and NSAA groups prevented the reduction of body weight in multiple low-dose STZ-induced diabetic rats as compared to the control group, and ASAA group showed the same as the normal group. 4. Both ASAA and NSAA groups did not show any changes of the creatinine clearance in multiple low-does STZ-induced diabetic rats. 5. Both ASAA and NSAA groups prevented the excretion of urinary glucose and albumin in multiple low-dose STZ-induced diabetic rats as compared to the cintrol group, and ASAA group showed more significant prevention than NSAA group. 6. Both ASAA and NSAA groups prevented the expansion of glomerular cells and the protein expression of transforming growth factor-${\beta}1$ in multiple low-dose STZ-induced diabetic rats as compared to the cintrol group, and ASAA group prevented more significantly than NSAA group.

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Mediating Effect of Stress on Relationship between Emotional Intelligence and Burnout among Nursing College Students (일개 간호대학교 학생의 감성지능과 소진과의 관계에서 스트레스의 매개효과)

  • Ko, Chung Mee
    • Journal of the Korean Society of School Health
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    • v.28 no.3
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    • pp.239-247
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    • 2015
  • Purpose: The purpose of the study was to identify the effect of stress on the relations between emotional intelligence and burnout among nursing college students. Methods: The study is a cross-sectional survey and the participants were 363 students attending a nursing college located in Seoul. Data were collected by convenience sampling using self-reported questionnaires that consisted of general characteristics, emotional intelligence, perceived stress and burnout. Data were analyzed by descriptive statistics, t-test, ANOVA, correlation, and multiple regression. Results: Findings of the multiple regression were as follows. First, emotional intelligence had a significant negative-effect on stress. Second, emotional intelligence had a significant negative-effect on burnout. Third, stress had a significant positive-effect on burnout and had a mediating effect on the relationship between emotional intelligence and burnout. Conclusion: Results of the study suggest that as a way to reduce nursing college students' stress and burnout, programs which help improve nursing college students' emotional intelligence should be developed and implemented.

A Case Report of Partial Remission of Renal Cell Carcinoma with Multiple Liver Metastases Treated with Korean Herbal Medicine in Conjunction with Targeted Anticancer Therapy Afinitor (한약치료와 표적항암요법(아피니토)을 병행하여 부분 관해 된 신세포암 간전이 환자 1례)

  • Chang, Sung-Hwan;Park, Ji-Hye;Yoo, Hwa Seung
    • Journal of Korean Traditional Oncology
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    • v.22 no.2
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    • pp.13-24
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    • 2017
  • Objectives: The purpose of this study is to report the effect of Korean Herbal Medicine (KHM) on a Renal Cell Carcinoma with multiple liver metastases patient. Methods: One renal cell carcinoma with multiple liver metastases patient was treated by KHM in conjunction with targeted anticancer agent (Afinitor). The effect of KHM was measured by scanning with Computed Tomography (CT), Blood Test, Visual Analogue Scale (VAS) and Eastern Cooperative Oncology Group scale. Results: Multiple hepatic tumors were reduced after the treatment during 5 months (Partial Remission, PR). As treatment was performed, complications induced by targeted anticancer agent (Afinitor) were alleviated. Conclusions: This case provides us a possibility that Korean Herbal Medicine offers potential benefits for renal cell carcinoma with multiple liver metastases patient.

A Study on the Effect of Montessori-Education Program on Preschooler Multiple Intelligences (몬테소리 교육프로그램이 유아의 다중지능에 미치는 효과 연구)

  • Kim, Nam Su;Kwon, Eun Ju
    • Korean Journal of Childcare and Education
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    • v.1 no.1
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    • pp.59-81
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    • 2005
  • The purpose of this study was to examine how Montessori-education program, one of different early-childhood education programs, was tied into the multiple intelligences of young children and how Montessori education program affected their multiple intelligences. It's basically meant to determine the efficiency of Montessori-education program. The major findings of the study were as follows: First, the Montessori-education program turned out to have a favorable effect on the development of the young children's multiple intelligences. Second, among the subfactors of multiple intelligences, the musical and bodily-kinesthetic intelligences of the preschoolers were little affected by the Montessori-education program, but that had a good impact on their logical-mathematical, spatial, linguistic, interpersonal, intrapersonal, and naturalist intelligences. The above-mentioned findings suggested that Montessori-education program was one of efficient teaching methods to step up the development of young children's multiple intelligences.

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Estimating the Air Temperature Cooling Effect of the Cheonggyechun Stream Restoration Project of Seoul, Korea

  • Park Chong-Hwa;Kwon Young-Sang
    • Journal of the Korean Institute of Landscape Architecture International Edition
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    • no.2
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    • pp.120-129
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    • 2004
  • Urban stream restoration projects can improve water quality, wildlife habitats, urban landscape, outdoor recreation spaces, and urban microclimate. The objectives of this research were to investigate temperature cooling effect of urban streams by using satellite imagery, to evaluate environmental variables related to stream cooling effect, and to estimate the cooling effect of the Cheonggye stream restoration project of Seoul, Korea. Findings of this research can be summarized as follows. First, a method of estimating temperature distribution around urban streams by using satellite imagery was developed. Scatter plots of distance from stream edges and average temperature obtained through multiple buffering were used for the estimation. Second, urban temperature cooling effect of streams was estimated by comparing background temperature and temperature of each buffer zone. Third, environmental factors affecting stream cooling effect were also identified. Fourth, the temperature cooling effect of the restoration project was estimated based on three scenarios. An estimated cooling effect based on the average cooling effect of existing tributaries showed the most significant effect; $2.0^{\circ}C$ lower than the present level at the edge of the renovated stream. It was estimated that the temperature of the same area would be $1.4^{\circ}C$ cooler than the present level if the cooling effect of the Yangjaechun was used as the bench mark But the effect would be $1.2^{\circ}C$ lower than the present level if environmental variables related to the temperature cooling effect of urban streams were used as the bench mark.

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Environmental Test of Avionics Equipment for Lightning Indirect Effect (낙뢰 간접영향에 대한 항공전자장비의 환경시험)

  • Jeong, Duck-young;Yang, Hyun-duck
    • Journal of Aerospace System Engineering
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    • v.7 no.2
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    • pp.55-59
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    • 2013
  • Before avionics equipment are installed in aircraft, several environmental tests such as temperature, vibration, lightning, fire etc. must be conducted. One of the environmental tests is to substantiate protection designs of lightning indirect effect. It can be showed through RTCA DO-160G, section22 "Lightning Induced Transient Susceptibility" test. An additional test of aircraft level is required as well after installation of avionics equipment.

Effect of Red Ginseng Saponins on Learning Behavior of Rats in the Water Maze (랫트의 학습능력에 대한 홍삼 사포닌의 효과)

  • 진승하;남기열
    • Journal of Ginseng Research
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    • v.18 no.1
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    • pp.39-43
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    • 1994
  • This study was performed to investigate the effect of ginseng saponin from Korean red ginseng on the learning and memory. Total (50, 100 mg/kg, bw) and panaxadiol saponin (15, 30 mg/kg, bw) treated groups did not show the difference of the time score and the number of error in comparison with control group. Panaxatriol saponin (15, 30 mg/kg, bw) significantly decreased both the time score and the number of error in water maze test. These results indicate that panaxatriol saponin from Korean red ginseng may improve the learning ability of rat in water multiple T-maze.

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Hypoglycemic Effect of Ginseng Radix alba(GRA) in Multiple Low Dose Streptozotocin-induced Diabetic Rats

  • Park, Kyeong-Soo;Lee, Dong-Eok;Sung, Jung-Hwan;Chung, Sung-Hyun
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.261.2-261.2
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    • 2002
  • Hypoglycemic effect of GRA was examined in multiple low dose(MLD) streptozotocin(STZ)-induced diabetic rats with regard to time of administration. Experimental methods: 20 mg/kg of STZ in 100 mM citrate buffer(pH 4.5) was injected intraperitoneally for 5 consecutive days. In co-treatment groups, GRA was administered intraperitoneally for 3 weeks at dose of 150 or 300 kg/kg. (omitted)

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An analytical model for displacement response spectrum considering the soil-resonance effect

  • Zhang, Haizhong;Zhao, Yan-Gang
    • Earthquakes and Structures
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    • v.22 no.4
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    • pp.373-386
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    • 2022
  • The development of performance-based design methodologies requires a reasonable definition of a displacement-response spectrum. Although ground motions are known to be significantly affected by the resonant-like amplification behavior caused by multiple wave reflections within the surface soil, such a soil-resonance effect is seldom explicitly considered in current-displacement spectral models. In this study, an analytical approach is developed for the construction of displacement-response spectra by considering the soil-resonance effect. For this purpose, a simple and rational equation is proposed for the response spectral ratio at the site fundamental period (SRTg) to represent the soil-resonance effect based on wave multiple reflection theory. In addition, a bilinear model is adopted to construct the soil displacement-response spectra. The proposed model is verified by comparing its results with those obtained from actual observations and SHAKE analyses. The results show that the proposed model can lead to very good estimations of SRTg for harmonic incident seismic waves and lead to reasonable estimations of SRTg and soil displacement-response spectra for earthquakes with a relatively large magnitude, which are generally considered for seismic design, particularly in high-seismicity regions.

Moisturizing Effect and Durability of Sun Protection Factor (UVA/B) Activity with Multiple Emulsion (W/O/W) System (멀티플 에멀전(W/O/W) 시스템을 이용한 자외선차단성능(UVA/B)의 내수성과 보습효과)

  • Lee, Myoung-Hee;Kim, In-Young
    • Journal of the Korean Applied Science and Technology
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    • v.32 no.2
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    • pp.339-347
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    • 2015
  • This study is to evaluate moisturizing effect and durability of UV A/B blocking activity with multiple (W/O/W) emulsion system. Most of the sun protective products come to be hot issue having both high SPF and long-lasting activity as using special products when is going out, mountain climbing and sports. Also, many consumers prefer the products which have the excellent waterproofing activity of sun care cosmetics as well as the non-sticky feeling that carried out the study of the sensorial science and texture preference. Therefore, development of the specific formulation using this multiple (W/O/W) emulsion technology, it has O/W type hydro skin feel having soft and moist texture when it is treated on the skin. Finally, this formulation is instantly changed to W/O type feel after adsorbed into the skin. The purpose of this study is to get high SPF lasting effect having high water resistance tactivity with high functional multiple (W/O/W) emulsion cream. We used major ingredients, UV-B absorbers were selected with ethylhexyl methoxycinnamate, isoamyl-p-methoxycinnamate, ethylhexylsalicylate, and octocrylene, UV-A absorbers were selected with butylmethoxydibenzoylmethane, bis-ethylhexyloxyphenol methoxy phenyltriazine. SPF effect of O/W type cream was 34.1. SPF effect of W/O/W type cream was 40.6 (increased about 19%). Water resistance effect after 4 hours, SPF effect of O/W type cream was 3.6 (quickly drop down). SPF effect of W/O/W type cream having 81.0 % waterproofing effect was 32.7 (decreased about SPF 7.9). Moisturizing effect of O/W cream at first was superior comparing multiple emulsion. But after 3 hours quickly was drop-down. Moisturizing effect of multiple emulsion was high comparing O/W type and other sun block creams after 4 hours was constantly maintaining water-content.