• Asian-Australasian Journal of Animal Sciences
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• v.27 no.10
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• pp.1406-1410
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• 2014

Age at first calving is an important trait for achieving earlier reproductive performance. To detect quantitative trait loci (QTL) for reproductive traits, a genome wide association study was conducted on the 96 Hanwoo cows that were born between 2008 and 2010 from 13 sires in a local farm (Juk-Am Hanwoo farm, Suncheon, Korea) and genotyped with the Illumina 50K bovine single nucleotide polymorphism (SNP) chips. Phenotypes were regressed on additive and dominance effects for each SNP using a simple linear regression model after the effects of birth-year-month and polygenes were considered. A forward regression procedure was applied to determine the best set of SNPs for age at first calving. A total of 15 QTL were detected at the comparison-wise 0.001 level. Two QTL with strong statistical evidence were found at 128.9 Mb and 111.1 Mb on bovine chromosomes (BTA) 2 and 7, respectively, each of which accounted for 22% of the phenotypic variance. Also, five significant SNPs were detected on BTAs 10, 16, 20, 26, and 29. Multiple QTL were found on BTAs 1, 2, 7, and 14. The significant QTLs may be applied via marker assisted selection to increase rate of genetic gain for the trait, after validation tests in other Hanwoo cow populations.

• Korean Journal of Adult Nursing
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• v.26 no.1
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• pp.98-106
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• 2014

Purpose: The purpose of this study was to explore the effect of glove changing during surgery for colon cancer on reducing the degree of contamination of surgical gloves. Methods: The randomized posttest control group design was used. Total 72 surgeries of colon cancer in the K University Hospital in Seoul performed by the team of A-Surgeon and B-Scrub nurse were randomly assigned to one of the three groups. Glove changing with single-gloved state was implemented in the Experimental Group I and outer glove changing with double-gloved state was executed in the Experimental Group II. Single-gloved state was carried in the Control Group. Following the surgical procedure, specimens for bacterial culture were collected the from scrub nurse's gloves to compare the degree of contamination among the three groups. Data were analyzed with One-way ANOVA and the Scheff$\acute{e}$'s multiple comparison test. Results: The degrees of contamination of the Experimental Group I and II were significantly lower than that of the Control Group. There was no significant difference between Experimental Group I and II. Conclusion: Glove changing during surgery with either single or double-gloved state is effective in reducing the degree of contamination of surgical gloves, therefore these methods should be utilized in clinical practice.

• Journal of the Society of Naval Architects of Korea
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• v.33 no.4
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• pp.150-161
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• 1996

A numerical procedure is described for predicting steady drift forces on very large offshore structures supported by a large number of the floating bodies of arbitrary shape dimensional source distributing method, the wave interaction theory, the far-field method of using momentum theory and the finite element method for structurally treating the space frame elements. Numerical results are compared with the experimental or numerical ones, which are obtained in the literature, of steady drift forces on a offshore structure supported by the 33(3 by 11) floating composite vertical cylinders in waves. The results of comparison confirmed the validity of the proposed approach.

• Journal of Korean Institute of Industrial Engineers
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• v.28 no.3
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• pp.331-343
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• 2002

This paper proposes a fuzzy rule-based model as a means to build usability models between emotional satisfaction and design variables of consumer products. Based on a subtractive clustering algorithm, this model obtains partially overlapping rules from existing data and builds multiple local models each of which has a form of a linear regression equation. The best subset procedure and cross validation technique are used to select appropriate input variables. The proposed technique was applied to the modeling of luxuriousness, balance, and attractiveness of office chairs. For comparison, regression models were built on the same data in two different ways; one using only potentially important variables selected by the design experts, and the other using all the design variables available. The results showed that the fuzzy rule-based model had a great benefit in terms of the number of variables included in the model. They also turned out to be adequate for predicting the usability of a new product. Better yet, the information on the product classes and their satisfaction levels can be obtained by interpreting the rules. The models, when combined with the information from the regression models, are expected to help the designers gain valuable insights in designing a new product.

• Journal of the Korean Chemical Society
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• v.60 no.4
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• pp.225-234
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• 2016

The activity of 34 sulfonamide derivatives has been estimated by means of multiple linear regression (MLR), artificial neural network (ANN), simulated annealing (SA) and genetic algorithm (GA) techniques. These models were also utilized to select the most efficient subsets of descriptors in a cross-validation procedure for non-linear -log (IC50) prediction. The results obtained using GA-ANN were compared with MLR-MLR, MLR-ANN, SA-ANN and GA-ANN approaches. A high predictive ability was observed for the MLR-MLR, MLR-ANN, SA-ANN and MLR-GA models, with root mean sum square errors (RMSE) of 0.3958, 0.1006, 0.0359, 0.0326 and 0.0282 in gas phase and 0.2871, 0.0475, 0.0268, 0.0376 and 0.0097 in solvent, respectively (N=34). The results obtained using the GA-ANN method indicated that the activity of derivatives of sulfonamides depends on different parameters including DP03, BID, AAC, RDF035v, JGI9, TIE, R7e+, BELM6 descriptors in gas phase and Mor 32u, ESpm03d, RDF070v, ATS8m, MATS2e and R4p, L1u and R3m in solvent. In conclusion, the comparison of the quality of the ANN with different MLR models showed that ANN has a better predictive ability.

• Computers and Concrete
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• v.24 no.5
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• pp.423-436
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• 2019

Design equations to evaluate the bursting force in a post-tensioned anchorage zone have been introduced in many design codes, and one equation in AASHTO LRFD is widely used. However, this equation may not determine the bursting force exactly because it was designed on the basis of two-dimensional numerical analyses without considering various design parameters such as the duct hole and shape of the bearing plate. To improve the design equation, modification of the AASHTO LRFD design equation was considered. The behavior of the anchorage zone was investigated using three-dimensional linear elastic finite element analysis with design parameters such as bearing plate size and diameter of sheath hole. Upon the suggestion of a modified design equation for evaluating the bursting force in an anchorage block with a rectangular anchorage plate (Kim and Kwak 2018), additional influences of design parameters that could affect the evaluation of bursting force were investigated. An improved equation was introduced for determining the bursting force in an anchorage block with a circular anchorage plate, using the same procedure introduced in the design equation for an anchorage block with a rectangular anchorage plate. The validity of the introduced design equation was confirmed by comparison with AASHTO LRFD.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2655-2661
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• 2012

Validation of a food frequency questionnaire (FFQ) utilising a short-term measurement method is challenging when the reference method does not accurately reflect the usual food intake. In addition, food group intake that is not consumed on daily basis is more critical when episodically consumed foods are related and compared. To overcome these challenges, several statistical approaches have been developed to determine usual food intake distributions. The Multiple Source Method (MSM) can calculate the usual food intake by combining the frequency questions of an FFQ with the short-term food intake amount data. In this study, we applied the MSM to estimate the usual food group intake and evaluate the validity of an FFQ with a group of 333 Korean children (aged 3-6 y) who completed two 24-hour recalls (24HR) and one FFQ in 2010. After adjusting the data using the MSM procedure, the true rate of non-consumption for all food groups was less than 1% except for the beans group. The median Spearman correlation coefficients against FFQ of the mean of 2-d 24HRs data and the MSM-adjusted data were 0.20 (range: 0.11 to 0.40) and 0.35 (range: 0.14 to 0.60), respectively. The weighted kappa values against FFQ ranged from 0.08 to 0.25 for the mean of 2-d 24HRs data and from 0.10 to 0.41 for the MSM-adjusted data. For most food groups, the MSM-adjusted data showed relatively stronger correlations against FFQ than raw 2-d 24HRs data, from 0.03 (beverages) to 0.34 (mushrooms). The results of this study indicated that the application of the MSM, which was a better estimate of the usual intake, could be worth considering in FFQ validation studies among Korean children.

• Journal of the Korean Society of Systems Engineering
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• v.7 no.2
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• pp.7-11
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• 2011

A high-speed railway system represents a typical example of large-scale multi-disciplinary system, consisting of subsystems such as rolling-stock, electrical hardware, electronics, control, information, communication, civil technology etc. The system design and acquisition data of the large-scale system must be the subject under strict configuration control and management. Systems engineering technology development project for Korea next generation High-speed Electric Multiple Unit (HEMU) system in progress is a national large system development project that is not only a large-size and complex but also multi-disciplinary in nature. Therefore, all stakeholders must understand and share the functional and performance requirements of HEMU throughout its life-cycle phases. Also in the test and evaluation phase, all systems requirements must be verified. In 2011, the prototype train manufacturing will be completed. It will do test run on the commercial line and all systems requirements are verified until 2012. For the system verification, the test and evaluation process have to be established before the test trial run. Using a systems engineering tool, the system design database(SDD) with requirements traceability and development process management in the course of the development have to be established. This paper represents the test and evaluation process development based on the SEMP(Systems Engineering Management Plan) developed in the design stage. The test and evaluation process is refined and updated in comparison to the design stage one. The test and evaluation process consists of procedure, test and evaluation method and schedule. So through this process, it is defined that each systems requirements is verified on which test and about what time.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.1
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• pp.255-259
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• 2016

Background: Reliable and validated instruments are needed in order to study the quality of life in myeloma patients. This study aimed to translate and explore the psychometric properties of the European Organisation for Research and Treatment of Cancer (EORTC) myeloma module (QLQ-MY20) in Iranian patients. Materials and Methods: Two hundred and fifteen patients with multiple myeloma (MM) were recruited from Imam Khomeini Hospital, Tehran. A standard forward-backward translation procedure was implemented. Participating patients were asked to complete the EORTC QLQ-C30 and the QLQ-MY20 three times, at study entry, after two weeks, and again after three months. Data were tested for the range of measurement, internal consistency, test-retest reliability, known group comparison, responsiveness and factor structure. Results: Mean age of the patients was 60.7 years. No floor and ceiling effects were seen for the QLQ-MY20. Cronbach's ${\alpha}$ was greater than 0.80 for all three multi-item scales (ranging from 0.82 to 0.93). All four scales had test-retest reliability of 0.85 or greater. Results of the confirmatory factor analysis that the hypothesized 3-scale measurement model of the QLQ-MY20. Moreover, the Persian version for the QLQ-MY20 differentiated between subgroups of the patients in terms of beta-2 microglobulin, fracture and performance status. The responsiveness of the QLQ-MY20 to change over time was confirmed within 3 months. Conclusions: the results of our study indicate that our Iranian version of the QLQ-MY20 is a feasible, reliable and valid questionnaire for assessing the condition-specific quality of life of patients with MM.

• Quality Improvement in Health Care
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• v.9 no.2
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• pp.148-163
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• 2002

Background : The personnel of emergency department have been under tremendous pressure to manage unexpected emergency situations and excited patients. And interpersonal conflict has existed always, because emergency department was consisted of various personnel of their own specialty. The patient's satisfaction has to come from the personnel's satisfaction. The purpose of this study was to evaluate emergency department personnel's job satisfaction and its related factors and to improve quality of emergency medical service Methods : A self-administered questionnaire survey to the emergency department personnel was conducted between September 1 and October 31, 2001. The response rate was 90.2%. Using SAS program (Version 6.12), the collected data was analyzed by frequency, ANOVA, multiple comparison, Pearson correlation procedure, and stepwise multiple regression analysis. Result : The analysis of related factors of job satisfaction showed high score of interpersonal interaction (3.246), professional prestige (3.095), autonomy (2.916), task requirements (2.701), organizational requirements (2.444), and pay (1.953) in order of item mean. Professional prestige (0.498), task requirements (0.464), and organizational requirements (0.408) were highly positive correlated with overall level of job satisfaction. The factors influencing the job satisfaction were professional prestige and task requirements which explaining efficacy were 37.6% and 32.2% respectively. The total explaining efficacy was 33.6%. Conclusion : It was found out that emergency department personnel's job satisfaction can be raised by promoting professional prestige and task requirements. The personnel of emergency department have to be satisfied through their job, and the administration of the hospital has to pay more attention to their employees' job satisfaction and it related factors.