• Title/Summary/Keyword: Multidisciplinary engineering

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Present Status and Future of AI-based Drug Discovery (신약개발에서의 AI 기술 활용 현황과 미래)

  • Jung, Myunghee;Kwon, Wonhyun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.25 no.12
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    • pp.1797-1808
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    • 2021
  • Artificial intelligence is considered one of the core technologies leading the 4th industrial revolution. It is adopted in various fields bringing about a huge paradigm shift throughout our society. The field of biotechnology is no exception. It is undergoing innovative development by converging with other disciplines such as computers, electricity, electronics, and so on. In drug discovery and development, big data-based AI technology has a great potential of improving the efficiency and quality of drug development, rapidly advancing to overcome the limitations in the existing drug development process. AI technology is to be specialized and developed for the purpose including clinical efficacy and safety-related end points based on the multidisciplinary knowledge such as biology, chemistry, toxicology, pharmacokinetics, etc. In this paper, we review the current status of AI technology applied for drug discovery and consider its limitations and future direction.

4인승 선미익 경항공기 비행하중 해석

  • Shin, Jeong-Woo;Kim, Tae-Uk;Lee, Sang-Wook;Shim, Jae-Yeul;Hwang, In-Hee
    • Aerospace Engineering and Technology
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    • v.4 no.1
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    • pp.1-8
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    • 2005
  • Civil aviation regulation such as FAR and loads analysis procedure based on this was explained, and loads analysis procedure and results for Smart UAV was presented for application case. For loads analysis, applicable regulations and loads conditions should be prepared in advance, and modeling for aerodynamics, weight, and structure should be performed. Panel method is usually adopted for aircraft loads analysis to obtain aerodynamic loads. In this study, ARGON which is multidisciplinary fixed wing aircraft design software co-developed by KARI and TsAGI was used for loads analysis. ARGON can be utilized for flutter and stress analysis as well as for flight and ground loads analysis. In this paper, flight loads analysis of 4-seater canard airplane was performed with ARGON and that results were presented.

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Prediction of long-term wind speed and capacity factor using Measure-Correlate-Predict method (측정-상관-예측법을 이용한 장기간 풍속 및 설비이용률의 예측)

  • Ko, Kyung-Nam;Huh, Jong-Chul
    • Journal of the Korean Solar Energy Society
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    • v.32 no.6
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    • pp.37-43
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    • 2012
  • Long-term variations in wind speed and capacity factor(CF) on Seongsan wind farm of Jeju Island, South Korea were derived statistically. The selected areas for this study were Subji, having a year wind data at 30m above ground level, Sinsan, having 30-year wind data at 10m above ground level and Seongsan wind farm, where long-term CF was predicted. The Measure-Correlate-Predict module of WindPRO was used to predict long-tem wind characteristics at Seongsan wind farm. Eachyear's CF was derived from the estimated 30-year time series wind data by running WAsP module. As a result, for the 30-year CFs, Seongsan wind farm was estimated to have 8.3% for the coefficien to fvariation, CV, and-16.5% ~ 13.2% for the range of variation, RV. It was predicted that the annual CF at Seongsan wind farm varied within about ${\pm}4%$.

ABLATION OF PTFE NOZZLE DRIVEN BY ARC PLASMA (아크 플라즈마에 의한 PTFE 노즐 용삭현상)

  • Lee J.C.;Kim Y.J.
    • 한국전산유체공학회:학술대회논문집
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    • 2005.10a
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    • pp.311-317
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    • 2005
  • It has been the most progressive interruption technique to use the ablation gas from the surface of PTFE nozzle driven by arc plasma during switching process in $SF_6$ gas circuit breakers. This advanced interruption technique can reduce the required mechanical energy to compress and blow the gas for extinguishing the arc plasma between the electrodes due to using the ablation effect instead. In order to consider the phenomena during calculation of switching process, it is required to confirm the principles of ablation from PTFE nozzle as well as of arc plasma during switching process. In this study, we have calculated the switching process considered the ablation of PTFE nozzle driven by arc plasma using multidisciplinary simulation technique and compared the results with the data without the ablation effect. More $50\%$ difference of pressure rise inside expansion chamber has been found from the results and it should be indispensable for this type of computational work to consider and include the ablation effect of PTFE nozzle. Further study on turbulence and radiation will be followed.

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Accuracy Assessment of Annual Energy Production Estimated for Seongsan Wind Farm (성산 풍력발전단지의 연간발전량 예측 정확도 평가)

  • Ju, Beom-Cheol;Shin, Dong-Heon;Ko, Kyung-Nam
    • Journal of the Korean Solar Energy Society
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    • v.36 no.2
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    • pp.9-17
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    • 2016
  • In order to examine how accurately the wind farm design software, WindPRO and Meteodyn WT, predict annual energy production (AEP), an investigation was carried out for Seongsan wind farm of Jeju Island. The one-year wind data was measured from wind sensors on met masts of Susan and Sumang which are 2.3 km, and 18 km away from Seongsan wind farm, respectively. MERRA (Modern-Era Retrospective Analysis for Research and Applications) reanalysis data was also analyzed for the same period of time. The real AEP data came from SCADA system of Seongsan wind farm, which was compare with AEP data predicted by WindPRO and Meteodyn WT. As a result, AEP predicted by Meteodyn WT was lower than that by WindPRO. The analysis of using wind data from met masts led to the conclusion that AEP prediction by CFD software, Meteodyn WT, is not always more accurate than that by linear program software, WindPRO. However, when MERRA reanalysis data was used, Meteodyn WT predicted AEP more accurately than WindPRO.

Optimization of Stand-Alone Hybrid Power Systems Using HOMER Program (HOMER 프로그램을 이용한 독립형 하이브리드 발전시스템 최적화)

  • Yang, Su-Hyung;Boo, Chang-Jin;Kim, Ho-Chan
    • Journal of the Korean Solar Energy Society
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    • v.32 no.2
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    • pp.11-18
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    • 2012
  • Diesel fuel is expensive because transportation to remote areas adds extra cost, and it causes air pollution by engine exhaust. Providing a feasible economical and environmental solution to diesel generators is important. A hybrid system of renewable plants and diesel generators can benefit islands or other isolated communities and increase fuel savings. Renewable energy is, however, a natural source that produces a fluctuating power output. In this paper, hybrid power system of the marado lighthouse is proposed to supply stable power in the stand-alone hybrid power system. The proposed hybrid power system consists of the diesel generator, wind turbine, photovoltaic, fuel cell, and battery bank. To decrease the carbon emissions and find the optimization, the cost analysis of hybrid system is simulated using HOMER program and the optimized hybrid power system is designed.

A Study of Institutional Improvement and Its Effects about Practical Use of Community Space in Public Rental Housing Complex (공공임대주택 커뮤니티공간 실용화를 위한 제도개선과 그 효과 고찰)

  • Park, Jung-Eun;Lee, Hyo-Won
    • Journal of the Korean housing association
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    • v.26 no.5
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    • pp.61-70
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    • 2015
  • According to "The regulations regarding the residential construction standards", residents' common spaces are restricted by the standards on building facilities. In a typical apartment complex, residents' communal facilities are represented by a children's playground, a elderly social station, and a management office. However, these residents' communal facilities do not reflect residents' composition characteristics. Multidisciplinary research and experimentation to enable the community of housing complex are being actively conducted. In these situation, we observed institutional improvement about installing standard of community space, and analysed the tendency. The purpose of this study is to propose practical institutions to review the institutional improvement. We conducted a case study where was renovated the community space according to the new standard. As a results, the installing standard of the community space has changed in the direction to increase the autonomy of resident. These results raise the practical performance of the community space, and it has the effect of increasing the satisfaction of the residential environment. The results of this study suggest an alternative to the institutional aspects and planning aspects for community activation in housing complex.

Numerical Study on a Diffused-mode Arc within a Vacuum Interrupter (진공차단부에서 발생하는 확산형 아크 수치해석)

  • Cho, S.H.;Hwang, J.H.;Lee, J.C.;Choi, M.J.;Kwon, J.R.;Kim, Y.J.
    • 한국전산유체공학회:학술대회논문집
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    • 2008.03b
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    • pp.479-482
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    • 2008
  • In order to more closely examine the vacuum arc phenomena, it is necessary to predict the magnetohydrodynamic (MHD) characteristics by the multidisciplinary numerical modeling, which is coupled with the electromagnetic and hydrodynamic fields, simultaneously. In this study, the thermal-fluid characteristics of high current vacuum arcs were calculated by a commercial multiphysics package, ANSYS, in order to obtain Joule heat, Lorentz force and the interactions with flow variables. We assumed the diffused-mode arc within an AMF vacuum interrupter. It was found with four different currents that the temperature distributions on the anode surface are diffused uniformly without concentration in 7kA for both types (cup and coil-type). But the arc plasma transition and an increase of thermal flux density for increasing the applied current have caused the change of temperature distributions on the anode surface. We should need further studies on the two-way coupling method and radiation model for arc plasmas in order to accomplish the advanced analysis method for multiphysics.

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Outline of Domain Theory As a New Approach to Software Reuse (S/W 재사용을 위한 새로운 접근법으로서의 Domain Theory의 개요)

  • Ham, Dong-Han;Kim, Jin-Sam;Ha, Su-Jung;Cho, Jin-Hee
    • 한국IT서비스학회:학술대회논문집
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    • 2002.11a
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    • pp.425-430
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    • 2002
  • Over the years, several different approaches have been proposed to enhance the practice of software reuse. These approaches vary in reuse abstraction levels or application domains they focus on. However, it seems that they do not adequately meet the needs of software designers in planning and managing reuse. One reason may be the lack of conceptually well-established framework supporting work domain analysis and modeling. As a new viable solution to this problem, Sutcliffe and his colleagues developed Domain Theory , which is introduced in this paper. Utilizing multidisciplinary perspective, such as cognitive psychology, management science, human-computer interaction, and software engineering. it provides a schematic framework that defines a comprehensive library of generic and reusable models of domain knowledge in terms of generic tasks and meta-domains. It also provides useful methods and guidelines for software reuse, emphasizing the concept of abstraction process in a designer s mind. This paper firstly gives a brief overview of fundamentals of software reuse. Next, it explains the foundation of domain theory and discusses its applicability to software reuse. In particular, the taxonomy of meta-domains and the types of generic tasks are described in more detail. Finally, the future research framework, which primarily addresses the problem of how to apply the domain theory to various work domains, is proposed.

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Bio-fusion and Medical Device Industry (바이오융합 및 의료기기 산업)

  • Park, Su A;Lee, Jun Hee;Kim, Wan Doo
    • Transactions of the KSME C: Technology and Education
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    • v.5 no.1
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    • pp.23-52
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    • 2017
  • Bio-fusion and medical device industry is the multidisciplinary engineering application technology industries, which are fused, such as electricity, electronics, machinery, materials. It aims to improve the quality of human life by using bio-fusion and medical devices, and is an important industry recognition and brand power for the product. However, there is a period that is required from the development of products with technology-dependent industries. Therefore, it is necessary to have continuous effort for industrial investment in research and development at the national level including technical support, institutional support, and human resources.