• Title/Summary/Keyword: Multi-version Structure

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Weighted zero-inflated Poisson mixed model with an application to Medicaid utilization data

  • Lee, Sang Mee;Karrison, Theodore;Nocon, Robert S.;Huang, Elbert
    • Communications for Statistical Applications and Methods
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    • v.25 no.2
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    • pp.173-184
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    • 2018
  • In medical or public health research, it is common to encounter clustered or longitudinal count data that exhibit excess zeros. For example, health care utilization data often have a multi-modal distribution with excess zeroes as well as a multilevel structure where patients are nested within physicians and hospitals. To analyze this type of data, zero-inflated count models with mixed effects have been developed where a count response variable is assumed to be distributed as a mixture of a Poisson or negative binomial and a distribution with a point mass of zeros that include random effects. However, no study has considered a situation where data are also censored due to the finite nature of the observation period or follow-up. In this paper, we present a weighted version of zero-inflated Poisson model with random effects accounting for variable individual follow-up times. We suggested two different types of weight function. The performance of the proposed model is evaluated and compared to a standard zero-inflated mixed model through simulation studies. This approach is then applied to Medicaid data analysis.

De-novo Hybrid Protein Design for Biodegradation of Organophosphate Pesticides

  • Awasthi, Garima;Yadav, Ruchi;Srivastava, Prachi
    • Microbiology and Biotechnology Letters
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    • v.47 no.2
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    • pp.278-288
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    • 2019
  • In the present investigation, we attempted to design a protocol to develop a hybrid protein with better bioremediation capacity. Using in silico approaches, a Hybrid Open Reading Frame (Hybrid ORF) is developed targeting the genes of microorganisms known for degradation of organophosphates. Out of 21 genes identified through BLAST search, 8 structurally similar genes (opdA, opd, opaA, pte RO, pdeA, parC, mpd and phnE) involved in biodegradation were screened. Gene conservational analysis categorizes these organophosphates degrading 8 genes into 4 super families i.e., Metallo-dependent hydrolases, Lactamase B, MPP and TM_PBP2 superfamily. Hybrid protein structure was modeled using multi-template homology modeling (3S07_A; 99%, 1P9E_A; 98%, 2ZO9_B; 33%, 2DXL_A; 33%) by $Schr{\ddot{o}}dinger$ software suit version 10.4.018. Structural verification of protein models was done using Ramachandran plot, it was showing 96.0% residue in the favored region, which was verified using RAMPAGE. The phosphotriesterase protein was showing the highest structural similarity with hybrid protein having raw score 984. The 5 binding sites of hybrid protein were identified through binding site prediction. The docking study shows that hybrid protein potentially interacts with 10 different organophosphates. The study results indicate that the hybrid protein designed has the capability of degrading a wide range of organophosphate compounds.

A 2-Dimension Torus-based Genetic Algorithm for Multi-disk Data Allocation (2차원 토러스 기반 다중 디스크 데이터 배치 병렬 유전자 알고리즘)

  • 안대영;이상화;송해상
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.41 no.2
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    • pp.9-22
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    • 2004
  • This paper presents a parallel genetic algorithm for the Multi-disk data allocation problem an NP-complete problem. This problem is to find a method to distribute a Binary Cartesian Product File on disk-arrays to maximize parallel disk I/O accesses. A Sequential Genetic Algorithm(SGA), DAGA, has been proposed and showed the superiority to the other proposed methods, but it has been observed that DAGA consumes considerably lengthy simulation time. In this paper, a parallel version of DAGA(ParaDAGA) is proposed. The ParaDAGA is a 2-dimension torus-based Parallel Genetic Algorithm(PGA) and it is based on a distributed population structure. The ParaDAGA has been implemented on the parallel computer simulated on a single processor platform. Through the simulation, we study the impact of varying ParaDAGA parameters and compare the quality of solution derived by ParaDAGA and DAGA. Comparing the quality of solutions, ParaDAGA is superior to DAGA in all cases of configurations in less simulation time.

Case Study for Ship Ad-hoc Networks under a Maritime Channel Model in Coastline Areas

  • Su, Xin;Yu, HaiFeng;Chang, KyungHi;Kim, Seung-Geun;Lim, Yong-Kon
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.10
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    • pp.4002-4014
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    • 2015
  • ITU-R M.1842-1, as a well-known specification dedicated to maritime mobile applications, has standardized wireless transmission protocols according to the particular characteristics of a maritime communications scenario. A time division multiple access (TDMA) frame structure, along with modulation schemes to achieve a high data rate, has been described clearly in ITU-R M.1842-1. However, several specification items are still under "to be decided" status, which brings ambiguity to research works. In addition, the current version of ITU-R M.1842-1 is focused mainly on maritime transmissions in open-sea areas, where the cyclic prefix (CP) is set to zero and only 16-QAM is used in the multi-carrier (MC) system. System performance might be dramatically degraded in coastline areas due to the inter-symbol interference (ISI) caused by selective fading. This is because there is a higher probability that the signal will be reflected by obstacles in coastline areas. In this paper, we introduce the transmission resource block (TRB) dedicated to ITU-R M.1842-1 for a ship ad-hoc network (SANET), where the pilot pattern of TRB is based on the terrestrial trunked radio (TETRA). After that, we evaluated SANET performance under the maritime channel model in a coastline area. In order to avoid noise amplification and to overcome the ISI caused by selective fading, several strategies are suggested and compared in the channel estimation and equalization procedures, where the link-level simulation results finally validate our proposals.

Optimization of Yonsei Single-Photon Emission Computed Tomography (YSECT) Detector for Fast Inspection of Spent Nuclear Fuel in Water Storage

  • Hyung-Joo Choi;Hyojun Park;Bo-Wi Cheon;Kyunghoon Cho;Hakjae Lee;Yong Hyun Chung;Yeon Soo Yeom;Sei Hwan You;Hyun Joon Choi;Chul Hee Min
    • Journal of Radiation Protection and Research
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    • v.49 no.1
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    • pp.29-39
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    • 2024
  • Background: The gamma emission tomography (GET) device has been reported a reliable technique to inspect partial defects within spent nuclear fuel (SNF) of pin-by-pin level. However, the existing GET devices have low accuracy owing to the high attenuation and scatter probability for SNF inspection condition. The purpose of this study is to design and optimize a Yonsei single-photon emission computed tomography version 2 (YSECT.v.2) for fast inspection of SNF in water storage by acquisition of high-quality tomographic images. Materials and Methods: Using Geant4 (Geant4 Collaboration) and DETECT-2000 (Glenn F. Knoll et al.) Monte Carlo simulation, the geometrical structure of the proposed device was determined and its performance was evaluated for the 137Cs source in water. In a Geant4-based assessment, proposed device was compared with the International Atomic Energy Agency (IAEA)-authenticated device for the quality of tomographic images obtained for 12 fuel sources in a 14 × 14 Westinghouse-type fuel assembly. Results and Discussion: According to the results, the length, slit width, and septal width of the collimator were determined to be 65, 2.1, and 1.5 mm, respectively, and the material and length of the trapezoidal-shaped scintillator were determined to be gadolinium aluminum gallium garnet and 45 mm, respectively. Based on the results of performance comparison between the YSECT.v.2 and IAEA's device, the proposed device showed 200 times higher performance in gamma-detection sensitivity and similar source discrimination probability. Conclusion: In this study, we optimally designed the GET device for improving the SNF inspection accuracy and evaluated its performance. Our results show that the YSECT.v.2 device could be employed for SNF inspection.

An Improvement of Stochastic Feature Extraction for Robust Speech Recognition (강인한 음성인식을 위한 통계적 특징벡터 추출방법의 개선)

  • 김회린;고진석
    • The Journal of the Acoustical Society of Korea
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    • v.23 no.2
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    • pp.180-186
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    • 2004
  • The presence of noise in speech signals degrades the performance of recognition systems in which there are mismatches between the training and test environments. To make a speech recognizer robust, it is necessary to compensate these mismatches. In this paper, we studied about an improvement of stochastic feature extraction based on band-SNR for robust speech recognition. At first, we proposed a modified version of the multi-band spectral subtraction (MSS) method which adjusts the subtraction level of noise spectrum according to band-SNR. In the proposed method referred as M-MSS, a noise normalization factor was newly introduced to finely control the over-estimation factor depending on the band-SNR. Also, we modified the architecture of the stochastic feature extraction (SFE) method. We could get a better performance when the spectral subtraction was applied in the power spectrum domain than in the mel-scale domain. This method is denoted as M-SFE. Last, we applied the M-MSS method to the modified stochastic feature extraction structure, which is denoted as the MMSS-MSFE method. The proposed methods were evaluated on isolated word recognition under various noise environments. The average error rates of the M-MSS, M-SFE, and MMSS-MSFE methods over the ordinary spectral subtraction (SS) method were reduced by 18.6%, 15.1%, and 33.9%, respectively. From these results, we can conclude that the proposed methods provide good candidates for robust feature extraction in the noisy speech recognition.

Cinematic Circulation of Meta-verse and Meta-physics (메타버스와 메타피직스의 영화적 순환)

  • Shim, Kwang-hyun
    • Trans-
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    • v.12
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    • pp.81-106
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    • 2022
  • The possibility of metaverse system to be a catalyst for hyper-connected society will be dependent on the speed of connected technological development and its social utilization in the same manner as AI technology. Putting these technical realization processes in brackets, this paper focus on some philosophical-political issues in connection with cognitive-ecological changes in the future cinema which will be influenced by the complexive techno-socio couples of accelerated development of metaverse system. Generally speaking, essence of metaverse system seems to be the degree of immersion by technical accuracy, but is not true. In perspective of cognitive-ecology, flow degree of a picture or photograph is relied not on 'accuracy of representation' but on its message's contextual link-up. In this aspect, real potentiality of metaverse system shall be understood in the context of cognitive-ecological changes of human brain's multi-intelligence networking abilities(intersection of augmentation-simulation and outside-inside) which will be activated in the new structure of natural-social-technological coupling of metaverse system. These cognitive-ecological potentialities have been partially actualized in the cinematic process of tripod mimesis for the longest time, [real contradiction/conflicts (Mimesis-1) -->fictional solutions of cinema (Mimesis-2) --> selective interpretation of spectator's wish fulfillment (Mimesis-3) --> real change (Mimesis-1')]. Therefore metaverse's real potentiality must be considered to be dependent on the possibility of deepening and extending of cinematic circulation between real seperation/problems and ideal connection/solutions. In this context, advanced metaverse system can be compared as a modern technical version of ideal circulation of physics and metaphysics

A Study of 'Families' as presented during the Technology-Home Economics Subject in Middle School: Focusing on the 'The Changing Family' of the 2007 Revised Curriculum (중학교 기술.가정 교과서에 나타난 '가족'에 관한 연구 - 2007 개정 교육과정의 '변화하는 가족' 단원을 중심으로 -)

  • Jun, Mi-Kyung
    • Journal of Korean Home Economics Education Association
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    • v.24 no.2
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    • pp.29-49
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    • 2012
  • The purpose of this study is to look at families as presented on the technology-home economics subject of middle school. To do this, I analyzed the 2007 revised curriculum of the technology-home economics subject, 'Changing Families,' in 11 technology-home economics textbooks (8th grade). The findings are as follows. First, family-related chapters are expanded compared with the previous curriculum in the 2007 revised curriculum. In addition, the new version emphasizes understanding and acceptance of change in families to improve the family life of adolescents. Second, in the 11 types of technology-home economics textbooks, the focusing was on the meaning of the family, the family structure, the function of the family, family roles and family values. There were also no major differences in the aspect of development. Third, in the technology-home economics textbooks, the family was defined as the 'basic group of society', 'a group composed by blood relationships, marriage and adoption', 'an affective group' and 'cohabiting group'. At the same time, there were many cases in which the description of the family was overly romanticized. Such a description of the family does not match the individual family experience of an adolescent. Fourth, all of textbooks dealt with the diversity of the family structure, such as single-parent families, remarriages families, and multi-cultural families. However, the structural characteristics and problems with these types of families are excessively emphasized, which can result in students having stereotypical images of specific family types. Fifth, the explanation of the function of the family was similar among textbooks. The importance of intergenerational cooperation and gender equality was also emphasized. However, such a concept is not considered as proper in a modern society. Thus, the description of a family based on the nuclear family should be sublated. In addition, the explanation of families overall should be developed in such a way that adolescents can interpret their own family experience rather than as an enlightening declaration of the family which disregards the dynamic relationships individual families actually experience.

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