• 대한물리치료과학회지
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• 제9권2호
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• pp.133-141
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• 2002

This purpose of this study was to design the effect of recovering of a hand amputees by Myoelectronic hand. It was designed with 2 degree of freedom in the laboratory. Myoelectronic hand had only one degree of freedom and one movement until now. Also this myoelectronic hand had multi-joint and it could move widely. Wire was used in transmission. Myoelectronic hand data was obtained by analyzing hand anatomically and measuring and that data was applied when it was designed. PID controller of Myoelectronic hand was used to it. Displacement control was applied the first link. Experiment was accomplished in Tip grasp, Power grasp and Hook grasp modes. Displacement control was good in low frequency. Velocity control was applied to each mode. The objective of the study was to develop more better multifunction myoelectronic control strategies. A myoelectronic hand with a hand amputees could do some jobs such as grasping materials, lifting weighting, holding cup and etc. As a result of this study, all subjects with hand amputees significantly improved in ADL. Further studies were needed to evaluate the effect of a myoelectronic hand with more precise laboratory equipment.

• 대한물리치료과학회지
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• 제7권2호
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• pp.475-482
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• 2000

The purpose of this study was to investigate the difference of body composition between male elder and female elder. This study consisted of elder male(n=48) and elder female(n=90). The average age of elder male and female was 73.81, 71.38 years. The data were analyzed with t-test, using SPSS PC+ program. Body composition was measured using Inbody 2.0(seoul, korea) of segmental multi-frequn-cy impedance analyzer technique. The result of this study were the following: 1. The difference of Body composition 1) The muscle mass(kg) of elder male was significantly(P<.00) higher than elder female by 8.30kg. 2) The %fat of elder female was significantly(P<.00) higher than elder male by 8.65%. 3) The WHR(%) elder female was no significantly higher than elder male by 0.01%. 4) The free fat mass(kg) of elder male was significantly(P<.00) higher than elder female by 8.67kg. 5) The TBW(l) of elder male was significantly(P<.00) higher than elder female by 6.081 The factor of significant difference of between elder male and female was muscle mass(kg), %fat, free fat mass(kg), total body water(l).

• 한국멀티미디어학회논문지
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• 제20권2호
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• pp.115-125
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• 2017

For many stroke patients undergoing rehabilitation therapy, there is a need for indicator for evaluating the body function in paretic and non-paretic regions of stroke patients quantitatively. In this paper, the function of muscles and cells in paretic and non-paretic regions of severe and mild hemiplegic stroke patients was evaluated using multi-channel bioelectrical impedance spectroscopy. The paretic and non-paretic regions of severe and mild stroke patients were quantitatively assessed by using bioelectrical impedance parameters such as prediction marker (PM), phase angle (${\theta}$), characteristic frequency ($f_c$), and bioelectrical impedance vector analysis (BIVA). The mean values of impedance vector were significantly discriminated in all comparisons (severe-paretic, severe-non-paretic, mild-paretic, and mild-non-paretic). The bioelectrical impedance parameters were proved to be a very valuable tool for quantitatively evaluating the paretic and non-paretic regions of hemiplegic stroke patients.

• 한국학교보건학회지
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• 제25권1호
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• pp.114-121
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• 2012

Purpose: The purpose of this study was to investigate the concentrations of volatile organic compounds at elementary, middle, and high schools in Ulsan and its surroundings. Methods: To assess the hazardous chemicals of the 66 classrooms in the 22 schools, the 6 volatile organic compounds such as TVOCs (Total Volatile Organic Compounds), benzene, toluene, xylene, ethyl benzene and stylene were measured and analyzed from the beginning of May to the end of December, 2009. Results: The mean concentrations of TVOCs in the elementary schools were higher than those of middle and high schools, and multi-purpose classrooms was higher than that in general ones. The benzene and toluene level in schools in Dong-Gu in the vicinity of assorted industrial complexes was higher than that of schools located in other districts around the Ulsan Metropolitan Area. Conclusion: In case of schools in Ulsan Metropolitan Area, elementary school, schools in Dong-Gu, and multipurpose classrooms over general classrooms should be given a high priority for the management of volatile organic compounds.

• PNF and Movement
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• 제16권1호
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• pp.125-132
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• 2018

Purpose: The aim of this study was to investigate the isolated activation ratio of the quadriceps femoris muscle on different support surfaces during squat exercise. Methods: Twenty participants (10 males and 10 females) voluntarily agreed to participate in the research after receiving an explanation about the purpose and process of the study. Each participant performed squat exercises on three different support surfaces (a flat surface, a form roller, and an unstable surface). Muscle activities of the rectus femoris (RF), vastus medialis (VM), and vastus lateralis (VL) were measured by electromyography. The isolated activation ratio of the quadriceps femoris muscle was calculated using the %isolation formula. Results: For the squat exercise, the %isolation value of the VM was significantly higher on the unstable surface than on the flat surface and form roller. In contrast, the %isolation values for the RF for the squat exercise were significantly higher on the flat surface and form roller than on the unstable surface. There was no significant differences in the %isolation values of the VL on the three different surfaces. Conclusion: The findings indicate that squat exercise on different surfaces results in differential activation of the quadriceps femoris muscle, which suggests that squat exercise on a multi-directional unstable surface could increase the isolated activation ratio of the VM.

• Bulletin of the Korean Chemical Society
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• 제30권5호
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• pp.1101-1106
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• 2009

Multivalent and multi-specific antibodies can provide valuable tools for bio-medical research, diagnosis and therapy. In antigen-antibody interactions, the avidity of antibodies depends on the affinity and the number of binding sites.$^1$ As artificial multivalent antibody agents, single chain Fv-streptavidin fusion tetramer proteins $(scFv-SA)_4$ have been previously tested.$^{1,\;2}$ Although, the Fab domain is known to be more stable than scFv in animal models,$^{3,\;4}$ it has never been used to make a multivalent agent with a streptavidin fusion. In this study, we prepared tetra-valent $(Fab-cSA)_4$ by fusing Fab with core streptavidin (cSA). This molecule was made using inclusion body production, refolding and chromatography purification. Affinities of the Fab-cSA tetramer and a scFv-cSA tetramer to a cell surface antigen were compared by ELISA using biotin-HRP. The Fab-cSA tetramer showed higher binding avidity than the scFv-cSA tetramer. The higher binding avidity of the Fab-cSA tetramer demonstrates its potential as a therapeutic agent for target-specific antibody therapy.

• Journal of Dental Anesthesia and Pain Medicine
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• 제19권3호
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• pp.159-165
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• 2019

Background: Dental procedures commonly involve the injection of local anesthetic agents, which causes apprehension in patients. The objective of dental practice is to provide painless treatment to the patient. The purpose of this study was to evaluate the effect of Low Level Laser Therapy (LLLT) in reducing the pain due to local anesthetic injection. Materials and Methods: A prospective, split-mouth study was conducted on 25 patients. In Condition A, LLLT was administered followed by the administration of a standard local anesthetic agent. Patients' perception of pain with use of LLLT was assessed based on a Visual Analogue Scale (VAS). In Condition B, LLLT was directed to the mucosa but not activated, followed by the administration of local anesthesia. VAS was used to assess the pain level without the use of LLLT. Results: Comparison between Condition A and Condition B was done. A P value < 0.001 was considered significant, indicating a definite statistical difference between the two conditions. Conclusion: In our study, we observed that LLLT reduced pain during injection of local anesthesia. Further multi-centric studies with a larger sample size and various modifications in the study design are required.

• 대한물리의학회지
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• 제14권1호
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• pp.111-119
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• 2019

PURPOSE: The aim of this study was to determine how biofeedback training with Shaker exercise effects the activation of the cervical myocardial muscle in stroke with swallowing disorder. METHODS: From June 2018 to September 2018, 30 patients who were hospitalized at C hospital and K hospital in Daegu, and K hospital in Gumi were surveyed to meet the criteria for selection. The participants were classified into three groups, and Shaker exercise was applied three times a day, five times a week, for four weeks; visuoauditory biofeedback group (VABG), visual biofeedback group (VBG), and self-exercises group (SG). In addition, the suprahyoid muscle activity was performed three times (before intervention, after intervention, and after two weeks). RESULTS: The pre and post-test comparisons, revealed a significant difference between the three groups (p<.01); VABG had the highest suprahyoid muscle activity. The post-test and follow-up test produced similar results in, the three groups (p>.05). The mean comparison showed the smallest difference in VABG, indicating that muscle persistence was the best. CONCLUSION: Shaker exercise has an effect on suprahyoid muscle activation. Biofeedback training, which provides an input of multi-sensory information in swallowing disorder treatment is recommended because it has the greatest effect when combined with visuoauditory biofeedback.

• 인간행동과 음악연구
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• 제7권1호
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• pp.1-15
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• 2010

본 연구는 지적장애영유아의 수학개념 발달을 위한 음악활동의 이론적 배경을 고찰하는 데에 그 목적이 있다. 음악은 청각, 시각, 촉각을 자극할 수 있는 다감각적 매체로써 다양한 경로를 통해 인지능력을 향상 할 수 있는 방법을 제공할 수 있고, 영유아의 집중을 유도할 수 있는 요소를 가지고 있으며, 학습에 필요한 기본적 정보를 기억하는 것을 돕는 보조적 역할 및 동기부여의 도구로 사용될 수 있으므로, 지적장애영유아 치료 교육현장에서 효과적으로 사용될 수 있다. 음악의 각 요소들과 특성들을 파악하는 것은 수학개념 발달에 사용될 수 있는 음악활동의 종류에 대한 이론적 배경을 제공하며, 적절한 음악활동을 구성할 수 있는 방향을 제시할 수 있는 기초를 마련한다. 본 연구는 지적장애영유아 수학교육의 현장에서 음악활동이 적극적으로 활용되어야 한다는 필요성을 제시하며, 수학개념 발달을 위한 다양한 음악활동 개발의 필요성을 논의하였다.

• 대한임상독성학회지
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• 제13권2호
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• pp.103-110
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• 2015

Purpose: The purpose of this study is to evaluate the effectiveness and the adverse events of high dose insulin/euglycemia therapy in acute calcium channel blocker (CCB) poisoning. Methods: We developed a systematic search strategy and applied it to 4 electronic reference databases. We searched medical journals as well as the bibliographies of relevant articles. All forms of literature relevant to human use of high dose insulin for acute CCB poisoning were included. The literature search was conducted by two investigators in August, 2015 with publication language restricted to English and Korean. Case reports were divided between CCB overdose alone and multi-drug overdose including CCB. The effect and adverse event of high dose insulin and clinical outcome of each case were analyzed. Results: Among 55 searched studies, 20 studies were included. A prospective study, a retrospective study, a systematic review study, and 17 case reports were identified. Case reports consisted of 11 CCB alone and 12 multidrug overdose cases including CCB. Although most cases described significant clinical improvements, one of them showed no beneficial effect. Several adverse events including hypoglycemia and hypokalemia were reported. No significant sequalae from adverse events was reported. Conclusion: Although there were many case reports demonstrating successful use of high dose insulin for CCB poisoning, the effect cannot be estimated due to a possibility of publication bias. Therefore, high dose insulin/euglycemia therapy might be considered adjunctive therapy in cases of CCB intoxication refractory for standard therapy.