• The Journal of Korean Institute of Communications and Information Sciences
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• v.41 no.12
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• pp.1715-1720
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• 2016

In the upcoming 5-generation mobile communication system, various techniques for improving the power efficiency and spectral efficiency have been proposed. 5G mobile communication system also have been studied a lot of multi-carrier-based modulation techniques like the 4G mobile communication system. In this paper, we analyzed the conventional system structure of the Zero-tail DFT-s-OFDM and UW (Unique Word) -DFT-s-OFDM system based on DFT-s-OFDM system in these techniques. UW and zero are added and used each system, and CP is removed. the result of quality of systems for simulation, OOB(Out of Band) power of Zero-tail DFT-s-OFDM and UW-DFT-s-OFDM use the less time resource as long as CP length, also both systems are reduced about 11dB than DFT-s-OFDM system. In these result, Zero-tail DFT-s-OFDM and UW-DFT-s-OFDM system are more effective than DFT-s-OFDM system.

• The Korean Journal of Physiology and Pharmacology
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• v.24 no.4
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• pp.299-310
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• 2020

Alzheimer's disease (AD) is a multi-faceted neurodegenerative disease. Thus, current therapeutic strategies require multitarget-drug combinations to treat or prevent the disease. At the present time, single drugs have proven to be inadequate in terms of addressing the multifactorial pathology of AD, and multitarget-directed drug design has not been successful. Based on these points of views, it is judged that combinatorial drug therapies that target several pathogenic factors may offer more attractive therapeutic options. Thus, we explored that the combination therapy with lower doses of cilostazol and aripiprazole with add-on donepezil (CAD) might have potential in the pathogenesis of AD. In the present study, we found the superior efficacies of donepezil add-on with combinatorial mixture of cilostazol plus aripiprazole in modulation of expression of AD-relevant genes: Aβ accumulation, GSK-3β, P300, acetylated tau, phosphorylated-tau levels, and activation of α-secretase/ADAM 10 through SIRT1 activation in the N2a Swe cells expressing human APP Swedish mutation (N2a Swe cells). We also assessed that CAD synergistically raised acetylcholine release and choline acetyltransferase (CHAT) expression that were declined by increased β-amyloid level in the activated N2a Swe cells. Consequently, CAD treatment synergistically increased neurite elongation and improved cell viability through activations of PI3K, BDNF, β-catenin and α7-nicotinic cholinergic receptors in neuronal cells in the presence of Aβ_1-42. This work endorses the possibility for efficient treatment of AD by supporting the synergistic therapeutic potential of donepezil add-on therapy in combination with lower doses of cilostazol and aripiprazole.

• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.314-314
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• 2012

The dilute magnetic semiconductors (DMS) have been developed to multi-functional electro-magnetic devices. Specially, the Si based DMS formed by ion implantation have strong advantages to improve magnetic properties because of the controllable effects of carrier concentration on ferromagnetism. In this study, we investigated the deep level states of Fe- and Co-ions implanted Si wafer during rapid thermal annealing (RTA) process. The p-type Si (100) wafers with hole concentration of $1{\times}10^{16}cm^{-3}$ were uniformly implanted by Fe and Co ions at a dose of $1{\times}10^{16}cm^{-2}$ with an energy of 60 keV. After RTA process at temperature ranges of $500{\sim}900^{\circ}C$ for 5 min in nitrogen ambient, the Au electrodes with thickness of 100 nm were deposited to fabricate a Schottky contact by thermal evaporator. The surface morphology, the crystal structure, and the defect state for Fe- and Co- ion implanted p-type Si wafers were investigated by an atomic force microscopy, a x-ray diffraction, and a deep level transient spectroscopy, respectively. Finally, we will discuss the physical relationship between the electrical properties and the variation of defect states for Fe- and Co-ions implanted Si wafer after RTA.

• Proceedings of the Korean Information Science Society Conference
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• 2006.10d
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• pp.263-267
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• 2006

OFDM(A) 기반 네트워크는 IEEE 802.16e 시스템 및 WiBro 시스템 등으로 구현되고 있으며, 4G 시스템과 같은 차세대 이동통신 시스템의 기반 기술로서 많이 연구되고 있는 시스템이다. 이와 같은 OFDM(A) 시스템을 기반으로 IP 네트워크를 구축하게 된다면, 단말의 핸드오버를 지원하기 위하여 MAC 및 IP 계층에서의 핸드오버 기법에 대한 정의가 필요하다. IP 네트워크의 가장 큰 특징은 CDMA와 같은 서킷 네트워크가 아니라 패킷 네트워크라는 것이다. 이러한 패킷기반 네트워크에서의 소프트 핸드오버 기법은 CDMA 네트워크에서 제공되고 있는 소프트 핸드오버 기법을 그대로 적용할 수 없다. CDMA 소프트 핸드오버 기법은 물리계층에서의 신호 결합을 수행하게 되는데 패킷 네트워크에서 두 기지국으로부터 전송되는 패킷은 MAC 및 IP 헤더를 가지게 되고, 헤더에 포함되는 정보는 각 기지국에서 서로 다르게 전송하므로 물리계층에서의 신호 결합을 수행할 수가 없다. 본 논문에서는 기존에 제안된 소프트 핸드오버 기법의 단점을 보완하고 IP 기반 네트워크에 적용 가능한 소프트 핸드오버 기법을 제안한다. 제안하는 소프트 핸드오버 기법은 패킷 네트워크의 특성을 반영하여 소프트 핸드오버에 참여하는 기지국이 서로 다른 패킷을 전송하도록 디자인하였고, 에러 발생률을 낮추기 위하여 AMC (Adaptive Modulation and Coding) 기법을 적용하였다. 또한 OFDM(A) 시스템의 multi-carrier 특성을 이용하여 네트워크 자원을 효율적으로 사용함으로써 네트워크의 전체적인 성능 향상이 가능하도록 개발되었다.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.8 no.4
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• pp.342-353
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• 1997

This paper presents an analytical evaluation of a hybrid direct-sequence/slow frequencyhopped code division multiple-access (DS/SFH-CDMA) system employing noncoherent M-ary frequency shift keying(MFSK) modulation in a multiple Nakagami fading (m) environment. Multipath interference (MPI) and multi-access interference (MAI) is taken into account and the spectral efficiency is calculated for uncoded as well as channel coding systems. Predetection multipath maximal ratio combining (MRC) diversity in conjunction with interleaved channel coding (Hamming(7,4) code, BCH(15, 7) code and RS (7, 4), (15, 9)) code ) is employed for improving the bit error rate (BER) performance. The BER of noncoherent hybrid system is obtained using a Gaussian interference approximation.

• Journal of Digital Convergence
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• v.12 no.11
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• pp.407-414
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• 2014

The aim of the present study was to carry out quantitative analysis of spatial resolution for the influence of the focus size and digital image post-processing on the Computed Radiography (CR). The modulation transfer functions of an edge measuring method (MTF) was used for the evaluation of the spatial resolution. The focus size of X-ray tube was used the small focus (0.6 mm) and the large focus (1.2 mm). We evaluated the 50% and 10% of MTF for the enhancement of edge and contrast by using multi-scale image contrast amplification (MUSICA) in digital image post-processing. As a results, the edge enhancement than the contrast enhancement were significantly higher the spatial resolution of MTF 50% in all focus. Also the spatial resolution of the obtained images in a large focus were improved by digital image processing. In conclusion, the results of this study should serve as a basic data for obtain the high resolution clinical images, such as skeletal and chest images on the CR.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38B no.6
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• pp.427-434
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• 2013

In this paper, the design and layout of a 2.5 Gbps arrayed VCSEL driver for optical transceiver having arrayed multi-channel of integrating module is confirmed. In this paper, a 4 channel 2.5 Gbps VCSEL (vertical cavity surface emitting laser) driver array with automatic optical power control is implemented using $0.18{\mu}m$ CMOS process technology that drives a $1550{\mu}m$ high speed VCSEL used in optical transceiver. To enhance the bandwidth of the optical transmitter, active feedback amplifier with negative capacitance compensation is exploited. We report a distinct improvement in bandwidth, voltage gain and operation stability at 2.5Gbps data rate in comparison with existing topology. The 4-CH chip consumes only 140 mW of DC power at a single 1.8V supply under the maximum modulation and bias currents, and occupies the die area of $850{\mu}m{\times}1,690{\mu}m$ excluding bonding pads.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.48 no.11
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• pp.9-16
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• 2011

We need to establish standard for the ICT based on train control system. In order to solve the ISI problem, this paper evaluate the performance of OFDM and FDE system. We seem that OFDM system is better than FDE system. In order to solve ISI problem, SC System is needed a equalizer. And another method is OFDM System. If system is used SC with a equalizer, It is better than OFDM in terms of PAPR, but this system is not easy to use Multi-Antenna technique, i.e., beam-forming and MIMO-multiplexing. And If system is used high-order modulation, BER performance is worse than OFDM. If we think about in terms of PAPR problem, considerations are considered not significant because the size of relays is not considered in the communication between trains and ground.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.21 no.9
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• pp.2433-2443
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• 1996

In this paper, a new technique is proposed for obtaining the error probabilities of the VSB(vestigial sideband modulation) signal in the presence of the cochannel interference and frequency-selective fading channel. For the receivers, a suboptimal matched filter receiver and the MLSE(maximum likelihood sequence estimation) receiver, which is known to be optimal on the fading channel, are considered. First, for the matched filter receiver, the distributions of the random variables, which determine the SER(symbol error rate) are obtained by decomposing the multi-path fading channel into Rayleigh distributed main path and Gaussian distributed remained path channels. the random variables mean the energy of the main path and subpath respecitively, and SER can be calculated from the distribution of them. Next, for the case of the MLSE receover, it is found that the random variables are expressed as a function of integrals. In order to obtain the distribution for the random variables, we expanded each element of integrals with the KL(Karhunen-Loeve) transformation. And it is derived that the distributions for the transformed random variables are given by a sum of chi-square distributions. Finally, we calculated the error rate derived formula on the two-ray fading channel, which is one of widely used models for the frequency-selective fading channel. From the numerical results, it is found that for the matched filer receiver, performance degradation is significant, while the performance degradation at the MLSE receiver is insignificant on the frequency-selective fading channel. However, in case of cochannel interference environment, the error rateis found to increase significantly both at the matched filter and at the MLSE receiver.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.3C
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• pp.209-214
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• 2003

Multi-mode coding method is a reliable DC-suppression method. There are two ways to improve the DC-suppression performance. One is improving scrambler's performance, and the other is improving selection criteria. The latter uses the MRDS(minimum running digital sum) criterion. It is easy to calculate, but its performance goes down when the length of codeword is getting longer. The MSW(mean squared weight) criterion that is known as the best so far regardless of the length of codeword has the high complexity. In this paper, we present the new selection criteria, MPRDS(minimum peak RDS) and A BSRDS(absolute RDS). Their performance are close to the MSW, implementation is simple. And also we present the SC(sign change) that has a subsidiary role with the original selection criteria and improve the capacity.