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Multi-Residue Analysis of 18 Dye Residues in Animal Products by Liquid Chromatography-Tandem Mass Spectrometry

  • Park, Hyunjin;Kim, Joohye;Kang, Hui-Seung;Cho, Byung-Hoon;Oh, Jae-Ho
    • Journal of Food Hygiene and Safety
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    • v.35 no.2
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    • pp.109-117
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    • 2020
  • This study aimed to develop an analytical method for determination of 18 dyes in livestock and fishery products by liquid chromatograph-tandem mass spectrometry (LC-MS/MS). The developed method was validated for linearity, accuracy, limit of quantifications (LOQ) and recovery based on the CODEX guideline (CAC/GL-71). Target matrices (beef, pork, chicken, egg, milk, flatfish, eel, and shrimp) were extracted using acetonitrile (containing 1% of acetic acid) and then, purified with C18 and primary secondary amine (PSA). Calibration linearity was obtained (r2>0.98) and LOQs were 0.002 mg/kg in animal products. The recoveries of dyes were ranged from 63 to 112% and relative standard deviations (RSDs, %) were less than 15%. The residues of 18 dyes were investigated in real samples (n=124) collected from retail markets in South Korea. As a result, a total of seven samples showed positive results for target analytes in fish samples. However, there was no violation according to the maximum residue limits set by the Korean Food Code. The proposed method will be used for routine analysis of dye residues in livestock and fishery products.

A Study on Polynomial Pre-Distortion Technique Using PAPR Reduction Method in the Next Generation Mobile Communication System (차세대 이동통신 시스템에 PAPR 감소기법을 적용한 다항식 사전왜곡 기법에 관한 연구)

  • Kim, Wan-Tae;Park, Ki-Sik;Cho, Sung-Joon
    • Journal of Advanced Navigation Technology
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    • v.14 no.5
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    • pp.684-690
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    • 2010
  • Recently, the NG(Next Generation) system is studied for supporting convergence of various services and multi mode of single terminal. And a demand of user for taking the various services is getting increased, for supporting these services, many systems being able to transmit a large message have been appeared. In the NG system, it has to be supporting the CDMA and WCDMA besides the tele communication systems using OFDM method with single terminal An intergrated system can be improved with adopting of SoC technique. For adopting SoC technique on the intergrated terminal, we have to solve the non linear problem of HPA(High Power Amplifier). Nonlinear characteristic of HPA distorts both amplitude and phase of transmit signal, this distortion cause deep adjacent channel interference. We adopt a polynomial pre-distortion technique for this problem. In this paper, a noble modem design for NG mobile communication service and a method using polynomial pre-distorter with PAPR technique for counterbalancing nonlinear characteristic of the HPA are proposed.

Monitoring of Pesticide Residues and Risk Assessment of Agricultural Products Consumed in South Korea (국내유통농산물 중 잔류농약 모니터링 및 안전성 평가)

  • Kim, Sung-Hun;Choe, Won-Jo;Baik, Yong-Kyoo;Kim, Woo-Seong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.11
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    • pp.1515-1522
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    • 2008
  • Monitoring the pesticide residues in agricultural products is essential to protect consumers, obtain data for risk assessment, and ensure fair trade practices. We developed a multi-residue method for the analysis of 37 pesticides with different physico-chemical properties in agricultural products and analyzed the amount of pesticide residues on about 1,000 samples circulated in South Korea. The samples consisted of 26 different types of agricultural products selected at markets in 14 major cities; cereals (2 species), nuts (1 species) potatoes (1 species), beans (2 species), fruits (3 species), vegetables (16 species), and mushrooms (1 species). In this study, residual pesticides were detected in 23 samples (2.2%) and one sample was detected to be over maximum residue limits (MRLs, 0.1%) for pesticides in foods by the Korea food code. In leafy vegetables such as pepper leaves, radish leaves, cham-na-mul, shin-sun-cho, crown daisy, chwi-na-mul and citrus fruits such as kumquat, 8 kinds of pesticides were detected. Specially, diazinon were detected over MRLs and also, endosulfan, ethoprophos and phenthoate were detected frequently. Based on these results, we investigated the risk assesment from amount of residual pesticide, total %ADI was 1.262%, but the value has not effected on human health.

Run-time Memory Optimization Algorithm for the DDMB Architecture (DDMB 구조에서의 런타임 메모리 최적화 알고리즘)

  • Cho, Jeong-Hun;Paek, Yun-Heung;Kwon, Soo-Hyun
    • The KIPS Transactions:PartA
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    • v.13A no.5 s.102
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    • pp.413-420
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    • 2006
  • Most vendors of digital signal processors (DSPs) support a Harvard architecture, which has two or more memory buses, one for program and one or more for data and allow the processor to access multiple words of data from memory in a single instruction cycle. We already addressed how to efficiently assign data to multi-memory banks in our previous work. This paper reports on our recent attempt to optimize run-time memory. The run-time environment for dual data memory banks (DBMBs) requires two run-time stacks to control activation records located in two memory banks corresponding to calling procedures. However, activation records of two memory banks for a procedure are able to have different size. As a consequence, dual run-time stacks can be unbalanced whenever a procedure is called. This unbalance between two memory banks causes that usage of one memory bank can exceed the extent of on-chip memory area although there is free area in the other memory bank. We attempt balancing dual run-time slacks to enhance efficiently utilization of on-chip memory in this paper. The experimental results have revealed that although our algorithm is relatively quite simple, it still can utilize run-time memories efficiently; thus enabling our compiler to run extremely fast, yet minimizing the usage of un-time memory in the target code.

CNVDAT: A Copy Number Variation Detection and Analysis Tool for Next-generation Sequencing Data (CNVDAT : 차세대 시퀀싱 데이터를 위한 유전체 단위 반복 변이 검출 및 분석 도구)

  • Kang, Inho;Kong, Jinhwa;Shin, JaeMoon;Lee, UnJoo;Yoon, Jeehee
    • Journal of KIISE:Databases
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    • v.41 no.4
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    • pp.249-255
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    • 2014
  • Copy number variations(CNVs) are a recently recognized class of human structural variations and are associated with a variety of human diseases, including cancer. To find important cancer genes, researchers identify novel CNVs in patients with a particular cancer and analyze large amounts of genomic and clinical data. We present a tool called CNVDAT which is able to detect CNVs from NGS data and systematically analyze the genomic and clinical data associated with variations. CNVDAT consists of two modules, CNV Detection Engine and Sequence Analyser. CNV Detection Engine extracts CNVs by using the multi-resolution system of scale-space filtering, enabling the detection of the types and the exact locations of CNVs of all sizes even when the coverage level of read data is low. Sequence Analyser is a user-friendly program to view and compare variation regions between tumor and matched normal samples. It also provides a complete analysis function of refGene and OMIM data and makes it possible to discover CNV-gene-phenotype relationships. CNVDAT source code is freely available from http://dblab.hallym.ac.kr/CNVDAT/.

Investigation of Hydraulic Flow Properties around the Mouths of Deep Intake and Discharge Structures at Nuclear Power Plant by Numerical Model (수치모의를 통한 원자력 발전소 심층 취·배수 구조물 유·출입구 주변에서의 수리학적 흐름특성 고찰)

  • Lee, Sang Hwa;Yi, Sung Myeon;Park, Byong Jun;Lee, Han Seung
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.32 no.2A
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    • pp.123-130
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    • 2012
  • A cooling system is indispensable for the fossil and nuclear power plants which produce electricity by rotating the turbines with hot steam. A cycle of the typical cooling system includes pumping of seawater at the intake pump house, exchange of heat at the condenser, and discharge of hot water to the sea. The cooling type of the nuclear power plants in Korea recently evolves from the conventional surface intake/discharge systems to the submerged intake/discharge systems that minimize effectively an intake temperature rise of the existing plants and that are beneficial to the marine environment by reducing the high temperature region with an intensive dilution due to a high velocity jet and density differential at the mixing zone. It is highly anticipated that the future nuclear power plants in Korea will accommodate the submerged cooling system in credit of supplying the lower temperature water in the summer season. This study investigates the approach flow patterns at the velocity caps and discharge flow patterns from diffusers using the 3-D computational fluid dynamics code of $FLOW-3D^{(R)}$. The approach flow test has been conducted at the velocity caps with and without a cap. The discharge flow from the diffuser was simulated for the single-port diffuser and multi-ports diffuser. The flow characteristics to the velocity cap with a cap demonstrate that fish entrainment can significantly be minimized on account of the low vertical flow component around the cap. The flow pattern around the diffuser is well agreed with the schematic diagram by Jirka and Harleman.

ON THE GALACTIC SPIRAL PATTERNS: STELLAR AND GASEOUS

  • MARTOS MARCO;YANEZ MIGUEL;HERNANDEZ XAVIER;MORENO EDMUNDO;PICHARDO BARBARA
    • Journal of The Korean Astronomical Society
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    • v.37 no.4
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    • pp.199-203
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    • 2004
  • The gas response to a proposed spiral stellar pattern for our Galaxy is presented here as calculated via 2D hydrodynamic calculations utilizing the ZEUS code in the disk plane. The locus is that found by Drimmel (2000) from emission profiles in the K band and at 240 ${\mu}m$. The self-consistency of the stellar spiral pattern was studied in previous work (see Martos et al. 2004). It is a sensitive function of the pattern rotation speed, $\Omega$p, among other parameters which include the mass in the spiral and its pitch angle. Here we further discuss the complex gaseous response found there for plausible values of $\Omega$p in our Galaxy, and argue that its value must be close to $20 km s^{-l}\;kpc^{-1}$ from the strong self-consistency criterion and other recent, independent studies which depend on such parameter. However, other values of $\Omega$p that have been used in the literature are explored to study the gas response to the stellar (K band) 2-armed pattern. For our best fit values, the gaseous response to the 2-armed pattern displayed in the K band is a four-armed pattern with complex features in the interarm regions. This response resembles the optical arms observed in the Milky Way and other galaxies with the smooth underlying two-armed pattern of the old stellar disk populations in our interpretation. The complex gaseous response appears to be related to resonances in stellar orbits. Among them, the 4:1 resonance is paramount for the axisymmetric Galactic model employed, and the set of parameters explored. In the regime seemingly proper to our Galaxy, the spiral forcing appears to be marginally strong in the sense that the 4:1 resonance terminates the stellar pattern, despite its relatively low amplitude. In current work underway, the response for low values of $\Omega$p tends to remove most of the rich structure found for the optimal self-consistent model and the gaseous pattern is ring-like. For higher values than the optimal, more features and a multi-arm structure appears.

Adaptive Migration Path Technique of Mobile Agent Using the Metadata of Naming Agent (네이밍 에이전트의 메타데이터를 이용한 이동 에이전트의 적응적 이주 경로 기법)

  • Kim, Kwang-Jong;Ko, Hyun;Lee, Yon-Sik
    • Journal of the Korea Society of Computer and Information
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    • v.12 no.3
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    • pp.165-175
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    • 2007
  • The mobile agent executes a given task by which the agent code moves to the server directly. Therefore, node migration method becomes an important factor which impact on the whole performance of distributed system. In this paper, we propose an adaptive migration path technique of mobile agent using the metadata of naming agent. In this proposed technique, node selection for migration depends on the content of referenced metadata, and the reliability of migrated information is determined by the metadata updating method and cooperative operations of individual agents in multi-agents system. For these, we design the metadata using by the number of hit documents, hit ratio, node processing time and network delay time, and describe the methods for creating, using and updating metadata for which determine the adaptive node migration path of mobile agent according to the cooperation of individual agents and number of hit documents using by designed metadata. And results of evaluated performance for proposed adaptive migration path technique through the proper experiment and analysis gain rate of high effective information earning, because of high hit ratio(72%) about of fathered documents by case of applying metadata move to the 13 nodes. But, in case of non-applying metadata is hit ratio(46%) of gathered documents and rate of effective information earning about of 26 nodes is 36.8%.

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Numerical Analysis of the Complex Permittivity of MWNT added Epoxy Depending on Agglomeration Size (에폭시 내부의 MWNT 응집 크기에 따른 복소유전율 변화의 해석적 관찰)

  • Shin, Jae-Hwan;Jang, Hong-Kyu;Choi, Won-Ho;Song, Tae-Hoon;Kim, Chun-Gon;Lee, Woo-Yong
    • Composites Research
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    • v.27 no.5
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    • pp.190-195
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    • 2014
  • This paper predicts the complex permittivity of MWNT added epoxy depending on agglomeration by numerical analysis. 1wt% MWNT added epoxy specimen is prepared using 3-roll-mill method and its complex permittivity is measured in X-band (8.2~12.4 GHz) using freespace measurement system. The analytic model is comprised of cube epoxy and perfect sphere agglomeration. The complex permittivity of the agglomeration model is predicted by complex permittivity mixing rule using the measured complex permittivity of epoxy and 1 wt% MWNT added epoxy. Commercial electromagnetic analysis software, CST, is used to obtain S-parameter of the analytic model and MATLAB code is used to calculate complex permittivity from the S-parameter. It is confirmed that the complex permittivity increases when the agglomeration size decreases.

Coupled Analysis with Digimat for Realizing the Mechanical Behavior of Glass Fiber Reinforced Plastics (유리섬유 강화 플라스틱의 역학적 거동 구현을 위한 Digimat와의 연성해석 연구)

  • Kim, Young-Man;Kim, Yong-Hwan
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.32 no.6
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    • pp.349-357
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    • 2019
  • Finite element method (FEM) is utilized in the development of products to realistically analyze and predict the mechanical behavior of materials in various fields. However, the approach based on the numerical analysis of glass fiber reinforced plastic (GFRP) composites, for which the fiber orientation and strain rate affect the mechanical properties, has proven to be challenging. The purpose of this study is to define and evaluate the mechanical properties of glass fiber reinforced plastic composites using the numerical analysis models of Digimat, a linear, nonlinear multi-scale modeling program for various composite materials such as polymers, rubber, metal, etc. In addition, the aim is to predict the behavior of realistic polymeric composites. In this regard, the tensile properties according to the fiber orientation and strain rate of polybutylene terephthalate (PBT) with short fiber weight fractions of 30wt% among various polymers were investigated using references. Information on the fiber orientation was calculated based on injection analysis using Moldflow software, and was utilized in the finite element model for tensile specimens via a mapping process. LS-Dyna, an explicit commercial finite element code, was used for coupled analysis using Digimat to study the tensile properties of composites according to the fiber orientation and strain rate of glass fibers. In addition, the drawbacks and advantages of LS-DYNA's various anisotropic material models were compared and evaluated for the analysis of glass fiber reinforced plastic composites.