• The Bulletin of The Korean Astronomical Society
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• v.37 no.2
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• pp.140.2-140.2
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• 2012

The silicate carbon star IRAS 09425-6040 shows very conspicuous crystalline silicate dust features and excessive emission at far infrared. To investigate properties of dusty envelopes around the object, we use radiative transfer models for axisymmetric and sphericallly symmetric dust distributions. We perform model calculations for various possible combinations of dust shells and disks with various dust species. We compare the model results with the observed spectral energy distributions (SEDs) including the IRAS, ISO, AKARI, MSX and 2MASS data. We find that a model with multiple disks of amorphous and crystalline silicate and multiple spherical shells of carbon dust can reproduce the observed SED fairly well. This supports the scenario for the origin of silicate carbon stars that oxygen-rich material was shed by mass loss when the primary star was an M giant and the O-rich material is stored in a circumbinary disk. Highly (about 75 %) crystallized forsterite dust in the disk can reproduce the conspicuous crystalline features of the ISO observational data. This object looks to have a detached silicate and H2O ice shell with a much higher mass-loss rate. It could be a remnant of the chemical transition phase. The last phase of stellar winds of O-rich materials looks to be a superwind.

• Journal of The Korean Astronomical Society
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• v.38 no.2
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• pp.33-41
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• 2005

We have conducted observations toward the molecular cloud associated with the H II region Sh 156 in $^{13}CO$(J = 1-0), $C^{18}O$(J = 1-0), and CS(J = 2 -1) using the TRAO 14 m telescope. Combining with existing $^{12}CO$(J = 1- 0) data of the Outer Galaxy Survey, we delineated the physical properties of the cloud. We found that there is a significant sign of interaction between the H II region and the molecular gas. We estimated the masses of the molecular cloud, using three different techniques; the most plausible mass is estimated to be $1.37 {\times} 10^5 M_{\bigodot}$, using a conversion factor of $X = 1.9 {\times} 10^{20}\;cm^{-2} (K\;km\;s^{-1})^{-1}$, and this is similar to virial mass estimate. This implies that the cloud is gravitationally bound and in virial equilibrium even though it is closely associated with the H II region. In addition to existing outflow, we found several MSX and IRAS point sources associated with dense core regions. Thus, more star forming activities other than the existing H II region are also going on in this region.

• Annals of Rehabilitation Medicine
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• v.42 no.6
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• pp.884-887
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• 2018

We report a female proband carrying a de novo 5q34-q35.2 deletion breakpoint, and review the unique skeletal phenotype and possible genotype related to this mutation. The patient presented with a persistent head tilt and limited head rotation. Non-contrast-enhanced three-dimensional computed tomography of the cervical spine revealed several malformations including a bone cleft in the right pars interarticularis, a bone defect in both C5 lamina and the transverse foramen at C2-C3, agenesis of the right articular process of C5, bony fusion of C4-C5, and subluxation of the craniocervical joints. Several deformities of the cervical spine seen in this patient have not been associated with the 5q deletion. A review of 5q-related mutations suggests that abnormalities associated with MSX2 gene might cause cervical spine abnormalities.

• Journal of The Korean Astronomical Society
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• v.55 no.6
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• pp.195-205
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• 2022

We investigate infrared properties of OGLE4 Mira variables in our Galaxy. For each object, we cross-identify the AllWISE, 2MASS, Gaia, and IRAS counterparts. We present various IR two-color diagrams (2CDs) and period-magnitude and period-color relations for the Mira variables. Generally, the Mira variables with longer periods are brighter in the IR fluxes and redder in the IR colors. In this work, we also revise and update the previous catalog of AGB stars in our Galaxy using the new sample of OGLE4 Mira variables. Now, we present a new catalog of 74,093 (64,609 O-rich and 9,484 C-rich) AGB stars in our Galaxy. A group of 23,314 (19,196 O-rich and 4,118 C-rich) AGB stars are identified based on the IRAS PSC and another group of 50,779 (45,413 O-rich and 5,366 C-rich) AGB stars are identified based on the AllWISE source catalog. For all of the AGB stars, we cross-identify the IRAS, AKARI, MSX, AllWISE, 2MASS, OGLE4, Gaia, and AAVSO counterparts and present various infrared 2CDs. Comparing the observations with the theory, we find that basic theoretical dust shell models can account for the IR observations fairly well for most of the AGB stars.

• Korean Journal of Cleft Lip And Palate
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• v.10 no.2
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• pp.81-88
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• 2007

Cleft lip and palate (CLP) is one of the most prevalent congenital craniofacial anomalies. It has a significantly greater incidence of dental abnormalities in number, size, shape, and eruption of the teeth. Knout-out mouse model can identify several genes which play an important role in tooth agenesis. Since disruption of these genes has been confirmed to result in tooth agenesis in humans, CLP associated with hypodontia may be the best models for isolated tooth agenesis. According to the studies of dental abnormalities in CLP, the severity of dental defect is known to be influenced by the CLP phenotype. The cumulative data obtained from mouse and human genetic studies indicated that MSX1, PAX9 and AXIN2 are considered as candidate genes in non-syndromic hypodontia, while Shh, Pitx2, Irf6, p63 and EDA pathway genes are involved in syndromic one. We expect that genetic approach of CLP can offer the basis for tooth regeneration and be a new target in hypodontia therapy.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.2
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• pp.80.1-80.1
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• 2014

We made simultaneous surveys of 22 GHz water and 44 / 95 GHz methanol masers toward 299 high-mass protostellar objects using the Korea VLBI Network (KVN) 21-m telescope. The sources were selected from the catalog of Red MSX Source (RMS) survey. Initial selection of the sample present high-mass protostellar objects in an evolutionary phase prior to ultra-compact HII regions, which have bolometric luminosities > $10^3L_{\odot}$ but are not associated with any radio continuum emission. After the follow-up work of ongoing RMS survey, final samples contains 56 sources classified as HII regions. We performed a simultaneous survey of 22 GHz water and 44 GHz methanol masers in 2011 and then conducted a simultaneous survey of 22 GHz water and 44 / 95 GHz methanol masers in 2012. The primary scientific goals of these surveys are to investigate the relationship among the three masers and to explore the relationship between each maser and the central star or the parental dense core. The detection rates of two epochs are 42% and 38% for water, 25% and 26% for 44 GHz methanol, and 23% (2012 only) for 95 GHz methanol masers. We performed a statistical analysis on subsample associated with a large data found in literature. In this poster, we will the preliminary data analysis results and discuss the implications.

• BMB Reports
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• v.43 no.12
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• pp.830-835
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• 2010

Epigenetic modification of the genome through DNA methylation is the key to maintaining the differentiated state of human embryonic stem cells (hESCs), and it must be reset during differentiation by retinoic acid (RA) treatment. A genome-wide methylation/gene expression assay was performed in order to identify epigenetic modifications of RA-treated hESCs. Between undifferentiated and RA-treated hESCs, 166 differentially methylated CpG sites and 2,013 differentially expressed genes were discovered. Combined analysis of methylation and expression data revealed that 19 genes (STAP2, VAMP8, C10orf26, WFIKKN1, ELF3, C1QTNF6, C10orf10, MRGPRF, ARSE, LSAMP, CENTD3, LDB2, POU5F1, GSPT2, THY1, ZNF574, MSX1, SCMH1, and RARB) were highly correlated with each other. The results provided in this study will facilitate future investigations into the interplay between DNA methylation and gene expression through further functional and biological studies.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.429-429
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• 2021

2019년 발생한 인천광역시 붉은 수돗물 사태로 급수구역에 포함된 26만 1천 세대, 63만 5천 명이 직·간접적인 피해를 입은 바 있다. 경제적 피해액으로 추정할 경우 최소 1,280억 원 이상으로 보고된 바 있으며, 이와 같은 상수관망의 수질사고 확산은 장기간 동안 시민의 건강과 생활환경 수준을 저하시킨다. 따라서 상수도시스템의 수질사고확산 모델링 및 방지기술을 통한 수질안전성의 재확인이 필요하며, 이것은 상수도시스템의 지속가능성을 높여 국민이 체감하는 물 환경 수준 제고에 기여가 가능하다. 관망 내 수질해석을 직접적으로 수행하는 모델은 국외적으로 다양하게 개발(PODDS, EPANET-MSX, EPANET2.2 등)된 바 있으나 검·보정을 위한 수질측정 자료 부족 등으로 적용이 제한적이라는 한계가 현재에도 존재한다. 이를 보완하기 위해 수질자료에 비해 그 양이 많고 획득방법이 상대적으로 수월한 수리학적 계측자료 및 해석결과를 활용한 관로 내 체류시간 등을 활용한 연구가 수행된 바 있다. 그러나 이와 같은 수리학적 해석 결과를 활용하는 경우에도 계측자료를 기반으로 한 수리학적 검·보정은 필수적이라 할 수 있다. 본 연구에서는 관로 내 체류시간에 직접적인 영향을 미치는 유량 및 유속자료를 중심으로 수리학적 관망해석의 결과를 최적 검·보정하는 방법론을 제안하였다. 기존 상수관망 수리해석의 검·보정은 일부 지점에서 수압을 측정하고, 수리해석 결과로 도출되는 해당 지점의 수압이 실측된 결과와 유사하도록 관로의 유속계수를 적절히 보정하는 형태로 진행되었다. 그러나 본 연구에서는 관로유량과 유속자료의 목적함수 내 가중치를 수압자료보다 크게 설정하여 체류시간 중심의 검·보정이 수행될 수 있도록 하였으며, 검·보정 대상인자 역시 대수용가의 수요량, 수요패턴, 그리고 관로유속계수로 확장된 모형을 구축하였다. 최적화 기법으로는 메타휴리스틱 기법중 하나인 화음탐색법을 활용하였다. EPANET 2.2 Toolkit과 Visual Basic .Net을 연계하여 프로그래밍하였으며, 개발된 모형을 실제 지방상수도 시스템에 적용하여 분석하였다.

• Journal of the korean Society of Automotive Engineers
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• v.4 no.1
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• pp.20-30
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• 1982

Recent diesel engine has achieved high speed running comparable to that of gasoline engine as a speed improvement effort. Consequently, torsional vibration of high-speed diesel engine induced vibration nosise, reduced horsepower and the like. Viscous damper which is thought to be effective in curtailing the torsional vibration was studied over a wide range of speed. In this investigation, a water cooling, 4-cycle high-speed diesel engine(Msx. 3500 rpm)was used for the study. Theoretical analysis was made by assuming the engine to be an ideal equivalent system(length, moment of inertia) i. e. the multi-degree of freedom equivalent torsional vibration system with damper was analyzed. In the analysis, the inertia moment of suitable damper for this experiment was calculated by varying the relative damping coefficient of damper of engine for each damper. Furthermore, in the torsional vibration experiment, the torsional vibration amplitude of the crankshaft system was measured when the engine was equipped with dampers of different moments of inertia and also when the engine was equipped without dampers. The experimental results were compared with the analytical values and were found to be satisfied. The results of this investigation are summarized below; (1) It was found that for the engine equipped with dampers, the torsional vibration amplitude was reduced to about one third of those without dampers. (2) The optimum value of inertia moment of viscous damper for the engine was found to be about Id=1.05(kg.cm.s$^{2}$) (3) The optimum damping coefficient and the ratio of moment of inertia for the engine were found to be about Ca= 850(kg.cm.s), Rd=0.509, respectively (b1 dapmper).

• Molecules and Cells
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• v.37 no.3
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• pp.220-225
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• 2014

Suppression of bone morphogenetic protein (BMP) signaling induces neural induction in the ectoderm of developing embryos. BMP signaling inhibits neural induction via the expression of various neural suppressors. Previous research has demonstrated that the ectopic expression of dominant negative BMP receptors (DNBR) reduces the expression of target genes down-stream of BMP and leads to neural induction. Additionally, gain-of-function experiments have shown that BMP downstream target genes such as MSX1, GATA1b and Vent are involved in the suppression of neural induction. For example, the Vent1/2 genes are involved in the suppression of Geminin and Sox3 expression in the neural ectodermal region of embryos. In this paper, we investigated whether PV.1, a BMP downstream target gene, negatively regulates the expression of FoxD5b, which plays a role in maintaining a neural progenitor population. A promoter assay and a cyclohexamide experiment demonstrated that PV.1 negatively regulates FoxD5b expression.